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Journal of Maternal-fetal & Neonatal Medicine

Lina Salman, Amir Aviram, Roie Holzman, Hadar Hay-Azogui, Eran Ashwal, Eran Hadar, Rinat Gabbay-Benziv
OBJECTIVE: To determine predictors for cesarean delivery (CD) in pregnancies complicated by preterm premature rupture of membranes (PPROM) with an intention for vaginal delivery. MATERIALS AND METHODS: A retrospective cohort analysis of all singleton, preterm deliveries (24 + 0 to 36 + 6 weeks) following PPROM (2007-2014). Exclusion criteria included: cases intended for CD prior to delivery; short interval from PPROM to delivery (< 24 hours); cervical dilatation upon admission ≥ 4 cm; and major fetal anatomical/chromosomal abnormalities...
February 19, 2019: Journal of Maternal-fetal & Neonatal Medicine
Antonio Malvasi, Pasquale Raimondo, Renata Beck, Andrea Tinelli, Krzysztof Marek Kuczkowski
OBJECTIVE: This study analyzes the important role of ultrasonography (IUS) related to the maternal outcomes in women with fetal persistent occiput posterior position (POPP) and asynclitism (A) in labor neuraxial analgesia (LNA). STUDY DESIGN: Prospective assessment of 148 primiparous women diagnosed with the prolonged second stage of labor. Transabdominal and transperineal IUS were used to detect fetal head position and to evaluate the angle of progression (AOP) and pubic arch angle (PAA)...
February 19, 2019: Journal of Maternal-fetal & Neonatal Medicine
Nicolas Belhomme, Alain Lescoat, Alice Ballerie, Florence Rouget, Gwenaelle Le Bouar, Philippe Loget, Leïla Caillault, Patrick Jego
No abstract text is available yet for this article.
February 18, 2019: Journal of Maternal-fetal & Neonatal Medicine
Sabrina Nolan, Nicholas Czuzoj-Shulman, Haim Arie Abenhaim
PURPOSE: Acute leukemias (ALs) are rare but aggressive malignancies. The goal of our study was to determine the incidence, obstetrical, and newborn outcomes of ALs in pregnancy. MATERIALS AND METHODS: We performed a retrospective population-based cohort study on all births reported in the Health-Care Cost and Utilization Project-Nationwide Inpatient Sample between 1999 and 2014. We calculated the incidence of ALs in pregnancy and conducted multivariate logistic regression to obtain adjusted odds ratios for various maternal and newborn outcomes among this population compared to a nonaffected one...
February 17, 2019: Journal of Maternal-fetal & Neonatal Medicine
Mehmet Mutlu, Yakup Aslan, Filiz Aktürk Acar, Şebnem Kader, G Ülçin Bayramoğlu, Gurdal Yılmaz
OBJECTIVE: Neonatal sepsis , especially nosocomial sepsis (NS) is one of the main causes of mortality and morbidity  in neonates. Our aim was to investigate microorganisms responsible of NS and antimicrobial susceptibility patterns and to compare them in the different period. METHODS: Blood culture registers from the Microbiology Laboratory were reviewed for the study population. The neonates with proven NS were enrolled in the study. Microorganisms responsible for NS and antimicrobial susceptibility patterns were recorded Results: The incidence of gram-positive, gram-negative and fungal microorganisms were 61...
February 13, 2019: Journal of Maternal-fetal & Neonatal Medicine
Khadijah I Ismail, Ailish Hannigan, Peter Kelehan, Brendan Fitzgerald, Keelin O'Donoghue, Amanda Cotter
INTRODUCTION: Individual placental and umbilical cord morphometry have been previously identified to have an association with fetal growth. This study aims to identify which of the morphometric measurements in combination are associated with pregnancies with small for gestational age (SGA) infants using digital imaging of the delivered placenta. MATERIAL AND METHODS: This study examined 1005 placentas from consecutively delivered singleton pregnancies in a tertiary center...
February 13, 2019: Journal of Maternal-fetal & Neonatal Medicine
Vivian Melo Corrêa, Edward Araujo Júnior, Antonio Braga, Julio Elito Júnior
OBJECTIVE: To predict birth weight using fetal fractional limb volumes by three-dimensional (3D) ultrasonography in twin pregnancies. METHOD: This prospective observational cohort study evaluated 51 twin pregnancies, including 28 dichorionic and 23 monochorionic pregnancies. Ultrasound examinations were performed up to 5 days before delivery. Birth weight prediction models were developed using the fractional arm volume (FAV), fractional thigh volume (FTV), and Hadlock's formula and were compared with the actual birth weight...
February 13, 2019: Journal of Maternal-fetal & Neonatal Medicine
Luis Del Carpio-Orantes, Ada Lili Rosas-Lozano, Sergio García-Méndez
We present a cohort of pregnant patients who attended evaluation between August to November 2016, during the first wave of Zika in Mexico, studying them in terms of the most important symptomatology, report of positivity to Zika by RT-PCR, search for fetopathies compatible with the syndrome congenito por zika, being the first experience in the Mexican southeast.
February 13, 2019: Journal of Maternal-fetal & Neonatal Medicine
Sarit Avraham, Liat Zakar, Sharon Maslovitz, Jenna Zoabi, Anat Lavie, Yariv Yogev, Ariel Many
AIM: To compare pregnancy outcome of immigrant women who became pregnant to a same ethnicity partner versus a partner from a different ethnicity. METHODS: A retrospective cohort study on all singleton pregnancies of immigrant women who delivered between the years 2011-2015 in a single tertiary University affiliated Hospital. Demographic and obstetrical data were collected. Same ethnicity couples and mixed couples were compared using Pearson chi-square test for dichotomous variables, and Student's T-test for normally distributed continuous variables...
February 13, 2019: Journal of Maternal-fetal & Neonatal Medicine
Manyu Li, Qiuning Bu, Wanyun Gong, Haomin Li, Lin Wang, Shuangshuang Li, Siddharth Sridhar, Patrick Cy Woo, Ling Wang
BACKGROUND & AIMS: The aim of this study was to investigate the positive rate of hepatitis E virus (HEV) infection and the possible adverse outcomes in pregnant women of Qinhuangdao, China. METHODS: Serum samples of 946 pregnant women were collected from July 2017 to October 2017 in Qinhuangdao First Hospital. All samples were tested for anti-HEV IgM and IgG antibodies by enzyme-linked immunosorbent assay (ELISA). HEV RNA was tested by reverse transcription-nested polymerase chain reaction (RT-nPCR) and the PCR products were sequenced...
February 13, 2019: Journal of Maternal-fetal & Neonatal Medicine
Nuran Ustun, Nilnur Eyerci, Nilgun Karadag, Ahmet Yesilyurt, Aysegul Zenciroglu, Nurullah Okumus
BACKGROUND: Vitamin D and its receptor (VDR) have important roles in perinatal lung development. The objective of this study was to investigate the possible association between VDR FokI and TaqI polymorphism and development of respiratory distress syndrome (RDS) in preterm infants. METHOD: A total of 173 premature infants < 34 weeks: 82 with RDS and 91 without RDS were enrolled. Genotyping of VDR polymorphisms were assayed by real-time PCR. Serum 25-hydroxyvitamin D (25-OHD) levels were measured by ELISA in blood samples that were obtained at the time of admission to the neonatal intensive care unit...
February 13, 2019: Journal of Maternal-fetal & Neonatal Medicine
Sarah G Običan, Linda Odibo, Methodius G Tuuli, Alejandro Rodriguez, Anthony O Odibo
OBJECTIVE: To test the hypothesis that third-trimester uterine artery Doppler (UAD) predicts adverse pregnancy and neonatal outcomes in a high-risk population. STUDY DESIGN: This is a nested case control study of women with singleton gestations referred for a fetal growth ultrasound between 24 and 36 weeks. Third-trimester UAD was performed if estimated fetal weight (Hadlock's chart) was <20th percentile as these patients were considered high risk for poor pregnancy outcomes...
February 13, 2019: Journal of Maternal-fetal & Neonatal Medicine
Rebekah J Mccurdy, Jason K Baxter
BACKGROUND: Preterm birth is a leading cause of neonatal morbidity and mortality worldwide; evidence-based strategies to decrease preterm birth are desperately needed. OBJECTIVE: The purpose of this study was to estimate which of three strategies for screening for shortened cervix in asymptomatic low risk women is the most cost-effective in terms of prevention of preterm birth and associated morbidity. STUDY DESIGN: A decision analysis model was developed from available published evidence comparing three strategies in screening asymptomatic low-risk women for shortened cervix: (1) cervicometer with subsequent referral for transvaginal ultrasound, (2) transvaginal ultrasound screening, and (3) no screening...
February 13, 2019: Journal of Maternal-fetal & Neonatal Medicine
Clare L Whitehead, Nicole Cohen, Gerard H A Visser, Dan Farine
Many studies have reported on the association of reduced fetal movements and stillbirth, but little is known about excessive fetal movements and adverse pregnancy outcome. First described in 1977, sudden excessive fetal movement was noted to reflect acute fetal distress and subsequent fetal demise. Subsequently, little was reported regarding this phenomenon until 2012. However, emerging data suggests that 10-30% of women that subsequently suffer a stillbirth describe a single episode of excessive fetal movement prior to fetal demise...
February 11, 2019: Journal of Maternal-fetal & Neonatal Medicine
Lía Ornat, Vanesa Alonso-Ventura, Juan Bueno-Notivol, Peter Chedraui, Faustino R Pérez-López
OBJECTIVE: To compare the effect of misoprostol combined with a cervical single or double-balloon catheter versus misoprostol alone for labor induction of singleton pregnancies with an unfavorable cervix. METHODS: Systematic review and meta-analysis of randomized controlled trials (RCTs) regarding the comparison of two schemes for labor induction of singleton cephalic pregnancies with a Bishop score ≤7 and no contraindication for vaginal delivery. Six research databases were searched for articles published in all languages up to 10 May 2018 comparing misoprostol (oral or vaginal) in combination with a cervical placed single or double balloon catheter versus misoprostol treatment alone...
February 10, 2019: Journal of Maternal-fetal & Neonatal Medicine
Sizhe Chen, Weiwei Cheng, Yan Chen, Xiaohua Liu
OBJECTIVE: We aimed to evaluate the relationship between mode of first delivery with subsequent placenta previa, placenta accreta/increta and significant postpartum hemorrhage (PPH). METHOD: This retrospective cohort study included women with two consecutive singleton deliveries between 2007-2017 at our institution if the women were nulliparous and delivered at term at the time of first delivery. The first pregnancy delivery mode was classified as (1) vaginal delivery, (2) antepartum caesarean delivery (CD) without labor, or (3) intrapartum CD after onset of labor...
February 10, 2019: Journal of Maternal-fetal & Neonatal Medicine
Shelly Soni, Karalyn Pappas, Martin L Lesser, Matthew J Blitz, Stephanie A Augustine, Burton Rochelson
OBJECTIVE: To determine if vaginal misoprostol is more effective than oral misoprostol for cervical ripening in obese women. STUDY DESIGN: A retrospective cohort study of obese women undergoing induction of labor from Jan 2013 to Dec 2016 with singleton, viable pregnancies beyond 37 completed weeks of gestational age. Women with an initial Bishop score of 7 or less, with a cervical dilatation of less than 2 cm, who received either vaginal or oral misoprostol as a cervical ripening agent, were included...
February 10, 2019: Journal of Maternal-fetal & Neonatal Medicine
Hua Wang, Donglan Yuan, Saili Wang, Li Luo, Yu Zhang, Jun Ye, Kuichun Zhu
OBJECTIVE: Recurrent miscarriage (RM) affects about 5% of pregnancies. Etiology of 30-50% RM cases remains unknown. Advanced highly sensitive detection and analysis methods may help solve some of the cases. METHODS: Products of conception from 1155 RM cases were analyzed using classic karyotyping. Some cases without abnormal findings were subjected to next generation DNA sequencing (NGS) and chromosome copy number variation (CNV) analysis. RESULTS: Classic karyotyping identified abnormalities in 56...
February 10, 2019: Journal of Maternal-fetal & Neonatal Medicine
Juan Carlos Bustos, Alvaro Herrera, Waldo Sepulveda
OBJECTIVE: To analyze placental vascular resistance and the role of placental insufficiency in the etiology of reduced fetal growth in fetuses with trisomy 21 as determined by umbilical artery (UA) Doppler velocimetry. METHODS: Second- and third-trimester UA Doppler ultrasound studies were performed in fetuses with trisomy 21 at the time of clinically indicated obstetric ultrasound assessment. The UA pulsatility index (PI) and half-peak systolic velocity deceleration time (hPSV-DT) were measured and recorded...
February 10, 2019: Journal of Maternal-fetal & Neonatal Medicine
Shigeki Matsubara
No abstract text is available yet for this article.
February 7, 2019: Journal of Maternal-fetal & Neonatal Medicine
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