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Hormones: International Journal of Endocrinology and Metabolism

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https://read.qxmd.com/read/30859430/correction-to-conducting-an-observational-study-during-an-economic-crisis-analysis-of-the-treatment-and-follow-up-phase-of-greek-patients-participating-in-the-exfos-study
#1
Kyriakos Aloumanis, G Kapetanos, T Alexandridis, V Drossinos, N Papaioannou
Unfortunately in the original publication, the affiliation of the author N. Papaioannou was incorrectly provided.
March 11, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30840230/from-gut-microbiota-dysfunction-to-obesity-could-short-chain-fatty-acids-stop-this-dangerous-course
#2
REVIEW
Luigi Barrea, Giovanna Muscogiuri, Giuseppe Annunziata, Daniela Laudisio, Gabriella Pugliese, Ciro Salzano, Annamaria Colao, Silvia Savastano
Study of the interactions between the gut microbiota and brain-gut axis represents a very appealing approach to increasing our knowledge about the mechanisms leading to obesity and obesity-related diseases. The aim of this review is to focus on the effects of short-chain fatty acids (SCFAs), which are the main products of gut microbial fermentation from non-digestible carbohydrates in the colon, on the gut-brain axis. Evidence is accumulating regarding the role of SCFAs in the fine-tuning of the gut-brain axis, a feedback system which is vital not only for the proper maintenance of gastrointestinal and metabolic functions, but also for the regulation of food intake and energy expenditure...
March 6, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30835061/mona-lisa-is-euthyroid-a-modern-day-diagnosis
#3
Michael Yafi
Making any medical diagnosis of an individual appearing in an old painting is risky. Throughout history, the famous painting of the Mona Lisa by Leonardo da Vinci has challenged many scientists and physicians to scrutinize this striking and enigmatic female image for the purpose of potentially explaining the woman "behind the smile" and offering a medical diagnosis of her state of health. A recent proposal was that she suffered from severe hypothyroidism and that her asymmetric smile was due to psychomotor retardation...
March 5, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30827017/the-effects-of-acarbose-on-chemokine-and-cytokine-production-in-human-monocytic-thp-1-cells
#4
Yi-Ching Lin, Yen-Chun Chen, Hui-Pin Hsiao, Chang-Hung Kuo, Bai-Hsiun Chen, Yi-Ting Chen, Shih-Ling Wang, Mei-Lan Tsai, Chih-Hsing Hung
BACKGROUND AND OBJECTIVES: Chronic inflammation induced by proinflammatory cytokines and chemokines is postulated to be involved in insulin resistance and β-cell dysfunction in type 2 diabetes mellitus (T2DM). Acarbose, the α-glucosidase inhibitor, is an oral antidiabetic drug for T2DM. Acarbose suppresses inflammatory cytokine production in patients with T2DM, though the underlying mechanisms are unclear. In the present study, we aimed to investigate the anti-inflammatory effects and the exact mechanisms of acarbose in human monocytic THP-1 cells...
March 2, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30827016/reviews-based-on-1st-mediterranean-experts-meeting-on-the-topic-vitamin-d-in-the-prevention-of-health-disparities-during-adult-life
#5
EDITORIAL
Kalliopi Kotsa, Spyridon Karras, Pantelis Zembekakis
No abstract text is available yet for this article.
March 2, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30805908/clinical-validation-of-a-non-invasive-electrodermal-biofeedback-device-useful-for-reducing-chronic-perceived-pain-and-systemic-inflammation
#6
George P Chrousos, Dario Boschiero
BACKGROUND: This study was performed to evaluate the potential clinical usefulness of a new non-invasive electrodermal biofeedback device in reducing perceived pain levels and chronic systemic inflammation. MATERIALS AND METHODS: This multicenter study was designed and coordinated by BioTekna, included 20 general practice medical centers, took place between June 2010 and January 2011, and was validated clinically at the National and Kapodistrian University of Athens, Greece...
February 25, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30805907/correction-to-transsphenoidal-surgery-for-pituitary-adenomas-early-results-from-a-single-center
#7
I Karamouzis, M Caputo, C Mele, A Nuzzo, M Zavattaro, P Car, G Panzarasa, F Prodam, P Marzullo, Gianluca Aimaretti
Unfortunately in the original publication, the affiliation of the author Paolo Marzullo was incorrect. The author inadvertently missed out to include his second affiliation.
February 25, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30778850/a-toddler-with-a-novel-lepr-mutation
#8
REVIEW
Coşkun Armağan, Ceren Yılmaz, Altuğ Koç, Ayhan Abacı, Ayfer Ülgenalp, Ece Böber, Derya Erçal, Korcan Demir
There are numerous causes, such as environmental factors, medications, endocrine disorders, and genetic factors, that can lead to obesity. However, severe early-onset obesity with abnormal feeding behavior, mental retardation, dysmorphic features, organ-specific developmental abnormalities, and endocrine disorders suggest a genetic etiology. Mutations in genes related to the leptin-melanocortin pathway play a key role in genetic obesity. This pathway controls hypothalamic regulation of food intake. A few cases have been reported to have mutations in leptin (LEP) or leptin receptor (LEPR) genes...
February 18, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30747412/a-novel-thyroid-hormone-receptor-alpha-gene-mutation-clinic-characteristics-and-follow-up-findings-in-a-patient-with-thyroid-hormone-resistance
#9
REVIEW
Ozlem Korkmaz, Samim Ozen, Taha Resid Ozdemir, Damla Goksen, Sukran Darcan
Thyroid hormone receptor alpha (THRA) gene mutation is a thyroid hormone resistance syndrome characterized by near-normal thyroid function tests and tissue-specific hypothyroidism. In this case study, we report a novel de novo p.G291S heterozygous mutation in the THRA gene was detected at mutation analysis. A 4-year-old male patient was admitted due to short stature, motor-mental retardation, and constipation. At physical examination, coarse facial appearance, eyelid edema, pallor, and umbilical hernia were observed...
February 12, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30747411/evaluation-of-growth-and-puberty-in-a-child-with-a-novel-tbx19-gene-mutation-and-review-of-the-literature
#10
REVIEW
Zehra Yavas Abali, Gozde Yesil, Tarik Kirkgoz, Sare Betul Kaygusuz, Mehmet Eltan, Serap Turan, Abdullah Bereket, Tulay Guran
BACKGROUND: Biallelic mutations in the TBX19 gene cause severe early-onset adrenal failure due to isolated ACTH deficiency (IAD). This rare disease is characterized by low plasma ACTH and cortisol levels, with normal secretion of other pituitary hormones. Herein, we report a patient with IAD due to a novel TBX19 gene mutation, who is also of tall stature. CASE REPORT: A 48/12 -year-old girl was presented with loss of consciousness due to hypoglycemia. The patient was born at term with a birth weight of 3800 g...
February 12, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30737657/patients-with-extra-adrenal-malignancies-and-adrenal-lesions-have-similar-rates-of-subclinical-hypercortisolism-compared-with-patients-with-true-adrenal-incidentalomas
#11
Alexandra Chrisoulidou, Pantelitsa Rakitzi, Maria Boudina, Fani Apostolidou-Kiouti, Eirini Poimenidou, Achilleas Papanikolaou, Anastasia Devlioti, Grigorios Rallis, Kalliopi Pazaitou-Panayiotou
OBJECTIVE: During follow-up in cancer patients, adrenal lesions are frequently found by computer tomography imaging. In these patients, the frequency of subclinical Cushing's syndrome (SCS) has not been fully explored. The aim of the present study was to investigate the presence of SCS in cancer patients with adrenal lesions in comparison to patients with true adrenal incidentalomas. DESIGN: We studied 95 patients with adrenal lesions: 57 patients (group A, 20 males and 37 females) had a history of extra-adrenal malignancy and adrenal lesions were discovered during staging of the primary cancer, and 38 patients (group B, 6 males and 32 females) had adrenal incidentalomas...
February 9, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30719628/metformin-and-gut-microbiota-their-interactions-and-their-impact-on-diabetes
#12
REVIEW
Natalia G Vallianou, Theodora Stratigou, Stylianos Tsagarakis
The ratio of human to bacterial cells in the human body (microbiota) is around 1:1. As a result of co-evolution of the host mucosal immune system and the microbiota, both have developed multiple mechanisms to maintain homeostasis. However, dissociations between the composition of the gut microbiota and the human host may play a crucial role in the development of type 2 diabetes. Metformin, the most frequently administered medication to treat patients with type 2 diabetes, has only recently been suggested to alter gut microbiota composition through the increase in mucin-degrading Akkermansia muciniphila, as well as several SCFA-producing (short-chain fatty acid) microbiota...
February 4, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30644069/patient-empowerment-and-the-mediterranean-diet-as-a-possible-tool-to-tackle-prediabetes-associated-with-overweight-or-obesity-a-pilot-study
#13
Giovanna Muscogiuri, Luigi Barrea, Carolina Di Somma, Barbara Altieri, Martina Vecchiarini, Francesco Orio, Tiziana Spinosa, Annamaria Colao, Silvia Savastano
AIM: The objective of this study was to investigate the effect of implementation of short-term patient empowerment as applied to Mediterranean diet (MD) adherence on metabolic and anthropometric parameters in prediabetic overweight or obese subjects. METHODS: The sample included 42 subjects with prediabetes, aged 18-75 years and with body mass index (BMI) > 25 kg/m2 , who received dietary advice on MD by nutritionists during session groups every 2 weeks for 4 months...
January 14, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30612286/triple-a-syndrome-two-siblings-with-a-novel-mutation-in-the-aaas-gene
#14
REVIEW
Athanasia Bouliari, Xuexin Lu, Rebecca W Persky, Constantine A Stratakis
OBJECTIVE: Triple A syndrome is a rare autosomal recessive disorder caused by mutations in the AAAS gene on chromosome 12q13. Its main clinical features are alacrima, achalasia, and adrenal insufficiency, with most patients also having neurological symptoms and autonomic dysfunction. The neurologic manifestations are less well-understood, especially in children. Here, we examine two siblings who were found to have a novel mutation in the AAAS gene and who were found to have subtle, but important, neurologic findings...
January 5, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30536046/reviews-based-on-the-17th-endorama-meeting
#15
EDITORIAL
Kostas B Markou, Neoklis Georgopoulos
No abstract text is available yet for this article.
December 7, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30515667/correction-to-unusual-presentation-of-recurrent-papillary-thyroid-microcarcinoma-with-neck-muscles-and-skin-dissemination
#16
Alessandro Sindoni, Carlo Gobitti, Sandro Sulfaro, Vittorio Giacomarra, Eugenio Borsatti
The original version of this article unfortunately contained a mistake. The title of this article was rendered incorrectly; the correct title is as follows: Unusual presentation of recurrent papillary thyroid microcarcinoma with neck muscles and skin dissemination.
December 4, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30519831/the-past-decade-in-type-2-diabetes-and-future-challenges
#17
REVIEW
Jihad A Haddad, Aiman N Haddad
There is today an exponential increase in prevalence of type 2 diabetes mellitus (T2DM), especially in young people. This downward shift in age of onset of T2DM has been shown by abundant evidence to be due to an increase in obesity among the young, the latter mainly attributable to unhealthy dietary habits and a sedentary lifestyle. It is therefore obvious that the prevention of diabetes rather its treatment is of is paramount importance. In the past decade, because concerns about the safety of antidiabetic agents took precedence over the issue of efficacy, almost all studies have been diabetes CVOTs and not traditional CVOTs...
December 2018: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30515666/transsphenoidal-surgery-for-pituitary-adenomas-early-results-from-a-single-center
#18
I Karamouzis, M Caputo, C Mele, A Nuzzo, M Zavattaro, P Car, G Panzarasa, F Prodam, P Marzullo, Gianluca Aimaretti
OBJECTIVE: To evaluate early results of transsphenoidal surgery for pituitary adenomas. DESIGN: Retrospective evaluation of 90 consecutive patients undergoing endoscopic pituitary adenoma surgery (2007-2016) at "Maggiore della Carità" Hospital in Novara, Italy. Age at diagnosis, sex, symptoms at presentation, hormonal and radiological data, complications of surgery, and short-term follow-up information were collected. RESULTS: The majority of patients were male (M/F: 1...
December 2018: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30511333/guidelines-for-exercise-during-normal-pregnancy-and-gestational-diabetes-a-review-of-international-recommendations
#19
Dimitra Savvaki, Eleftheria Taousani, Dimitrios G Goulis, Efrosini Tsirou, Evangelia Voziki, Helen Douda, Nikolaos Nikolettos, Savvas P Tokmakidis
OBJECTIVE: Τo summarize and present the main guidelines for exercise during normal pregnancy and pregnancy complicated by gestational diabetes mellitus (GDM). METHODS: Relevant guidelines were retrieved through the electronic databases PubMed (MEDLINE), CENTRAL (Cochrane), and Embase; reference sections of the retrieved publications; proceedings of the main congresses in the field; and websites of relevant organizations published during the years 2000-2018. RESULTS: All guidelines recommend aerobic training from 60 to 150 min/week, with an upper limit of 30 min/day...
December 2018: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30460459/precocious-or-early-puberty-in-patients-with-combined-pituitary-hormone-deficiency-due-to-pou1f1-gene-mutation-case-report-and-review-of-possible-mechanisms
#20
REVIEW
Firdevs Baş, Zehra Yavaş Abalı, Güven Toksoy, Şükran Poyrazoğlu, Rüveyde Bundak, Çağrı Güleç, Zehra Oya Uyguner, Feyza Darendeliler
Central precocious puberty (CPP) or early puberty (EP) is a rare entity in combined pituitary hormone deficiency (CPHD), the latter caused by mutations in pituitary transcription factor genes. The early onset of puberty in two patients with CPHD with POU1F1 gene mutation was evaluated. A 3-month-old boy was diagnosed with central hypothyroidism, and L-thyroxine was commenced. He was referred for the evaluation of short stature at 20 months of age. Anthropometric evaluation revealed severe short stature (- 6...
December 2018: Hormones: International Journal of Endocrinology and Metabolism
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