Christian P Filss, Julian Cramer, Saskia Löher, Philipp Lohmann, Gabriele Stoffels, Carina Stegmayr, Martin Kocher, Alexander Heinzel, Norbert Galldiks, Hans J Wittsack, Michael Sabel, Bernd Neumaier, Jürgen Scheins, N Jon Shah, Philipp T Meyer, Felix M Mottaghy, Karl-Josef Langen
PURPOSE: Morphological imaging using MRI is essential for brain tumour diagnostics. Dynamic susceptibility contrast (DSC) perfusion-weighted MRI (PWI), as well as amino acid PET, may provide additional information in ambiguous cases. Since PWI is often unavailable in patients referred for amino acid PET, we explored whether maps of relative cerebral blood volume (rCBV) in brain tumours can be extracted from the early phase of PET using O-(2-18 F-fluoroethyl)-L-tyrosine (18 F-FET). PROCEDURE: Using a hybrid brain PET/MRI scanner, PWI and dynamic 18 F-FET PET were performed in 33 patients with cerebral glioma and four patients with highly vascularized meningioma...
October 17, 2023: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging