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Journals Hormones : International Journ...

Hormones : International Journal of Endocrinology and Metabolism

https://read.qxmd.com/read/38536642/clinical-prediction-model-for-primary-aldosteronism-subtyping-and-special-focus-on-adrenal-volumetric-assessment
#1
JOURNAL ARTICLE
Tugba Barlas, Erhan Turgut Ilgit, Mehmet Koray Akkan, Emetullah Cindil, Isil Imge Gultekin, Hulya Nur Sodan, Mehmet Muhittin Yalcin, Ethem Turgay Cerit, Sinan Sozen, Mujde Akturk, Fusun Toruner, Ayhan Karakoc, Alev Eroglu Altinova
PURPOSE: Our aim was to develop a prediction model based on a simple score with clinical, laboratory, and imaging findings for the subtype diagnosis of primary aldosteronism (PA). The contribution of adrenal volumetric assessment to PA subtyping was also investigated. METHODS: Thirty-five patients with adequate cannulation in adrenal venous sampling (AVS) were included. Laboratory data, the saline infusion test (SIT), and the AVS results of patients with PA were retrospectively evaluated...
March 27, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38526829/expanding-the-phenotypic-spectrum-of-lhcgr-signal-peptide-insertion-variant-novel-clinical-and-allelic-findings-causing-leydig-cell-hypoplasia-type-ii
#2
JOURNAL ARTICLE
Heba Amin Hassan, Inas Mazen, Aya Elaidy, Alaa K Kamel, Noura R Eissa, Mona L Essawi
PURPOSE: Leydig cell hypoplasia (LCH) type II is a rare disease with only a few cases reported. Patients presented with hypospadias, micropenis, undescended testes, or infertility. In this study, we report a new patient with compound heterozygous variants in the LHCGR gene and LCH type II phenotype. METHODS: Whole exome sequencing (WES) was performed followed by Sanger sequencing to confirm the detected variants in the patient and his parents. RESULTS: A novel missense variant (p...
March 25, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38498234/correction-comparison-of-clinical-characteristics-of-a-pediatric-cohort-with-combined-pituitary-hormone-deficiency-caused-by-mutation-of-the-prop1-gene-or-of-other-origins
#3
Agata Zygmunt-Górska, Małgorzata Wójcik, Aleksandra Gilis-Januszewska, Anna Starmach, Mirosław Bik-Multanowski, Jerzy B Starzyk
No abstract text is available yet for this article.
March 18, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38498233/correction-the-neurohypophyseal-hormone-oxytocin-and-eating-behaviors-a-narrative-review
#4
Michele Iovino, Tullio Messana, Simonetta Marucci, Domenico Triggiani, Vito Angelo Giagulli, Edoardo Guastamacchia, Giuseppina Piazzolla, Giovanni De Pergola, Giuseppe Lisco, Vincenzo Triggiani
No abstract text is available yet for this article.
March 18, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38485876/determinants-of-health-related-quality-of-life-of-patients-with-type-2-diabetes-and-multimorbidity-a-cross-sectional-study
#5
JOURNAL ARTICLE
Kyriakos Kintzoglanakis, Leonidas Pavlou-Skantzis, Tatiana Themeli, Miltiades Kyprianou, Stavroula A Paschou
PURPOSE: To examine the determinants of health-related quality of life (HRQoL) of patients with type 2 diabetes (PwD) and multimorbidity (MM) (at least one co-occurring condition besides T2D) among sociodemographic, disease-related, and MM variables and the association of MM with therapeutic targets. METHODS: A total of 179 PwD attending primary care (PC) in Greece answered the 15 dimension HRQoL (15D) questionnaire between August 2019 and October 2020. Sociodemographic, disease-related, and MM characteristics were recorded...
March 15, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38472648/anabolic-myokine-responses-and-muscular-performance-following-8-weeks-of-autoregulated-compared-to-linear-resistance-exercise-in-recreationally-active-males
#6
JOURNAL ARTICLE
Hamid Ghobadi, Seyyed Reza Attarzadeh Hosseini, Amir Rashidlamir, Gholam Rasul Mohammad Rahimi
BACKGROUND: To date, no studies, to our knowledge, have compared the efficacy of autoregulated periodized and linear resistance exercises on anabolic myokines and muscular performance among recreationally active individuals. This study aimed to compare the effects of an 8-week autoregulated periodized resistance exercise (APRE) program with a linear resistance exercise (LRE) program on insulin-like growth factor-1 (IGF-1), follistatin (FST), myostatin (MST), body composition, muscular strength, and power in recreationally active males...
March 13, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38472647/animal-studies-on-glucagon-like-peptide-1-receptor-agonists-and-related-polyagonists-in-nonalcoholic-fatty-liver-disease
#7
REVIEW
Chara Tsiampali, Ilias D Vachliotis, Antonis Goulas, Stergios A Polyzos
Nonalcoholic fatty liver disease (NAFLD) is a prevalent metabolic liver disease closely associated with the epidemics of obesity and type 2 diabetes mellitus (T2DM), but without licensed pharmacological treatment to date. As glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) are approved anti-diabetic and anti-obesity medications, they were also considered a potential therapeutic option for NAFLD. Preclinical studies suggest that GLP-1RAs have a beneficial effect on major NAFLD histological outcomes, i...
March 12, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38457064/spontaneous-hypoglycemia-should-we-mind-the-gap-long-term-follow-up-of-healthy-people-who-met-whipple-s-triad-criteria
#8
JOURNAL ARTICLE
Jan Adelmeyer, Christian Marcel Schauer, Peter Herbert Kann
CONTEXT: Patients discharged as "healthy" with the symptoms of spontaneous hypoglycemia, commonly known as Whipple's triad, need more attention. OBJECTIVE: Characterization and long-term follow-up of symptom development in patients with spontaneous hypoglycemia discharged as "healthy". The objective was to ascertain whether any conditions related to the symptoms were diagnosed during the follow-up period. METHODS: Retrospective analysis of patient data and evaluation of a specific questionnaire on the development of symptoms of spontaneous hypoglycemia...
March 8, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38443586/thyroid-stimulating-hormone-levels-are-associated-with-estradiol-levels-and-impact-reproductive-outcomes-in-preconceptionally-euthyroid-women-undergoing-their-first-ivf-icsi-cycles
#9
JOURNAL ARTICLE
Yuchao Zhang, Jiaheng Li, Yanli Liu, Zhen Li, Yichun Guan
PURPOSE: Controlled ovarian hyperstimulation (COH) has been reported to affect thyroid function; however, the impact of thyroid-stimulating hormone (TSH) levels during COH on embryo development and early reproductive outcomes has largely not been determined. Therefore, the aim of the present study was to investigate whether TSH levels are associated with COH and impact early reproductive outcomes in preconceptionally euthyroid women. METHODS: This was a prospective cohort study...
March 6, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38421590/mitigating-bisphenol-a-induced-apoptosis-in-kgn-cells-the-therapeutic-role-of-1-25-dihydroxyvitamin-d-3-through-upregulation-of-pgc-1%C3%AE-expression-and-inhibition-of-the-mitochondrial-cytochrome-c-pathway
#10
JOURNAL ARTICLE
Liting Tang, Ke Du, Kaiming Luo, Long Wang, Fei Hua
PURPOSE: This study investigated the potential of 1,25-dihydroxyvitamin D3 (1,25(OH)2 VD3 ) to mitigate bisphenol A (BPA)-induced apoptosis in human ovarian granulosa KGN cells with the aim of establishing a theoretical foundation for understanding of how vitamin D improved ovarian function in patients with polycystic ovary syndrome (PCOS). METHODS: The impact of varying concentrations of BPA and 1,25(OH)2 VD3 on KGN cell viability was elucidated. It was established that BPA-induced apoptosis in KGN cells...
February 29, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38421589/reversibility-of-disturbed-pituitary-function-in-pediatric-conditions-with-psychological-stressors-implications-for-clinical-practice
#11
REVIEW
Aristeidis Giannakopoulos, Dionisios Chrysis
The complex communication network between the central nervous system and the hypothalamic-pituitary axis forms the basis of endocrine functional plasticity, which facilitates adaptation to changing internal and external conditions, but also makes it vulnerable to the negative effects of stressful psychological factors. Herein, clinical conditions such as functional hypothalamic amenorrhea, eating disorders, growth faltering, post-traumatic stress disorder, and pubertal disorders that may emerge during childhood or adolescence, their origin possibly including psychological stressors, are analyzed regarding their genetic susceptibility and reversibility of endocrine function...
February 29, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38421588/challenges-and-pitfalls-in-the-management-of-endocrine-toxicities-from-immune-checkpoint-inhibitors-a-case-presentation-of-synchronous-thyrotoxicosis-and-primary-adrenal-insufficiency-in-a-melanoma-patient
#12
REVIEW
Calogera Claudia Spagnolo, Irene Campo, Alfredo Campennì, Davide Cardile, Salvatore Cannavò, Nicola Silvestris, Mariacarmela Santarpia, Rosaria Maddalena Ruggeri
BACKGROUND: Immune checkpoint inhibitors have revolutionized the therapeutic approach to several solid tumors, becoming the standard of care for cancer treatment in different disease settings. Despite the fact that these agents are better tolerated than conventional chemotherapy, their use is associated with a specific toxicity profile, so-called immune-related adverse events (irAEs), that can involve several organs. Endocrine irAEs are among the most frequent toxicities (around 10 to 16%) and include hypophysitis, thyroid disorders, adrenalitis, and diabetes mellitus...
February 29, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38396110/relationship-between-body-adiposity-parameters-and-insulin-resistance-a-preliminary-study-of-surrogate-markers-in-japan
#13
JOURNAL ARTICLE
Nanae Tanemura, Tetsuya Kubota, Naoto Kubota, Tsuyoshi Chiba
PURPOSE: According to the Japan National Health and Nutrition Survey 2019, the proportion of people with prediabetes is estimated to be 27.3%. Western-style dietary habits can lead to obesity and a functional abnormality of the adipose tissue, which can cause insulin resistance and predispose one to diabetes. We examined the relationship between insulin resistance using body adiposity parameters as surrogate markers. METHODS: This study enrolled 248 healthy participants to determine the association of six body adiposity parameters, namely, body mass index (BMI), waist circumference (WC), visceral adiposity index (VAI), lipid accumulation product index (LAP), waist circumference-triglyceride index (WTI), and triglyceride (TG)/high-density lipoprotein (HDL) ratio with insulin resistance...
February 24, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38358428/goiter-in-the-qing-dynasty
#14
REVIEW
Shijie Yang, Xiequn Xu
Empress Dowager Cixi, the supreme ruler of China's Qing Dynasty, along with Imperial Concubine Jin, may have suffered from goiter. Our suspicions were aroused by two interesting historical photographs. Herein, we provide a medical interpretation of these historical images in an attempt to present the cases of these two historical figures.
February 15, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38342850/effect-of-different-starting-doses-of-fsh-on-laboratory-and-clinical-outcomes-in-patients-with-moderate-amh-level
#15
JOURNAL ARTICLE
Minli Liu, Cong Wang, Ling He, Xuan Pan, Chengrong Wu, Xin Pu, Xian Pan
BACKGROUND: IVF and ICSI-ET are widely used ART for addressing infertility which have been developed and improved over the last four decades. COS is a crucial step in IVF/ICSI-ET, whereby medications stimulate the ovaries to produce multiple eggs. The success of the procedure depends on the number of eggs retrieved, and individualized ovarian stimulation protocols based on factors like age and ovarian reserve can optimize the chances of obtaining mature oocytes. The optimal starting dose of FSH at moderate AMH levels remains a topic of debate...
February 12, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38340288/impaired-sensitivity-to-thyroid-hormones-is-associated-with-albuminuria-in-the-euthyroid-population-results-from-nhanes
#16
JOURNAL ARTICLE
Zhaoxiang Wang, Menghuan Wu, Tao Pan, Xuelin Zhao, Li Zhang, Fengyan Tang, Ying Pan, Bing Lu, Shao Zhong, Song Bai
PURPOSE: The relationship between thyroid hormone sensitivity and albuminuria remains unclear. We aimed to investigate the association between thyroid hormone sensitivity and the risk of albuminuria in a euthyroid population. METHODS: This cross-sectional study included 7634 euthyroid adults collected from the National Health and Nutrition Examination Survey (NHANES) between 2007 and 2012. Central sensitivity to thyroid hormones was evaluated using the thyroid-stimulating hormone index (TSHI), the thyrotrophic thyroxine resistance index (TT4RI), and the thyroid feedback quantile-based index (TFQI)...
February 10, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38332247/the-clinical-significance-of-calcium-magnesium-ratio-in-primary-hyperparathyroidism-unveiling-a-clinical-association
#17
JOURNAL ARTICLE
Ekin Yiğit Köroğlu, Abbas Ali Tam, Sevgül Fakı, Belma Tural Balsak, Fatma Ayça Edis Özdemir, Didem Özdemir, Oya Topaloğlu, Reyhan Ersoy, Bekir Çakır
PURPOSE: In previous studies, magnesium (Mg) was found to be lower in cases with more severe primary hyperparathyroidism (PHPT) and higher calcium (Ca) levels. This study evaluated the relationship between serum Mg and serum Ca and phosphorus (P) levels in PHPT and their utility in determining the presence of osteoporosis and nephrolithiasis. METHODS: Patients who were followed up with PHPT between March 2019 and March 2023 were analyzed retrospectively. Biochemical data, renal ultrasonography results, dual-energy x-ray absorptiometry (DEXA) reports, and technetium 99 m sestamibi parathyroid scintigraphy reports were obtained...
February 9, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38311659/hnf1a-gene-mutations-and-premature-ovarian-failure-pof-evidence-from-a-clinical-paradigm-combining-mody-3-and-pof
#18
REVIEW
P Xekouki, A Konstantinidou, C Tatsi, A Sertedaki, N Settas, D Loutradis, G P Chrousos, C Kanaka-Gantenbein, C Dacou-Voutetakis, A Voutetakis
Premature ovarian failure (POF) defines the occurrence of ovarian failure prior to the age of 40. It occurs in one out of 100 women but is very rare before age 20 (1:10,000). Maturity-onset diabetes of the young (MODY), caused by mutations in the HNF1A gene, is also a rare disorder; all types of MODY account for 1-2% of adult diabetic cases. These two rare nosologic entities coexisted in an adolescent girl evaluated for delayed puberty. Although this combination could represent a chance association, an interrelation might exist...
February 5, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38311658/priorities-for-efficacy-trials-of-gender-affirming-hormone-therapy-with-estrogen-collaborative-design-and-results-of-a-community-survey
#19
JOURNAL ARTICLE
Shira Grock, Jane Weinreb, Kristen C Williams, Amy Weimer, Sarah Fadich, Reema Patel, Atara Geft, Stanley Korenman
PURPOSE: Treatment guidelines for gender-affirming hormone therapy with estrogen (GAHT-E) recommend specific dosing regimens based on limited data. Well-controlled efficacy trials are essential to tailoring treatment to patient goals as the guidelines recommend. The goal of this study was to take a foundational step toward designing community-centered effectiveness trials for gender-diverse individuals seeking GAHT-E. METHODS: Our team developed a cross-sectional survey based on broad clinical experience and consultation with our community advisory board...
February 5, 2024: Hormones: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38280115/effects-of-letrozole-alone-or-in-combination-with-gonadotropins-on-ovulation-induction-and-clinical-pregnancy-in-women-with-polycystic-ovarian-syndrome-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#20
REVIEW
Saeed Baradwan, Faisal Al-Shalhoub, Majed Saeed Alshahrani, Samah Himayda, Rayan AlSghan, Hussein Sabban, Inass Hassan Ahmad, Marwa Fekry Mohamed El Sayed, Entesar Omar Mohamad, Abdulhadi A AlAmodi, Ahmed Mohamed Abdelhakim, Kareem Shaheen
OBJECTIVE: To compare letrozole in combination with gonadotropins versus letrozole monotherapy in ovulation induction and clinical pregnancy among infertile women with polycystic ovarian syndrome (PCOS). METHODS: Several databases were searched for available clinical trials from inception until March 2023. We selected randomized controlled trials (RCTs) that compared sequential letrozole/gonadotropin versus letrozole alone among infertile women who met the Rotterdam criteria for PCOS...
January 27, 2024: Hormones: International Journal of Endocrinology and Metabolism
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