Wenhe Luo, Tao Li, Meng Wang, Wanqin Dai, Chunlei Jiao, Yuhui Ma, Yayun Ding, Fang Yang, Xiao He, Zhiyong Zhang
Quantitatively studying the biodistribution and transformation of nanomaterials is of great importance for nanotoxicological evaluation. Recently, laser ablation inductively coupled plasma mass spectrometry has been employed to distinguish nanoparticles (NPs) with their dissolved ions in biological samples. The principle of the proposal is based on a hypothesis that the intact NPs sampled by laser ablation will generate discrete sharp pulses of signals in ICP-MS measurement, being totally different from the continuous, relatively lower signals generated by ions...
November 1, 2021: Journal of Nanoscience and Nanotechnology