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International Journal of MS Care

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https://read.qxmd.com/read/30568569/guest-editorial-shared-decision-making-in-managing-multiple-sclerosis-revisiting-the-research-agenda
#1
EDITORIAL
Christoph Heesen, Anne Christin Rahn
No abstract text is available yet for this article.
November 2018: International Journal of MS Care
https://read.qxmd.com/read/30568568/2018-ijmsc-reviewer-acknowledgment
#2
(no author information available yet)
No abstract text is available yet for this article.
November 2018: International Journal of MS Care
https://read.qxmd.com/read/30568567/poster-abstracts-from-the-eighth-international-symposium-on-gait-and-balance-in-multiple-sclerosis-exercise-symptom-management-to-disease-modification-world-trade-center-%C3%A2-portland-oregon-usa-%C3%A2-september-15-2018
#3
https://read.qxmd.com/read/30568566/impact-of-shared-decision-making-on-disease-modifying-drug-adherence-in-multiple-sclerosis
#4
Aliza Ben-Zacharia, Meagan Adamson, Allison Boyd, Paula Hardeman, Jennifer Smrtka, Bryan Walker, Tracy Walker
Background: Shared decision making (SDM) and adherence to treatment are an integral part of multiple sclerosis (MS) care. A collaborative process, SDM actively involves the patient, the health care provider, and an extended network in making treatment decisions. Adherence to disease-modifying drug therapies in patients with MS presents an ongoing challenge for patients and health care providers due to the chronic nature of this disease. This narrative review aims to explore the impact of SDM on adherence based on existing literature and to identify new approaches to optimizing adherence...
November 2018: International Journal of MS Care
https://read.qxmd.com/read/30568565/from-medical-prescription-to-patient-compliance-a-qualitative-insight-into-the-neurologist-patient-relationship-in-multiple-sclerosis
#5
Vincent Schlegel, Emmanuelle Leray
Background: Approximately 12 disease-modifying treatments are available worldwide for patients with relapsing multiple sclerosis (MS). These recent therapeutic advances have led to major changes in patient and neurologist attitudes toward drug prescription. Herein, we aimed to characterize patient choice regarding treatment for MS and identify how neurologists assess and monitor patient compliance during follow-up. Methods: In 29 patients with MS, we observed visits to their neurologist to understand how questions related to compliance were addressed in the doctor-patient relationship...
November 2018: International Journal of MS Care
https://read.qxmd.com/read/30568564/perspectives-of-patients-with-multiple-sclerosis-on-drug-treatment-a-qualitative-study
#6
Larry D Lynd, Natalie J Henrich, Celestin Hategeka, Carlo A Marra, Nicole Mittmann, Charity Evans, Anthony L Traboulsee
Background: Patients experience multiple sclerosis (MS) differently based on their disease type and other factors. This study aimed to explore the relative importance that patients with MS place on various attributes of MS drug therapies and to elucidate these patients' preferences regarding treatment characteristics such as administration, potential benefits, and side effects of the therapies. Methods: Focus groups were conducted in Vancouver, Canada, with 23 adult patients with MS...
November 2018: International Journal of MS Care
https://read.qxmd.com/read/30568563/evaluation-of-a-novel-preference-assessment-tool-for-patients-with-multiple-sclerosis
#7
Nananda F Col, Andrew J Solomon, Vicky Springmann, Carolina Ionete, Enrique Alvarez, Brenda Tierman, Christen Kutz, Idanis Berrios Morales, Carolyn Griffin, Long H Ngo, David E Jones, Glenn Phillips, Ashli Hopson, Lori Pbert
Background: We developed a preference assessment tool to help assess patient goals, values, and preferences for multiple sclerosis (MS) management. All preference items in the tool were generated by people with MS. The aim of this study was to evaluate this tool in a national sample of people with MS. Methods: English-speaking patients with MS aged 21 to 75 years with access to the internet were recruited. Participants completed the preference tool online, which included separate modules assessing three core preference areas: treatment goals, preferences for attributes of disease-modifying therapies, and factors influencing a change in treatment...
November 2018: International Journal of MS Care
https://read.qxmd.com/read/30568562/associations-between-treatment-satisfaction-medication-beliefs-and-adherence-to-disease-modifying-therapies-in-patients-with-multiple-sclerosis
#8
Andrew V Thach, Carolyn M Brown, Vivian Herrera, Rahul Sasane, Jamie C Barner, Kentya C Ford, Kenneth A Lawson
Background: Adherence to disease-modifying therapy (DMT) remains problematic for many patients with multiple sclerosis (MS). An improved understanding of factors affecting DMT adherence may inform effective interventions. This study examined associations between treatment satisfaction, medication beliefs, and DMT adherence. Methods: A survey was mailed in 2016 to 600 adult patients with relapsing-remitting MS taking an injectable or oral DMT. Patients were sampled from the North American Research Committee on Multiple Sclerosis (NARCOMS) Registry...
November 2018: International Journal of MS Care
https://read.qxmd.com/read/30374256/editorial
#9
EDITORIAL
Francois Bethoux
No abstract text is available yet for this article.
September 2018: International Journal of MS Care
https://read.qxmd.com/read/30374255/total-hip-and-knee-arthroplasty-in-patients-with-multiple-sclerosis
#10
Josef Maxwell Gutman, Kelvin Kim, Ran Schwarzkopf, Ilya Kister
Background: Hip and knee replacements for osteoarthritis are established procedures for improving joint pain and function, yet their safety in patients with multiple sclerosis (MS) is unknown. Patients with MS face unique surgical challenges due to underlying neurologic dysfunction. Current literature on arthroplasty in MS is limited to case reports focusing on adverse events. Methods: Of 40 identified patients who underwent hip or knee replacement, 30 had sufficient data for inclusion...
September 2018: International Journal of MS Care
https://read.qxmd.com/read/30374254/-case-report-combining-dalfampridine-with-multicomponent-exercise-and-gait-training-in-a-person-with-multiple-sclerosis
#11
Prudence Plummer, Corinne J Bohling, L Ellese Nickles, Alexis A Williams, Amy Thomas, Silva Markovic-Plese, Barbara Giesser
Background: Dalfampridine extended release (D-ER) improves gait speed in some people with multiple sclerosis (MS), but many patients who take D-ER demonstrate only small improvements of questionable clinical significance. Physical therapy (PT) may augment the treatment effects of D-ER on the nervous system and improve clinical outcomes. This case report describes the successful use of D-ER combined with multicomponent PT in a patient who did not have a clinically important change in gait speed with D-ER alone...
September 2018: International Journal of MS Care
https://read.qxmd.com/read/30374253/test-retest-reliability-validity-and-minimal-detectable-change-of-the-balance-evaluation-systems-test-to-assess-balance-in-persons-with-multiple-sclerosis
#12
Kathryn D Mitchell, Han Chen, Sheri P Silfies
Background: Individuals with multiple sclerosis (MS) have balance deficits that result in falls. Balance tests developed for older adults do not discriminate between fallers and nonfallers with MS. The Balance Evaluation Systems Test (BESTest) identifies body systems contributing to imbalance/fall risk. This study evaluated the test-retest reliability and construct validity of the BESTest to assess balance in individuals with MS, compared the diagnostic accuracy of the BESTest and Berg Balance Scale (BBS), and investigated the minimal detectable change of the BESTest in this population...
September 2018: International Journal of MS Care
https://read.qxmd.com/read/30374252/five-year-follow-up-of-a-longitudinal-cohort-study-of-the-effectiveness-of-functional-electrical-stimulation-for-people-with-multiple-sclerosis
#13
Tamsyn Street, Christine Singleton
Background: Few studies have examined the long-term consequences of using peroneal nerve functional electrical stimulation (FES) for people with multiple sclerosis (MS). This study examines orthotic effects on a longitudinal cohort and explores additional benefits of FES on self-reported measures such as joint pain. Methods: One hundred forty-five people with foot drop and MS were included (mean age, 52 [range, 28-74] years). Orthotic effects, unassisted walking speed, and clinically important differences (ie, ≥0...
September 2018: International Journal of MS Care
https://read.qxmd.com/read/30374251/upper-limb-intention-tremor-in-multiple-sclerosis-an-evidence-based-review-of-assessment-and-treatment
#14
J Keiko McCreary, James A Rogers, Susan J Forwell
Background: To present the current knowledge on the characteristics, assessment, and treatment of upper limb intention tremor to inform and improve future intervention studies in patients with multiple sclerosis (MS), we conducted a literature review for articles on upper limb intention tremor in patients with MS. Methods: Two reviewers conducted searches in PubMed, Web of Science, and MEDLINE (Ovid). Relevant articles, sorted on inclusion criteria, were examined for descriptions and assessments of upper limb intention tremor, and intervention studies were evaluated based on treatment type...
September 2018: International Journal of MS Care
https://read.qxmd.com/read/30374250/effects-of-rehabilitation-on-gait-pattern-at-usual-and-fast-speeds-depend-on-walking-impairment-level-in-multiple-sclerosis
#15
Carmela Leone, Alon Kalron, Tori Smedal, Britt Normann, Inez Wens, Bert O Eijnde, Peter Feys
Background: Physical rehabilitation can improve walking capacity in persons with multiple sclerosis (MS). However, changes in spatiotemporal gait parameters after rehabilitation are not frequently evaluated, and it is unknown to what extent potential effects depend on baseline disability level. The objective was to investigate the effectiveness of rehabilitation programs on gait parameters at usual and fastest speeds in persons with MS categorized according to walking speed. Methods: This nonrandomized multinational study in "real-world" settings evaluated participants before and after conventional rehabilitation...
September 2018: International Journal of MS Care
https://read.qxmd.com/read/30150905/editorial
#16
EDITORIAL
Francois Bethoux
No abstract text is available yet for this article.
July 2018: International Journal of MS Care
https://read.qxmd.com/read/30150904/factors-associated-with-sexual-dysfunction-in-individuals-with-multiple-sclerosis-implications-for-assessment-and-treatment
#17
Samantha Domingo, Tyler Kinzy, Nicolas Thompson, Shauna Gales, Lael Stone, Amy Sullivan
Background: Sexual dysfunction is a common symptom of multiple sclerosis (MS) that often goes unreported by both the patient and the clinician. Sexual dysfunction can affect a person's mood, relationships, daily functioning, and quality of life. Gaining a better understanding of the prevalence and nature of sexual dysfunction in individuals with MS would not only help identify patients with this problem but also determine contributing factors, which can inform treatment alternatives available to the patient...
July 2018: International Journal of MS Care
https://read.qxmd.com/read/30150903/-case-report-effect-of-antigravity-treadmill-training-on-muscle-oxidative-capacity-muscle-endurance-and-walking-function-in-a-person-with-multiple-sclerosis
#18
T Bradley Willingham, Jonathan Melbourn, Marina Moldavskiy, Kevin K McCully, Deborah Backus
Background: Exercise training can improve skeletal muscle metabolism in persons with multiple sclerosis (MS). However, quantification of exercise-mediated improvements in muscle metabolism has been limited, particularly in people with high levels of disability. We evaluated the effect of 9 weeks of antigravity treadmill training on muscle oxidative capacity and muscle endurance and assessed the relationship to walking function in a person with MS. Methods: One person with MS (Expanded Disability Status Scale score, 6...
July 2018: International Journal of MS Care
https://read.qxmd.com/read/30150902/-case-report-rapid-eye-movement-sleep-behavior-disorder-as-the-first-manifestation-of-multiple-sclerosis-a-case-report-and-literature-review
#19
Alejandro Enriquez-Marulanda, Valentina Quintana-Peña, Yuri Takeuchi, Jairo Quiñones
Rapid eye movement sleep behavior disorder (RBD) is a parasomnia characterized by brief recurrent episodes of loss of muscle atonia during rapid eye movement sleep, with enacted dreams that cause sleep disruption. Patients with multiple sclerosis (MS) have an increased risk compared with the general population to be affected by a sleep disturbance, including RBD. Patients affected, however, uncommonly can present RBD as the first clinical manifestation of MS without other neurologic deficits. These clinical presentations have usually been attributed to inflammatory lesions in the pedunculopontine nuclei, located in the dorsal pons...
July 2018: International Journal of MS Care
https://read.qxmd.com/read/30150901/longitudinal-stability-of-cognition-in-early-phase-relapsing-remitting-multiple-sclerosis-does-cognitive-reserve-play-a-role
#20
Roxana M Barbu, Jason A Berard, Louise M Gresham, Lisa A S Walker
Background: Up to 70% of people with multiple sclerosis (MS) experience cognitive impairment. Some remain cognitively intact despite advanced disease. Cognitive reserve (CR) theory postulates that individuals with higher levels of intellectual enrichment can tolerate more pathology than others before exhibiting cognitive impairment. Methods: Thirty-two individuals with early-phase relapsing-remitting MS with mild physical disability and disease duration less than 10 years and 32 controls were recruited...
July 2018: International Journal of MS Care
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