journal
https://read.qxmd.com/read/38644489/comparison-of-outcomes-and-characteristics-of-patients-admitted-to-the-icu-with-covid-19-and-other-community-acquired-pneumonia-based-on-propensity-score-matching
#1
JOURNAL ARTICLE
Hongli Zhao, Xiulin Yan, Ziru Guo, Kaiyu Li, Zhaopeng Wang, Jun Wang, Dong Lv, Jianling Zhu, Ye Chen
OBJECTIVE: To compare the similarities and differences between patients with Coronavirus Disease 2019 (COVID-19) and those with other community-acquired pneumonia (CAP) admitted to the intensive care unit (ICU), utilizing propensity score matching (PSM), regarding hospitalization expenses, treatment options, and prognostic outcomes, aiming to inform the diagnosis and treatment of COVID-19. METHODS: Patients admitted to the ICU of the Third People's Hospital of Datong City, diagnosed with COVID-19 from December 2022 to February 2023, constituted the observation group, while those with other CAP admitted from January to November 2022 formed the control group...
April 22, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38644476/exploring-variations-in-ipc-competencies-a-cross-sectional-study-among-healthcare-professionals-in-northwest-china
#2
JOURNAL ARTICLE
Qinglan Zhao, Xiaoqing Cui, Ting Liu, Hanxue Li, Miaoyue Shi, Li Wang
BACKGROUND: This cross-sectional study investigates infection prevention and control (IPC) competencies among healthcare professionals in northwest China, examining the influence of demographic factors, job titles, education, work experience, and hospital levels. METHODS: Data from 874 respondents across 47 hospitals were collected through surveys assessing 16 major IPC domains. Statistical analyses, including Mann-Whitney tests, were employed to compare competencies across variables...
April 22, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38644471/predictors-of-mortality-and-poor-outcome-for-patients-with-severe-infectious-encephalitis-in-the-intensive-care-unit-a-cross-sectional-study
#3
JOURNAL ARTICLE
WenYan Zhao, YuLiang Zhou, YingYing Hu, WenJing Luo, Jing Wang, Hong Zhu, ZhiPeng Xu
BACKGROUND: There are few thorough studies assessing predictors of severe encephalitis, despite the poor prognosis and high mortality associated with severe encephalitis. The study aims to evaluate the clinical predictors of mortality and poor outcomes at hospital discharge in patients with severe infectious encephalitis in intensive care units. METHOD: In two Chinese hospitals, a retrospective cohort study comprising 209 patients in intensive care units suffering from severe infectious encephalitis was carried out...
April 22, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38641804/early-predictors-of-delayed-radiographic-resolution-of-lobar-pneumonia-caused-by-mycoplasma-pneumoniae-in-children-a-retrospective-study-in-china
#4
JOURNAL ARTICLE
Yu Zheng, Guoshun Mao, Hongchen Dai, Guitao Li, Liying Liu, Xiaying Chen, Ying Zhu
BACKGROUND: Lobar pneumonia caused by Mycoplasma pneumoniae is a relatively difficult-to-treat pneumonia in children. The time of radiographic resolution after treatment is variable, a long recovery time can result in several negative effects, and it has attracted our attention. Therefore, exploring factors associated with delayed radiographic resolution will help to identify these children at an early stage and prepare for early intervention. METHODS: The data of 339 children with lobar pneumonia caused by Mycoplasma pneumoniae were collected from the Department of Pediatrics of Fu Yang People's Hospital, China from January 2021 to June 2022...
April 19, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38641791/immunogenicity-and-safety-of-a-recombinant-covid-19-vaccine-zf2001-as-heterologous-booster-after-priming-with-inactivated-vaccine-in-healthy-children-and-adolescents-aged-3-17-years-an-open-labeled-single-arm-clinical-trial
#5
JOURNAL ARTICLE
Tao Huang, Qianqian Hu, Xiang Zhou, Huaiyu Yang, Wei Xia, Feng Cao, Minglu Deng, Xiaoxue Teng, Fan Ding, Zaixin Zhong, Lidong Gao, Jiufeng Sun, Lihui Gong
Considering that neutralizing antibody levels induced by two doses of the inactivated vaccine decreased over time and had fallen to low levels by 6 months, and homologous and heterologous booster immunization programs have been implemented in adults in China. The booster immunization of recombinant COVID-19 vaccine (ZF2001) after priming with inactivated vaccine in healthy children and adolescents has not been reported. We performed an open-labeled, single-arm clinical trial to evaluate the safety and immunogenicity of heterologous booster immunization with ZF2001 after priming with inactivated vaccine among 240 population aged 3-17 years in China...
April 19, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38641776/prevalence-and-factors-associated-with-hiv-testing-among-young-women-in-ghana
#6
JOURNAL ARTICLE
Mainprice Akuoko Essuman, Hidaya Mohammed, Martha Suntah Kebir, Comfort Obiribea, Bright Opoku Ahinkorah
BACKGROUND: HIV/AIDS is a global health challenge and continues to threaten lives in sub-Saharan African countries such as Ghana. One of the important interventions for controlling its transmission is through testing and receiving medication. In this study, we present findings on the prevalence and factors associated with HIV testing among young women in Ghana. METHODS: We used data from the 2014 Ghana Demographic and Health Survey comprising young women aged 15-24 years...
April 19, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38641597/comparison-of-safety-and-effectiveness-of-antiretroviral-therapy-regimens-among-pregnant-women-living%C3%A2-with-hiv-at-preconception-or-during-pregnancy-a-systematic-review-and-network-meta-analysis-of-randomized-trials
#7
Fatemeh Mehrabi, Mohammad Karamouzian, Behnam Farhoudi, Shahryar Moradi Falah Langeroodi, Soheil Mehmandoost, Samaneh Abbaszadeh, Shahrzad Motaghi, Ali Mirzazadeh, Behnam Sadeghirad, Hamid Sharifi
BACKGROUND: Mother-to-child transmission is the primary cause of HIV cases among children. Antiretroviral therapy (ART) plays a critical role in preventing mother-to-child transmission and reducing HIV progression, morbidity, and mortality among mothers. However, after more than two decades of ART during pregnancy, the comparative effectiveness and safety of ART medications during pregnancy are unclear, and existing evidence is contradictory. This study aimed to assess the effectiveness and safety of different ART regimens among pregnant women living with HIV at preconception or during pregnancy...
April 19, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38641583/virulence-antibiotic-resistance-phenotypes-and-molecular-characterisation-of-vibrio-furnissii-isolates-from-patients-with-diarrhoea
#8
JOURNAL ARTICLE
Yanyan Zhou, Li Yu, Ming Liu, Weili Liang, Zhenpeng Li, Zheng Nan, Biao Kan
BACKGROUND: Vibrio furnissii is an emerging human pathogen closely related to V. fluvialis that causes acute gastroenteritis. V. furnissii infection has been reported to be rarer than V. fluvialis, but a multi-drug resistance plasmid has recently been discovered in V. furnissii. METHODS: During daily monitoring at a general hospital in Beijing, China, seven V. furnissii strains were collected from patients aged over 14 years who presented with acute diarrhoea between April and October 2018...
April 19, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38641577/cost-utility-analysis-of-palivizumab-for-preventing-respiratory-syncytial-virus-in-preterm-neonates-and-infants-in-colombia
#9
JOURNAL ARTICLE
Jaime E Ordóñez, Victor M Huertas
AIM: Palivizumab has proven effective in reducing hospitalizations, preventing severe illness, improving health outcomes, and reducing healthcare costs for infants at risk of respiratory syncytial virus (RSV) infection. We aim to assess the value of palivizumab in preventing RSV infection in high-risk infants in Colombia, where RSV poses a significant threat, causing severe respiratory illness and hospitalizations. METHODS: We conducted a decision tree analysis to compare five doses of palivizumab with no palivizumab...
April 19, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38641565/key-informant-views-on-potential-acceptability-and-feasibility-of-long-acting-antiretroviral-treatment-for-hiv-in-kenya
#10
JOURNAL ARTICLE
Anne Kaggiah, Catherine N Maina, John Kinuthia, Douglas Barthold, Brett Hauber, Jacinda Tran, Jane M Simoni, Susan M Graham
BACKGROUND: In 2020, 14% of diagnosed persons living with HIV (PLWH) in Kenya were not taking antiretroviral therapy (ART), and 19% of those on ART had unsuppressed viral loads. Long-acting antiretroviral therapy (LA-ART) may increase viral suppression by promoting ART uptake and adherence. We conducted key informant (KI) interviews with HIV experts in Kenya to identify product and delivery attributes related to the acceptability and feasibility of providing LA-ART to PLWH in Kenya. METHODS: Interviews were conducted via Zoom on potential LA-ART options including intra-muscular (IM) injections, subcutaneous (SC) injections, implants, and LA oral pills...
April 19, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38637727/the-predictive-power-of-data-machine-learning-analysis-for-covid-19-mortality-based-on-personal-clinical-preclinical-and-laboratory-variables-in-a-case-control-study
#11
JOURNAL ARTICLE
Maryam Seyedtabib, Roya Najafi-Vosough, Naser Kamyari
BACKGROUND AND PURPOSE: The COVID-19 pandemic has presented unprecedented public health challenges worldwide. Understanding the factors contributing to COVID-19 mortality is critical for effective management and intervention strategies. This study aims to unlock the predictive power of data collected from personal, clinical, preclinical, and laboratory variables through machine learning (ML) analyses. METHODS: A retrospective study was conducted in 2022 in a large hospital in Abadan, Iran...
April 18, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38632544/seromolecular-study-on-the-prevalence-and-risk-factors-of-toxoplasma-gondii-infection-in-pregnant-women-referred-to-a-gynecology-hospital-in-urmia-northwest-part-of-iran-in-2022
#12
JOURNAL ARTICLE
Nasim Bashour, Arash Aminpour, Shabnam Vazifehkhah, Rasool Jafari
Toxoplasmosis is a frequent infection among the human population. The infection can cause devastating complications for the fetus during pregnancy. The present study aimed to determine the serological and molecular prevalence of the infection and molecular characterization of Toxoplasma gondii isolates among pregnant women referred to Kowsar Hospital, Urmia, Iran. In a cross-sectional study, 340 blood samples were collected from pregnant women referred to Kowsar Hospital, Urmia, Iran from May to July 2022. Anti-T...
April 17, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38632536/utility-of-paired-plasma-and-drainage-fluid-mngs-in-diagnosing-acute-intra-abdominal-infections-with-sepsis
#13
JOURNAL ARTICLE
Jia-Yu Mao, Dong-Kai Li, Dong Zhang, Qi-Wen Yang, Yun Long, Na Cui
BACKGROUND: Metagenomic next-generation sequencing (mNGS) has been increasingly applied in sepsis. We aimed to evaluate the diagnostic and therapeutic utility of mNGS of paired plasma and peritoneal drainage (PD) fluid samples in comparison to culture-based microbiological tests (CMTs) among critically ill patients with suspected acute intra-abdominal infections (IAIs). METHODS: We conducted a prospective study from October 2021 to December 2022 enrolling septic patients with suspected IAIs (n = 111)...
April 17, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38627642/implementation-of-a-rapid-diagnostic-assay-package-for-cryptococcosis-histoplasmosis-and-tuberculosis-in-people-living-with-hiv-in-paraguay
#14
JOURNAL ARTICLE
Gloria Aguilar, Gladys Lopez, Omar Sued, Narda Medina, Diego H Caceres, Jose Pereira, Alexander Jordan, Virgilio Lezcano, Cristina Vicenti, Gustavo Benitez, Tania Samudio, Freddy Perez
BACKGROUND: Opportunistic infections (OIs) are common causes of mortality among people living with HIV (PLHIV). We determined prevalence and 30-day mortality due to histoplasmosis, cryptococcosis, and TB in PLHIV with advanced HIV disease (AHD). METHODS: PLHIV 18 years and older, with a CD4 + T-cell count of less than 350 cells/mm3 newly diagnosed with HIV infection or re-engaged in care after being without ART for more than 90 days (Group A). The second group included symptomatic PLHIV regardless of ART status or CD4 + T-cell count (Group B); all followed for 30 days...
April 16, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38627637/modelling-the-impact-of-hybrid-immunity-on-future-covid-19-epidemic-waves
#15
JOURNAL ARTICLE
Thao P Le, Isobel Abell, Eamon Conway, Patricia T Campbell, Alexandra B Hogan, Michael J Lydeamore, Jodie McVernon, Ivo Mueller, Camelia R Walker, Christopher M Baker
BACKGROUND: Since the emergence of SARS-CoV-2 (COVID-19), there have been multiple waves of infection and multiple rounds of vaccination rollouts. Both prior infection and vaccination can prevent future infection and reduce severity of outcomes, combining to form hybrid immunity against COVID-19 at the individual and population level. Here, we explore how different combinations of hybrid immunity affect the size and severity of near-future Omicron waves. METHODS: To investigate the role of hybrid immunity, we use an agent-based model of COVID-19 transmission with waning immunity to simulate outbreaks in populations with varied past attack rates and past vaccine coverages, basing the demographics and past histories on the World Health Organization Western Pacific Region...
April 16, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38627630/effect-of-concurrent-infection-of-helicobacter-pylori-with-toxoplasma-gondii-infection-on-gastric-pathology
#16
JOURNAL ARTICLE
Marwa A Gouda, Sara A Saied, Ahmed Edrees, Rasha Galal Mostafa, Ashraf Elfert, Aya Abdallah Seleem, Asmaa Shams, Sameh Afify
BACKGROUND: Toxoplasma gondii (T. gondii) and Helicobacter pylori (H. pylori) are among the most prevalent foodborne parasitic and bacterial infections worldwide. However, the concurrent impact of coinfection on gastric pathology has yet to be studied in depth. The effect of coinfection generally either adds a synergetic or antagonistic impact; we aimed in the current work to assess the impact of T. gondii coinfection on the progression of H. pylori-associated gastric pathology and reporting H...
April 16, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38622570/a-systematic-review-and-meta-analysis-of-circulating-serum-and-plasma-micrornas-in-tb-diagnosis
#17
JOURNAL ARTICLE
Harinisri Gunasekaran, Pavithra Sampath, Kannan Thiruvengadam, Muniyandi Malaisamy, Rathinasabapati Ramasamy, Uma Devi Ranganathan, Ramalingam Bethunaickan
BACKGROUND: Tuberculosis (TB) ranks as the second leading cause of death globally among all infectious diseases. This problem is likely due to the lack of biomarkers to differentiate the heterogeneous spectrum of infection. Therefore, the first step in solving this problem is to identify biomarkers to distinguish the different disease states of an individual and treat them accordingly. Circulating microRNA (miRNA) biomarkers are promising candidates for various diseases. In fact, we are yet to conceptualize how miRNA expression influences and predicts TB disease outcomes...
April 15, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38622539/the-global-patent-landscape-of-emerging-infectious-disease-monkeypox
#18
JOURNAL ARTICLE
Yuanqi Cai, Xiaoming Zhang, Kuixing Zhang, Jingbo Liang, Pingping Wang, Jinyu Cong, Xin Xu, Mengyao Li, Kunmeng Liu, Benzheng Wei
BACKGROUND: Monkeypox is an emerging infectious disease with confirmed cases and deaths in several parts of the world. In light of this crisis, this study aims to analyze the global knowledge pattern of monkeypox-related patents and explore current trends and future technical directions in the medical development of monkeypox to inform research and policy. METHODS: A comprehensive study of 1,791 monkeypox-related patents worldwide was conducted using the Derwent patent database by descriptive statistics, social network method and linear regression analysis...
April 15, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38622527/increased-tuberculosis-case-detection-in-tanzanian-children-and-adults-using-african-giant-pouched-rats
#19
JOURNAL ARTICLE
Tefera B Agizew, Joseph Soka, Cynthia D Fast, Stephen Mwimanzi, Gilbert Mwesiga, Nashon Edward, Marygiven Stephen, Reheme Kondo, Robert Burny, Christophe Cox, Negussie Beyene
BACKGROUND: African giant pouched rats, trained by Anti-Persoonsmijnen Ontmijnende Product Ontwikkeling (APOPO), have demonstrated their ability to detect tuberculosis (TB) from sputum. We assessed rat-based case detection and compared the mycobacterium bacillary load (MTB-load) in children versus adults. METHODS: From January-December 2022, samples were collected prospectively from 69 Directly Observed Therapy (DOT) facilities' presumed TB patients. Using an average of five rats, APOPO re-evaluated patients with bacteriologically negative (sputum-smear microscopy or Xpert MTB/RIF) results...
April 15, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38622501/characterization-of-genital-chlamydia-trachomatis-infection-among-women-attending-infertility-and-gynecology-clinics-in-hunan-china
#20
JOURNAL ARTICLE
Qianting Zhou, Jiayan Li, Lipei Luo, Shuling Min, Li Wang, Lixiu Peng, Yinglan Hou, Ping He, Song He, Shixing Tang, Hongliang Chen
BACKGROUND: Genital infection with Chlamydia trachomatis (C. trachomatis) is a major public health issue worldwide. It can lead to cervicitis, urethritis, and infertility. This study was conducted to determine the characteristics of genital C. trachomatis infection among women attending to the infertility and gynecology clinics. METHODS: Endocervical swabs were collected from 8,221 women for C. trachomatis nucleotide screening and genotyping, while serum samples were collected for C...
April 15, 2024: BMC Infectious Diseases
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