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Hepatobiliary & Pancreatic Diseases International: HBPD INT

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https://read.qxmd.com/read/30772209/new-insights-in-the-management-of-the-middle-hepatic-vein-dilemma
#1
EDITORIAL
Quirino Lai, Fabio Melandro, Gianluca Mennini, Massimo Rossi
No abstract text is available yet for this article.
February 1, 2019: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30772208/blumgart-s-technique-of-pancreaticojejunostomy-analysis-of-safety-and-outcomes
#2
Vishal Gupta, Saket Kumar, Vivek Gupta, Pradeep Joshi, Rahul Rahul, Rakesh Kumar Yadav, Amit Dangi, Abhijit Chandra
BACKGROUND: Blumgart's pancreaticojejunostomy (PJ) has been described with low pancreatic leak rates. This study aimed to evaluate our experience with this technique regarding the pancreatic leak and other perioperative outcomes. METHODS: We performed a single-center retrospective analysis of a cohort of 81 patients who underwent pancreaticoduodenectomy in our department from January 2011 to February 2018. The primary endpoint was the occurrence of a clinically relevant postoperative pancreatic fistula (CR-POPF) and analysis of its risk factors...
January 31, 2019: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30738719/middle-hepatic-vein-reconstruction-in-adult-right-lobe-living-donor-liver-transplantation-improves-recipient-survival
#3
Hai-Jun Guo, Kun Wang, Kang-Chen Chen, Zhi-Kun Liu, Abdulahad Al-Ameri, Yan Shen, Xiao Xu, Shu-Sen Zheng
BACKGROUND: The efficacy and necessity of middle hepatic vein (MHV) reconstruction in adult-to-adult right lobe living donor liver transplantation (LDLT) remain controversial. The present study aimed to evaluate the survival beneficiary of MHV reconstructions in LDLT. METHODS: We compared the clinical outcomes of liver recipients with MHV reconstruction (n = 101) and without MHV reconstruction (n = 43) who underwent LDLT using right lobe grafts at our institution from January 2006 to May 2017...
January 31, 2019: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30718181/loco-regional-hcc-treatment-services-as-a-bridge-to-liver-transplantation
#4
Sophia Schmitz, Georg Lurje, Florian Ulmer, Anne Andert, Philipp Bruners, Maximilian Schulze-Hagen, Ulf Neumann, Wenzel Schoening
BACKGROUND: Liver transplantation remains the main curative treatment option for hepatocellular carcinoma (HCC) patients. In the Eurotransplant area Milan criteria are used to assign priority extra points (exceptional MELD, exMELD) for patients on the waiting list. To prevent patients from tumor progression, loco-regional (neoadjuvant) treatment (LRT) is used. For patients unlikely to timely receive an organ via primary allocation, "extended critera donor (ECD) organs" are used...
January 21, 2019: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30692043/alteration-of-oncogenic-igf-ii-gene-methylation-status-associates-with-hepatocyte-malignant-transformation
#5
Bo-Jun Tai, Min Yao, Wen-Jie Zheng, Yu-Cheng Shen, Li Wang, Jian-Ying Sun, Meng-Na Wu, Zhi-Zhen Dong, Deng-Fu Yao
BACKGROUND: Oncogenic insulin-like growth factor-II (IGF-II) is overexpressed in hepatocellular carcinoma (HCC). The present study aimed to analyze the dynamic alteration of IGF-II CpG site methylation status and its molecular mechanism in HCC progression. METHODS: IGF-II alterations were observed in rat hepatocarcinogenesis models induced by 2-acetylaminofluorene. Liver IGF-II expression was compared by immunohistochemistry or tissue IGF-II specific concentration (nmol/mg protein)...
January 21, 2019: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30686653/should-we-invariably-follow-the-current-guidelines-to-treat-our-hcc-patients
#6
LETTER
Wen-Tao Yan, Bing Quan, Jiong-Jie Yu, Tian Yang
No abstract text is available yet for this article.
January 21, 2019: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30661942/relationship-between-intestinal-microbial-dysbiosis-and-primary-liver-cancer
#7
Lei Zhang, Yong-Na Wu, Tuo Chen, Cheng-Hui Ren, Xun Li, Guang-Xiu Liu
BACKGROUND: Intestinal microbial dysbiosis is involved in liver disease pathogenesis. However, its role in primary liver cancer (PLC), particularly in hepatocarcinogenesis remains unclear. The present study aimed to study the changes in intestinal flora at various stages of PLC and clarify the relationship between intestinal microbes and PLC. METHODS: Twenty-four patients with PLC (PLC group), 24 patients with liver cirrhosis (LC group), and 23 healthy control individuals (HC group) were enrolled from October 2016 to October 2017...
January 4, 2019: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30655073/is-irreversible-electroporation-safe-and-effective-in-the-treatment-of-hepatobiliary-and-pancreatic-cancers
#8
REVIEW
Li-Ming Wu, Le-Le Zhang, Xin-Hua Chen, Shu-Sen Zheng
BACKGROUND: Irreversible electroporation (IRE) is a novel ablative technique for hepatobiliary and pancreatic cancers. This review summarizes the data regarding the safety and efficacy of IRE in the treatment of hepatobiliary and pancreatic cancers. DATA SOURCES: Studies were identified by searching PubMed and Embase for articles published in English from database inception through July 31, 2017. For inclusion, each clinical study had to report morbidity and survival data on hepatobiliary and pancreatic cancers treated with IRE and contain at least 10 patients...
January 4, 2019: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30612929/kml001-an-arsenic-compound-as-salvage-chemotherapy-in-refractory-biliary-tract-cancers-a-prospective-study
#9
Jung Hyun Jo, Huapyong Kang, Hee Seung Lee, Moon Jae Chung, Jeong Youp Park, Seungmin Bang, Seung Woo Park, Si Young Song
BACKGROUND: Sodium meta-arsenite (NaAsO2 , KML001) is a potential oral anticancer agent acting on telomerase and telomere length. This prospective study evaluated its safety, tolerability, and effectiveness as salvage chemotherapy in patients with advanced biliary tract cancer (BTC) resistant to gemcitabine-based chemotherapy. METHODS: Forty-four patients (21 women and 23 men) with advanced BTC and failure history of gemcitabine-based chemotherapy, performance status (PS) 0-2, normal cardiac, hepatic, and renal function were enrolled...
December 28, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30612928/clinical-outcomes-of-endoscopic-ultrasonography-guided-transmural-drainage-using-plastic-stent-and-nasocystic-drain-for-pancreatic-and-peripancreatic-collections
#10
LETTER
Katsuya Kitamura, Akira Yamamiya, Yu Ishii, Yuta Mitsui, Hitoshi Yoshida
No abstract text is available yet for this article.
December 28, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30583855/increasing-pancreatic-cancer-is-not-paralleled-by-pancreaticoduodenectomy-volumes-in-brazil-a-time-trend-analysis
#11
Lucila M Perrotta de Souza, Jessica Pl Moreira, Homero S Fogaça, José Marcus Raso Eulálio, Ronir R Luiz, Heitor Sp de Souza
BACKGROUND: Currently, surgical resection represents the only curative treatment for pancreatic cancer (PC), however, the majority of tumors are no longer resectable by the time of diagnosis. The aim of this study was to describe time trends and distribution of pancreaticoduodenectomies (PDs) performed for treating PC in Brazil in recent years. METHODS: Data were retrospectively obtained from Brazilian Health Public System (namely DATASUS) regarding hospitalizations for PC and PD in Brazil from January 2008 to December 2015...
December 10, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30579735/the-successful-treatment-for-cardiac-tamponade-during-radiofrequency-ablation-of-hepatocellular-carcinoma
#12
LETTER
Chen Xue, Zhigang Ren, Xiaobo Hu, Yuting He, Ranran Sun, Juan Li, Guangying Cui, Zujiang Yu
No abstract text is available yet for this article.
December 10, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30573300/enhanced-recovery-after-surgery-protocol-enhances-early-postoperative-recovery-after-pancreaticoduodenectomy
#13
Ramasamy Mahendran, Mallika Tewari, Vinod Kumar Dixit, Hari Shankar Shukla
BACKGROUND: Enhanced recovery after surgery (ERAS) protocol is a multimodal, multidisciplinary and evidence-based approach to reduce surgical stress and enhance recovery in the postoperative period. This study aimed to analyze the outcome of ERAS protocol in patients after pancreaticoduodenectomy (PD). METHODS: A total of 50 consecutive patients with pancreatic/periampullary cancer who underwent PD between January 2016 to August 2017 were included in the study. As per the institute ERAS protocol, nasogastric tube (NGT) was removed on postoperative day (POD) 1 if output was less than 200 mL and oral sips were allowed; oral liquids were allowed on POD2; semisolid diet by POD3; abdominal drain was removed on POD 4 if output was less than 100 mL with no evidence of postoperative pancreatic fistula (POPF); normal diet was allowed on POD5...
December 10, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30579736/the-role-of-graft-reperfusion-sequence-in-the-development-of-non-anastomotic-biliary-strictures-following-orthotopic-liver-transplantation-a-meta-analysis
#14
Mohamed Bekheit, Matteo Catanzano, Stuart Shand, Irfan Ahmed, ELSaid ELKayal, Gihan Mohamed Shehata, Adel Zaki
BACKGROUND: Liver transplant is a potential cure for liver failure and hepatic malignancy but there are many techniques which have been described for vascular reconstruction. This study was to compare the prevalence of non-anastomotic biliary stricture and other surgical complications based on Clavien-Dindo scoring system, in initial portal reperfusion (sequential) versus simultaneous or initial artery reperfusion. DATA SOURCES: Meta-analysis of published studies comparing the outcomes of both techniques was carried out...
December 6, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30573299/hydrogen-rich-saline-protects-against-hepatic-injury-induced-by-ischemia-reperfusion-and-laparoscopic-hepatectomy-in-swine
#15
Yan-Song Ge, Qian-Zhen Zhang, Hui Li, Ge Bai, Zhi-Hui Jiao, Hong-Bin Wang
BACKGROUND: Hydrogen-rich saline (HRS) has antioxidative, anti-inflammatory and anti-apoptotic properties. We investigated the effects of hydrogen on hepatic ischemia-reperfusion (I/R) and laparoscopic hepatectomy in swine. METHODS: Twenty-one healthy Bama miniature pigs were randomly divided into the sham group, ischemia-reperfusion injury (IRI) group, HRS-5 (5 mL/kg) group, and HRS-10 (10 mL/kg) group. HRS was injected through the portal vein 10 min before reperfusion and at postoperative day 1, 2 and 3...
December 6, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30558838/novel-non-invasive-score-to-predict-cirrhosis-in-the-era-of-hepatitis-c-elimination-a-population-study-of-ex-substance-users-in-singapore
#16
Yue Zhao, Prem Harichander Thurairajah, Rahul Kumar, Jessica Tan, Eng Kiong Teo, John Chen Hsiang
BACKGROUND: Chronic hepatitis C infection is common among people with history of substance use. Liver fibrosis assessment is a barrier to linkage to care, particularly among those with history of substance users. The use of non-invasive scores can be helpful in predicting liver cirrhosis in the era of HCV elimination, especially in countries where transient elastography (TE) is not available. We compared the commonly used non-invasive scores with a novel non-invasive score in predicting liver cirrhosis in this population...
December 6, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30554831/primary-hepatic-squamous-cell-carcinoma-with-abdominal-incision-metastasis-after-hepatectomy
#17
LETTER
Jia-Xi Mao, Fei Teng, Hang Yuan, Cong Liu, Hong Fu, Ke-Yan Sun, Guo-Shan Ding, Wen-Yuan Guo
No abstract text is available yet for this article.
December 6, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30611667/noninvasive-diagnosis-of-nonalcoholic-steatohepatitis-emerging-approaches
#18
EDITORIAL
Qin Pan, Jian-Gao Fan
No abstract text is available yet for this article.
February 2019: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30413347/biliary-leakage-following-pancreaticoduodenectomy-prevalence-risk-factors-and-management
#19
Ayman El Nakeeb, Mohamed El Sorogy, Hosam Hamed, Rami Said, Mohamad Elrefai, Helmy Ezzat, Waleed Askar, Ahmed M Elsabbagh
BACKGROUND: Few studies investigated biliary leakage after pancreaticoduodenectomy (PD) especially when compared to postoperative pancreatic fistula (POPF). This study was to determine the incidence of biliary leakage after PD, predisposing factors of biliary leakage, and its management. METHODS: We retrospectively studied all patients who underwent PD from January 2008 to December 2017 at Gastrointestinal Surgery Center, Mansoura University, Egypt. According to occurrence of postoperative biliary leakage, patients were divided into two groups...
February 2019: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/30420319/alpha-fetoprotein-screening-in-patients-with-hepatitis-c-induced-cirrhosis-who-achieved-a-sustained-virologic-response-in-the-direct-acting-antiviral-agents-era
#20
LETTER
Marco Spadaccini, Ana Lleo, Roberto Ceriani, Giovanni Covini, Lorenza Rimassa, Guido Torzilli, Luca Di Tommaso, Alessio Aghemo
No abstract text is available yet for this article.
December 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
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