Journals Nigerian Journal of Clinical P...

Nigerian Journal of Clinical Practice
C A Nri-Ezedi, T Ulasi, J Chukwuka, H Okpara, O Ofiaeli, E Nwaneli, A Ulasi
Background: Adiponectin is an excellent insulin sensitizer. It also possesses anti-inflammatory and anti-atherogenic properties that play a crucial role in the pathogenesis of cardio-metabolic disorders. Evaluating adiponectin distribution in children and factors that modulate its blood level is critical for advancing knowledge in its future role in managing associated non-communicable diseases. Aim: To investigate the adiponectin profile in apparently healthy pre-pubertal Nigerian school children...
June 2021: Nigerian Journal of Clinical Practice
S Wang, Q Zhang, H Wu, Z Yang, X Guo, F Wang, Z Yu, Z Zhong
Aims: The aim of the present study was to investigate mutation status of the cKit and PDGFRA genes in patients with a gastrointestinal stromal tumor (GIST). Methods: In total, 96 patients with a GIST were included in the study, in which polymerase chain reaction amplification and gene sequencing were used to detect the sequences of exons 9, 11, 12, 13, 14, 17, and 18 in KIT and exons 12, 14, and 18 in PDGFRA. Results: KIT mutations were detected in 65 cases (67...
June 2021: Nigerian Journal of Clinical Practice
M Alay, M Atmaca, R Ucler, M Aslan, I Seven, Y Dirik, M G Sonmez
Background: Mean platelet volume (MPV) is associated with cardiovascular morbidity and mortality in type 2 diabetic patients. However, the effects of blood glucose regulation and treatment regime on MPV has not been adequately studied in type 2 diabetic patients. Aims: We studied the effects of blood glucose regulation and treatment regimen on mean platelet volume in Type 2 diabetic patients. Subjects and Methods: A total of 232 diabetic patients who were admitted to the hospital in short intervals of 3 months in the last 2 years were included in the study...
June 2021: Nigerian Journal of Clinical Practice
Y N Jibril, K A Shamsu, N Bello Muhammad, M G Hasheem, A R Tukur, A D Salisu
Background: Cerebral palsy (CP) is a commonly occurring disorder of movement and posture that starts in early childhood. It is accompanied by other disturbances including hearing loss which has been shown to worsen the quality of life of the patients due to problems associated with speech and language acquisition. Several factors are responsible for developing hearing loss in CP. Aims: To determine the factors that can help in early diagnosis and treatment of hearing loss in children with cerebral palsy...
June 2021: Nigerian Journal of Clinical Practice
B S Kwan, S G Shim, D H Cho, K M Kim, I S Choi, D G Lee
Background: Hepatitis B virus (HBV) infection is a major global health problem, and healthcare workers (HCWs) are at high risk for HBV infection. Current guidelines strongly recommend immunization and screening for high-risk groups. Aims: We evaluated immunization and screening for HBV vaccination, assessed post-vaccination immune status of HCW's and characterized potential risk factors associated with poor immune response. Materials and Methods: From January 2010 to December 2018, we retrospectively analyzed comprehensive health checkup data for a total of 303 HCWs who received an HBV vaccination...
June 2021: Nigerian Journal of Clinical Practice
Erdogan Asar, Erdem Karabulut
Background: In dentistry, single-jaw surgery or double-jaw surgery is performed depending on the patient's need to correct severe skeletal malocclusions. The effect of these surgical methods used in treatment is to be investigated with quasi-least squares regression (QLS), which is a new data analysis method for correlated data obtained by extending generalized estimating equations (GEE). Aim: The aim of this study is to investigate whether jaw surgery methods (single jaw and double jaw) and time are effective on some outcome variables (C point menton distance, cervical plane angle, distance from point C to pogonion perpendicular, angle between cervical plane and facial plane) using QLS method...
June 2021: Nigerian Journal of Clinical Practice
F E Ogbetere
Testicular torsion leads to loss of blood supply to the testes due to the twisting of the spermatic cord and its contents, necessitating urgent surgical intervention to salvage the affected testis. Testicular loss from missed diagnosis and delayed referral is preventable, especially when patients present early to first contact health care workers. This makes having the correct diagnostic knowledge for testicular torsion by these first contact healthcare providers a very essential determinant of its overall outcome...
May 2021: Nigerian Journal of Clinical Practice
A O Jasper, E A Onohwakpor, A Akhator
Patients with high-risk conditions for surgery may benefit from some form of regional block when neuroaxial regional blocks may be life threatening. Despite the increased use of ultrasound-guided peripheral regional blocks internationally, local infiltration and targeted nerve blocks aided by knowledge of anatomical landmarks remain helpful in these two patients presented. A 48-year old woman, presented with bleeding left breast mass, mild respiratory distress, and radiological features of lung metastases (Carcinoma of the breast stage 4)...
May 2021: Nigerian Journal of Clinical Practice
O Jimoh, S Aliyu, J Ejembi, M M Abdulaziz, M Ibrahim, A Ibrahim, A T Olayinka
Gonorrhoea is a sexually transmitted infection (STI) that increases the risk of infection with human immunodeficiency virus (HIV) and causes infertility and urethral stricture. We describe three cases of sexually active men, otherwise stable, who presented with a history of painful micturition and creamy white, urethral discharge. A clinical diagnosis of gonococcal urethritis was made and confirmed by microscopy, culture and 16SrRNA. Antimicrobial susceptibility revealed resistance to all the antimicrobial agents tested including ceftriaxone...
May 2021: Nigerian Journal of Clinical Practice
M Yoldas, H Turk, T K Yoldas
Objective: To evaluate predictive clinical and histopathological risk factors for bladder cancer recurrence in patients who underwent nephroureterectomy for primary upper urinary tract transitional cell carcinoma (TCC). Subjects and Methods: Data of 111 patients, who were diagnosed with upper urinary tract TCC and underwent nephroureterectomy were reviewed A total of 65 patients were included in the study, after excluding 34 patients. Results: Bladder cancer recurrence developed in 20 (30...
May 2021: Nigerian Journal of Clinical Practice
S Gun, M Kefeli, L Yildiz
Objective: BRAF mutation is detected in 50-70% of melanomas. The molecular methods used to detect BRAF mutations are 80-90% sensitive, specific, and expensive methods. Immunohistochemistry is a relatively common, rapid, relatively inexpensive method in pathology practice compared to molecular techniques. Aims: We aimed to compare immunohistochemical and molecular methods in our case of malign melanoma in which we investigated BRAF mutation with "real time PCR" method and to investigate the compatibility of molecular test results of BRAF immunohistochemistry results as a preliminary test...
May 2021: Nigerian Journal of Clinical Practice
D D Shwe, T O Afolaranmi, C O Egbodo, J Musa, S Oguche, F Bode-Thomas
Background: Omphalitis is an important cause of neonatal sepsis (NNS) and mortality. Quantitative estimates of risk of omphalitis-related neonatal death is about 10%-19%. Topical applications of antiseptics have been shown to reduce this risk burden but has not been well investigated. Aim: To demonstrate non-inferiority of methylated spirit to chlorhexidine (CHX) gel for prevention of omphalitis, NNS and mortality at day 28. Methods: This was a randomized, non-inferiority trial of methylated spirit versus CHX gel with 161 and 162 mother-baby pairs, respectively, conducted between July 2017 and May 2018...
May 2021: Nigerian Journal of Clinical Practice
B Yilmaz, E Somay
Aims: We aimed to objectively assess the COVID-19 awareness of the patients requiring dental interventions in our dental clinic by utilizing a newly generated questionnaire, which may serve helpfully in the hard battle against the pandemic in our country. Materials and Methods: This study included 306 volunteer adults who applied to our dental clinic for dental interventions during the early days of COVID-19 outbreak in Turkey. All patients responded to a newly created questionnaire composed of four sections with 19 questions those mostly assessing the social and demographic details; like the participant's age, gender, marital status, education status, medical history, basic dental hygiene habits, occupation, and general information about the COVID-19 infection and its protection methods...
May 2021: Nigerian Journal of Clinical Practice
Afnan A Nassar
Background: The Saudi Ministry of Health (MOH) has published detailed guidelines and educational documents about Coronavirus disease 2019 (COVID-19) prevention and infection control. The knowledge of dentists of the reported guidelines is not yet assessed and lack of awareness of these guidelines may have negative implications on dental patients. Aims: The aim of this study is to assess the knowledge of dentists about COVID-19 and the MOH guidelines while treating dental patients in Saudi Arabia...
May 2021: Nigerian Journal of Clinical Practice
T Y Alhazzazi
Background: Widening the breadth of dentists' responsibilities to include screening all patients for life-threatening diseases, such as head and neck cancer (HNC), is crucial to improve survival rates and decrease morbidity. Aims: The study aimed to assess the knowledge and behavior of dentists toward screening and managing patients with HNC in Daudi Arabia. Thus, this study aimed to assess the knowledge and behavior of dentists toward screening and managing patients with HNC in Saudi Arabia...
May 2021: Nigerian Journal of Clinical Practice
H Kankaya, O Usta Yesilbalkan
Background: It is important to inform nursing students about stroke and improve their role in the clinic. Aims: We aimed to assess the awareness/knowledge of stroke risk factors and warning signs among nursing students. Therefore, we aimed to assess the awareness/knowledge of stroke risk factors and warning signs among nursing students. Materials and Methods: The descriptive and cross-sectional study was carried out between December 2017 and March 2018 with intern students at the faculty of nursing of a university...
May 2021: Nigerian Journal of Clinical Practice
U B Okafor, D T Goon
Background: Midwives have a strategic role to inform, educate, and encourage pregnant women to maintain an active lifestyle during pregnancy. Aim: This study explored a cohort of midwives' perspectives on providing prenatal physical activity education and counseling during pregnancy. Subjects and Methods: Seventeen midwives participated in semistructured interviews which were audio-recorded and transcribed verbatim. A thematic analysis approach was applied to the transcribed qualitative data...
May 2021: Nigerian Journal of Clinical Practice
O Osagie, B D Saheeb, E P Egbor
Aim: To compare the effects of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) on oral health-related quality of life (OHQoL) following impacted mandibular third molar (M3) surgery. Patients and Methods: A prospective, randomized study of 50 subjects was designed. Participants were divided equally into the PRP and PRF groups. The OHQoL was assessed using the OHQoL-UK instrument preoperatively and on postoperative days (PODS) 1, 3, and 7. Categorical variables were presented as frequencies and proportions...
May 2021: Nigerian Journal of Clinical Practice
A K Culhaoglu, M A Kilicarslan, B Gokdeniz, G Gur
Background: Using lasers for adhesive restoration removal can be practical and atraumatic. Aims: The purpose of this study was to investigate Er: YAG laser exposure on debonding the adhesive cementation between enamel and feldspar ceramic, lithium disilicate-reinforced and resin nano ceramic composite laminate restorations. Materials and Methods: Vita Cerec Blocs, IPS e.max Computer-aided design (CAD). Computer-aided design and manufacturing (CAD-CAM) in full and Lava Ultimate restorative materials were chosen...
May 2021: Nigerian Journal of Clinical Practice
E I Alshayea, K Almoammar, R M Feteih, I M Masoud, S F Albarakati
Objectives: This cross-sectional observational retrospective study aimed at assessing the cephalometric skeleto-dental features of class I, II, and III skeletal relationships of Saudi female school children samples and comparing the results to the established North American Caucasian cephalometric standards. Methods: The sample consisted of 205 retrospective lateral cephalometric radiographs of female school children. The age range of the subjects was between 10 and 13 years with a mean age of 11 ± 1 years...
May 2021: Nigerian Journal of Clinical Practice
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