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Malaysian Journal of Medical Sciences: MJMS

Masoud Keikha
No abstract text is available yet for this article.
February 2018: Malaysian Journal of Medical Sciences: MJMS
Ramasamy Chidambaram
No abstract text is available yet for this article.
February 2018: Malaysian Journal of Medical Sciences: MJMS
Karan Manoj Anandpara, Yashant Aswani, Priya Hira
Cryptococcosis is a life-threatening mycosis typically seen in immunocompromised patients. Pulmonary cryptococcosis generally presents as multiple or solitary nodular opacities. Cryptococcal infection presenting as a destructing cavernoma (cryptococcoma) without diffuse infiltration of the lung is an extremely rare presentation, even in immunocompromised patients. This report presents a healthy, HIV negative, immunocompetent patient who presented with a large solitary lung mass provisionally diagnosed as a lung malignancy on radiological imaging that proved to be a large cryptococcoma after biopsy...
February 2018: Malaysian Journal of Medical Sciences: MJMS
Jingli Zhang, Fatin H Mohamad, Jia Hui Wong, Habsah Mohamad, Abdul Hadi Ismail, Abdul Aziz Mohamed Yusoff, Hasnah Osman, Kok Tong Wong, Zamzuri Idris, Jafri Malin Abdullah
Background: Bamboo shoot has been used as a treatment for epilepsy in traditional Chinese medicine for generations to treat neuronal disorders such as convulsive, dizziness and headaches. 4-hydroxybenzoic acid (4-hba) is a non-flavonoid phenol found abundantly in Dendrocalamus asper shoots (bamboo), fruits (strawberries and apples) and flowers. Kv1.4 is a rapidly inactivating Shaker -related member of the voltage-gated potassium channels with two inactivation mechanisms; the fast N-type and slow C-type...
February 2018: Malaysian Journal of Medical Sciences: MJMS
Soumendra Sahoo, Thanigasalam Thevi, Htoo Htoo Kyaw Soe
The purpose of this study was to determine the association of well-being and cognitive impairment with primary open angle glaucoma (POAG) patients attending a tertiary care hospital in Malaysia. Fifty-four individuals were recruited for study as cases were matched with 60 individuals as the control subjects, and data were collected using the WHO well-being index and the validated 6-item cognitive impairment test dementia test. The results showed that there was no significant association between gender, ethnicity, socioeconomic status and POAG...
February 2018: Malaysian Journal of Medical Sciences: MJMS
Zaleha Jusoh, Hizlinda Tohid, Khairani Omar, Noor Azimah Muhammad, Saharuddin Ahmad
Background: The quality of life (QoL) describes the multidimensional self-perceived well-being of a person, which is an important diabetes outcome. This study aimed to measure the QoL scores among patients with type 2 diabetes mellitus (T2DM), as well as their clinical and sociodemographic predictors. Methods: This cross-sectional study involved 180 randomly sampled patients at a primary care clinic on the East Coast of Peninsular Malaysia. A self-administered questionnaire containing the Audit of Diabetes Dependent Quality of Life-18 (ADDQoL-18) was used...
February 2018: Malaysian Journal of Medical Sciences: MJMS
Dwita Oktaria, Diantha Soemantri
Background: The concept of feedback-seeking behaviour has been widely studied, but there is still a lack of understanding of this phenomenon, specifically in an Indonesian medical education setting. The aim of this research was to investigate medical students' feedback-seeking behaviour in depth in one Indonesian medical school. Methods: A qualitative method was employed to explore the feedback-seeking behaviour of undergraduate medical students in the Faculty of Medicine at Universitas Lampung...
February 2018: Malaysian Journal of Medical Sciences: MJMS
Kitchana Kaewkaen, Phongphat Wongsamud, Jiratchaya Ngaothanyaphat, Papawarin Supawarapong, Suraphong Uthama, Worasak Ruengsirarak, Suthin Chanabun, Pratchaya Kaewkaen
Background: The walking gait of older adults with balance impairment is affected by dual tasking. Several studies have shown that external cues can stimulate improvement in older adults' performance. There is, however, no current evidence to support the usefulness of external cues, such as audio-visual cueing, in dual task walking in older adults. Thus, the aim of this study was to investigate the influence of an audio-visual cue (simulated traffic light) on dual task walking in healthy older adults and in older adults with balance impairments...
February 2018: Malaysian Journal of Medical Sciences: MJMS
Fauzi Rosuzeita, Mohamed Che Rabiaah, Ismail Rohani, Othman Mohd Shukri
Background: In Malaysia, the rates of mothers practising breastfeeding exclusively among babies at six months of age still do not achieve the Global Nutritional Targets 2025 which is 50%. Objective: To determine the effectiveness of breastfeeding intervention in improving breastfeeding outcomes. Method: A quasi-experimental design was used involving a purposive sample of 96 primigravidas (intervention group (IG) = 48, control group (CG) = 48) recruited at Hospital USM...
February 2018: Malaysian Journal of Medical Sciences: MJMS
Bachok Norsa'adah, Che' Muda Che-Muzaini
Background: Approximately 5%-10% of acute coronary syndrome (ACS) cases occur in people younger than 45 years of age. This study aimed to identify complications of ACS and the associated factors in young patients. Methods: In this cross-sectional study, data from 147 ACS patients aged less than 45 years were analysed. Results: The mean age was 39.1 (4.9) years, the male to female ratio was 3:1; 21.2% of patients presented with unstable angina, 58...
February 2018: Malaysian Journal of Medical Sciences: MJMS
Lai Chuang Chee, Johari Adnan Siregar, Abdul Rahman Izani Ghani, Zamzuri Idris, Noor Azman A Rahman Mohd
Background: Ruptured cerebral aneurysm is a life-threatening condition that requires urgent medical attention. In Malaysia, a prospective study by the Umum Sarawak Hospital, Neurosurgical Center, in the year 2000-2002 revealed an average of two cases of intracranial aneurysms per month with an operative mortality of 20% and management mortality of 25%. Failure to diagnose, delay in admission to a neurosurgical centre, and lack of facilities could have led to the poor surgical outcome in these patients...
February 2018: Malaysian Journal of Medical Sciences: MJMS
Wan Mohd Nazaruddin Wan Hassan, Hai Siang Tan, Rhendra Hardy Mohamed Zaini
Background: The study aimed to determine the effects of dexmedetomidine on the induction of anaesthesia using different models (Marsh and Schnider) of propofol target-controlled infusion (TCI). Methods: Sixty-four patients aged 18-60 years, American Society of Anaesthesiologists (ASA) class I-II who underwent elective surgery were randomised to a Marsh group ( n = 32) or Schnider group ( n = 32). All the patients received a 1 μg/kg loading dose of dexmedetomidine, followed by TCI anaesthesia with remifentanil at 2 ng/mL...
February 2018: Malaysian Journal of Medical Sciences: MJMS
Azam Moslehi, Mohsen Farahabadi, Sayyed Abdollah Chavoshzadeh, Akram Barati, Shima Ababzadeh, Abolfazl Mohammadbeigi
Background: Endoplasmic reticulum (ER) stress creates abnormalities in the insulin action, inflammatory responses, lipoprotein B100 degradation, and hepatic lipogenesis. Hepatic steatosis leads to a broad spectrum of hepatic disorders such as nonalcoholic fatty liver disease (NAFLD) and NASH. Amygdalin has beneficial effects on asthma, bronchitis, diabetes, and atherosclerosis. We designed this study to evaluate the effect of amygdalin on the ER stress induced hepatic steatosis. Methods: Inbred mice received saline, DMSO and amygdalin, as control groups...
February 2018: Malaysian Journal of Medical Sciences: MJMS
Aidy Irman Yajid, Husna Syakirah Ab Rahman, Michael Pak Kai Wong, Wan Zainira Wan Zain
The incidence of cancer is increasing each year, which generates concerns regarding the efficacy of the current treatment options. This has caused patients to seek alternatives to complement or to replace surgery, chemotherapy and radiotherapy. Annona muricata and other plants have been shown to have promising compounds that can be utilised in the treatment of cancer. Native to the tropical and subtropical parts of the world, A. muricata plant extracts contain compounds that are particularly effective against cancer cells...
February 2018: Malaysian Journal of Medical Sciences: MJMS
Zamzuri Idris, Regunath Kandasamy, Yee Yik Neoh, Jafri Malin Abdullah, Wan Mohd Nazaruddin Wan Hassan, Mohd Erham Mat Hassan
World-renowned neurosurgeon, Professor Saleem Abdulrauf, has been featured in several medical journals for his successful "Awake Brain Aneurysm Surgery". Regarded as a "world first", this surgery, involves clipping un-ruptured brain aneurysms while patients are awake. Only one or two neurosurgery centres worldwide are capable of this. Performing the surgery while the patient is awake lowers risks of brain ischemia with neurological deficits and ventilator associated morbidities. The technique has been viewed as the start of a new era in brain surgery...
February 2018: Malaysian Journal of Medical Sciences: MJMS
Kanmani Devi Ganison, Mohammad Saffari Mohammad Haspani, Norzaini Rose Mohd Zain
No abstract text is available yet for this article.
December 2017: Malaysian Journal of Medical Sciences: MJMS
Arvin Rajadurai, Aida Abdul Aziz, Noor Aida Mat Daud, Abdul Fatah Abdul Wahab, Ahmad Sobri Muda
Introduction: Venous aneurysms are not as common as their arterial counterpart. The choice of management is debatable. Case Report: We present the case of a teenage boy with left external jugular vein aneurysm treated by endovascular technique. Embolisation was done using pushable microcoils with access via the femoral vein and direct puncture. Conclusion: This form of treatment provides a less-invasive option with a more concrete evaluation of the venous abnormality and its drainage during venous aneurysm occlusion...
December 2017: Malaysian Journal of Medical Sciences: MJMS
Tarun Ralot, Chander Bafna, Surender Singh, Shubhkaran Sharma
Persistent neutrophilic meningitis is an atypical form of chronic meningitis defined as clinical meningitis with a cerebrospinal fluid (CSF) analysis suggestive of neutrophilic pleocytosis that persists for more than one week despite giving empirical antimicrobial therapy. The predominant presentation of tubercular meningitis is with CSF lymphocytic pleocytosis and even if early phase of the disease presents with neutrophilic pleocytosis, no persistence is usually observed for more than one week. We hereby report the case of an immunocompetent man aged 25 years with tubercular meningitis manifesting as persistent neutrophilic meningitis which is very rare as an entity in tubercular meningitis (TBM)...
December 2017: Malaysian Journal of Medical Sciences: MJMS
Ang Song Yee, John Tharakan, Zamzuri Idris, Shalini Bhaskar, Sanihah Abdul Halim, Salmi Abd Razak, Zabidi Azhar Mohd Hussin, Regunath Kandasamy, Wan Mohd Nazaruddin Wan Hassan, Laila Mukmin, Mohamad Hasyizan Hassan, Tan Yew Chin, Badrisyah Idris, Abdul Rahman Izaini Ghani, Hillol Kanti Pal, Jain George, Sani Sayuthi, Mohamed Saufi Awang, Jafri Malin Abdullah
Epilepsy surgery has been performed by a few centres in Malaysia, including Hospital Universiti Sains Malaysia (HUSM). To date, a total of 15 patients have undergone epilepsy surgery in HUSM. The epilepsy surgery included anterior temporal lobectomy (ATL) with amygdalohippocampectomy (AH) and Vagal nerve stimulation (VNS). The surgical outcomes of the patients were assessed using the International League Against Epilepsy (ILAE) outcome scale. The ILAE scores for patients who underwent ATL with AH were comparatively better than those who underwent VNS...
December 2017: Malaysian Journal of Medical Sciences: MJMS
Yusrita Zolkefli
Choice is what we all want, as most would say. There is a growing cognisance that patients can and should play an important role in deciding their own care, in defining optimal care, and in improving healthcare delivery. Popular concepts such as patient-centred care, patient empowerment, and patients as partners, shared decision making, and informed choice illustrate the emancipation of patient. The paper describes that choice is not necessarily a good thing in health care; however, that does not rebut the significance of choice...
December 2017: Malaysian Journal of Medical Sciences: MJMS
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