Zhenglu Wang, Lei Cao, Jianxi Wang, Hanlin Wang, Tingting Ma, Zhiqi Yin, Wenjuan Cai, Lei Liu, Tao Liu, Hengde Ma, Yamin Zhang, Zhongyang Shen, Hong Zheng
BACKGROUND: This study aims to construct and verify a nomogram model for microvascular invasion (MVI) based on hepatocellular carcinoma (HCC) tumor characteristics and differential protein expressions, and explore the clinical application value of the prediction model. METHODS: The clinicopathological data of 200 HCC patients were collected and randomly divided into training set and validation set according to the ratio of 7:3. The correlation between MVI occurrence and primary disease, age, gender, tumor size, tumor stage, and immunohistochemical characteristics of 13 proteins, including GPC3, CK19 and vimentin, were statistically analyzed...
March 27, 2023: BMC Gastroenterology