journal

Hormones: International Journal of Endocrinology and Metabolism

journal
https://read.qxmd.com/read/31960359/bicentennial-of-the-discovery-of-selenium-commemorated-at-the-museum-of-natural-history-in-athens
#1
EDITORIAL
Leonidas H Duntas, Jacques Dumont
No abstract text is available yet for this article.
January 20, 2020: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31960358/selenium-involvement-in-mitochondrial-function-in-thyroid-disorders
#2
REVIEW
Monica Livia Gheorghiu, Corin Badiu
Selenium (Se), an important oligoelement, is a component of the antioxidant system. Over the last decade, it has been ever more frequently discussed in the context of thyroid disorders. Graves' disease and Hashimoto's thyroiditis, differentiated thyroid cancer, and even endemic goiter may have common triggers that are activated by excess reactive oxygen species (ROS), which are involved in various stages of the pathogenesis of thyroid disorders. Most oxidative events occur in mitochondria, organelles that contain enzymes with Se as a cofactor...
January 20, 2020: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31950464/multiple-hormone-secretion-may-indicate-worse-prognosis-in-patients-with-ectopic-cushing-s-syndrome
#3
Ieva Lase, Ieva Strele, Malin Grönberg, Gordana Kozlovacki, Staffan Welin, Eva Tiensuu Janson
PURPOSE: Ectopic Cushing's syndrome (ECS) caused by an ACTH secreting neuroendocrine neoplasm (NEN) is a rare and challenging condition. We aimed to detect predictive and prognostic parameters for ECS patients identified from a retrospective, comprehensive cohort of NENs treated at a tertiary referral center. METHODS: Medical records of 886 patients with NENs were reviewed. We identified 51 patients with ECS (33 females/18 men); mean age 52 ± 15 years (SD)...
January 16, 2020: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31933100/pituitary-tumors-epidemiology-and-clinical-presentation-spectrum
#4
REVIEW
Marta Araujo-Castro, Víctor Rodríguez Berrocal, Eider Pascual-Corrales
Pituitary tumors (PTs) are a heterogeneous group of lesions of the central nervous system that are usually benign. Most of them occur sporadically, but 5% can do so within family syndromes, usually at a young age. There are differences by sex, age, race, and genetic factors in the prevalence of different tumor cell types and clinical presentation. Functioning-PTs (FPTs) are usually diagnosed earlier than non-functioning PTs (NFPTs). However, this depends on the PT type. Headaches and visual disturbances are the most frequent mass-effect symptoms, but seizures or hydrocephalus may also occur...
January 14, 2020: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31925736/the-effects-of-postnatal-exposure-of-endocrine-disruptors-on-testicular-function-a-systematic-review-and-a-meta-analysis
#5
REVIEW
Despoina Bliatka, Meletios P Nigdelis, Katerina Chatzimeletiou, George Mastorakos, Stefania Lymperi, Dimitrios G Goulis
BACKGROUND: Despite many epidemiological studies having been conducted, the impact of postnatal exposure of endocrine disruptors (EDs) on testicular function remains a controversial issue. AIM: To systematically review the literature and perform a quantitative synthesis to evaluate the effect of EDs on testicular function. MATERIALS AND METHODS: A comprehensive search was conducted in the MEDLINE, Scopus, and CENTRAL databases. Eligible for the systematic review were observational (cross-sectional and cohort) studies with (i) adult men who had a high probability of postnatal exposure to EDs ("exposed"), (ii) adult men who had a low probability of postnatal exposure to EDs ("non-exposed"), and (iii) an outcome of interest [seminal parameters and reproductive hormone concentrations]...
January 10, 2020: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31919677/the-measurement-of-vitamin-d-metabolites-part-i-metabolism-of-vitamin-d-and-the-measurement-of-25-hydroxyvitamin-d
#6
REVIEW
Konstantinos Makris, Christopher Sempos, Etienne Cavalier
It has been more than 80 years since the discovery of vitamin D and its ability to cure rickets in children. Vitamin D is a secosteroid and comes in two distinct forms, vitamin D2 and vitamin D3. During the last 40 years, the synthesis and metabolism of vitamin D were elucidated and more than 50 metabolites of vitamin D have been discovered, though commercial measurement procedures have been developed for only a few of them. The clinical significance of vitamin D in calcium and phosphorus homeostasis is well appreciated...
January 9, 2020: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31919676/correction-to-a-year-in-type-2-diabetes-mellitus-2018-review-based-on-the-endorama-lecture
#7
Stavroula A Paschou, Theodoros Alexandrides
The original version of this article, published on 26 November 2019, contained a mistake. An author's name was misspelled.
January 9, 2020: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31912384/correction-to-reduced-foxo3a-foxl2-and-p27-mrna-expression-in-human-ovarian-tissue-in-premature-ovarian-insufficiency
#8
Nikolaos Thanatsis, Apostolos Kaponis, Vasiliki Koika, Neoklis A Georgopoulos, George O Decavalas
The original version of this article, published 21 October 2019, unfortunately contained a mistake. The presentation of Fig. 1 was incorrect. The corrected figure is given below.
January 7, 2020: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31863347/salt-intake-in-mineralocorticoid-receptor-antagonist-treated-primary-aldosteronism-foe-or-ally
#9
Stelios Fountoulakis, Labrini Papanastasiou, Nikos Voulgaris, Theodora Kounadi, Athina Markou, George P Chrousos, George Piaditis
Mild hyperkalemia is a common side effect of mineralocorticoid receptor antagonist (MRA) treatment of patients with primary aldosteronism (PA), which can be worsened by instructions to minimize salt intake. Our objective was to evaluate the effect of salt consumption on serum potassium levels and mean, mean minimal, and mean maximal systolic and diastolic blood pressure (BP) in MRA-treated hyperkalemic PA patients under relative salt restriction. Seventeen consecutive mildly hyperkalemic MRA-treated PA patients aged 66...
December 21, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31863346/association-between-vitamin-d-and-endometriosis-a-systematic-review
#10
REVIEW
Dimitrios Rafail Kalaitzopoulos, Ioannis G Lempesis, Florentia Athanasaki, Dimitrios Schizas, Eleftherios Pierre Samartzis, Efstratios M Kolibianakis, Dimitrios G Goulis
BACKGROUND: Endometriosis is one of the most common gynecological diseases of reproductive age, with a prevalence of 5-10% and grave consequences for quality of life and fertility. Vitamin D (vit D), a classic regulator of plasma calcium concentration and skeleton mineralization, is also an effective modulator of the immune system. Several studies suggest that immunologic properties attributed to vit D along with vit D receptor (VDR) expression in reproductive tissues may be involved in the pathogenesis of endometriosis...
December 21, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31853818/bone-health-care-in-women-with-breast-cancer
#11
REVIEW
Stavroula Α Paschou, Areti Augoulea, Irene Lambrinoudaki
The aim of this article is to analyze and critically appraise the literature regarding optimal bone health care in women with breast cancer and, more specifically, to present (1) the causes of bone loss in breast cancer patients, (2) the appropriate screening for osteoporosis and fracture risk estimation, (3) optimal prevention and therapeutic strategies for osteoporosis and fractures, (4) the role of antiresorptive agents as adjuvant therapy for the prevention of bone metastases and increase of overall survival, and (5) current data on the possible use of menopausal hormone therapy (MHT) in these patients...
December 18, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31853817/does-exercise-induced-apelin-affect-sarcopenia-a-systematic-review-and-meta-analysis
#12
Jun Hyun Bae, Seong Eun Kwak, Ji Hyun Lee, Zhang Yangjie, Wook Song
PURPOSE/OBJECTIVE: There have been a number of studies on the role of the novel protein apelin, identified in 1998, in improving muscular function and structure in various human organs, as well as on how it is involved in pathological processes. The aim of this systematic review and meta-analysis was to determine the effect of exercise on serum apelin levels to provide up-to-date data for the development of an exercise intervention for older adults. METHODS: We searched for articles in PubMed, Ovid MEDLINE, and EMBASE from database inception to May 31, 2019...
December 18, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31828604/premature-ovarian-insufficiency-in-adolescence-a-chance-for-early-diagnosis
#13
REVIEW
Lina Michala, Katerina Stefanaki, Dimitris Loutradis
Premature ovarian insufficiency (POI) is typically diagnosed when amenorrhea is combined with high gonadotrophins and hypoestrogenemia in a woman under 40 years of age, although, more rarely, POI can develop in adolescence and present with delayed puberty or amenorrhea, depending on the timing of follicular depletion or insult to the ovary. In a proportion of girls, the diagnosis may be made at an early stage of POI, presenting with abnormal uterine bleeding, when some follicular function is still retained...
December 11, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31823341/the-other-view-the-trace-element-selenium-as-a-micronutrient-in-thyroid-disease-diabetes-and-beyond
#14
REVIEW
Lutz Schomburg
Antibiotics are provided for infections caused by bacteria, and statins help to control hypercholesterolemia. When hungry, you need to eat, and when you are deficient in a particular nutrient, the diet should be chosen wisely to provide what is missing. In the matter of providing the essential trace element selenium (Se), there are two different but partly overlapping views on its nature and requirements. Some consider it a medication that should be given to a subset of more or less well-defined (thyroid) patients only, in order to alleviate symptoms, to improve the course of the disease or even to provide a cure, alone or in an adjuvant mode...
December 11, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31823340/diagnosis-treatment-and-survival-analysis-of-adrenocortical-carcinomas-a-multicentric-study
#15
Pedro Souteiro, Sara Donato, Cláudia Costa, Catarina A Pereira, Joana Simões-Pereira, Joana Oliveira, Sandra Belo, Ana Paula Santos, Helena Cardoso, Valeriano Leite, Davide Carvalho, Isabel Torres
INTRODUCTION: Current guidelines specify controversial areas in adrenocortical carcinomas (ACC), such as optimal follow-up time after remission and identification of prognostic markers. We aim to address these topics by analyzing four reference centers in our country. METHODS: Cross-sectional multicentric study of 69 patients (mean age: 51.7 ± 16.7 years-old; women, 72.5%). Kaplan-Meier survival curves and Cox regression analysis were used to calculate overall survival and its predictors...
December 10, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31820398/effect-of-selenium-supplementation-on-antioxidant-markers-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#16
Motahareh Hasani, Shirin Djalalinia, Maryam Khazdooz, Hamid Asayesh, Maryam Zarei, Armita Mahdavi Gorabi, Hossein Ansari, Mostafa Qorbani, Ramin Heshmat
AIM: The aim of this study is the systematic review and meta-analysis of controlled trial studies to assess the antioxidant effects of selenium (Se) supplementation. METHODS: The systematic review and meta-analysis were performed according to the previously published protocol. The PubMed, Web of Sciences, and Scopus databases were meticulously searched for relevant data, without time or language restriction, up to June 1, 2017. All clinical trials which assessed the effect of Se supplementation on antioxidant markers, including oxidative stress index (OSI), antioxidant potency composite (APC) index, plasma malonaldehyde (MDA), total antioxidant capacity (TAC), antioxidant enzymes (superoxide dismutase (SOD), glutathione peroxidase (GPX), catalase (CAT)), and total antioxidant plasma (TAP), were included...
December 10, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31776808/iodine-nutrition-in-pregnant-and-breastfeeding-women-sufficiency-deficiency-and-supplementation
#17
REVIEW
Hossein Delshad, Fereidoun Azizi
Iodine is a micronutrient used by the thyroid gland to produce thyroid hormones, which manage different aspects of body metabolism. Humans depend on exogenous sources of iodine to maintain the normal concentration of thyroid hormones. Pregnancy alters iodine turnover and is associated with significant changes in thyroid function. Daily iodine requirement during pregnancy increases to 250 μg, compared with 150 μg for nonpregnant women. According to recent guidelines of scientific organizations, to improve maternal thyroid status and to prevent child neurocognitive defects, all pregnant and breastfeeding women should take 150 μg of iodine supplementation, not only in iodine-deficient regions but also in iodine-sufficient areas...
November 27, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31630372/a-year-in-type-2-diabetes-mellitus-2018-review-based-on-the-endorama-lecture
#18
REVIEW
Paschou Sa, Theodoros Alexandrides
The aim of this article is to review and present the most important studies published in the field of type 2 diabetes mellitus (T2DM) during 2018. These studies were presented in a lecture given on this topic at the Endorama Meeting in Patras, Greece, in January 2019. In order to identify the most important and relevant articles, a search in the English language was conducted in PubMed for publications up to the end of December 2018, with special attention paid to publications in high impact factor journals...
November 26, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31768940/the-association-between-vitamin-d-status-and-infectious-diseases-of-the-respiratory-system-in-infancy-and-childhood
#19
REVIEW
Dimitra Zisi, Anna Challa, Alexandros Makis
PURPOSE: Respiratory tract infections (RTIs) are a major cause of illness worldwide and the most common cause of hospitalization for pneumonia and bronchiolitis. These two diseases are the leading causes of morbidity and mortality among children under 5 years of age. Vitamin D is believed to have immunomodulatory effects on the innate and adaptive immune systems by modulating the expression of antimicrobial peptides, like cathelicidin, in response to both viral and bacterial stimuli. The aim of this review is to summarize the more recently published data with regard to potential associations of 25-hydroxyvitamin D [25(OH)D] with infectious respiratory tract diseases of childhood and the possible health benefits from vitamin D supplementation...
November 25, 2019: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/31760587/a-novel-k224t-missense-mutation-in-a-patient-with-men1-syndrome
#20
LETTER
Joanna Tolin, Lisa Reid, Robert A Somer, Farah Hena Morgan
No abstract text is available yet for this article.
November 23, 2019: Hormones: International Journal of Endocrinology and Metabolism
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