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Journal of Musculoskeletal & Neuronal Interactions

Wenkui Sun, Minming Yi, Yang Bai, Lijuan Wu, Jianlin Chen, Yucheng Ren, Xiaoduan Liu, Hongwei Wu, Yao Meng, Qinglian Zhang
OBJECTIVE: To explore the correlations between the polymorphism of the gene first exon +869T/C in transforming growth factor-β1 (TGF-β1) and rheumatoid arthritis (RA). METHODS: The patient group included 150 RA patients at the Department of Rheumatology in the First Affiliated Hospital of Chengdu Medical College between March 2014 and May 2017 and 150 healthy cases as the control group. The polymorphism was analyzed using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and relationships between RA patients and genotypes were analyzed using logistic regression...
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Ioannis D Papanastassiou, Andreas Piskopakis, Maria A Gerochristou, George D Chloros, Olga D Savvidou, Dimitris Issaiades, Panayiotis J Papagelopoulos
No abstract text is available yet for this article.
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Victoria Kougias, Elpis Hatziagorou, Nikolaos Laliotis, Fotis Kyrvasillis, Vasiliki Georgopoulou, John Tsanakas
Myossitis ossificans (MO) is a benign disorder characterized by heterotopic bone formation in skeletal muscle. It is divided in three types, fibrodysplasia ossificans progressive (FOP), myositis ossificans circumscripta or traumatica (MOT) and myositis ossificans without a history of trauma (non traumatic or pseudomalignant MO). Myositis ossificans is extremely rare in children younger than 10 years. We present the clinical and radiological findings of two 5-year-old children with pseudomalignant MO due to prolonged immobilization...
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Elena Segal, Gamal Hassoun, Carcom Maor, Eduardo Shahar
BACKGROUND: HIV infection and antiretroviral therapy (ART) are associated with bone mineral loss. DXA is the gold standard method to evaluate the status of bone mineral density (BMD). However, it is not always readily available. An easy method is needed to evaluate bone quality in those infected with HIV. OBJECTIVE: To evaluate portable quantitative ultrasonometry (QUS) as an alternative technique to provide information about bone density, bone strength, and the bone turnover markers in HIV-infected people...
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Pablo Carnero-Martín de Soto, Iskandar Tamimi-Mariño, David Bautista-Enrique, María J Bravo-Zurita, Abel Gómez Cáceres, Faleh Tamimi, Marc S Dawid-Milner
OBJECTIVES: To analyze the effect of beta-blockers on the risk of aseptic loosening (AL) in Total Hip (THA) or Knee (TKA) Arthroplasty. METHODS: A nested case-control study was conducted. Cases were patients who underwent revision surgery for THA or TKA due to AL. Controls were patients who sustained primary THA or TKA and were matched to cases in respect to age, sex, type of prostheses and follow-up in a 4:1 ratio. The use of beta-blockers was achieved. A logistic regression analysis adjusted to potential confounders was performed to determine the risk of AL...
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Maddison R Johnstone, Rhys D Brady, Johannes A Schuijers, Jarrod E Church, David Orr, Julian M W Quinn, Stuart J McDonald, Brian L Grills
OBJECTIVES: To study effects of the selective TrkA agonist, gambogic amide (GA), on fracture healing in mice and on an osteoprogenitor cell line in vitro. METHODS: Mice were given bilateral fibular fractures and treated for two weeks with vehicle or 1 mg/kg/day GA and euthanized at 14-, 21-, and 42-days post-fracture. Calluses were analysed by micro-computed tomography (µCT), three-point bending and histology. For RT-PCR analyses, Kusa O cells were treated with 0...
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Steven D Bain, Philippe Huber, Brandon J Ausk, Ronald Y Kwon, Edith M Gardiner, Sundar Srinivasan, Ted S Gross
OBJECTIVES: To clarify the effects of neuromuscular dysfunction on hindlimb loading, muscle atrophy, and bone homeostasis. METHODS: We quantified changes to hindlimb loading, muscle atrophy, and bone morphology following either Botulinum toxin A (BTxA) induced muscle paralysis or peripheral nerve injury (PNI) in mice; two in vivo models that we anticipated would differently alter gait and mechanical loading patterns due to their distinct effects on neuromuscular signaling...
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Camila Santana de Sousa, Fabio Luciano Arcanjo de Jesus, Mariana Barcelos Machado, Grimaldo Ferreira, Isabela Guimarães Tinoco Ayres, Letícia Moraes de Aquino, Thiago Yukio Fukuda, Mansueto Gomes-Neto
OBJECTIVE: To systematically review the published studies that compare lower limb muscle strength in patients with low back pain to matched healthy controls. METHODS: We searched Medline, SciELO, Cumulative Index to Nursing and Allied Health (CINAHL), and Scopus up until December 2017. Studies comparing lower limb muscle strength in people diagnosed with low back pain to healthy control participants were included in the systematic review. RESULTS: 14 studies, which included 951 healthy controls and 919 patients with low back pain, fulfilled the inclusion criteria...
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Ali A Thabet, Mansour A Alshehri
OBJECTIVES: This study was aimed at discovering the efficacy the deep core stability exercise program has on the closure of diastasis recti and on the overall improvement in the quality of life for postpartum women. METHODS: The study group consisted of forty women with diastasis recti, aged between 23 and 33 who were randomly divided into two groups. The 20 women in the first group underwent a deep core stability-strengthening program plus traditional abdominal exercises program, 3 times a week, for a total duration of 8 weeks...
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Luiza Herminia Gallo, Elisângela Valevein Rodrigues, Jarbas Melo Filho, Jordana Barbosa da Silva, Michael O Harris-Love, Anna Raquel Silveira Gomes
OBJECTIVES: The aim of this study was to analyze the effects of virtual dance exercise on skeletal muscle architecture and function in community-dwelling older women. METHODS: Forty-two moderately active older women participated in this study and chose to join either the control group (CG; n=20; 70.3 ± 5.6 years) or exercise group (EG; n=22; 69.3 ± 3.7 years). Participants in the CG maintained their lifestyle and those in the EG performed group dance exercise using Dance Central game for Xbox 360® and Kinect for 40 min, 3 times/week, for 12 weeks...
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Damir Zubac, Armin Paravlić, Katja Koren, Urzi Felicita, Boštjan Šimunič
OBJECTIVE: This study investigated the effects of an 8-week plyometric training (PT) session on countermovement jump (CMJ) height, take-off velocity, and Tensiomyography (TMG) derived contractile parameters in seniors. METHODS: Twenty-three senior adults (age 66.7±5.2 years) were randomly divided into two groups: PLYO (n=11) and CTRL (n=12). Tensiomyography was measured in vastus lateralis (VL), biceps femoris (BF), tibialis anterior (TA), gastrocnemius medialis (GM), and lateralis (GL)...
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Francesco Budini, Daniela Kemper, Monica Christova, Eugen Gallasch, Dietmar Rafolt, Markus Tilp
OBJECTIVES: Corticospinal tract excitability and spinal reflex pathways are transiently affected by short applications of static stretching. However, it remains unclear whether the duration and magnitude of these neurophysiological responses can be increased with a longer duration of the applied stretch. The purpose of this study was to investigate alterations in cortical and spinal excitability following five minutes static stretching. METHODS: Seventeen participants (22...
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Yannis Dionyssiotis, Grigorios Skarantavos, Konstantina Petropoulou, Antonios Galanos, Christina-Anastassia Rapidi, George P Lyritis
OBJECTIVE: Little is known about how appropriate the working definitions of sarcopenia are in subjects with spinal cord injury (SCI). This study aimed to evaluate the application of current sarcopenia definitions in SCI. METHODS: We compared 31 complete SCI men with 33 able-bodied age matched subjects. All were examined by whole body DXA (Norland XR 36, USA) regarding muscle and fat mass and by peripheral quantitative computed tomography (pQCT XCT-3000, Germany) in 66% of tibia's length (muscle cross sectional area, (CSA) in mm2 )...
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Alejandra Mejia Jaramillo, Carl-Éric Aubin, Bahe Hachem, Irene Londono, Juliette Pelletier, Stefan Parent, Isabelle Villemure
OBJECTIVE: To characterize growth plate histology of porcine spines instrumented with a new intra-vertebral staple. METHODS: Spinal segments (T7-T9) previously instrumented with an intra-vertebral staple (experimental group, n=7) or non-instrumented (control group, n=4) underwent average growth rate (AGR), and histomorphometric measurements: heights of proliferative (PZH) and hypertrophic (HZH) growth plate zones, hypertrophic cells height (CH), and the number of proliferative chondrocytes per column (CC)...
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Mireille Larouche Guilbert, Maxime Raison, Carole Fortin, Sofiane Achiche
INTRODUCTION: Gait analysis has often been recognized as helpful for the therapeutic follow-up of adolescents with idiopathic scoliosis (IS). METHODS: A multibody model of the human body was developed to display the intervertebral efforts along the spine of each adolescent with IS, and highlight the efforts that significantly differ from typical age-matched healthy adolescents. The intervertebral efforts of one adolescent with IS and an age-matched adolescent during a complete gait cycle were computed and compared...
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
Augusto Fusco
No abstract text is available yet for this article.
March 1, 2019: Journal of Musculoskeletal & Neuronal Interactions
He Liang, Xinjian Yang, Chao Liu, Zhongyi Sun, Xiaobin Wang
OBJECTIVE: Τo investigate the effect of NF-kB signaling pathway on the expression of MIF, TNF-α, and IL-6 in the regulation of disc degeneration. METHODS: The disc tissue was taken from 56 patients with cervical spondylosis. According to the preoperative MRI and intraoperative disc herniation, the patients were divided into two groups: degeneration group and herniation group. The control group was 34 patients with cervical trauma with no history of cervical spondylosis...
December 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Mohamed A Eid, Sobhy M Aly, Rasha A Mohamed
OBJECTIVES: To evaluate the effectiveness of twister wrap orthosis (TWO) on foot pressure distribution and postural balance in children with spastic diplegic cerebral palsy (CP). METHODS: Thirty children with spastic diplegic CP, with ages ranging from 6 to 8 years, were assigned randomly into two groups. The control group received the conventional physical therapy and ankle foot orthosis (AFO), whereas the study group received the same program as the control group in addition to TWO...
December 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Sophia Stasi, George Papathanasiou, Efstathios Chronopoulos, Antonios Galanos, Nikolaos A Papaioannou, Ioannis K Triantafyllopoulos
OBJECTIVES: To explore associations between abductor strength and functionality in hip-fracture patients. METHODS: Ninety-six participants (70-84 years) followed a 12-week physiotherapy programme emphasizing hip abductor strengthening. The abductor's isometric strength, the hip strength asymmetry (HSA), expressing the ratio of abductor strength in the fractured versus the contralateral hip, and the patients' functional level were recorded 3 months post-intervention...
December 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Junbo Ge, Dongning Sun, Lili Teng, Baifang Su, Xinqing Niu, Wenming Luo
OBJECTIVE: This study aims to explore the effects of 25-hydroxyvitamin D on the bone microstructure of rats with type 2 diabetes mellitus (T2MD). METHODS: 40 male Wistar rats were randomly selected for T2MD modeling and injected with streptozotocin solution. The rats in the control group (n=19) were fed with common feed. 25-hydroxyvitamin D was injected into rats with successful modeling results (Treatment group, n=15). The remaining rats were considered as the model group (n=16)...
December 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
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