journal
MENU ▼
Read by QxMD icon Read
search

Hormones: International Journal of Endocrinology and Metabolism

journal
https://read.qxmd.com/read/31087283/a-novel-fgf8-mutation-in-a-female-patient-with-isolated-congenital-anosmia
#1
LETTER
M I Stamou, L Plummer, V Koika, A Galli-Tsinopoulou, N A Georgopoulos
No abstract text is available yet for this article.
May 13, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31030405/non-functioning-pituitary-macroadenoma-surgical-outcomes-tumor-regrowth-and-alterations-in-pituitary-function-3-year-experience-from-the-iranian-pituitary-tumor-registry
#2
Atousa Najmaldin, Mojtaba Malek, Nahid Hashemi Madani, Mohammad Ghorbani, Hamideh Akbari, Alireza Khajavi, Omolbanin Asadi Qadikolaei, Mohammad Ebrahim Khamseh
PURPOSE: The aim of this study was to assess clinical features and therapeutic outcomes in patients with clinically non-functioning pituitary macroadenomas (NFPMAs). METHOD: This is a retrospective cohort study of NFPMA patients treated surgically and followed periodically between 2015 and 2017 in a tertiary care center in Iran. Descriptive analysis was performed applying appropriate tests. Binary logistic regression models were used to determine the predictive factors for subtotal tumor resection (STR) and hormonal recovery...
April 27, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30989578/-68-ga-psma-pet-thyroid-incidentalomas
#3
REVIEW
Francesco Bertagna, Domenico Albano, Luca Giovanella, Mattia Bonacina, Rexhep Durmo, Raffaele Giubbini, Giorgio Treglia
INTRODUCTION: Thyroid incidentaloma is defined as a thyroid lesion incidentally and newly detected by imaging techniques performed for an unrelated purpose and especially for a non-thyroid disease. The aim of this review is to evaluate the prevalence and clinical significance of focal incidental radiolabelled prostate-specific membrane antigen (PSMA) uptake in the thyroid gland [PSMA thyroid incidentaloma (PTI)] revealed by PET/CT or PET/MRI. METHODS: A comprehensive literature search of the PubMed/MEDLINE, Scopus, and Embase databases was conducted to find relevant published articles about the prevalence and clinical significance of PTIs detected by PET/CT or PET/MRI in patients studied for other oncologic purposes...
April 15, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30980254/selective-antagonism-of-crf1-receptor-by-a-substituted-pyrimidine
#4
Stelios Sakellaris, Minos-Timotheos Matsoukas, Vlasios Karageorgos, Smaragda Poulaki, Bhimanna Kuppast, Andrew Margioris, Maria Venihaki, Hesham Fahmy, George Liapakis
The corticotrophin-releasing factor (CRF) and its type 1 receptor (CRF1 R) regulate the hypothalamic-pituitary-adrenal axis, as well as other systems, thus playing a crucial role in the maintenance of homeostasis. Non-peptide CRF1 R-selective antagonists exert therapeutic effects on experimental animals with abnormal regulation of their homeostatic mechanisms. However, none of them is as yet in clinical use. In an effort to develop novel small non-peptide CRF1 R-selective antagonists, we have synthesized a series of substituted pyrimidines described in a previous study...
April 12, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30905030/challenges-in-the-treatment-of-parathyroid-carcinoma-a-case-report
#5
REVIEW
Marco Russo, Graziella Borzì, Marturano Ilenia, Francesco Frasca, Pasqualino Malandrino, Damiano Gullo
INTRODUCTION: Parathyroid carcinoma (PC) is a rare neoplasm with a high rate of recurrence and an indolent course. It is frequently functional, causing nearly 1% of the cases of primary hyperparathyroidism (HPT), and in some cases, it may be complicated by brown tumors, mimicking bone metastases. Synchronous parathyroid and papillary thyroid carcinomas are rare. CASE REPORT: We present a patient with HPT due to PC, misdiagnosed at first evaluation, which exhibited multiple hypermetabolic lytic lesions in the skeleton, suggesting bone metastases...
March 23, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30900216/decreased-circulating-levels-of-angptl8-in-graves-disease-patients
#6
Haoxiang Li, Mengjiao Xu, Li Zhao, Hong Xia, Yanyan Li, Xiafei Hong, Xia Deng, Jing Yuan, Yi Ding, Chang Guo, Ruirong Pan, Dong Wang, Jifang Wang, Wei Yin, Ling Yang, Guoyue Yuan
BACKGROUND: Angiopoietin-like protein 8 (ANGPTL8), a newly identified hormone, has been recently characterized as a metabolic regulator which can affect energy homeostasis and has interesting potentials as a metabolic disease therapy. However, little is as yet known as to whether circulating ANGPTL8 levels are altered in thyroid dysfunction. This study measured serum ANGPTL8 levels in patients with Graves' disease and explored the correlations between its serum levels and thyroid index in Graves' disease...
March 21, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30859430/correction-to-conducting-an-observational-study-during-an-economic-crisis-analysis-of-the-treatment-and-follow-up-phase-of-greek-patients-participating-in-the-exfos-study
#7
Kyriakos Aloumanis, G Kapetanos, T Alexandridis, V Drossinos, N Papaioannou
Unfortunately in the original publication, the affiliation of the author N. Papaioannou was incorrectly provided.
March 11, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30840230/from-gut-microbiota-dysfunction-to-obesity-could-short-chain-fatty-acids-stop-this-dangerous-course
#8
REVIEW
Luigi Barrea, Giovanna Muscogiuri, Giuseppe Annunziata, Daniela Laudisio, Gabriella Pugliese, Ciro Salzano, Annamaria Colao, Silvia Savastano
Study of the interactions between the gut microbiota and brain-gut axis represents a very appealing approach to increasing our knowledge about the mechanisms leading to obesity and obesity-related diseases. The aim of this review is to focus on the effects of short-chain fatty acids (SCFAs), which are the main products of gut microbial fermentation from non-digestible carbohydrates in the colon, on the gut-brain axis. Evidence is accumulating regarding the role of SCFAs in the fine-tuning of the gut-brain axis, a feedback system which is vital not only for the proper maintenance of gastrointestinal and metabolic functions, but also for the regulation of food intake and energy expenditure...
March 6, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30835061/mona-lisa-is-euthyroid-a-modern-day-diagnosis
#9
Michael Yafi
Making any medical diagnosis of an individual appearing in an old painting is risky. Throughout history, the famous painting of the Mona Lisa by Leonardo da Vinci has challenged many scientists and physicians to scrutinize this striking and enigmatic female image for the purpose of potentially explaining the woman "behind the smile" and offering a medical diagnosis of her state of health. A recent proposal was that she suffered from severe hypothyroidism and that her asymmetric smile was due to psychomotor retardation...
March 5, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30827017/the-effects-of-acarbose-on-chemokine-and-cytokine-production-in-human-monocytic-thp-1-cells
#10
Yi-Ching Lin, Yen-Chun Chen, Hui-Pin Hsiao, Chang-Hung Kuo, Bai-Hsiun Chen, Yi-Ting Chen, Shih-Ling Wang, Mei-Lan Tsai, Chih-Hsing Hung
BACKGROUND AND OBJECTIVES: Chronic inflammation induced by proinflammatory cytokines and chemokines is postulated to be involved in insulin resistance and β-cell dysfunction in type 2 diabetes mellitus (T2DM). Acarbose, the α-glucosidase inhibitor, is an oral antidiabetic drug for T2DM. Acarbose suppresses inflammatory cytokine production in patients with T2DM, though the underlying mechanisms are unclear. In the present study, we aimed to investigate the anti-inflammatory effects and the exact mechanisms of acarbose in human monocytic THP-1 cells...
March 2, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30827016/reviews-based-on-1st-mediterranean-experts-meeting-on-the-topic-vitamin-d-in-the-prevention-of-health-disparities-during-adult-life
#11
EDITORIAL
Kalliopi Kotsa, Spyridon Karras, Pantelis Zembekakis
No abstract text is available yet for this article.
March 2, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30644069/patient-empowerment-and-the-mediterranean-diet-as-a-possible-tool-to-tackle-prediabetes-associated-with-overweight-or-obesity-a-pilot-study
#12
Giovanna Muscogiuri, Luigi Barrea, Carolina Di Somma, Barbara Altieri, Martina Vecchiarini, Francesco Orio, Tiziana Spinosa, Annamaria Colao, Silvia Savastano
AIM: The objective of this study was to investigate the effect of implementation of short-term patient empowerment as applied to Mediterranean diet (MD) adherence on metabolic and anthropometric parameters in prediabetic overweight or obese subjects. METHODS: The sample included 42 subjects with prediabetes, aged 18-75 years and with body mass index (BMI) > 25 kg/m2 , who received dietary advice on MD by nutritionists during session groups every 2 weeks for 4 months...
March 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/29876797/hypoparathyroidism-is-it-that-easy-to-treat
#13
REVIEW
Evangelia Triantafyllou, Maria P Yavropoulou, Athanasios D Anastasilakis, Polyzois Makras
Hypoparathyroidism is a relatively rare endocrine disease characterised by either null or inappropriately low secretion of parathyroid hormone (PTH) for serum calcium levels. The other main laboratory findings include hypocalcaemia, inappropriately normal or high urine calcium excretion and hyperphosphataemia with low urine phosphate excretion. The management of hypoparathyroidism should be tailored to each individual case, which makes it a demanding undertaking in everyday clinical practice. In this review, we sought to focus on the diagnostic approach of hypoparathyroidism and the therapeutic challenges of the disease from a clinical perspective...
March 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/29858842/functional-hypothalamic-amenorrhea-case-presentations-and-overview-of-literature
#14
REVIEW
Shahla Nader
Functional hypothalamic amenorrhea is a form of chronic anovulation not due to identifiable organic causes with adverse health consequences. A thorough history is paramount in the identification of women with this disorder as it is usually associated with lifestyle factors such as stress, weight loss, and excessive exercise. In this paper, recently published clinical guidelines are reviewed and a series of cases is presented that highlights diagnostic and therapeutic challenges encountered.
March 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30805908/clinical-validation-of-a-non-invasive-electrodermal-biofeedback-device-useful-for-reducing-chronic-perceived-pain-and-systemic-inflammation
#15
George P Chrousos, Dario Boschiero
BACKGROUND: This study was performed to evaluate the potential clinical usefulness of a new non-invasive electrodermal biofeedback device in reducing perceived pain levels and chronic systemic inflammation. MATERIALS AND METHODS: This multicenter study was designed and coordinated by BioTekna, included 20 general practice medical centers, took place between June 2010 and January 2011, and was validated clinically at the National and Kapodistrian University of Athens, Greece...
February 25, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30805907/correction-to-transsphenoidal-surgery-for-pituitary-adenomas-early-results-from-a-single-center
#16
I Karamouzis, M Caputo, C Mele, A Nuzzo, M Zavattaro, P Car, G Panzarasa, F Prodam, P Marzullo, Gianluca Aimaretti
Unfortunately in the original publication, the affiliation of the author Paolo Marzullo was incorrect. The author inadvertently missed out to include his second affiliation.
February 25, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30778850/a-toddler-with-a-novel-lepr-mutation
#17
REVIEW
Coşkun Armağan, Ceren Yılmaz, Altuğ Koç, Ayhan Abacı, Ayfer Ülgenalp, Ece Böber, Derya Erçal, Korcan Demir
There are numerous causes, such as environmental factors, medications, endocrine disorders, and genetic factors, that can lead to obesity. However, severe early-onset obesity with abnormal feeding behavior, mental retardation, dysmorphic features, organ-specific developmental abnormalities, and endocrine disorders suggest a genetic etiology. Mutations in genes related to the leptin-melanocortin pathway play a key role in genetic obesity. This pathway controls hypothalamic regulation of food intake. A few cases have been reported to have mutations in leptin (LEP) or leptin receptor (LEPR) genes...
February 18, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30747412/a-novel-thyroid-hormone-receptor-alpha-gene-mutation-clinic-characteristics-and-follow-up-findings-in-a-patient-with-thyroid-hormone-resistance
#18
REVIEW
Ozlem Korkmaz, Samim Ozen, Taha Resid Ozdemir, Damla Goksen, Sukran Darcan
Thyroid hormone receptor alpha (THRA) gene mutation is a thyroid hormone resistance syndrome characterized by near-normal thyroid function tests and tissue-specific hypothyroidism. In this case study, we report a novel de novo p.G291S heterozygous mutation in the THRA gene was detected at mutation analysis. A 4-year-old male patient was admitted due to short stature, motor-mental retardation, and constipation. At physical examination, coarse facial appearance, eyelid edema, pallor, and umbilical hernia were observed...
February 12, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30747411/evaluation-of-growth-and-puberty-in-a-child-with-a-novel-tbx19-gene-mutation-and-review-of-the-literature
#19
REVIEW
Zehra Yavas Abali, Gozde Yesil, Tarik Kirkgoz, Sare Betul Kaygusuz, Mehmet Eltan, Serap Turan, Abdullah Bereket, Tulay Guran
BACKGROUND: Biallelic mutations in the TBX19 gene cause severe early-onset adrenal failure due to isolated ACTH deficiency (IAD). This rare disease is characterized by low plasma ACTH and cortisol levels, with normal secretion of other pituitary hormones. Herein, we report a patient with IAD due to a novel TBX19 gene mutation, who is also of tall stature. CASE REPORT: A 48/12 -year-old girl was presented with loss of consciousness due to hypoglycemia. The patient was born at term with a birth weight of 3800 g...
February 12, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30737657/patients-with-extra-adrenal-malignancies-and-adrenal-lesions-have-similar-rates-of-subclinical-hypercortisolism-compared-with-patients-with-true-adrenal-incidentalomas
#20
Alexandra Chrisoulidou, Pantelitsa Rakitzi, Maria Boudina, Fani Apostolidou-Kiouti, Eirini Poimenidou, Achilleas Papanikolaou, Anastasia Devlioti, Grigorios Rallis, Kalliopi Pazaitou-Panayiotou
OBJECTIVE: During follow-up in cancer patients, adrenal lesions are frequently found by computer tomography imaging. In these patients, the frequency of subclinical Cushing's syndrome (SCS) has not been fully explored. The aim of the present study was to investigate the presence of SCS in cancer patients with adrenal lesions in comparison to patients with true adrenal incidentalomas. DESIGN: We studied 95 patients with adrenal lesions: 57 patients (group A, 20 males and 37 females) had a history of extra-adrenal malignancy and adrenal lesions were discovered during staging of the primary cancer, and 38 patients (group B, 6 males and 32 females) had adrenal incidentalomas...
February 9, 2019: Hormones: International Journal of Endocrinology and Metabolism
journal
journal
40161
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"