journal
https://read.qxmd.com/read/37996346/editorial-commentary
#1
EDITORIAL
Jerard Seghatchian
No abstract text is available yet for this article.
November 21, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/38008687/therapeutical-apheresis-and-nephrologist-new-and-old-aspects
#2
REVIEW
Ioannis Griveas
The clinical efficacy of therapeutic apheresis is still controversial. We undertook a retrospective review of apheresis treatment to ascertain its safety and efficacy. The therapeutic apheresis consists of a continuously improving therapeutic method for diseases with high mortality and morbidity, especially in cases with poor outcome by using current medications.
November 20, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/38008686/therapeutic-apheresis-in-renal-transplantation-an-update
#3
REVIEW
Christina Melexopoulou, Vassilis Filiopoulos, Smaragdi Marinaki
Therapeutic apheresis (TA) plays a significant role in various aspects of renal transplantation. It has been a necessary preconditioning component in ABO incompatible kidney transplants and an important modality in the removal of anti-human leukocyte antigen (HLA) antibodies both in the context of desensitization protocols that have been developed to allow highly sensitized kidney transplant candidates to be successfully transplanted and as treatment of antibody mediated rejection episodes post transplantation...
November 17, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/38008685/plasma-exchange-in-patients-with-anca-associated-vasculitis
#4
REVIEW
Aglaia Chalkia, Dimitrios Petras
ANCA-associated Vasculitides (AAV) are characterized by small vessel necrotizing inflammation and can present with multisystem organ involvement, including organ/life threatening manifestations of rapidly progressive glomerulonephritis and diffuse alveolar haemorrhage, where immediate and aggressive intervention is needed to prevent further organ damage. Although, the rationale of plasma exchange (PLEX) in AAV is strong, through removing the pathogenic ANCAs; target either myeloperoxidase (MPO) or proteinase 3 (PR3), and other inflammatory molecules, especially in the initiation when the immunosuppressive treatment is no sufficient to prevent the organ damage, overall impact on patient outcomes is not well-established, while the risk of infections seems to be higher in the PLEX-treated patients...
November 17, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37993288/use-of-therapeutical-apheresis-methods-during-pregnancy
#5
REVIEW
Paraskevi Tseke, Petros Tsekes, Ioannis Griveas
This review will focus on the current application of TA in pregnancy and possible aspects for future studies. It seems that scientific interest and field for further research in pregnancy is lately focused in specific removal of pathogens implicated in the physiologic mechanism of pre-eclampsia/HELLP syndrome as well as recurrent pregnancy failure.
November 15, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37978039/therapeutic-apheresis-in-renal-transplantation-an-update
#6
REVIEW
Christina Melexopoulou, Vassilis Filiopoulos, Smaragdi Marinaki
Therapeutic apheresis (TA) plays a significant role in various aspects of renal transplantation. It has been a necessary preconditioning component in ABO incompatible kidney transplants and an important modality in the removal of anti-human leukocyte antigen (HLA) antibodies both in the context of desensitization protocols that have been developed to allow highly sensitized kidney transplant candidates to be successfully transplanted and as treatment of antibody mediated rejection episodes post transplantation...
November 3, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37953206/stem-cells-mobilization-and-collection-in-allogeneic-related-and-unrelated-donors-a-single-center-experience-with-focus-on-plerixafor
#7
REVIEW
Chiara Marcon, Antonella Bertone, Sara Mauro, Rosalba Mestroni, Giulia Battaglia, Umberto Pizzano, Gabriele Facchin, Maria De Martino, Miriam Isola, Francesca Patriarca, Giovanni Barillari, Chiara Savignano
INTRODUCTION: Poor CD34 + cells mobilization in allogeneic donors could affect transplant outcome. In a subgroup of patient mobilization with granulocyte colony-stimulating factor (G-CSF) alone is unsatisfactory, and Plerixafor could be used to enhance CD34 + cells release from bone marrow niche. MATERIALS AND METHODS: We conducted a retrospective single-center, cohort study on healthy allogeneic donors both related and unrelated, treated by Udine Transfusion Center over the last 10 years (2012-2022)...
November 3, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37949806/apheresis-practices-in-india-progress-and-future-scope
#8
JOURNAL ARTICLE
Gopal Kumar Patidar, Hem Chandra Pandey, Rahul Chaurasia
No abstract text is available yet for this article.
October 31, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37923674/guest-editor-s-bio
#9
EDITORIAL
Francesco Lanza
No abstract text is available yet for this article.
October 31, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37926621/connectivity-in-transfusion-medicine-challenges-benefits-and-goals
#10
JOURNAL ARTICLE
Aspen King, Guillem Beltran Arroyos, Nicolas Cellier, Steve Durgacharan, Maria Kerr, Luis Larrea, Marcia Cardoso
Transfusion medicine requires meticulous record keeping from the time a blood donation is made to the time a patient receives a transfusion. As such, blood collection establishments and processing laboratories generate large amounts of data. This data must be managed, analyzed, and visualized appropriately to ensure safety of the blood supply. Today, the use of information technology (IT) solutions for data management in transfusion medicine varies widely between institutions. In this report, blood center professionals describe how they currently use IT solutions to improve their blood processing methods, the challenges they have, and how they envision IT solutions improving transfusion medicine in the future...
October 26, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37925341/first-report-of-successful-treatment-of-chronic-pediatric-tibial-osteomyelitis-and-fracture-using-autologous-platelet-rich-plasma
#11
JOURNAL ARTICLE
Kexuan Qu, Jianxiang Liu, Hao Chen, Lilan Gao, Shuxia Wang, Mengxing Lv
Osteomyelitis is a refractory disease caused by microbial invasion of the bone, leading to destruction of the bone tissue. It is more common in children. Osteomyelitis requires long treatment at high cost and is associated with high rates of recurrence and disability. It can also be complicated by sepsis that, if not treated in time, can result in death. Here, we report the first case of a 10-year-old patient who presented with chronic tibial osteomyelitis complicated with fracture. The patient had received traditional treatment for osteomyelitis for over 14 months without success...
October 24, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37891133/cerebral-and-intestinal-oxygen-saturation-of-different-volumes-of-red-blood-cell-transfusion-in-preterm-infants
#12
JOURNAL ARTICLE
Rong Chen, Shu-Hua Lai, Wen-Long Xiu, Wen-Hong Cai, Zhi-Qin Chen, Ying-Ling Xie
OBJECTIVES: The purpose of this study was to investigate and compare the effects of 20 ml/kg and 15 ml/kg red blood cell transfusion (RBCT) on cerebral and intestinal tissue oxygenation, the number of administered transfusions, and neonatal complications in premature infants with anemia. METHODS: This prospective, randomized, partially blinded observational study investigated anemic neonates of gestational age < 32 weeks (Registration ID: ChiCTR 1,900,026,672)...
October 24, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37925340/the-impact-of-diabetes-mellitus-on-hematopoietic-stem-cell-mobilization-a-single-center-cohort-study
#13
JOURNAL ARTICLE
Serhat Çelik, Leylagül Kaynar, Zeynep Tuğba Güven, Nermin Keni Begendi, Fatma Demir, Muzaffer Keklik, Ali Ünal
BACKGROUND: Factors such as age, underlying hematological disease, chemotherapy and radiotherapy used, and bone marrow infiltration may cause mobilization failure. Several preclinical observed that diabetes mellitus (DM) leads to profound remodeling of the hematopoietic stem cell (HSC) niche, resulting in the impaired release of HSCs. We aim to examine the effect of DM on HSC mobilization and to investigate whether there is a relationship between complications developing in the DM process and drugs used to treat DM and mobilization failure...
October 22, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37996345/efficacy-of-therapeutic-plasma-exchange-in-pediatric-cases-of-acute-liver-failure-as-an-extracorporeal-liver-support-system
#14
JOURNAL ARTICLE
Mohit Chowdhry, Ankita Sharma, Soma Agrawal, Rohit Vohra, Karunesh Kumar, Neerav Goyal, Arun Kumar V, Nameet Jerath, Smita Malhotra, Anupam Sibal, Manoj Mishra
BACKGROUND: Acute liver failure in the pediatric population is often accompanied by deranged metabolism, severe encephalopathy and coagulopathy. A liver transplant is the most viable option for the management of such patients. Therapeutic plasma exchange (TPE) is helpful in improving the liver biochemistry profile, thereby, increasing their likelihood of undergoing a liver transplant METHOD: The study was conducted over a period of 3 years (January 2018 to December 2021). Indications mainly consisted of ALF with hepatic encephalopathy, worsening liver parameters in spite of medical management, and candidacy for undergoing a liver transplant...
October 21, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37940459/evaluation-of-chemiluminescence-immunoassay-as-a-screening-test-for-syphilis-on-blood-donor-samples
#15
JOURNAL ARTICLE
Cherry Gupta, Kshitija Mittal, Ravneet Kaur, Jasbinder Kaur, Tanvi Sood, Gagandeep Kaur, Paramjit Kaur
BACKGROUND AND OBJECTIVE: Global re-emergence of syphilis among blood donors necessitates novel diagnostic and prevention approaches that encourage timely intervention. Thus, the present study was planned to evaluate the efficiency of Chemiluminescence immunoassay (CLIA) as a screening test for syphilis. MATERIAL AND METHODS: This prospective cross-sectional observational study was conducted from October 2021 to September 2022. A total of 344 donors were enrolled by purposive sampling method, including additional 16 donors who were reactive by the Rapid plasma reagin test (RPR) during the study period...
October 21, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37872073/anti-d-alloimmunization-by-asia-type-del-red-blood-cell-units-in-a-d-negative-thai-patient
#16
JOURNAL ARTICLE
Jairak Thongbut, Caroline Bénech, Niramon Phiri, Ploymanee Suwanwootichai, Chutarat Thongpao, Sasitorn Bejrachandra, Pawinee Kupatawintu, Dootchai Chaiwanichsiri, Yann Fichou
BACKGROUND: DEL phenotype is a rare Rh variant that cannot be detected by routine serological typing, and DEL individuals are thus typed D-negative (D-). Anti-D alloimmunization has been reported in "true" D- patients receiving DEL red blood cells (RBCs). CASE PRESENTATION: A 17-year-old, D- Thai male patient suffering from immunodeficiency syndrome with negative antibody screening received RBC units from 17 serological D- donors over a period of seven months due to acute respiratory failure with anemia...
October 20, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37867056/overview-on-novel-strategies-and-current-guidelines-for-hematopoietic-stem-cell-mobilisation-and-collection
#17
EDITORIAL
F Lanza, M Marchetti, B A Zannetti
The success of the autologous stem cell transplantation is strictly related to an adequate hematopoietic stem cell mobilization and collection. The minimum threshold for a successful mobilization is currently defined as 2 × 106 /kg CD34+ cells. However, the optimal stem cell mobilization strategy is still controversial. The availability of plerixafor, a selective and reversible CXCR4 inhibitor, has been associated with an higher use of chemo-free protocols by many centres. In the near future, it is conceivable that artificial intelligence may became more accurate and comprehensive, possibly guiding clinicians in choosing the optimal mobilisation treatment for the various patients undergoing hematopoietic stem cell transplantation...
October 12, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37858399/overcoming-challenges-in-managing-a-high-risk-pregnancy-with-placenta-previa-and-newly-diagnosed-bombay-phenotype
#18
JOURNAL ARTICLE
Tayler A Van Denakker, Kathy Haddaway, Alyssa Cunningham, Karaleigh Leonard, Kristin Darwin, Monica Meeks, Shari M Lawson, Arthur Vaught, Alison Moliterno, Steve M Frank, Aaron Tobian, Elizabeth Crowe, Evan Bloch, Herleen Rai
BACKGROUND: Bombay phenotype is rare and characterized by a lack of H antigen on the surface of red blood cells (RBCs) with naturally occurring anti-H antibodies. The presence of anti-H necessitates the exclusive use of Bombay phenotype RBCs for transfusion. We present a case of a pregnant woman with Bombay phenotype who required urgent cesarean section delivery due to high-risk placenta previa. CASE DESCRIPTION: A 36-year-old G1P0 woman of Indian origin presented at 36 weeks and 4 days gestation for management of a high-risk pregnancy with complete placenta previa...
October 11, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37838564/leukapheresis-for-car-t-cell-production-and-therapy
#19
REVIEW
Ilias Pessach, Arnon Nagler
Chimeric antigen receptor (CAR) T-cell therapy is an effective, individualized immunotherapy, and novel treatment for hematologic malignancies. Six commercial CAR-T cell products are currently approved for lymphatic malignancies and multiple myeloma. In addition, an increasing number of clinical centres produce CAR-T cells on-site, which enable the administration of CAR-T cells on site. The CAR-T cell products are either fresh or cryopreserved. Manufacturing CAR-T cells is a complicated process that begins with leukapheresis to obtain T cells from the patient's peripheral blood...
October 11, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37838563/pharmacoeconomic-issues-in-stem-cell-mobilization
#20
REVIEW
Carlo Lazzaro
BACKGROUND: recently, stem cell mobilization has made dramatic progress, that ended up in an increasing number of aphereses at target for autologous peripheral stem cell transplantation (ASCT). The aim of this research is investigating the cost-effectiveness of stem cell mobilization. METHODS: a narrative review of the literature was carried out, searching for primary contributions written in English and published during 2000-2023 on cost-effectiveness analysis (CEA) of stem cell mobilization in patients entitled to ASCT...
October 10, 2023: Transfusion and Apheresis Science
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