Journals Aging Clinical and Experimenta...

Aging Clinical and Experimental Research
Francesco Saverio Ragusa, Luisa Solimando, Caterina Mandalà, Roberta Masnata, Gregorio Ciulla, Stefano Ciriminna, Francesco La Blasca, Pasquale Mansueto, Nicola Veronese, Mario Barbagallo
BACKGROUND: Only limited studies analyzed a possible relationship between frailty and infections. Our aim was to investigate the possible association between higher multidimensional prognostic index (MPI) values, a tool for evaluating multidimensional frailty, and the prevalence of infectious diseases, including antibiotics' cost and the prevalence of MDR (multidrug resistance) pathogens. METHODS: Older patients, affected by COVID-19, were enrolled in the hospital of Palermo over four months...
March 25, 2023: Aging Clinical and Experimental Research
QiangJi Bao, XiaoDong Huang, XinTing Wu, ShuJun Chen, JinCai Yang, JingNi Zhang, Jing Li, MingFei Yang
BACKGROUND: Frailty is a state of cumulative degeneration of bodily functions that is consistently associated with poor outcomes in older people following illness. Combined stroke intervention and frailty may yield additive and synergistic effects adults with stroke. OBJECTIVE: To evaluate the safety and efficacy of endovascular therapy (EVT) in frail patients. METHODS: We conducted a systematic review of the relationship between debilitation and acute ischemic stroke (AIS) after EVT...
March 25, 2023: Aging Clinical and Experimental Research
Elisabetta Tonet, Andrea Raisi, Silvia Zagnoni, Giorgio Chiaranda, Rita Pavasini, Francesco Vitali, Federico Gibiino, Roberta Campana, Alberto Boccadoro, Antonella Scala, Luca Canovi, Veronica Amantea, Camilla Matese, Maria Letizia Berloni, Tommaso Piva, Valentina Zerbini, Laura Sofia Cardelli, Giovanni Pasanisi, Gianni Mazzoni, Gianni Casella, Giovanni Grazzi, Gianluca Campo
BACKGROUND: Traditional cardiac rehabilitation (CR) is effective in improving physical performance and prognosis after myocardial infarction (MI). Anyway, it is not consistently recommended to older adults, and its attendance rate is low. Previous studies suggested that alternative, early and tailored exercise interventions are feasible and effective in improving physical performance in older MI patients. Anyway, the demonstration that they are associated also with a significant reduction of hard endpoints is lacking...
March 25, 2023: Aging Clinical and Experimental Research
Lorenzo Lippi, Alessio Turco, Arianna Folli, Francesco D'Abrosca, Claudio Curci, Kamal Mezian, Alessandro de Sire, Marco Invernizzi
BACKGROUND: Several technological advances and digital solutions have been proposed in the recent years to face the emerging need for tele-monitoring older adults with Chronic Obstructive Pulmonary Disease (COPD). However, several challenges have negatively influenced an evidence-based approach to improve Health-Related Quality of Life (HR-QoL) in these patients. AIM: To assess the effects of tele-monitoring devices on HR-QoL in older adults with COPD. METHODS: On November 11, 2022, PubMed, Scopus, Web of Science, and Cochrane were systematically searched for randomized controlled trials (RCTs) consistent with the following PICO model: older people with COPD as participants, tele-monitoring devices as intervention, any comparator, and HR-QoL as the primary outcome...
March 23, 2023: Aging Clinical and Experimental Research
Selina Malouka, Alexandra Jean Mayhew, Hon Yiu So, Parminder Raina, Marla Beauchamp, Julie Richardson, Ayse Kuspinar
BACKGROUND: The Life-Space Assessment (LSA) can compliment traditional physical performance measures of mobility by accounting for the interaction between individuals and their environment. However, there are no studies that have generated percentile curves showing sex-stratified reference values in a large population-based sample of community-dwelling adults, making its interpretation difficult. Therefore, this study aimed to establish sex-stratified reference values for the LSA in middle-aged and older Canadians...
March 22, 2023: Aging Clinical and Experimental Research
M Cristina Polidori, Luigi Ferrucci
No abstract text is available yet for this article.
March 22, 2023: Aging Clinical and Experimental Research
Anna Nivestam, Albert Westergren, Maria Haak
BACKGROUND AND AIM: To inform health promotion interventions, there is a need for large studies focusing specifically on what makes older adults feel good, from their own perspective. The aim was to explore older adults' views of what makes them feel good in relation to their different characteristics. METHODS: A qualitative and quantitative study design was used. Independently living people (n = 1212, mean age 78.85) answered the open-ended question, 'What makes you feel good?' during preventive home visits...
March 20, 2023: Aging Clinical and Experimental Research
Ursula Müller-Werdan, M Cristina Polidori, Andreas Simm
The COVID-19 pandemic is a burden for the worldwide healthcare systems. Whereas a clear age-dependent mortality can be observed, especially multimorbid and frail persons are at an increased risk. As bio-functional rather than calendrical age is in the meanwhile known to play a crucial role for COVID-19-related outcomes, aging-associated risk factors, overall prognosis and physiological age-related changes should be systematically considered for clinical decision-making. In this overview, we focus on cellular senescence as a major factor of biological aging, associated with organ dysfunction and increased inflammation (inflammaging)...
March 20, 2023: Aging Clinical and Experimental Research
Liza De Dobbeleer, Myrthe Manouk Swart, Merle Anne Joëlle Geerds, Remco Johan Baggen, Anne-Jet Sophie Jansen, Rudi Tielemans, Hugo Silva, Siddhartha Lieten, Kurt Barbé, Geeske Peeters, Miriam Marie Rose Vollenbroek-Hutten, René Johannes Franciscus Melis, Ivan Bautmans
INTRODUCTION: We developed Eforto®, an innovative system for (self-)monitoring of grip strength (GS) and muscle fatigability (Fatigue Resistance (FR = time until GS decreased to 50% of maximum during sustained contraction) and grip work (GW = area under the strength-time curve)). The Eforto® system consists of a rubber bulb that is wirelessly connected to a smartphone-based application, and a telemonitoring platform. The aim was to evaluate the validity and reliability of Eforto® to measure muscle fatigability...
March 10, 2023: Aging Clinical and Experimental Research
Alessandra Marengoni, Agnese Cangini, Andrea Pierantozzi, Graziano Onder, Roberto Da Cas, Ilaria Ippoliti, Simona Zito, Francesco Trotta
No abstract text is available yet for this article.
March 10, 2023: Aging Clinical and Experimental Research
Chiara Ceolin, Giulia Bano, Carlo Biz, Marta Dianin, Marco Bedogni, Aurelio Guarnaccia, Antonio Berizzi, Pietro Ruggieri, Alessandra Coin, Giuseppe Sergi
BACKGROUND: Proximal femur fractures have a negative impact on loss of functional autonomy and mortality. OBJECTIVE: The aim of this retrospective study was to evaluate functional autonomy and mortality in a group of older adults with hip fractures managed in an orthogeriatric setting 12 months after discharge and to determine if gender affected outcome. METHODS: In all participants, we assessed clinical history, functional pre-fracture status using activities of daily living (ADL) and in-hospital details...
March 9, 2023: Aging Clinical and Experimental Research
Tomoyuki Kawada
No abstract text is available yet for this article.
March 7, 2023: Aging Clinical and Experimental Research
Juan Xu, Yu-Xiang Guan, Wen-Tao Liu, Ying Zhang, Jing Zheng, Jing Zhang, Chao Wang, Fei Yang, Qing Yang
BACKGROUND: The purpose of this scoping review was to organize and describe the literature on the application of clown care to the elderly population in nursing homes, including intervention time, intervention methods and intervention effects, so as to provide reference ideas for other scholars to explore clown care programs suitable for the elderly population in nursing homes. METHODS: Employing Arksey and O'Malley's methodology, we searched for PubMed, Web of Science, Embase, Cochrane, CNKI, WanFang, VIP, and CBM systematically and thoroughly, and the search period was from the establishment of each database to December 12, 2022...
March 6, 2023: Aging Clinical and Experimental Research
Li Xi, Zhong Xuemei, Yan Ling, Chen Changchun, Hou Zhuo, Qin Jinyang, Wei Xin
OBJECTIVE: This study aims to accurately evaluate the cardiac structure and function of the frail population in elderly patients with normal ejection fraction (EF) using the 3D volume quantification and speckle tracking of echocardiography, to explore the correlation between frailty and cardiac structure and function. METHODS: A total of 350 elderly aged 65 and above in-patients, excluding those with congenital heart disease, cardiomyopathy, and severe valvular heart disease, were included in the study...
March 5, 2023: Aging Clinical and Experimental Research
Salvatore Chirumbolo
No abstract text is available yet for this article.
March 4, 2023: Aging Clinical and Experimental Research
Diana Petrosyan, Maria M Corrada, Claudia H Kawas, Asmeret Demoz, Czarina Ganzon, Oksana Popovich, Reham Gaied, Dan Mungas, Paola Gilsanz, Katharine E Vieira, Rachel A Whitmer, Charles DeCarli
BACKGROUND: Though dementia rates vary by racial or ethnic groups, it is unknown if these disparities remain among those aged 90 or older. AIMS: To test this hypothesis, we used baseline clinical evaluation of 541 ethnically and racially diverse individuals participating in the LifeAfter90 Study to assess how associations between core demographic characteristics and measures of physical and cognitive performance differ across the racial/ethnic groups. METHODS: Participants in this study were long-term non-demented members of Kaiser Permanente Northern California...
March 4, 2023: Aging Clinical and Experimental Research
Katsunari Sato, Akira Ochi, Kazuko Watanabe, Kazumasa Yamada
BACKGROUND: Some patients with minor cognitive impairment can revert to normal cognition if intervention is implemented early. Dance video games as multi-task training have shown beneficial effects on cognitive and physical functions in older adults. AIMS: This study aimed to elucidate the effects of dance video game training on cognitive functions and prefrontal cortex activity in older adults with and without mild cognitive impairment. METHODS: A single-arm trial was used for this study...
March 3, 2023: Aging Clinical and Experimental Research
Pascal Thibon, Carine Grenier, Stéphane Erouart, France Borgey, Simon Le Hello, Mélanie Martel
BACKGROUND: Older adults living in nursing homes (NH) paid a heavy price to the COVID-19 pandemic, despite early and often drastic prevention measures. AIMS: To study the characteristics and the impact of the pandemic on NH residents and professionals over 2 years. METHODS: Cross-sectional study of COVID-19 clusters among residents and/or professionals in NH, from March 2020 to February 2022, in Normandy, France. We used data from the French mandatory reporting system, and cross-correlation analysis...
March 2, 2023: Aging Clinical and Experimental Research
Betül Kuş, Funda Büyükyılmaz, Aysun Ardıç
BACKGROUND: As a result of falls, older patients experience injury and loss of function, and their length of hospital stay and care costs increase. AIM: This study was conducted to determine fall risks and compare the sensitivity and specificity of three fall risk assessment tools. METHODS: Older patients' fall risk levels were determined according to the Itaki, Hendrich-II, and Morse tools within 2 h following their admission to the wards...
March 1, 2023: Aging Clinical and Experimental Research
Mohamad El Haj, Ahmed A Moustafa, Frédérique Robin, Guillaume Chapelet
BACKGROUND: Associative inference refers to an adaptive ability that allows flexible recombination of information acquired during previous experiences to make new connections that they have not directly experienced. This cognitive ability has been widely associated with the hippocampus. AIMS: We investigated associative inference in patients with Alzheimer's disease and control participants. METHODS: The task has two phases. In the training phase, participants learned to encode overlapping pairs of objects (AB + BC)...
February 28, 2023: Aging Clinical and Experimental Research
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