Shu-Hua Huang, Wen-Chiu Hsiao, Hsin-I Chang, Mi-Chia Ma, Shih-Wei Hsu, Chen-Chang Lee, Hong-Jie Chen, Ching-Heng Lin, Chi-Wei Huang, Chiung-Chih Chang
BACKGROUND: Based on a longitudinal cohort design, the aim of this study was to investigate whether individual-based 18 F fluorodeoxyglucose positron emission tomography (18 F-FDG-PET) regional signals can predict dementia conversion in patients with mild cognitive impairment (MCI). METHODS: We included 44 MCI converters (MCI-C), 38 non-converters (MCI-NC), 42 patients with Alzheimer's disease with dementia, and 40 cognitively normal controls. Data from annual cognitive measurements, 3D T1 magnetic resonance imaging (MRI) scans, and 18 F-FDG-PET scans were used for outcome analysis...
March 28, 2024: BMC Medical Imaging