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Journals Biochemistry and Molecular Bio...

Biochemistry and Molecular Biology Education

https://read.qxmd.com/read/38516799/use-of-interactive-mathematical-simulations-in-fundamentals-of-biochemistry-a-libretext-online-educational-resource-to-promote-understanding-of-dynamic-reactions
#1
JOURNAL ARTICLE
Henry V Jakubowski, Henry Agnew, Bartholomew Jardine, Herbert M Sauro
Biology is perhaps the most complex of the sciences, given the incredible variety of chemical species that are interconnected in spatial and temporal pathways that are daunting to understand. Their interconnections lead to emergent properties such as memory, consciousness, and recognition of self and non-self. To understand how these interconnected reactions lead to cellular life characterized by activation, inhibition, regulation, homeostasis, and adaptation, computational analyses and simulations are essential, a fact recognized by the biological communities...
March 22, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38501696/exploring-in-the-classroom-the-relationship-between-alcohol-intake-and-behavioral-disorders-through-an-animal-model
#2
JOURNAL ARTICLE
Samanta Hernández-García, M Alejandra Guerrero-Rubio, Paula Henarejos-Escudero, Pedro Martínez-Rodríguez, Fernando Gandía-Herrero
Alcohol consumption has profound effects on behavior, such as impaired judgment, addiction or even death. It is estimated that alcohol contributes to around three million deaths worldwide, 13.5% of them in young people with ages between 20 and 39 years. Consequently, it is necessary to raise awareness among college and high school students of the risk related to alcohol drinking. The small nematode Caenorhabditis elegans is an animal widely used as a model organism to study nearly all aspects of Biochemistry...
March 19, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38456572/the-quantum-mechanics-of-skincare-a-context-for-the-biochemistry-curriculum
#3
JOURNAL ARTICLE
Peter A C McPherson, Lynsey Alphonso, Ben M Johnston
Designing a relevant and engaging curriculum for biochemistry undergraduates can be challenging for topics which are at the periphery of the subject. We have used the framework of context-based learning as a means of assessing understanding of quantum theory in a group of students in their junior year. Our context, the role of retinol in skincare, provides a basis for the simple application of quantum mechanical principles to a biological context in an adaptation of the polyene in a box concept. As part of the learner journey, they gain experience of practical computational chemistry, which provided an in silico alternative to traditional laboratory work during the SARS-CoV-19 pandemic...
March 8, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38415967/development-of-an-integrated-and-project-based-laboratory-course-in-upper-level-biochemistry-and-molecular-biology
#4
JOURNAL ARTICLE
Yange Liu, Shuo Tu, Xiaojuan Hu, Xiangyang Xiong, Zezheng Pan, Zhuoqi Liu, Weifeng Zhu, Daya Luo, Xiangpei Cui, Chunhong Huang, Caifeng Xie
An integrated and projected-based laboratory course was described, integrating interconnected knowledge points and biochemistry and molecular biology techniques on a research project-based system. The program, which served as an essential extension of theoretical courses to practice, was conducted with a sophomore of basic medical science who had completed the course in medical biochemistry and molecular biology. This course engaged students in learning "genetic manipulation" and "recombinant DNA technology" to understand the target gene's role in disease mechanics, thus altering evaluation and treatment for clinical disease...
February 28, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38411374/if-you-are-learner-centered-and-you-know-it-raise-your-hand-perspectives-on-and-implementation-of-pedagogical-changes-by-science-instructors-during-the-covid-19-pandemic
#5
JOURNAL ARTICLE
Cristine Donham, Hanbo Hong, Adriana Signorini, Erik Menke, Petra Kranzfelder
Students at Minority-Serving Institutions (MSIs) faced significant hardships while trying to learn through emergency remote teaching (ERT) during the COVID-19 pandemic. Our research aims to investigate if science, technology, engineering, and mathematics (STEM) instructors thought about and enacted more learner-centered teaching practices to alleviate some of this stress encountered by their students. Using semi-structured interviews and classroom observations, we utilized inductive and deductive qualitative research methods to examine two questions: (1) To what extent were STEM instructor's perceived pedagogical changes learner-centered during ERT?; and (2) To what extent were STEM instructor's teaching behaviors and discourse practices learner-centered during ERT? Our findings revealed that during ERT, STEM instructors described using a variety of pedagogical changes that we identified as learner-centered under the Weimer framework, including ideas such as enacting flexible late policies and increased usage of formative assessment...
February 27, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38411364/use-of-onenote-class-notebook-as-a-combined-electronic-laboratory-notebook-and-content-delivery-tool-in-an-introductory-biochemistry-laboratory-course
#6
JOURNAL ARTICLE
Ahlia Khan-Trottier
The COVID-19 pandemic has forced a shift in thinking regarding the safe delivery of wet laboratory courses. While we were fortunate to have the capacity to continue delivering wet laboratory experiments with physical distancing and other measures in place, modifications to the mechanisms of delivery within courses were necessary to minimize risk to students and teaching staff. One such modification was introduced in BCH370H, an introductory biochemistry laboratory course, where a OneNote Class Notebook (ONCN) was used as an electronic laboratory notebook (ELN) in place of the traditional hardbound paper laboratory notebook (PLN) used prior to the pandemic...
February 27, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38409737/an-idea-to-explore-cultivating-the-art-of-proposal-writing-among-graduate-students
#7
JOURNAL ARTICLE
Rajiv K Kar
Proposal writing is an essential requirement for making progress in academics. Learning this skill necessitates support from a mentor to cultivate effective habits. It entails effective strategies from graduate students, such as literature reading and using online tools. Additionally, they must develop an understanding of resource accountability, system thinking, and considering deadlines as a driving force. Good practices for effective proposal writing also involve planning to summarize the work done in the field...
February 26, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38400827/enzyme-kinetics-analysis-an-online-tool-for-analyzing-enzyme-initial-rate-data-and-teaching-enzyme-kinetics
#8
JOURNAL ARTICLE
Daniel A Mak, Sebastian Dunn, David Coombes, Carlo R Carere, Jane R Allison, Volker Nock, André O Hudson, Renwick C J Dobson
Enzymes are nature's catalysts, mediating chemical processes in living systems. The study of enzyme function and mechanism includes defining the maximum catalytic rate and affinity for substrate/s (among other factors), referred to as enzyme kinetics. Enzyme kinetics is a staple of biochemistry curricula and other disciplines, from molecular and cellular biology to pharmacology. However, because enzyme kinetics involves concepts rarely employed in other areas of biology, it can be challenging for students and researchers...
February 24, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38400823/detection-and-enzymatic-characterization-of-human-saliva-amylase
#9
JOURNAL ARTICLE
Chiara Theresa Vey, Viola Kaygusuz, Josefa Sophia Kayser, Andreas Beyer
As a rule, an experiment carried out at school or in undergraduate study courses is rather simple and not very informative. However, when the experiments are to be performed using modern methods, they are often abstract and difficult to understand. Here, we describe a quick and simple experiment, namely the enzymatic characterization of ptyalin (human salivary amylase) using a starch degradation assay. With the experimental setup presented here, enzyme parameters, such as pH optimum, temperature optimum, chloride dependence, and sensitivity to certain chemicals can be easily determined...
February 24, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38358340/an-early-curricular-team-learning-activity-to-foster-integration-of-biochemical-concepts-and-clinical-sciences-in-undergraduate-medical-education
#10
JOURNAL ARTICLE
Martin Schmidt, Brian Pinney, Craig Canby, April Vargus, Marianka Pille
The ability to connect key concepts of biochemistry with clinical presentations is essential for the development of clinical reasoning skills and adaptive expertise in medical trainees. To support the integration of foundational and clinical sciences in our undergraduate health science curricula, we developed a small group active learning exercise during which interprofessional groups of students use clinical cases to explore the biochemistry, diagnostic strategy, and evidence-based treatment options of inborn errors of metabolism (IEM)...
February 15, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38348907/methods-of-biotechnology-biotech-biobrawl-a-competition-based-learning-approach-to-biotechnology
#11
JOURNAL ARTICLE
Nicholas Skiados, Rabeea Summer Rehman, Megan Riley, Kersten T Schroeder
Biotechnology students entering the workforce often struggle in their application of textbook knowledge to build the solutions that we see in science and health fields today. Some students may be naive to what a job in the biotechnology industry can encompass. Students should graduate having a firm grasp of the prospects of their field and have the confidence to begin contributing to the growth of the industry. For this, it is necessary for students to be able to start practising applications in their coursework before they graduate...
February 13, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38319132/an-idea-to-explore-introduction-of-biochemical-tales-in-medical-education-learning-made-fun
#12
JOURNAL ARTICLE
Krishna Mohan Surapaneni
Innovations in medical education, including the integration of narrative-based tales, are transforming the way complex biochemical concepts are taught and understood. In this "Idea to Explore", the essence of integrating tales that personify molecules and depict biochemical processes as engaging stories to enhance student engagement, promote active learning, and improve knowledge retention is discussed. It also explores the effectiveness of scientific discovery games and traditional scientific stories in deepening students' interest in biochemistry...
February 6, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38308542/the-implementation-of-an-active-inquiry-learning-centered-7e-teaching-mode-in-the-cell-biology-course-enhances-the-learning-effects-of-postgraduate-students
#13
JOURNAL ARTICLE
Jingjing Han, Lina Zhang, Liucai Yang, Yougen Luo, Ruiqin Yao, Xuebin Qu
The primary objective of science postgraduate education is to foster students' capacity for creative thinking and problem-solving, particularly in the context of scientific research quality. In order to achieve this goal, the "7E" teaching mood has been implemented in the cell biology course for postgraduate students to promote student-centered active inquiry learning instead of breaking away from traditional indoctrination-based teaching methods. This study demonstrates that the implementation of the "7E" teaching mode, through content programming, process design, and effect evaluation, effectively meets the needs of the majority of students, fosters their interest in learning, enhances their performance in comprehensive questioning, and enhances their innovative abilities in scientific research...
February 3, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38308532/an-interdisciplinary-course-on-computer-aided-drug-discovery-to-broaden-student-participation-in-original-scientific-research
#14
JOURNAL ARTICLE
Christopher Stratton, Avery Christensen, Chelsey Jordan, Brian A Salvatore, Elahe Mahdavian
We present a new highly interdisciplinary course in computer-aided drug discovery (CADD). This course was developed in response to a call for alternative pedagogical approaches during the COVID-19 pandemic, which caused the cancellation of a face-to-face summer research program sponsored by the Louisiana Louisiana Biomedical Research Network (LBRN). The course integrates guided research and educational experiences for chemistry, biology, and computer science students. We implement research-based methods with publicly available tools in bioinformatics and molecular modeling to identify and prioritize promising anti-viral drug candidates...
February 3, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38308530/assessment-of-the-effectiveness-of-an-introductory-general-chemistry-course-in-dentistry-students-enrolled-in-a-biochemistry-course
#15
JOURNAL ARTICLE
Gloria Gutiérrez-Venegas, Marisol Rosas-Martínez, Itzel Juárez-Ramos, Jesús Iván Jiménez-Rivera
As a strategy to carry out a better achievement in the Biochemistry course, undergraduate dentistry education manage a traditional course on the basic concepts of general chemistry necessary in the understanding of Biochemistry. In order to evaluate the effectiveness of learning outcome, we aimed to develop an evaluation tool that was applied to first-year dental students before and after receiving the general chemistry classes. Randomized trial consisted of 50 items distributed in 10 categories. The evaluation was applied to the students who took the Oral Biology course in the periods comprising 2020, 2021, and 2022 to a population of 109 students...
February 3, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38270246/biomedical-students-satisfaction-with-and-engagement-in-laboratory-e-learning-support-are-related-to-their-self-regulation
#16
JOURNAL ARTICLE
C B Moelans, J J Geerling, R D Radersma, M J Moons, P J van Diest, M F van der Schaaf
Laboratory e-learning support tools can assist students' learning while preparing for laboratory classes. To successfully work in such virtual experimental environments (VEEs) outside class, students require self-regulated learning (SRL) skills. A deeper understanding of the continuous reciprocal interactions between SRL, satisfaction, and online engagement is needed to develop more effective online learning experiences. This study therefore aimed to explore the interconnection between students' satisfaction with, effort/importance and engagement in an exemplary VEE, and to relate this to their perceived SRL and learning outcomes...
January 25, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38226712/blended-learning-in-biochemistry-the-development-of-pre-class-and-post-class-learning-aids-for-electron-transport-chain-and-oxidative-phosphorylation
#17
JOURNAL ARTICLE
Rebecca K Y Lee, Bernard Y N Ng, Daisy M H Chen
Electron transport chain and oxidative phosphorylation are always a challenging topic for students studying metabolism. We had adopted blended learning in metabolism teaching and evaluated the learning experiences of students. In this project, a pre-class learning aid the Story Mode and a post-class learning aid the Revision Mode in the Powerland was developed that facilitated students learning electron transport chain and oxidative phosphorylation. In the Story Mode, pathways were presented by short animations and simplified diagram that allowed students to understand basic concepts and recall simple facts of the topic...
January 16, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38217460/assessment-of-early-scientific-research-skills-training-for-medical-undergraduates-in-china
#18
JOURNAL ARTICLE
Xueer Liu, Huiyu Chen, Xiaoying Liu, Teng Teng, Xuemei Li, Dan Zhu, Xinyu Zhou
The medical field is facing a physician-scientist shortage, threatening future medical research and development. Medical institutions can contribute to developing physician-scientists by stimulating students' involvement in research. In this study, a medical undergraduate teaching module to develop research skills and encourage interest in research was held in Chongqing, China. Undergraduate medical students at Chongqing Medical University completed research skills training. Before and after the training, an online, anonymous, self-reported questionnaire was administered...
January 13, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38217452/multi-focused-laboratory-experiments-based-on-quorum-sensing-and-quorum-quenching-for-acquiring-microbial-physiology-concepts
#19
JOURNAL ARTICLE
Mariela Analía Torres, Alejandra Leonor Valdez, Carolina de Lourdes Olea, María Fernanda Figueroa, Carlos Gabriel Nieto-Peñalver
After a time away from the classrooms and laboratories due to the global pandemic, the return to teaching activities during the semester represented a challenge to both teachers and students. Our particular situation in a Microbial Physiology course was the necessity of imparting in shorter time, laboratory practices that usually take longer. This article describes a 2-week-long laboratory exercise that covers several concepts in an interrelated way: conjugation as a gene transfer mechanism, regulation of microbial physiology, production of secondary metabolites, degradation of macromolecules, and biofilm formation...
January 13, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38197506/teaching-biologics-design-using-molecular-modeling-and-simulations
#20
JOURNAL ARTICLE
Andrew Phillips, Anusha Srinivas, Ilina Prentoska, Margaret O'Dea, Matthew Kustrup, Sarah Hurley, Savannah Bruno, Vy Nguyen, Pin-Kuang Lai
Teaching chemistry and biology students about biologics design remains challenging despite its increasing importance in pharmaceutical development. Monoclonal antibodies, commonly called mAbs, are the most popular biologics. They have been developed into drugs to treat various diseases in the past decades. Multiple challenges exist for designing proper formulations to stabilize mAbs, such as preventing aggregation and mitigating viscosity. Molecular modeling and simulations can improve pharmaceutical products by examining the interactions between mAbs and other compounds, such as excipients...
January 10, 2024: Biochemistry and Molecular Biology Education
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