Axelle Brulport, Mathilde Bourdon, Daniel Vaiman, Christian Drouet, Khaled Pocate-Cheriet, Kheira Bouzid, Louis Marcellin, Pietro Santulli, Carole Abo, Maxime Jeljeli, Sandrine Chouzenoux, Charles Chapron, Frédéric Batteux, Camille Berthelot, Ludivine Doridot
Biomarker identification could help in deciphering endometriosis pathophysiology in addition to their use in the development of non invasive diagnostic and prognostic approaches, that are essential to greatly improve patient care. Despite extensive efforts, no single potential biomarker or combination has been clinically validated for endometriosis.Many studies have investigated endometriosis-associated biological markers in specific tissues, but an integrative approach across tissues is lacking. The aim of this review is to propose a comprehensive overview of identified biomarkers based on tissue or biological compartment, while taking into account endometriosis phenotypes (superficial, ovarian or deep, or rASRM stages), menstrual cycle phases, treatments and symptoms...
February 10, 2024: Reproductive Biology and Endocrinology: RB&E