journal
https://read.qxmd.com/read/38413489/the-invisible-effect-of-recruitment-maneuvers-in-acute-brain-injury
#1
EDITORIAL
Paul Nyquist
No abstract text is available yet for this article.
February 27, 2024: Neurocritical Care
https://read.qxmd.com/read/38396279/current-concepts-in-early-mobilization-of-critically-ill-patients-within-the-context-of-neurologic-pathology
#2
REVIEW
Thaís Ferreira Lopes Diniz Maia, Paulo André Freire Magalhães, Dasdores Tatiana Silva Santos, Jorge Luiz de Brito Gomes, Paulo Adriano Schwingel, Aline de Freitas Brito
Neurocritical patients (NCPs) in the intensive care unit (ICU) rapidly progress to respiratory and peripheral muscle dysfunctions, which significantly impact morbidity and death. Early mobilization in NCPs to decrease the incidence of ICU-acquired weakness has been showing rapid growth, although pertinent literature is still scarce. With this review, we summarize and discuss current concepts in early mobilization of critically ill patients within the context of neurologic pathology in NCPs. A narrative synthesis of literature was undertaken trying to answer the following questions: How do the respiratory and musculoskeletal systems in NCPs behave? Which metabolic biomarkers influence physiological responses in NCPs? Which considerations should be taken when prescribing exercises in neurocritically ill patients? The present review detected safety, feasibility, and beneficial response for early mobilization in NCPs, given successes in other critically ill populations and many smaller intervention trials in neurocritical care...
February 23, 2024: Neurocritical Care
https://read.qxmd.com/read/38379105/a-feed-back-on-eeg-monitoring-artifacts
#3
JOURNAL ARTICLE
Julie Lévi-Strauss, Virginie Lambrecq, Nicolas Weiss, Lucas Di Meglio
No abstract text is available yet for this article.
February 20, 2024: Neurocritical Care
https://read.qxmd.com/read/38379104/sex-differences-in-perihematomal-edema-volume-and-outcome-after-intracerebral-hemorrhage
#4
JOURNAL ARTICLE
Jens Witsch, Quy Cao, Jae W Song, Yunshi Luo, Kelly L Sloane, Aaron Rothstein, Christopher G Favilla, Brett L Cucchiara, Scott E Kasner, Steve R Messé, Huimahn A Choi, Louise D McCullough, Stephan A Mayer, Aaron M Gusdon
BACKGROUND: Although larger hematoma volume is associated with worse outcome after intracerebral hemorrhage (ICH), the association between perihematomal edema (PHE) volume and outcome remains uncertain, as does the impact of sex on PHE and outcome. Here we aimed to determine whether larger PHE volume is associated with worse outcome and whether PHE volume trajectories differ by sex. METHODS: We conducted a post hoc analysis of the Factor VIIa for Acute Hemorrhagic Stroke Treatment (FAST) trial, which randomized patients with ICH to receive recombinant activated factor VIIa or placebo...
February 20, 2024: Neurocritical Care
https://read.qxmd.com/read/38379103/safety-and-effect-on-intracranial-pressure-of-3-hypertonic-saline-bolus-via-peripheral-intravenous-catheter-for-neurological-emergencies
#5
JOURNAL ARTICLE
Farid Khasiyev, Abdullah Hakoun, Kara Christopher, James Braun, Fajun Wang
BACKGROUND: Elevated intracranial pressure (ICP) is a neurological emergency in patients with acute brain injuries. Such a state requires immediate and effective interventions to prevent potential neurological deterioration. Current clinical guidelines recommend hypertonic saline (HTS) and mannitol as first-line therapeutic agents. Notably, HTS is conventionally administered through central venous catheters (CVCs), which may introduce delays in treatment due to the complexities associated with CVC placement...
February 20, 2024: Neurocritical Care
https://read.qxmd.com/read/38366278/icp-monitoring-for-bacterial-meningitis-is-this-just-one-of-the-blind-spots-in-neurocritical-care
#6
EDITORIAL
Jose Javier Provencio
No abstract text is available yet for this article.
February 17, 2024: Neurocritical Care
https://read.qxmd.com/read/38366277/guidelines-for-neuroprognostication-in-critically-ill-adults-with-moderate-severe-traumatic-brain-injury
#7
REVIEW
Susanne Muehlschlegel, Venkatakrishna Rajajee, Katja E Wartenberg, Sheila A Alexander, Katharina M Busl, Claire J Creutzfeldt, Gabriel V Fontaine, Sara E Hocker, David Y Hwang, Keri S Kim, Dominik Madzar, Dea Mahanes, Shraddha Mainali, Juergen Meixensberger, Oliver W Sakowitz, Panayiotis N Varelas, Christian Weimar, Thomas Westermaier
BACKGROUND: Moderate-severe traumatic brain injury (msTBI) carries high morbidity and mortality worldwide. Accurate neuroprognostication is essential in guiding clinical decisions, including patient triage and transition to comfort measures. Here we provide recommendations regarding the reliability of major clinical predictors and prediction models commonly used in msTBI neuroprognostication, guiding clinicians in counseling surrogate decision-makers. METHODS: Using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology, we conducted a systematic narrative review of the most clinically relevant predictors and prediction models cited in the literature...
February 17, 2024: Neurocritical Care
https://read.qxmd.com/read/38356080/assessing-acute-brain-injury-after-rapid-reduction-of-paco-2-using-plasma-biomarkers-in-patients-undergoing-ecmo
#8
EDITORIAL
Sung-Min Cho, Aaron M Gusdon
No abstract text is available yet for this article.
February 14, 2024: Neurocritical Care
https://read.qxmd.com/read/38356079/temporal-changes-in-csf-cell-parameters-after-sah-comparison-of-ventricular-and-spinal-drain-samples
#9
JOURNAL ARTICLE
Jyri J Virta, Jarno Satopää, Teemu Luostarinen, Jaakko Kaprio, Mika Niemelä, Miikka Korja, Rahul Raj
BACKGROUND: Forty percent of patients with aneurysmatic subarachnoid hemorrhage (aSAH) develop acute hydrocephalus requiring treatment with cerebrospinal fluid (CSF) drainage. CSF cell parameters are used in the diagnosis of nosocomial infections but also reflect sterile inflammation after aSAH. We aimed to study the temporal changes in CSF parameters and compare external ventricular drain (EVD)-derived and lumbar spinal drain-derived samples. METHODS: We retrospectively identified consecutive patients with aSAH treated at our neurointensive care unit between January 2014 and May 2019...
February 14, 2024: Neurocritical Care
https://read.qxmd.com/read/38356078/necrotizing-pneumonia-and-cerebral-air-embolism
#10
JOURNAL ARTICLE
Kai Michael Schubert, Marie-Eve Jaquier
No abstract text is available yet for this article.
February 14, 2024: Neurocritical Care
https://read.qxmd.com/read/38356077/detection-and-management-of-elevated-intracranial-pressure-in-the-treatment-of-acute-community-acquired-bacterial-meningitis-a-systematic-review
#11
REVIEW
Victor Gabriel El-Hajj, Ingrid Pettersson, Maria Gharios, Abdul Karim Ghaith, Mohamad Bydon, Erik Edström, Adrian Elmi-Terander
Acute bacterial meningitis (ABM) is associated with severe morbidity and mortality. The most prevalent pathogens in community-acquired ABM are Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Other pathogens may affect specific patient groups, such as newborns, older patients, or immunocompromised patients. It is well established that ABM is associated with elevated intracranial pressure (ICP). However, the role of ICP monitoring and management in the treatment of ABM has been poorly described...
February 14, 2024: Neurocritical Care
https://read.qxmd.com/read/38351299/the-effect-of-recruitment-maneuvers-on-cerebrovascular-dynamics-and-right-ventricular-function-in-patients-with-acute-brain-injury-a-single-center-prospective-study
#12
JOURNAL ARTICLE
Filippo Sanfilippo, Agnieszka Uryga, Lorenzo Ball, Denise Battaglini, Ida Giorgia Iavarone, Peter Smielewski, Erta Beqiri, Marek Czosnyka, Nicolò Patroniti, Chiara Robba
BACKGROUND: Optimization of ventilatory settings is challenging for patients in the neurointensive care unit, requiring a balance between precise gas exchange control, lung protection, and managing hemodynamic effects of positive pressure ventilation. Although recruitment maneuvers (RMs) may enhance oxygenation, they could also exert profound undesirable systemic impacts. METHODS: The single-center, prospective study investigated the effects of RMs (up-titration of positive end-expiratory pressure) on multimodal neuromonitoring in patients with acute brain injury...
February 13, 2024: Neurocritical Care
https://read.qxmd.com/read/38351298/quantitative-pupillometry-for-intracranial-pressure-icp-monitoring-in-traumatic-brain-injury-a-scoping-review
#13
REVIEW
Karol Martínez-Palacios, Sebastián Vásquez-García, Olubunmi A Fariyike, Chiara Robba, Andrés M Rubiano
The neurological examination has remained key for the detection of worsening in neurocritical care patients, particularly after traumatic brain injury (TBI). New-onset, unreactive anisocoria frequently occurs in such situations, triggering aggressive diagnostic and therapeutic measures to address life-threatening elevations in intracranial pressure (ICP). As such, the field needs objective, unbiased, portable, and reliable methods for quickly assessing such pupillary changes. In this area, quantitative pupillometry (QP) proves promising, leveraging the analysis of different pupillary variables to indirectly estimate ICP...
February 13, 2024: Neurocritical Care
https://read.qxmd.com/read/38332336/aneurysmal-subdural-hematoma-a-systematic-review
#14
REVIEW
Mohammad Aladawi, Mohamed Elfil, Zaid R Najdawi, Hazem Ghaith, Harlan Sayles, William Thorell, Maximiliano A Hawkes
BACKGROUND: Aneurysmal subdural hematoma (aSDH) is a rare complication of aneurysm rupture, affecting between 0.5 and 7.9% of patients with aneurysmal subarachnoid hemorrhage (aSAH). The clinical presentation, course, and outcomes of these patients are largely unknown. OBJECTIVE: This study aims to systematically review the literature to evaluate the demographics, clinical presentation, aneurysm location, treatment options, and outcomes of patients with aSDH with and without aSAH...
February 8, 2024: Neurocritical Care
https://read.qxmd.com/read/38332335/idiosyncrasies-of-outcome-grading-after-brain-injury-past-into-the-present
#15
EDITORIAL
Eelco F M Wijdicks
No abstract text is available yet for this article.
February 8, 2024: Neurocritical Care
https://read.qxmd.com/read/38326536/continuous-monitoring-of-cerebral-autoregulation-in-adults-supported-by-extracorporeal-membrane-oxygenation
#16
JOURNAL ARTICLE
Lucy Q Zhang, Henry Chang, Andrew Kalra, Mariyam Humayun, Kathryn R Rosenblatt, Vishank A Shah, Romergryko G Geocadin, Charles H Brown, Bo Soo Kim, Glenn J R Whitman, Lucia Rivera-Lara, Sung-Min Cho
BACKGROUND: Impaired cerebral autoregulation (CA) is one of several proposed mechanisms of acute brain injury in patients supported by extracorporeal membrane oxygenation (ECMO). The primary aim of this study was to determine the feasibility of continuous CA monitoring in adult ECMO patients. Our secondary aims were to describe changes in cerebral oximetry index (COx) and other metrics of CA over time and in relation to functional neurologic outcomes. METHODS: This is a single-center prospective observational study...
February 7, 2024: Neurocritical Care
https://read.qxmd.com/read/38326535/cerebral-hemodynamics-and-levosimendan-use-in-patients-with-cerebral-vasospasm-and-subarachnoid-hemorrhage-an-observational-perfusion-ct-based-imaging-study
#17
JOURNAL ARTICLE
Grégoire Cane, Hugues de Courson, Caroline Robert, Hikaru Fukutomi, Gaultier Marnat, Thomas Tourdias, Matthieu Biais
BACKGROUND: Delayed cerebral ischemia associated with cerebral vasospasm (CVS) in aneurysmal subarachnoid hemorrhage significantly affects patient prognosis. Levosimendan has emerged as a potential treatment, but clinical data are lacking. The aim of this study is to decipher levosimendan's effect on cerebral hemodynamics by automated quantitative measurements of brain computed tomography perfusion (CTP). METHODS: We conducted a retrospective analysis of a database of a neurosurgical intensive care unit...
February 7, 2024: Neurocritical Care
https://read.qxmd.com/read/38316737/correction-broad-range-eubacterial-polymerase-chain-reaction-of-cerebrospinal-fluid-reduces-the-time-to-exclusion-of-and-costs-associated-with-ventriculostomy-related-infection-in-hemorrhagic-stroke
#18
Elisabeth Pietrzko, Stefan Bögli, Katja Frick, Sabeth Ebner-Dietler, Crescenzo Capone, Frank Imkamp, Hendrik Koliwer-Brandl, Nicolas Müller, Emanuela Keller, Giovanna Brandi
No abstract text is available yet for this article.
February 5, 2024: Neurocritical Care
https://read.qxmd.com/read/38316736/systemic-immune-inflammation-response-is-associated-with-futile-recanalization-after-endovascular-treatment
#19
JOURNAL ARTICLE
Guojuan Chen, Anxin Wang, Xiaoli Zhang, Yuhao Li, Xue Xia, Xue Tian, Jing Li, Zhongrong Miao, Wei Yue
BACKGROUND: Frequent incidence of futile recanalization decreases the benefit of endovascular treatment (EVT) in acute ischemic stroke. We hypothesized that the inflammation and immune response after ischemic are associated with futile recanalization. We aimed to investigate the correlation of admission systemic immune-inflammation index (SII) with futile recanalization post EVT. METHODS: Patients with successful recanalization (modified Thrombolysis in Cerebral Ischemia angiographic score 2b-3) and maintained artery recanalized after 24 h of EVT were chosen from a prospective nationwide registry study...
February 5, 2024: Neurocritical Care
https://read.qxmd.com/read/38316735/guidelines-for-seizure-prophylaxis-in-adults-hospitalized-with-moderate-severe-traumatic-brain-injury-a-clinical-practice-guideline-for-health-care-professionals-from-the-neurocritical-care-society
#20
JOURNAL ARTICLE
Jennifer A Frontera, Emily J Gilmore, Emily L Johnson, DaiWai Olson, Appaji Rayi, Eljim Tesoro, Jamie Ullman, Yuhong Yuan, Sahar F Zafar, Shaun Rowe
BACKGROUND: There is practice heterogeneity in the use, type, and duration of prophylactic antiseizure medications (ASMs) in patients with moderate-severe traumatic brain injury (TBI). METHODS: We conducted a systematic review and meta-analysis of articles assessing ASM prophylaxis in adults with moderate-severe TBI (acute radiographic findings and requiring hospitalization). The population, intervention, comparator, and outcome (PICO) questions were as follows: (1) Should ASM versus no ASM be used in patients with moderate-severe TBI and no history of clinical or electrographic seizures? (2) If an ASM is used, should levetiracetam (LEV) or phenytoin/fosphenytoin (PHT/fPHT) be preferentially used? (3) If an ASM is used, should a long versus short (> 7 vs...
February 5, 2024: Neurocritical Care
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