journal
https://read.qxmd.com/read/38632503/conditional-survival-and-annual-hazard-of-death-in-older-patients-with-esophageal-cancer-receiving-definitive-chemoradiotherapy
#1
JOURNAL ARTICLE
Xiao Chang, Wei Deng, Rong Yu, Weihu Wang
BACKGROUND: Definitive chemoradiotherapy is one of the primary treatment modalities for older patients with esophageal cancer (EC). However, the evolution of prognosis over time and the factors affected non-EC deaths remain inadequately studied. We examined the conditional survival and annual hazard of death in older patients with EC after chemoradiotherapy. METHODS: We collected data from patients aged 65 or older with EC registered in the Surveillance, Epidemiology, and End Results database during 2000-2019...
April 17, 2024: BMC Geriatrics
https://read.qxmd.com/read/38627620/which-comprehensive-geriatric-assessment-cga-instruments-are-currently-used-in-germany-a-survey
#2
JOURNAL ARTICLE
Jennifer Kudelka, Malte Ollenschläger, Richard Dodel, Bjoern M Eskofier, Markus A Hobert, Klaus Jahn, Jochen Klucken, Bendix Labeit, M Cristina Polidori, Tino Prell, Tobias Warnecke, Christine A F von Arnim, Walter Maetzler, Andreas H Jacobs
BACKGROUND: The Comprehensive Geriatric Assessment (CGA) records geriatric syndromes in a standardized manner, allowing individualized treatment tailored to the patient's needs and resources. Its use has shown a beneficial effect on the functional outcome and survival of geriatric patients. A recently published German S1 guideline for level 2 CGA provides recommendations for the use of a broad variety of different assessment instruments for each geriatric syndrome. However, the actual use of assessment instruments in routine geriatric clinical practice and its consistency with the guideline and the current state of literature has not been investigated to date...
April 17, 2024: BMC Geriatrics
https://read.qxmd.com/read/38627748/cluster-analysis-dissecting-cognitive-deficits-in-older-adults-with-major-depressive-disorder-and-the-association-with-neurofilament-light-chain
#3
JOURNAL ARTICLE
Cynthia Yi-An Chen, Chih-Chiang Chiu, Cho-Yin Huang, Ying-Chih Cheng, Ming-Chyi Huang, Po-Hsiu Kuo, Wen-Yin Chen
BACKGROUND: Cognitive impairment is a growing problem with increasing burden in global aging. Older adults with major depressive disorder (MDD) have higher risk of dementia. Neurofilament light chain (NfL) has been proven as a potential biomarker in neurodegenerative disease, including dementia. We aimed to investigate the association between cognitive deficits and NfL levels in older adults with MDD. METHODS: In this cross-sectional study, we enrolled 39 MDD patients and 15 individuals with mild neurocognitive disorder or major neurocognitive disorder, Alzheimer's type, as controls, from a tertiary psychiatric hospital...
April 16, 2024: BMC Geriatrics
https://read.qxmd.com/read/38627654/development-of-a-program-theory-for-osteoporosis-patient-education-in-denmark-a-qualitative-study-based-on-realist-evaluation
#4
JOURNAL ARTICLE
Mette Rubæk, Marie Broholm-Jørgensen, Susan Andersen, Pernille Ravn Jakobsen, Mette Juel Rothmann, Bente Langdahl, Mette Friberg Hitz, Teresa Holmberg
BACKGROUND: Osteoporosis patient education is offered in many countries worldwide. When evaluating complex interventions like these, it is important to understand how and why the intervention leads to effects. This study aimed to develop a program theory of osteoporosis patient education in Danish municipalities with a focus on examining the mechanisms of change i.e. what is about the programs that generate change. METHODS: The program theory was developed in an iterative process...
April 16, 2024: BMC Geriatrics
https://read.qxmd.com/read/38627618/a-qualitative-perspective-of-working-women-care-providers-and-care-receivers-on-eldercare-a-study-from-india
#5
JOURNAL ARTICLE
Dipti Govil, Harihar Sahoo, Biswabandita Chowdhury, K S James
BACKGROUND: The paper aims to explore the elderly caregiving process in India from the perspective of both elderly as well as working women care providers, along with the challenges faced and the coping strategies adopted by them during the process. METHODS: In-depth interviews with 48 participants (care providers and care receivers) from 25 multi-generational households were conducted in the slums of Mumbai and analysed using QSR-NVivo-10. RESULTS: Working women care providers supported the needs of the dependent elderly along with performing household chores and paid work...
April 16, 2024: BMC Geriatrics
https://read.qxmd.com/read/38622574/the-causal-relationship-of-human-blood-metabolites-with-the-components-of-sarcopenia-a-two-sample-mendelian-randomization-analysis
#6
JOURNAL ARTICLE
Wenxi Peng, Zhilin Xia, Yaxuan Guo, Linghong Li, Jianrong He, Yi Su
BACKGROUND: Sarcopenia is a progressive loss of muscle mass and function. Since skeletal muscle plays a critical role in metabolic homeostasis, identifying the relationship of blood metabolites with sarcopenia components would help understand the etiology of sarcopenia. METHODS: A two-sample Mendelian randomization study was conducted to examine the causal relationship of blood metabolites with the components of sarcopenia. Summary genetic association data for 309 known metabolites were obtained from the Twins UK cohort and KORA F4 study (7824 participants)...
April 15, 2024: BMC Geriatrics
https://read.qxmd.com/read/38622572/predictive-value-of-the-systemic-immune-inflammation-index-on-one-year-mortality-in-geriatric-hip-fractures
#7
JOURNAL ARTICLE
Zekeriya Ersin Çelen
BACKGROUND: Geriatric hip fractures are associated with a high incidence of mortality. This study examines the predictive value of the systemic immune-inflammation index (SII) on one-year mortality in elderly hip fracture patients. METHODS: A single-center retrospective study was conducted between February 2017 and October 2020. Three hundred and eleven surgically treated consecutive hip fracture patients were included in the study. Admission, postoperative first day, and postoperative fifth-day SII values were calculated...
April 15, 2024: BMC Geriatrics
https://read.qxmd.com/read/38622550/risk-factors-of-different-mortality-periods-in-older-patients-with-end-stage-renal-disease-undergoing-urgent-start-peritoneal-dialysis-a-retrospective-observational-study
#8
JOURNAL ARTICLE
Shizheng Guo, Liming Yang, Xueyan Zhu, Xiaoxuan Zhang, Zhanshan Sun, Lingfei Meng, Yangwei Wang, Jian Li, Siyu Cheng, Xiaohua Zhuang, Wenpeng Cui
BACKGROUND: The first six months of therapy represents a high-risk period for peritoneal dialysis (PD) failure. The risk of death in the first six months is higher for older patients treated with urgent-start PD (USPD). However, there are still gaps in research on mortality and risk factors for death in this particular group of patients. We aimed to investigate mortality rates and risk factors for death in older patients with end-stage renal disease (ESRD) receiving USPD within and after six months of therapy...
April 15, 2024: BMC Geriatrics
https://read.qxmd.com/read/38622542/exploring-the-knowledge-and-skills-for-effective-family-caregiving-in-elderly-home-care-a-qualitative-study
#9
JOURNAL ARTICLE
Gebrezabher Niguse Hailu, Muntaha Abdelkader, Feven Asfaw, Hailemariam Atsbeha Meles
BACKGROUND: Family caregivers play a crucial role in providing physical, emotional, and social support to the elderly, allowing them to maintain their independence and stay in their preferred living environment. However, family caregivers face numerous challenges and require specific knowledge and skills to provide effective care. Therefore, understanding the knowledge and skills required for effective family caregiving in elderly home care is vital to support both the caregivers and the elderly recipients...
April 15, 2024: BMC Geriatrics
https://read.qxmd.com/read/38622502/targeted-metabolomic-profiles-of-serum-amino-acids-are-independently-correlated-with-malnutrition-in-older-adults
#10
JOURNAL ARTICLE
Xianghui Zhao, Li Meng, Daguang Wang, Jing Shi, Wenbin Wu, Guoqing Fan, Hong Shi, Jun Dong, Pulin Yu, Ruiyue Yang
BACKGROUND: Malnutrition is a common geriatric syndrome that is closely associated with adverse clinical outcomes and poses significant harm to older adults. Early assessment of nutritional status plays a crucial role in preventing and intervening in cases of malnutrition. However, there is currently a lack of measurable methods and biomarkers to evaluate malnutrition in older adults accurately. The aim of this study is to investigate the independent correlation between serum levels of amino acids and malnutrition in older adults, and to identify effective metabolomics biomarkers that can aid in the early detection of geriatric malnutrition...
April 15, 2024: BMC Geriatrics
https://read.qxmd.com/read/38609878/determinants-of-hospital-readmissions-in-older-people-with-dementia-a-narrative-review
#11
JOURNAL ARTICLE
Bria Browne, Khalid Ali, Elizabeth Ford, Naji Tabet
INTRODUCTION: Over 50% of hospitalised older people with dementia have multimorbidity, and are at an increased risk of hospital readmissions within 30 days of their discharge. Between 20-40% of these readmissions may be preventable. Current research focuses on the physical causes of hospital readmissions. However, older people with dementia have additional psychosocial factors that are likely to increase their risk of readmissions. This narrative review aimed to identify psychosocial determinants of hospital readmissions, within the context of known physical factors...
April 12, 2024: BMC Geriatrics
https://read.qxmd.com/read/38609875/predictors-of-major-adverse-cardiac-and-cerebrovascular-events-after-percutaneous-coronary-intervention-in-older-adults-a-systematic-review-and-meta-analysis
#12
JOURNAL ARTICLE
Arash Jalali, Ali Hassanzadeh, Mohammad Sadeq Najafi, Sepehr Nayebirad, Mohadese Dashtkoohi, Zahra Karimi, Akbar Shafiee
AIM: We systematically reviewed and meta-analyzed the predictors of major adverse cardiac and cerebrovascular events (MACE/MACCE) in older adults who underwent PCI. METHODS: Three databases, PubMed, Embase, and Scopus, were searched for observational studies considering the out-of-hospital MACE/MACCE in adults ≥ 60 years old with coronary artery disease (acute or chronic) who underwent PCI. Studies were eligible if they had determined at least two statistically significant predictors of MACE/MACCE by multivariable analysis...
April 12, 2024: BMC Geriatrics
https://read.qxmd.com/read/38609868/factors-impacting-clinical-data-and-documentation-quality-in-australian-aged-care-and-disability-services-a-user-centred-perspective
#13
JOURNAL ARTICLE
Gap Tshering, Lakkhina Troeung, Rebecca Walton, Angelita Martini
BACKGROUND: Research has highlighted a need to improve the quality of clinical documentation and data within aged care and disability services in Australia to support improved regulatory reporting and ensure quality and safety of services. However, the specific causes of data quality issues within aged care and disability services and solutions for optimisation are not well understood. OBJECTIVES: This study explored aged care and disability workforce (referred to as 'data-users') experiences and perceived root causes of clinical data quality issues at a large aged care and disability services provider in Western Australia, to inform optimisation solutions...
April 12, 2024: BMC Geriatrics
https://read.qxmd.com/read/38609867/effect-modification-of-polypharmacy-on-incident-frailty-by-chronic-kidney-disease-in-older-adults
#14
JOURNAL ARTICLE
Nina Mielke, Muhammad Helmi Barghouth, Anne-Katrin Fietz, Cédric Villain, Tim Bothe, Natalie Ebert, Elke Schaeffner
BACKGROUND: Frailty and polypharmacy are common conditions in older adults, especially in those with chronic kidney disease (CKD). Therefore, we analyzed the association of polypharmacy and incident frailty and the effect modification by CKD in very old adults. METHODS: In non-frail individuals within the Berlin Initiative (cohort) Study, polypharmacy (≥ 5 medications) was assessed according to multiple definitions based on the number of regular and on demand prescription and over the counter drugs, as well as vitamins and supplements...
April 12, 2024: BMC Geriatrics
https://read.qxmd.com/read/38609852/factors-affecting-hospital-admission-hospital-length-of-stay-and-new-discharge-destination-post-proximal-humeral-fracture-a-retrospective-audit
#15
JOURNAL ARTICLE
B R McDonald, S Vogrin, C M Said
BACKGROUND: Outcomes following proximal humeral fracture (PHF) may be impacted by a range of clinical, fracture and premorbid factors. The aim of this study was to examine factors impacting hospital admission; length of stay (LOS) and new discharge destination for patients presenting to hospital with PHF. METHODS: Retrospective audit conducted at a tertiary health service. Data was collected from adult patients presenting to hospital with a PHF over a 54-month period...
April 12, 2024: BMC Geriatrics
https://read.qxmd.com/read/38609838/the-effect-of-participation-in-support-groups-on-retirement-syndrome-in-older-adults
#16
JOURNAL ARTICLE
Sakineh Qorbani, Zahra Amrollah Majdabadi, Nasrin Nikpeyma, Shima Haghani, Sahar Keyvanloo Shahrestanaki, Sarieh Poortaghi
BACKGROUND: Retirement and aging are phenomena that often occur simultaneously and lead to various physical and psychological changes in older adults. Retirement syndrome consists of symptoms such as feelings of emptiness, loneliness, uselessness, lack of clear understanding of future conditions and dissatisfaction with one's performance after retirement. This phenomenon requires interventions to adapt to these changes. Considering the supportive role of nurses, the formation of support groups as an effective intervention in adapting to transitional stages is emphasized...
April 12, 2024: BMC Geriatrics
https://read.qxmd.com/read/38605336/lacto-ovo-vegetarian-diet-is-inversely-associated-with-the-osteosarcopenia-in-older-adults
#17
JOURNAL ARTICLE
Runnian Huang, Junwei Hu, Yi Li, Sijia Yang, Xin Li, Tianbo Hou, Zibo Ning, Chunhua Ma, Xiaoyue Yuan, Zheng Wang, Tiantian Zhang, Difei Wang
OBJECTIVE: Osteosarcopenia adversely affects the quality of life and physical health of older adults. We sought to explore the association between dietary patterns and osteosarcopenia in community-dwelling older adults. METHODS: This is a cross-sectional study from Northeast China, in which, we included older community adults aged 60 and above. Through face-to-face interviews, we collected dietary information from participants using a food frequency questionnaire...
April 11, 2024: BMC Geriatrics
https://read.qxmd.com/read/38605326/association-of-8-hydroxy-2-deoxyguanosine-with-motoric-cognitive-risk-in-elderly-chinese-people-rugao-longevity-and-aging-cross-sectional-study
#18
JOURNAL ARTICLE
Qingqing Dai, Yajun Ma, Chang Liu, Ruixue Zhao, Qi Chen, Weijia Chen, Xiaofeng Wang, Xiaoyan Jiang, Shujuan Li
BACKGROUND: Motor cognitive risk syndrome (MCR) represents a critical pre-dementia and disability state characterized by a combination of objectively measured slow walking speed and subjective memory complaints (SMCs). This study aims to identify risk factors for MCR and investigate the relationship between plasma levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG) and MCR among Chinese community-dwelling elderly populations. METHODS: A total of 1312 participants were involved in this study based on the data of the Rugao Longevity and Aging Study (RuLAS)...
April 11, 2024: BMC Geriatrics
https://read.qxmd.com/read/38600482/barriers-and-facilitators-to-care-for-agitation-and-or-aggression-among-persons-living-with-dementia-in-long-term-care
#19
JOURNAL ARTICLE
Britney Wong, Zahinoor Ismail, Jennifer Watt, Jayna Holroyd-Leduc, Zahra Goodarzi
BACKGROUND: Agitation and/or aggression affect up to 60% of persons living with dementia in long-term care (LTC). It can be treated via non-pharmacological and pharmacological interventions, but the former are underused in clinical practice. In the literature, there is currently a lack of understanding of the challenges to caring for agitation and/or aggression among persons living with dementia in LTC. This study assesses what barriers and facilitators across the spectrum of care exist for agitation and/or aggression among people with dementia in LTC across stakeholder groups...
April 11, 2024: BMC Geriatrics
https://read.qxmd.com/read/38600478/square-stepping-exercise-in-older-inpatients-in-early-geriatric-rehabilitation-a-randomized-controlled-pilot-study
#20
JOURNAL ARTICLE
Katja Fränzel, Jessica Koschate, Ellen Freiberger, Ryosuke Shigematsu, Tania Zieschang, Svenja Tietgen
BACKGROUND: Preservation of mobility and fall prevention have a high priority in geriatric rehabilitation. Square-Stepping Exercise (SSE) as an evaluated and standardized program has been proven to be an effective training for older people in the community setting to reduce falls and improve subjectively perceived health status. This randomized controlled trial (RCT), for the first time, examines SSE in the context of inpatient early geriatric rehabilitation compared to conventional physiotherapy (cPT)...
April 10, 2024: BMC Geriatrics
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