Dyah Noviana Primasari, Intan Nirwana, Hendrik Setia Budi, Agung Satria Wardhana, Annisa Fitria Sari, Novita Novita, Andika Putri Setyawan, Meircurius Dwi Condro Surboyo, Khairul Anuar Shariff
OBJECTIVE: Ellagic acid, a phenolic compound with anti-inflammatory potential, can be used to accelerate the bone healing process and affect human health, while hydroxyapatite is the most commonly used bone graft material. Using a combination of the two materials results in reduced inflammation and increased osteogenesis. This study aimed to determine the effects of combining ellagic acid and hydroxyapatite in bone marker remodelling by analysing the expression of tumour necrosis factor- α (TNF- α ), interleukin 10 (IL-10), bone morphogenetic 4 protein (BMP-4), and osteopontin (OPN)...
2022: TheScientificWorldJournal