Megan Winner, Amrita Sethi, John M Poneros, Stavros N Stavropoulos, Peter Francisco, Charles J Lightdale, John D Allendorf, Peter D Stevens, Tamas A Gonda
CONTEXT: Molecular analysis of pancreatic cyst fluid obtained by EUS-FNA may increase diagnostic accuracy. We evaluated the utility of cyst-fluid molecular analysis, including mutational analysis of K-ras, loss of heterozygosity (LOH) at tumor suppressor loci, and DNA content in the diagnoses and surveillance of pancreatic cysts. METHODS: We retrospectively reviewed the Columbia University Pancreas Center database for all patients who underwent EUS/FNA for the evaluation of pancreatic cystic lesions followed by surgical resection or surveillance between 2006-2011...
March 20, 2015: JOP: Journal of the Pancreas