Jessica Elisabetta Esposito, Giovanni Annoni, Milena D'Amato, Alessandra Graziosi, Francesca Troilo, Annalisa Di Risio, Gilda Angelini, Caterina Castiglione, Pierluigi Tocco, Paola Volpe, Giancarlo Di Iorio, Giustino Parruti, Ennio Polilli
BACKGROUND: Several results support the hypothesis that a group of pathologies falling within the Neuromyelitis Optica Spectrum Disorders (NMOSD) diagnostic criteria may coexist with Connective Tissue Diseases (CTD) in patients with a high susceptibility to autoimmune conditions. However, the relationship between NMOSD and rheumatologic diseases deserves further investigations to clarify all clinical aspects of this coexistence. We designed a systematic review and a proportional meta-analysis to estimate the association between CTD and MNOSD, with the aim of helping to plan the best strategy to achieve the most significant public health benefit for these conditions...
February 18, 2024: Journal of Integrative Neuroscience