journal
https://read.qxmd.com/read/38459352/shifts-in-the-clinical-trial-landscape
#21
Asher Mullard
No abstract text is available yet for this article.
March 8, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38459351/gsk-s-first-in-class-antibiotic-secures-another-phase-iii-win-approaches-regulatory-run
#22
Asher Mullard
No abstract text is available yet for this article.
March 8, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38459350/top-companies-and-drugs-by-sales-in-2023
#23
Paul Verdin
No abstract text is available yet for this article.
March 8, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38454144/suppressing-tumour-t-reg-cells-with-a-histone-demethylase-inhibitor
#24
Alex Eccleston
No abstract text is available yet for this article.
March 7, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38448670/making-macrophages-with-anti-tumour-activity
#25
Sarah Crunkhorn
No abstract text is available yet for this article.
March 6, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38448669/targeting-proteins-with-bivalent-glues
#26
Sarah Crunkhorn
No abstract text is available yet for this article.
March 6, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38448668/myc-inhibitor-achieves-phase-i-success
#27
Sarah Crunkhorn
No abstract text is available yet for this article.
March 6, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38448667/increasing-the-potency-of-t-cell-therapies
#28
Sarah Crunkhorn
No abstract text is available yet for this article.
March 6, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38448666/ribosome-targeted-antibiotic-tackles-antimicrobial-resistance
#29
Katie Kingwell
No abstract text is available yet for this article.
March 6, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38448606/the-present-and-future-of-bispecific-antibodies-for-cancer-therapy
#30
REVIEW
Christian Klein, Ulrich Brinkmann, Janice M Reichert, Roland E Kontermann
Bispecific antibodies (bsAbs) enable novel mechanisms of action and/or therapeutic applications that cannot be achieved using conventional IgG-based antibodies. Consequently, development of these molecules has garnered substantial interest in the past decade and, as of the end of 2023, 14 bsAbs have been approved: 11 for the treatment of cancer and 3 for non-oncology indications. bsAbs are available in different formats, address different targets and mediate anticancer function via different molecular mechanisms...
March 6, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38467772/monkeypox-mrna-vaccine-protects-mice-and-macaques
#31
Sarah Crunkhorn
No abstract text is available yet for this article.
March 4, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38429526/from-basic-research-to-budding-biotechs-under-one-roof-with-stuart-schreiber
#32
Asher Mullard
No abstract text is available yet for this article.
March 1, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38418662/therapeutic-developments-for-tuberculosis-and-nontuberculous-mycobacterial-lung-disease
#33
REVIEW
Véronique Dartois, Thomas Dick
Tuberculosis (TB) drug discovery and development has undergone nothing short of a revolution over the past 20 years. Successful public-private partnerships and sustained funding have delivered a much-improved understanding of mycobacterial disease biology and pharmacology and a healthy pipeline that can tolerate inevitable attrition. Preclinical and clinical development has evolved from decade-old concepts to adaptive designs that permit rapid evaluation of regimens that might greatly shorten treatment duration over the next decade...
February 28, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38409339/opportunities-and-challenges-for-innovative-and-equitable-healthcare
#34
David J Ecker, Clarice D Aiello, Joseph R Arron, C Frank Bennett, Amy Bernard, Xandra O Breakefield, Timothy J Broderick, Shawneequa L Callier, Barry Canton, Janice S Chen, C Simone Fishburn, Banning Garrett, Sidney M Hecht, Tobias Janowitz, Melinda Kliegman, Adrian Krainer, Chrystal U Louis, Christopher Lowe, Alfica Sehgal, Yesim Tozan, Kevin J Tracey, Fyodor Urnov, Daniel Wattendorf, Thomas W Williams, Xuanhe Zhao, Michael R Hayden
No abstract text is available yet for this article.
February 26, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38374252/when-can-ai-deliver-the-drug-discovery-hits
#35
Asher Mullard
No abstract text is available yet for this article.
February 19, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38374249/fda-approves-first-tumour-infiltrating-lymphocyte-til-therapy-bolstering-hopes-for-cell-therapies-in-solid-cancers
#36
Asher Mullard
No abstract text is available yet for this article.
February 19, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38336887/the-colorectal-cancer-drug-market
#37
Laura Ramos García, Rachel M Webster
No abstract text is available yet for this article.
February 9, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38321319/the-bespoke-gene-therapy-consortium-facilitating-development-of-aav-gene-therapies-for-rare-diseases
#38
P J Brooks, Timothy M Miller, Frédéric Revah, Junghae Suh, Bradley R Garrison, Lawrence C Starke, Timothy K MacLachlan, Edward G Neilan, Gopa Raychaudhuri, Sadik H Kassim, Jean Dehdashti, Joni L Rutter
No abstract text is available yet for this article.
February 6, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38316949/macrocyclic-peptides-thwart-gram-negative-bacteria
#39
Alex Eccleston
No abstract text is available yet for this article.
February 5, 2024: Nature Reviews. Drug Discovery
https://read.qxmd.com/read/38297092/the-pipeline-and-market-for-psoriasis-drugs
#40
Rami Al-Horani, Thomas Chui, Bashar Hamad
No abstract text is available yet for this article.
January 31, 2024: Nature Reviews. Drug Discovery
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