Ophthalmic Surgery, Lasers & Imaging

BACKGROUND AND OBJECTIVE: To determine effect of surgeon experience on outcomes of LASIK. PATIENTS AND METHODS: Retrospective case series of myopic femtosecond LASIK performed by residents and fellows compared to an attending surgeon, with mean follow-up of 6.6 months. RESULTS: Seventy-two eyes (38 patients) had LASIK performed by a trainee and 157 eyes (83 patients) by an attending surgeon. There were no statistically significant preoperative differences...

BACKGROUND AND OBJECTIVE: To describe the use of anterior segment optical coherence tomography (AS-OCT) in studying the dynamic changes of the anterior chamber angle by corneal indentation. PATIENTS AND METHODS: In a prospective observational study, the anterior segments of 21 eyes were imaged using AS-OCT. After the initial scan, a second scan was executed on the same areas with a central corneal indentation. An evaluation of the reopening of the angle and its measurement were performed...

BACKGROUND AND OBJECTIVE: To evaluate the intrasession reproducibility of the peripapillary retinal nerve fiber layer (RNFL) thickness measurements obtained by spectral-domain optical coherence tomography (SD-OCT) in eyes with keratoconus and normal eyes. PATIENTS AND METHODS: Peripapillary RNFL thickness measurements with SD-OCT were repeated three times during the same visit using the eye tracker and retest function in one eye of each participant. Reproducibility was evaluated using within-subject standard deviation (Sw), coefficient of variation (CV), and intraclass correlation coefficient (ICC)...

BACKGROUND AND OBJECTIVE: To identify the correlation between retinal nerve fiber layer (RNFL) thickness and visual field sensitivity in healthy eyes with preperimetric and perimetric glaucoma and to estimate the functional RNFL loss in eyes with pre-perimetric glaucoma. PATIENTS AND METHODS: One hundred and two eyes with glaucoma and diffuse RNFL atrophy and 102 healthy eyes were enrolled. The correlation between optical coherence tomography (OCT)-measured RNFL thickness of the superior (clock-hour segments 10, 11, 12, 1, 2, and 3) and inferior (clock-hour segments 5, 6, 7, and 8) area and the average total deviations of the inferior and superior hemifields in standard automated perimetry (SAP) were evaluated using the simple linear model, respectively...

BACKGROUND AND OBJECTIVE: To compare rates of abnormal peripapillary retinal nerve fiber layer (RNFL) and macular ganglion cell layer scans acquired with Cirrus HD-OCT (Carl Zeiss Meditec, Inc., Dublin, CA) and RTVue-100 (Optovue Inc., Fremont, CA) in healthy myopic eyes. PATIENTS AND METHODS: Forty-one non-glaucomatous myopic eyes (41 individuals) were scanned with Cirrus to measure RNFL and ganglion cell-inner plexiform layer (GCIPL) and with RTVue to measure peripapillary RNFL and ganglion cell complex (GCC) thicknesses...

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BACKGROUND AND OBJECTIVE: Intraoperative use of spectral-domain optical coherence tomography (SD-OCT) using an OCT-mounted surgical microscope could provide additional information to predict visual outcomes of macular surgery and identify intraoperative changes in the macular anatomy that affect visual recovery. PATIENTS AND METHODS: This interventional retrospective case study included 5 eyes of 5 consecutive patients with various macular pathologies. All patients underwent the standard surgery for idiopathic macular holes and epiretinal membranes (ERMs) using the same 25-gauge three-port pars plana technique...

BACKGROUND AND OBJECTIVE: To investigate the morphological substrate of the changes in visual function in eyes with retinitis pigmentosa and good visual acuity using spectral-domain optical coherence tomography (SD-OCT). PATIENTS AND METHODS: A total of 30 eyes of 17 patients with retinitis pigmentosa and visual acuity of 20/40 or better underwent contrast sensitivity and color vision testing. The retinal thickness at the fovea and macula and the length of the photoreceptor inner/outer segment (IS/OS) junction were assessed by SD-OCT...

BACKGROUND AND OBJECTIVE: To measure macular choroidal thickness (CT) using spectral-domain optical coherence tomography (OCT) and to investigate the correlation between CT and age, degree of myopia, and history of macular choroidal neovascularization (CNV). PATIENTS AND METHODS: A cross-sectional study included 187 highly myopic eyes of 187 patients examined between January and December 2010. The choroid was imaged with spectral-domain OCT by changing the reference position from the vitreous to the choroid...

BACKGROUND AND OBJECTIVE: To investigate the performance of an automated foveal center detection algorithm on spectral-domain optical coherence tomography (SD-OCT). PATIENTS AND METHODS: Fifty normal eyes and 50 eyes with early stage dry age-related macular degeneration (AMD) were analyzed. The actual scan center (SC), automatically detected foveal center (AF), and manually identified foveal center (MF) were compared. RESULTS: The mean of the radial distances was 89 ± 120 μm from MF to SC and 54 ± 41 μm from MF to AF for normal eyes and 179 ± 125 μm from SC to MF and 104 ± 62 μm from AF to MF for eyes with AMD...

A 55-year-old woman with extensive retinal crystalline deposition secondary to primary hyperoxaluria presented with bilateral loss of vision secondary to oxalate retinopathy. Enhanced depth imaging optical coherence tomography revealed intraretinal, subretinal, and intraretinal and subretinal pigment epithelium, and choroidal focal hyperreflective structures consistent with both neurosensory and uveal deposition of oxalate crystals. Serial optical coherence tomography revealed continued crystalline deposition with progressive retinal atrophy...

High-resolution spectral-domain optical coherence tomography of a patient affected by acute macular edema secondary to preeclampsia is described. The particular optical coherence tomography pattern was characterized by bilateral macular edema with a tent-shaped organization, associated with massive neurosensorial retinal detachment. Many hyperreflective irregular dots were evident in the context of a subfoveal clear cystic lesion. A different hyperreflective irregularity was detected in the retinal pigment epithelium...

Optimal management of posterior segment disorders requires a high-resolution and preferably noninvasive imaging tool for better definition of diseases. High-resolution optical coherence tomography can provide noninvasive, high-definition imaging of the posterior segment, allowing earlier diagnosis, better follow-up of chronic cases, and more accurate and timely monitoring of the effect of therapeutic agents. Recent findings suggest an individualized approach to vitreoretinal and choroidal diseases is possible based not only on traditional ophthalmic investigations, but also on high-resolution optical coherence tomography...

BACKGROUND AND OBJECTIVE: To evaluate femtosecond laser-created tunnels intraoperatively by anterior segment optical coherence tomography (AS-OCT) during intrastromal corneal ring segment implantation. PATIENTS AND METHODS: The study prospectively examined 13 eyes of 11 patients who underwent intrastromal corneal ring segment surgery with the aid of femtosecond laser. All eyes had keratoconus as the primary diagnosis. Eyes were examined by AS-OCT to image the tunnel immediately after femtosecond laser and before ring segment implantation...

BACKGROUND AND OBJECTIVE: To compare the architecture of single plane self-sealing clear corneal incision (SP-CCI) and shallow grooved self-sealing clear corneal incision (SG-CCI) after cataract surgery using Fourier-domain optical coherence tomography (FD-OCT). PATIENTS AND METHODS: An FD-OCT system with a corneal adaptor module was used to image the corneal incisions in radial sections in 44 eyes. A line scan pattern was used to measure the corneal incision, positioning the caliper mark perpendicular to the limbus...

The authors describe "iris-assisted," open-sky, continuous curvilinear capsulorhexis (CCC) in a triple procedure combining corneal transplantation, cataract extraction, and intraocular lens implantation. They do not use miotics or mydriatics. Patients receive oral acetazolamide (250 mg), intravenous mannitol (5 mL/kg), and Honan balloon at 30 mm Hg for 20 to 30 minutes before surgery. After trephination and excision of recipient cornea, the pupil assumes a mid-dilated position. After injection of 2.3% hyaluronic acid into the anterior chamber, a central linear incision is made in the anterior capsule using a cystotome needle and a CCC is made (approximately 5...

BACKGROUND AND OBJECTIVE: To assess the incidence of elevated intraocular pressure (IOP) in the early postoperative period after excimer laser penetrating keratoplasty for keratoconus and reveal potential associations with anterior segment parameters. PATIENTS AND METHODS: This prospective, interventional study consisted of 40 patients with keratoconus who were treated with excimer laser penetrating keratoplasty. Corneal pachymetry, anterior chamber depth, anterior chamber volume, and anterior segment angle were measured by Scheimpflug camera preoperatively and 2 months postoperatively...

BACKGROUND AND OBJECTIVE: To report the position of the single-piece and three-piece intraocular lenses (IOLs) following in-the-bag implantation. PATIENTS AND METHODS: Forty patients with bilateral age-related cataracts were recruited from both tertiary hospital and private practice in Montréal, Canada. Patients received the single-piece IOL in one eye and the three-piece IOL contralaterally. Postoperative anterior chamber depth (ACD) and iris-to-IOL distance were evaluated using a Scheimpflug imaging system...

The authors introduce a new technique for scleral fixation using a standard capsular tension ring for in-the-bag use in patients with a lens dislocated by more than 180°. Three patients with zonulysis and phacodonesis underwent surgery with this technique, and all of the patients showed stable maintenance in visual acuity after an average of 22.7 months (range: 14 to 30 months) of follow-up. None of them showed any serious postoperative complications. This technique appears to be safe and effective in terms of lens stability and visual rehabilitation...

BACKGROUND AND OBJECTIVE: To investigate the findings of a tissue layer image of the photoreceptor layer, or photoreceptor layer map (PLM), using spectral-domain optical coherence tomography (SD-OCT) in central serous chorioretinopathy (CSC). PATIENTS AND METHODS: Data scanned using SD-OCT in CSC were processed to obtain PLMs, which were analyzed and compared with fluorescein angiography and OCT. RESULTS: Among 72 eyes of 69 patients, PLMs depicted subretinal fluid as distinct hyporeflective areas in 71 eyes (98...