Danielle Vienneau, Massimo Stafoggia, Sophia Rodopoulou, Jie Chen, Richard W Atkinson, Mariska Bauwelinck, Jochem O Klompmaker, Bente Oftedal, Zorana J Andersen, Nicole A H Janssen, Rina So, Youn-Hee Lim, Benjamin Flückiger, Regina Ducret-Stich, Martin Röösli, Nicole Probst-Hensch, Nino Künzli, Maciek Strak, Evangelia Samoli, Kees de Hoogh, Bert Brunekreef, Gerard Hoek
BACKGROUND: Long-term exposure to air pollution and noise is detrimental to health; but studies that evaluated both remain limited. This study explores associations with natural and cause-specific mortality for a range of air pollutants and transportation noise. METHODS: Over 4 million adults in Switzerland were followed from 2000 to 2014. Exposure to PM2.5 , PM2.5 components (Cu, Fe, S and Zn), NO2 , black carbon (BC) and ozone (O3 ) from European models, and transportation noise from source-specific Swiss models, were assigned at baseline home addresses...
March 27, 2023: Environmental Health
W Jay Christian, John Flunker, Beverly May, Susan Westneat, Wayne T Sanderson, Nancy Schoenberg, Steven R Browning
BACKGROUND: Appalachian Kentucky is a rural area with a high prevalence of asthma among adults. The relative contribution of environmental exposures in the etiology of adult asthma in these populations has been understudied. OBJECTIVE: This manuscript describes the aims, study design, methods, and characteristics of participants for the Mountain Air Project (MAP), and focuses on associations between small area environmental exposures, including roadways and mining operations, and lifetime and current asthma in adults...
March 27, 2023: Environmental Health
Manuela Campisi, Giuseppe Mastrangelo, Danuta Mielżyńska-Švach, Mirjam Hoxha, Valentina Bollati, Andrea A Baccarelli, Angela Carta, Stefano Porru, Sofia Pavanello
BACKGROUND: Aging represents a serious health and socioeconomic concern for our society. However, not all people age in the same way and air pollution has been shown to largely impact this process. We explored whether polycyclic aromatic hydrocarbons (PAHs), excellent fossil and wood burning tracers, accelerate biological aging detected by lymphocytes DNA methylation age (DNAmAge) and telomere length (TL), early nuclear DNA (nDNA) hallmarks of non-mitotic and mitotic cellular aging, and mitochondrial DNA copy number (mtDNAcn)...
March 17, 2023: Environmental Health
Marcel Miron-Celis, Robert Talarico, Paul J Villeneuve, Eric Crighton, David M Stieb, Cristina Stanescu, Éric Lavigne
BACKGROUND: Ambient air pollution has been associated with gestational diabetes (GD), but critical windows of exposure and whether maternal pre-existing conditions and other environmental factors modify the associations remains inconclusive. METHODS: We conducted a retrospective cohort study of all singleton live birth that occurred between April 1st 2006 and March 31st 2018 in Ontario, Canada. Ambient air pollution data (i.e., fine particulate matter with a diameter ≤ 2...
March 15, 2023: Environmental Health
Mercè Garí, Rebecca Moos, Daniel Bury, Monika Kasper-Sonnenberg, Agnieszka Jankowska, Aleksandra Andysz, Wojciech Hanke, Dennis Nowak, Stephan Bose-O'Reilly, Holger M Koch, Kinga Polańska
No abstract text is available yet for this article.
March 13, 2023: Environmental Health
Alexander Hedbrant, Christopher Engström, Lena Andersson, Daniel Eklund, Håkan Westberg, Alexander Persson, Eva Särndahl
BACKGROUND: The inflammatory responses are central components of diseases associated with particulate matter (PM) exposure, including systemic diseases such as cardiovascular diseases (CVDs). The aim of this study was to determine if exposure to PM, including respirable dust or quartz in the iron foundry environment mediates systemic inflammatory responses, focusing on the NLRP3 inflammasome and novel or established inflammatory markers of CVDs. METHODS: The exposure to PM, including respirable dust, metals and quartz were determined in 40 foundry workers at two separate occasions per worker...
March 13, 2023: Environmental Health
Changpeng Liu, Dongjian Yang, Yuxi Liu, Heng Piao, Tao Zhang, Xi Li, Erjiang Zhao, Di Zhang, Yan Zheng, Xiance Tang
Exposure to fine particulate matter (PM2.5 ) is linked to lung cancer incidence and mortality. However, the impact of PM2.5 exposure on lung cancer patients after lobectomy, which remains the primary treatment for early-stage lung cancer, is unknown. Therefore, we investigated the correlation between PM2.5 exposure and the survival of lung cancer patients after lobectomy. This study included 3,327 patients with lung cancer who underwent lobectomy procedures. We converted residential addresses into coordinates and estimated individual patients' daily PM2...
March 7, 2023: Environmental Health
Frida Soesanti, Cuno S P M Uiterwaal, Kees Meliefste, Jie Chen, Bert Brunekreef, Nikmah S Idris, Diederick E Grobbee, Kerstin Klipstein-Grobusch, Gerard Hoek
BACKGROUND: Ambient air pollution has been recognized as one of the most important environmental health threats. Exposure in early life may affect pregnancy outcomes and the health of the offspring. The main objective of our study was to assess the association between prenatal exposure to traffic related air pollutants during pregnancy on birth weight and length. Second, to evaluate the association between prenatal exposure to traffic related air pollutants and the risk of low birth weight (LBW)...
February 27, 2023: Environmental Health
Youssef Oulhote, Florence Rouget, Léah Michineau, Christine Monfort, Mireille Desrochers-Couture, Jean-Pierre Thomé, Philippe Kadhel, Luc Multigner, Sylvaine Cordier, Gina Muckle
BACKGROUND: Chlordecone is a highly persistent organochlorine insecticide that was intensively used in banana fields in the French West Indies, resulting in a widespread contamination. Neurotoxicity of acute exposures in adults is well recognized, and empirical data suggests that prenatal exposure affects visual and fine motor developments during infancy and childhood, with greater susceptibility in boys. OBJECTIVE: To assess the associations between pre- and postnatal exposures to chlordecone and cognitive and behavioral functions in school-aged children from Guadeloupe...
February 27, 2023: Environmental Health
Philip Crepeau, Zhenyu Zhang, Rhea Udyavar, Lilah Morris-Wiseman, Shyam Biswal, Murugappan Ramanathan, Aarti Mathur
BACKGROUND: Limited data exists suggesting that cumulative exposure to air pollution in the form of fine particulate matter (aerodynamic diameter ≤ 2.5 μm [PM2.5 ]) may be associated with papillary thyroid carcinoma (PTC), although this relationship has not been widely established. This study aims to evaluate the association between PM2.5 and PTC and determine the subgroups of patients who are at the highest risk of PTC diagnosis. METHODS: Under IRB approval, we conducted a case-control study of adult patients (age ≥ 18) newly diagnosed with PTC between 1/2013-12/2016 across a single health care system were identified using electronic medical records...
February 23, 2023: Environmental Health
Veronika Ehrlich, Wieneke Bil, Rob Vandebriel, Berit Granum, Mirjam Luijten, Birgitte Lindeman, Philippe Grandjean, Andreas-Marius Kaiser, Ingrid Hauzenberger, Christina Hartmann, Claudia Gundacker, Maria Uhl
BACKGROUND: Per- and polyfluoroalkyl substances (PFAS) are of public health concern, because of their ubiquitous and extremely persistent occurrence, and depending on their structure, their bio-accumulative, mobile and toxic properties. Human health effects associated with exposure to PFAS include adverse effects on the immune system. In 2020, EFSA (the European Food Safety Authority) defined adverse effects on the immune system as the most critical effect for human health risk assessment, based on reduced antibody responses to childhood vaccines and similar effects observed in experimental animal studies...
February 22, 2023: Environmental Health
Enora Cléro, Claire Demoury, Bernd Grosche, Liudmila Liutsko, Yvon Motreff, Takashi Ohba, Deborah Oughton, Philippe Pirard, Agnès Rogel, Thierry Schneider, An Van Nieuwenhuyse, Dominique Laurier, Elisabeth Cardis
BACKGROUND: The SHAMISEN (Nuclear Emergency Situations - Improvement of Medical And Health Surveillance) European project was conducted in 2015-2017 to review the lessons learned from the experience of past nuclear accidents and develop recommendations for preparedness and health surveillance of populations affected by a nuclear accident. Using a toolkit approach, Tsuda et al. recently published a critical review of the article by Cléro et al. derived from the SHAMISEN project on thyroid cancer screening after nuclear accident...
February 17, 2023: Environmental Health
M N S Figaroa, M Gielen, L Casas, R J F Loos, C Derom, S Weyers, T S Nawrot, M P Zeegers, E M Bijnens
BACKGROUND: Globally, the rapid increase of obesity is reaching alarming proportions. A new approach to reduce obesity and its comorbidities involves tackling the built environment. Environmental influences seem to play an important role, but the environmental influences in early life on adult body composition have not been thoroughly investigated. This study seeks to fill the research gap by examining early-life exposure to residential green spaces and traffic exposure in association with body composition among a population of young adult twins...
February 17, 2023: Environmental Health
Xiaoli Shen, Xia Meng, Cuiping Wang, Xiangfeng Chen, Qian Chen, Jing Cai, Jun Zhang, Qianlong Zhang, Lichun Fan
BACKGROUND: Considerable attention has been paid to reproductive toxicity of fine particulate matter (PM2.5 ). However, the relationship between prenatal PM2.5 exposure and anogenital distance (AGD) has not been well studied. We aim to investigate the potential effects of prenatal exposure to PM2.5 on newborn AGD. METHODS: Prenatal PM2.5 exposure of 2332 participates in Shanghai (2013-2016) was estimated using high-performance machine learning models. Anoscrotal distance (AGDas) in male infants and anofourchette distance (AGDaf) in female infants were measured by well-trained examiners within 3 days after birth...
February 9, 2023: Environmental Health
Annelise Blomberg, Jann Mortensen, Pal Weihe, Philippe Grandjean
No abstract text is available yet for this article.
January 30, 2023: Environmental Health
Xiang Zeng, Ge Tian, Jingfang Zhu, Fuyun Yang, Rui Zhang, Huijun Li, Zhen An, Juan Li, Jie Song, Jing Jiang, Dongling Liu, Weidong Wu
Epidemiological evidence has linked air pollution with adverse respiratory outcomes, but the mechanisms underlying susceptibility to air pollution remain unclear. This study aimed to investigate the role of glutathione S-transferase (GST) polymorphism in the association between air pollution and lung function levels. A total of 75 healthy young volunteers aged 18-20 years old were recruited for six follow-up visits and examinations. Spirometry was conducted to obtain lung function parameters such as forced vital capacity (FVC), and forced expiratory volume in 1 s (FEV1 )...
January 27, 2023: Environmental Health
Joachim Schüz, Evgenia Ostroumova, Ausrele Kesminiene, Louise Davies, Hyeong Sik Ahn, Kayo Togawa, Salvatore Vaccarella
BACKGROUND: Using a toolkit approach, Tsuda et al. critiqued work carried out by or in collaboration with the International Agency for Research on Cancer (IARC/WHO), including the IARC technical publication No. 46 on "Thyroid health monitoring after nuclear accidents" (TM-NUC), the project on nuclear emergency situations and improvement on medical and health surveillance (SHAMISEN), and the IARC-led work on global thyroid cancer incidence patterns as per IARC core mandate. MAIN BODY: We respond on the criticism of the recommendations of the IARC technical publication No...
January 26, 2023: Environmental Health
Hristina Denic-Roberts, Lawrence S Engel, Jeanine M Buchanich, Rachel G Miller, Evelyn O Talbott, Dana L Thomas, Glen A Cook, Tina Costacou, Jennifer A Rusiecki
BACKGROUND: Long-term neurological health risks associated with oil spill cleanup exposures are largely unknown. We aimed to investigate risks of longer-term neurological conditions among U.S. Coast Guard (USCG) responders to the 2010 Deepwater Horizon (DWH) oil spill. METHODS: We used data from active duty members of the DWH Oil Spill Coast Guard Cohort Study (N=45224). Self-reported oil spill exposures were ascertained from post-deployment surveys. Incident neurological outcomes were classified using International Classification of Diseases, 9th Revision, codes from military health encounter records up to 5...
January 25, 2023: Environmental Health
Zachariah E M Morgan, Maximilian J Bailey, Diana I Trifonova, Noopur C Naik, William B Patterson, Frederick W Lurmann, Howard H Chang, Bradley S Peterson, Michael I Goran, Tanya L Alderete
BACKGROUND: Higher prenatal ambient air pollution exposure has been associated with impaired neurodevelopment in preschoolers and school-aged children. The purpose of this study was to explore the relationships between prenatal ambient air pollution exposure and neurodevelopment during infancy. METHODS: This study examined 161 Latino mother-infant pairs from the Southern California Mother's Milk Study. Exposure assessments included prenatal nitrogen dioxide (NO2 ) and particulate matter smaller than 2...
January 24, 2023: Environmental Health
Jodie R Gawryluk, Daniela J Palombo, Jason Curran, Ashleigh Parker, Chris Carlsten
No abstract text is available yet for this article.
January 23, 2023: Environmental Health
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