Matteo Piga, Kostantinos Tselios, Luísa Viveiros, Elisabetta Chessa, Ana Neves, Murray Barry Urowitz, David Isenberg
Systemic lupus erythematosus (SLE) is a complex disease with an insidious clinical presentation. In up to half of the cases, SLE onset is characterized by clinical and serological manifestations that, although specific, are insufficient to fulfill the classification criteria. This condition, called incomplete SLE, could be as challenging as the definite and classifiable SLE and requires to be treated according to the severity of clinical manifestations. In addition, an early SLE diagnosis and therapeutic intervention can positively influence the disease outcome, including remission rate and damage accrual...
February 21, 2024: Best Practice & Research. Clinical Rheumatology