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Journals Hormones : International Journ...

Hormones : International Journal of Endocrinology and Metabolism

https://read.qxmd.com/read/38758491/a-schedule-for-tapering-glucocorticoid-treatment-in-patients-with-severe-sars-cov-2-infection-can-prevent-acute-adrenal-insufficiency-in-the-geriatric-population
#1
JOURNAL ARTICLE
Irene Tizianel, Elena Ruggiero, Marianna Torchio, Matteo Simonato, Chiara Seresin, Francesco Bigolin, Ilaria Pivetta Botta, Giulia Bano, Mario Rosario Lo Storto, Carla Scaroni, Filippo Ceccato
OBJECTIVE AND DESIGN: Glucocorticoids (GCs) have been widely used in symptomatic patients for the treatment of COVID-19. The risk for adrenal insufficiency must be considered after GC withdrawal given that it is a life-threatening condition if left unrecognized and untreated. Our study aimed to diagnose adrenal insufficiency early on through a GC reduction schedule in patients with COVID-19 infection. PATIENTS AND MEASUREMENTS: From November 2021 to May 2022, 233 patients were admitted to the Geriatric Division of the University Hospital of Padova with COVID-19 infection...
May 17, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38750304/the-role-of-low-glycemic-index-and-load-diets-in-medical-nutrition-therapy-for-type-2-diabetes-an-update
#2
REVIEW
Eleni Gerontiti, Almog Shalit, Katerina Stefanaki, Paraskevi Kazakou, Dimitrios S Karagiannakis, Melpomeni Peppa, Theodora Psaltopoulou, Stavroula A Paschou
The increasing prevalence of type 2 diabetes mellitus (T2DM) and its microvascular and macrovascular complications necessitate an optimal approach to prevention and management. Medical nutrition therapy serves as the cornerstone of diabetes care, reducing reliance on diabetic medications for glycemic control and mitigating cardiovascular risk. The broadening field of research in the effect of low glycemic index (GI) and/or glycemic load (GL) diets on individuals with T2DM has yielded promising results in the existing literature...
May 16, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38748060/the-interlink-between-thyroid-autoimmunity-and-type-1-diabetes-and-the-impact-on-male-and-female-fertility
#3
REVIEW
Sanja Medenica, Vukasin Stojanovic, Umberto Capece, Rossella Mazzilli, Milica Markovic, Virginia Zamponi, Tanja Vojinovic, Silvia Migliaccio, Giuseppe Defeudis, Francesca Cinti
The aim of this review is to discuss the several interconnections between thyroid autoimmunity and type 1 diabetes in terms of epidemiology, immunoserology, genetic predisposition, and pathogenic mechanisms. We will also analyze the impact of these conditions on both male and female fertility. A literature search was carried out using the MEDLINE/PubMed, Scopus, Google Scholar, ResearchGate, and Clinical Trials Registry databases with a combination of keywords. It was found that the prevalence of thyroid autoantibodies in individuals with type 1 diabetes (T1DM) varied in different countries and ethnic groups from 7 to 35% in both sexes...
May 15, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38740711/corticotropin-releasing-hormone-deficiency-results-in-impaired-analgesic-response-during-cfa-induced-inflammation
#4
JOURNAL ARTICLE
Efthymia Karagianni, Olga Rassouli, Smaragda Poulaki, Eirini Dermitzaki, George Liapakis, Andrew N Margioris, Maria Venihaki
PURPOSE: Corticotropin-releasing hormone (CRH) plays an important role in relief of pain by releasing analgesia-associated molecules in several inflammatory states. During inflammation, peripheral CRH acts on cells of the immune system to stimulate the local expression of proopiomelanocortin (POMC) and the production of β-endorphin, which in turn binds to opioid receptors on sensory neurons to produce antinociception. In the present study, we further investigated the role of endogenous CRH in inflammatory pain by determining the effects of Crh-deficiency on this process...
May 14, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38647964/indications-of-younger-age-at-menarche-in-greek-adolescents-but-with-no-relation-to-body-mass-index
#5
JOURNAL ARTICLE
Anastasia Papageorgiou, Evangelia Charmandari, Vasiliki Efthymiou, Dimitrios Vlachakis, Flora Bacopoulou
PURPOSE: This study aimed to present recent trends in the pubertal timing of a Greek female sample. METHODS: Data were collected retrospectively from medical records of healthy females aged 6-18 years who attended a tertiary Adolescent Friendly Health Center over a 5-year period (2016-2020) and included gestational age, birth anthropometrics, and age of thelarche and/or pubarche and/or menarche, along with corresponding anthropometric, hormonal, and biochemical measurements...
April 22, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38639888/the-effect-of-gnrh-a-on-the-angiogenesis-of-endometriosis
#6
JOURNAL ARTICLE
Theodoros Filindris, Efthymia Papakonstantinou, Maria Keramida, Eleftherios Panteris, Sotiris Kalogeropoulos, Neoklis Georgopoulos, Fuminori Taniguchi, George Adonakis, Tasuku Harada, Apostolos Kaponis
PURPOSE: Neoangiogenesis is necessary for adhesion and invasiveness of endometriotic lesions in women affected by endometriosis. Vascular endothelial growth factor (VEGF) is one of the main components of angiogenesis and is part of the major pathway tissue factor (TF)-protease activated receptor-2 (PAR-2)-VEGF that leads to neoangiogenesis. Specificity protein 1 (SP1) is a transcriptional factor that has recently been studied for its crucial role in angiogenesis via a specific pathway...
April 19, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38632216/evaluation-of-the-relation-between-subclinical-systolic-dysfunction-defined-by-four-dimensional-speckle-tracking-echocardiography-and-growth-differentiation-factor-15-levels-in-patients-with-acromegaly
#7
JOURNAL ARTICLE
Busra Firlatan, Ugur Nadir Karakulak, Vedat Hekimsoy, Burcin Gonul Iremli, Incilay Lay, Deniz Yuce, Selcuk Dagdelen, Giray Kabakci, Tomris Erbas
PURPOSE: In patients with acromegaly, the long-term presence of elevated GH and IGF-1 levels is associated with an unfavorable cardiovascular risk profile. We aimed to assess the relationship of four-dimensional speckle tracking echocardiographic (4DSTE) measurements with growth differentiation factor-15 (GDF-15) levels and the Framingham Cardiovascular Risk Score (FRS) in patients with acromegaly. METHODS: A single-center, cross-sectional study was conducted. The study included 40 acromegaly and 32 age- and gender-matched controls...
April 18, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38632215/once-upon-a-time-in-anatolia-the-kings-with-bulging-eyes
#8
REVIEW
Hulya Elbe
The Hittite Empire, formed by the Hittites who settled in central Anatolia at the beginning of the second millennium BC, has left behind rich archeological remains. In this historical review, statues of the Hittite priest-kings, King Idrimi, King Šuppiluliuma, and King Tarhunza, who ruled in these lands in ancient times, are analyzed. Graves' disease (GD) is the most common cause of hyperthyroidism. Patients with GD are also at risk of developing Graves' orbitopathy (GO). Upper eyelid retraction and exophthalmos (bulging eyes) are common in patients diagnosed with GO...
April 18, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38632214/-female-and-male-hormones-in-greek-secondary-education-biology-textbooks
#9
LETTER
Anastasia Armeni, Georgios Ampatzidis
No abstract text is available yet for this article.
April 18, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38632213/illness-stress-induced-transient-hyperglycemia-in-a-patient-with-a-novel-yipf5-homozygous-missense-variant-expanding-the-phenotype
#10
REVIEW
Aristeidis Giannakopoulos, Dionisios Chrysis
A recently described type of neonatal diabetes mellitus is caused by mutations in the YIPF5 gene and is combined with manifestations from the central nervous system, including developmental delay, epilepsy, and microcephaly. The molecular pathophysiology behind this phenotype involves the breakdown of the endoplasmic reticulum stress response due to the loss of protein folding capacity. This results in overt diabetes present from very early in life. Herein, we describe a patient with a newly reported variant in the YIPF5 gene, who presented with short events of severe hyperglycemia, induced by the stress of common illnesses, which completely resolved after recovery...
April 18, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38625627/synergistic-neuroprotective-action-of-prolactin-and-17%C3%AE-estradiol-on-kainic-acid-induced-hippocampal-injury-and-long-term-memory-deficit-in-ovariectomized-rats
#11
JOURNAL ARTICLE
Karen De la Torre, Marco Antonio Cerbón, Gladys Molina-Salinas, José Eduardo Suárez-Santiago, Jean-Pascal Morin, Gabriel Roldán-Roldán, Ofir Picazo
PURPOSE: The neuroprotective actions of the ovarian hormone 17β-estradiol (E2) against different brain lesions have been constantly confirmed in a variety of models including kainic acid (KA) lesions. Similarly, the pituitary hormone prolactin (PRL), traditionally associated with lactogenesis, has recently been linked to a large diversity of functions, including neurogenesis, neuroprotection, and cognitive processes. While the mechanisms of actions of E2 as regards its neuroprotective and behavioral effects have been extensively explored, the molecular mechanisms of PRL related to these roles remain under investigation...
April 16, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38625626/thyroid-dysfunction-due-to-trace-element-deficiency-not-only-selenium-but-also-zinc
#12
REVIEW
Kohei Nagano, Yuma Motomura, Hironori Bando, Masaaki Yamamoto, Keitaro Kanie, Kei Yoshino, Yushi Hirota, Tomoko Yamada, Michiko Takahashi, Hidenori Fukuoka, Wataru Ogawa
INTRODUCTION: Levels of serum selenium (Se) and zinc (Zn) decrease when total parental nutrition (TPN) is administered without trace element supplementation for just a few weeks. These trace elements are involved in thyroid hormone metabolism and their deficiencies cause thyroid dysfunction. However, there have been few reports on the details of its clinical course. CASE PRESENTATION: A 50-year-old man presented with thyroid dysfunction due to Se and Zn deficiency...
April 16, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38619812/endobridge-2023-highlights-and-pearls
#13
REVIEW
Bulent Okan Yildiz, Cesar Luiz Boguszewski, Margaret Cristina da Silva Boguszewski, Luca Busetto, Ozlem Celik, Ghada El-Hajj Fuleihan, Dimitrios G Goulis, Gary D Hammer, Megan R Haymart, Gregory Kaltsas, Jennifer R Law, Amanda Yuan Ling Lim, Anton Luger, Djuro Macut, Barbara McGowan, Michael McClung, Alexander Dimitri Miras, Mary Elizabeth Patti, Robin P Peeters, Duarte Pignatelli, Hamayle Saeed, Jennifer Sipos, Constantine A Stratakis, Marina Tsoli, A J van der Lely, Selma F Witchel, Dilek Yazici
EndoBridge 2023 took place on October 20-22, 2023, in Antalya, Turkey. Accredited by the European Council, the 3-day scientific program of the 11th Annual Meeting of EndoBridge included state-of-the-art lectures and interactive small group discussion sessions incorporating interesting and challenging clinical cases led by globally recognized leaders in the field and was well attended by a highly diverse audience. Following its established format over the years, the program provided a comprehensive update across all aspects of endocrinology and metabolism, including topics in pituitary, thyroid, bone, and adrenal disorders, neuroendocrine tumors, diabetes mellitus, obesity, nutrition, and lipid disorders...
April 15, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38619811/when-rare-diseases-crisscross-within-the-same-patient-von-hippel-lindau-and-type-1-gastric-neuroendocrine-tumor
#14
JOURNAL ARTICLE
Krystallenia I Alexandraki, Ariadni Spyroglou, Paraskevi Xekouki, Konstantinos I Bramis, Georgios Kyriakopoulos, Konstantinos Barkas, Ioannis S Papanikolaou, George Mastorakos, Manousos Konstadoulakis
Von-Hippel-Lindau (VHL) is a genetic multisystem disorder characterized by visceral cysts and benign and malignant tumors in various organs. Herein, we present the case of a 23-year-old woman with VHL presenting with multiple gastric neuroendocrine neoplasms (gNENs) type 1 in the context of chronic autoimmune gastritis (CAG). Although gNENs are not acknowledged as a typical entity in VHL patients, in the present case, gNENs were composed of neoplastic cells with clear cytoplasm usually seen in tumors related to VHL disease...
April 15, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38607611/evaluation-of-the-possible-impact-of-the-fear-of-hypoglycemia-on-diabetes-management-in-children-and-adolescents-with-type-1-diabetes-mellitus-and-their-parents-a-cross-sectional-study
#15
JOURNAL ARTICLE
Ourania Andreopoulou, Eirini Kostopoulou, Eleni Kotanidou, Sophia Daskalaki, Angeliki Vakka, Assimina Galli-Tsinopoulou, Bessie E Spiliotis
PURPOSE: Hypoglycemia represents a significant source of anxiety for children with type 1 diabetes mellitus (T1DM) and their caretakers. Fear of hypoglycemia (FoH) was measured in children and adolescents with T1DM as well as in their parents using an established research instrument, the Hypoglycemia Fear Survey (HFS). METHODS: This is a two-center, cross-sectional study involving 100 children and adolescents aged 6-18 years old diagnosed with T1DM. One parent of each child also participated in the study...
April 12, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38581565/association-between-serum-tsh-concentration-and-bone-mineral-density-an-umbrella-review
#16
JOURNAL ARTICLE
Martyna Dziedzic, Michał Bonczar, Patryk Ostrowski, Bartłomiej Stachera, Dawid Plutecki, Monika Buziak-Bereza, Alicja Hubalewska-Dydejczyk, Jerzy Walocha, Mateusz Koziej
INTRODUCTION: The aim of this study was to summarize the results of previous studies, standardize the data, and present new statistical results in order to provide physicians with clinically significant outcomes regarding the association between serum TSH concentration and bone mineral density (BMD). METHODS: To perform this umbrella review, a systematic search was conducted in which major online medical databases, such as PubMed, Web of Science, Embase, Scopus, Cochrane Library, and Google Scholar, were searched for meta-analyses and systematic reviews regarding the effect of TSH on BMD...
April 6, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38564143/the-causal-impact-of-gut-microbiota-on-circulating-adipokine-concentrations-a-two-sample-mendelian-randomization-study
#17
JOURNAL ARTICLE
Tongxin Zhang, Jingyu Liu, Xiao Liu, Qian Wang, Huawei Zhang
PURPOSE: Evidence from previous experimental and observational research demonstrates that the gut microbiota is related to circulating adipokine concentrations. Nevertheless, the debate as to whether gut microbiome composition causally influences circulating adipokine concentrations remains unresolved. This study aimed to take an essential step in elucidating this issue. METHODS: We used two-sample Mendelian randomization (MR) to causally analyze genetic variation statistics for gut microbiota and four adipokines (including adiponectin, leptin, soluble leptin receptor [sOB-R], and plasminogen activator inhibitor-1 [PAI-1]) from large-scale genome-wide association studies (GWAS) datasets...
April 2, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38564142/reference-intervals-for-thyroid-function-from-the-fifth-to-seventh-day-of-life-in-twin-pregnancy-preterm-neonates-an-8-year-retrospective-study
#18
JOURNAL ARTICLE
Xin-Ting Zheng, Xin Lin, Mei Ma, Shu-Hua Lai, Chang-Yi Yang
PURPOSE: The immature and developing hypothalamic-pituitary-thyroid axis leads to different levels of thyroid function in twin neonates, including free thyroxine (FT4), free triiodothyronine (FT3), and thyroid stimulating hormone (TSH) levels. No reference intervals for twins have been established until now. To compensate for this lack, we collected data and established this standard across different gestational ages (GAs) and sexes. METHODS: A total of 273 pairs of neonates admitted to the NICU in Southeast China from 2015 to 2022 were included...
April 2, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38536642/clinical-prediction-model-for-primary-aldosteronism-subtyping-and-special-focus-on-adrenal-volumetric-assessment
#19
JOURNAL ARTICLE
Tugba Barlas, Erhan Turgut Ilgit, Mehmet Koray Akkan, Emetullah Cindil, Isil Imge Gultekin, Hulya Nur Sodan, Mehmet Muhittin Yalcin, Ethem Turgay Cerit, Sinan Sozen, Mujde Akturk, Fusun Toruner, Ayhan Karakoc, Alev Eroglu Altinova
PURPOSE: Our aim was to develop a prediction model based on a simple score with clinical, laboratory, and imaging findings for the subtype diagnosis of primary aldosteronism (PA). The contribution of adrenal volumetric assessment to PA subtyping was also investigated. METHODS: Thirty-five patients with adequate cannulation in adrenal venous sampling (AVS) were included. Laboratory data, the saline infusion test (SIT), and the AVS results of patients with PA were retrospectively evaluated...
March 27, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38526829/expanding-the-phenotypic-spectrum-of-lhcgr-signal-peptide-insertion-variant-novel-clinical-and-allelic-findings-causing-leydig-cell-hypoplasia-type-ii
#20
JOURNAL ARTICLE
Heba Amin Hassan, Inas Mazen, Aya Elaidy, Alaa K Kamel, Noura R Eissa, Mona L Essawi
PURPOSE: Leydig cell hypoplasia (LCH) type II is a rare disease with only a few cases reported. Patients presented with hypospadias, micropenis, undescended testes, or infertility. In this study, we report a new patient with compound heterozygous variants in the LHCGR gene and LCH type II phenotype. METHODS: Whole exome sequencing (WES) was performed followed by Sanger sequencing to confirm the detected variants in the patient and his parents. RESULTS: A novel missense variant (p...
March 25, 2024: Hormones: International Journal of Endocrinology and Metabolism
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