journal
https://read.qxmd.com/read/38778288/a-comprehensive-scoring-system-for-the-better-prediction-of-bowel-resection-in-pediatric-intussusception
#1
JOURNAL ARTICLE
Bingshan Xia, Guoqiang Chen, Qianyang Liu, Chengwei Yan, Peng Lu, Chunbao Guo
BACKGROUND: Intussusception presents a significant emergency that often necessitates bowel resection, leading to severe complications and management challenges. This study aims to investigate and establish a scoring system to enhance the prediction of bowel resection necessity in pediatric intussusception patients. METHODS: This retrospective study analyzed 660 hospitalized patients with intussusception who underwent surgical management at a pediatric hospital in Southwest China from April 2008 to December 2020...
May 22, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38778264/morning-light-treatment-for-inflammatory-bowel-disease-a-clinical-trial
#2
JOURNAL ARTICLE
Shirley Cohen-Mekelburg, Cathy A Goldstein, Muneer Rizvydeen, Zainab Fayyaz, Priya J Patel, Jeffrey A Berinstein, Shrinivas Bishu, Kelly C Cushing-Damm, Hyungjin Myra Kim, Helen J Burgess
BACKGROUND: Inflammatory bowel disease (IBD) affects over 3 million Americans and has a relapsing and remitting course with up to 30% of patients experiencing exacerbations each year despite the availability of immune targeted therapies. An urgent need exists to develop adjunctive treatment approaches to better manage IBD symptoms and disease activity. Circadian disruption is associated with increased disease activity and may be an important modifiable treatment target for IBD. Morning light treatment, which advances and stabilizes circadian timing, may have the potential to improve IBD symptoms and disease activity, but no studies have explored these potential therapeutic benefits in IBD...
May 22, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38778244/preliminary-study-on-the-diagnostic-value-of-leap-2-and-ck18-in-biopsy-proven-mafld
#3
JOURNAL ARTICLE
Zhi Liu, Qiao Ren, Hongying Mu, Yuping Zeng, Zhenmei An, He He
Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) has become the leading cause of chronic liver disease. Liver biopsy, as the diagnostic gold standard, is invasive and has sampling bias, making it particularly important to search for sensitive and specific biomarkers for diagnosis. Cytokeratin 18 (CK18) M30 and M65 are products of liver cell apoptosis and necrosis, respectively, and liver-expressed antimicrobial peptide 2 (LEAP-2) is a related indicator of glucose and lipid metabolism. Correlation studies have found that all three indicators positively correlate with the liver enzymes alanine aminotransferase (ALT) and aspartate aminotransferase (AST)...
May 22, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38773485/predictive-value-of-preoperative-ct-enhancement-rate-and-ct-perfusion-parameters-in-colorectal-cancer
#4
JOURNAL ARTICLE
Ze-Mao Li, Wei Zhou, Li Feng, Hui-Ying Zhang, Wei-Bin Chen
BACKGROUND: Angiogenesis is a critical step in colorectal cancer growth, progression and metastasization. CT are routine imaging examinations for preoperative clinical evaluation in colorectal cancer patients. This study aimed to investigate the predictive value of preoperative CT enhancement rate (CER) and CT perfusion parameters on angiogenesis in colorectal cancer, as well as the association of preoperative CER and CT perfusion parameters with serum markers. METHODS: This retrospective analysis included 42 patients with colorectal adenocarcinoma...
May 21, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38773451/evaluating-the-diagnostic-accuracy-of-heat-shock-proteins-and-their-combination-with-alpha-fetoprotein-in-the-detection-of-hepatocellular-carcinoma-a-meta-analysis
#5
JOURNAL ARTICLE
Dan Xiang, Lifang Fu, Ying Yang, ChengJiang Liu, Yong He
BACKGROUND: A growing body of research suggests that heat shock proteins (HSPs) may serve as diagnostic biomarkers for hepatocellular carcinoma (HCC), but their results are still controversial. This meta-analysis endeavors to evaluate the diagnostic accuracy of HSPs both independently and in conjunction with alpha-fetoprotein (AFP) as novel biomarkers for HCC detection. METHODS: Pooled statistical indices, including sensitivity, specificity, diagnostic odds ratio (DOR), positive likelihood ratio (PLR), and negative likelihood ratio (NLR) with 95% confidence intervals (CI), were computed to assess the diagnostic accuracy of HSPs, AFP, and their combinations...
May 21, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38773435/widespread-use-of-proton-pump-inhibitors-or-potassium-competitive-acid-blocker-has-changed-the-status-of-gastrointestinal-bleeding-in-patients-with-ischemic-heart-disease-real-world-data-from-high-volume-centers
#6
MULTICENTER STUDY
Shun Sasaki, Kazuhiro Ota, Makoto Sanomura, Yosuke Mori, Hironori Tanaka, Akitoshi Hakoda, Noriaki Sugawara, Taro Iwatsubo, Yuki Hirata, Kazuki Kakimoto, Hideaki Morita, Wataru Nagamatsu, Masaaki Hoshiga, Toshihisa Takeuchi, Kazuhide Higuchi, Hiroki Nishikawa
BACKGROUND: Although proton pump inhibitors (PPIs) or potassium-competitive acid blocker (PCAB) are useful in peptic ulcer prevention, their efficacy in preventing other gastrointestinal bleeding remains unclear. This study aimed to identify the status of gastrointestinal bleeding in the modern era when PPIs are widely used. METHODS: This study included patients who underwent percutaneous coronary intervention (PCI) between 2018 and 2019 at two high-volume centers...
May 21, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38773426/the-prevalence-and-severity-of-upper-gastrointestinal-complications-among-patients-with-chronic-diseases-a-cross-sectional-study-from-palestine
#7
JOURNAL ARTICLE
Rowa Al Ramahi, Deema Tumeh
BACKGROUND: Many old people have at least one chronic disease. As a result, multiple drugs should be used. Gastrointestinal complications may occur because of the harmful effects of these chronic drugs on the stomach. The study aimed to assess the prevalence of upper gastrointestinal complications in patients taking chronic medications, the severity of these symptoms, and whether they take any gastro-protective drugs or not. METHODOLOGY: This was a cross-sectional study through face-to-face questionnaires from internal outpatient clinics at a specialized hospital...
May 21, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38769494/inside-stent-placement-is-suitable-for-preoperative-biliary-drainage-in-patients-with-perihilar-cholangiocarcinoma
#8
COMPARATIVE STUDY
Reiko Yamada, Naohisa Kuriyama, Takamitsu Tanaka, Kenji Nose, Yoshifumi Nakamura, Tetsuro Miwata, Junya Tsuboi, Shugo Mizuno, Hayato Nakagawa
BACKGROUND/PURPOSE: Endoscopic biliary stenting (EBS) is commonly used for preoperative drainage of localized perihilar cholangiocarcinoma (LPHC). This study retrospectively compared the utility of inside stent (IS) and conventional stent (CS) for preoperative EBS in patients with LPHC. METHODS: EBS was performed in 56 patients with LPHC. EBS involved the placement of a CS (n = 32) or IS (n = 24). Treatment outcomes were compared between these two groups...
May 20, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38762503/medical-radiation-exposure-in-inflammatory-bowel-disease-an-updated-meta-analysis
#9
JOURNAL ARTICLE
Chao Lu, Xin Yao, Mosang Yu, Xinjue He
BACKGROUND: There have been previous studies and earlier systematic review on the relationship between inflammatory bowel disease (IBD) and radiation exposure. With the diversification of current test methods, this study intended to conduct a meta-analysis to evaluate the IBD radiation exposure in recent years. METHODS: Three databases (PUBMED, EMBASE, and MEDICINE) for relevant literature up to May 1, 2023 were searched. The statistical data meeting requirements were collated and extracted...
May 18, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38760726/clip-and-snare-method-with-a-pre-looping-technique-versus-conventional-method-in-the-treatment-of-precancerous-lesion-and-early-gastric-cancer-a-retrospective-study
#10
COMPARATIVE STUDY
Ruichong Deng, Jiatong Wu, Defeng Li, Benhua Wu, Ruiyue Shi, Yanhui Tian, Jun Yao, Li-Sheng Wang
BACKGROUND: Low grade intraepithelial neoplasia (LGIN) and high grade intraepithelial neoplasia (HGIN) are potential precancerous lesion of gastric neoplasms. Endoscopic submucosal dissection (ESD) is the first option for the treatment of precancerous lesion and early gastric cancer (EGC). Traction is an effective method to improve efficiency, and reduce complications during ESD. In this study, we shared a useful traction method using the clip-and-snare method with a pre-looping technique (CSM-PLT) for precancerous lesion and EGC...
May 17, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38760713/proton-pump-inhibitor-therapy-after-transcatheter-angiography-in-refractory-nonvariceal-acute-upper-gastrointestinal-bleeding-patients-a-cohort-study
#11
JOURNAL ARTICLE
Xue Xiao, Xinbing Liu, Hailin Yan, Xiaocun Xing, Xuefeng Luo, Jinlin Yang
BACKGROUND: Transcatheter angiography (TA) could help to diagnose and treat refractory nonvariceal upper gastrointestinal bleeding (NVUGIB). Proton pump inhibitors (PPIs) are the key medication for reducing the rebleeding rate and mortality and are usually continued after TA. It is unknown whether high-dose PPIs after TA are more effective than the standard regimen. METHODS: We retrospectively collected data from patients who received TA because of refractory NVUGIB from 2010 to 2020 at West China Hospital...
May 17, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38760704/the-association-between-dietary-vitamin-b1-intake-and-constipation-a-population-based-study
#12
JOURNAL ARTICLE
Wenyi Du, Lingchen Lu, Yuxuan Liu, Yuxin Yan, Rui La, Qian Wu, Jie Xu, Xiaojun Zhou
BACKGROUND: Numerous researches have indicated a correlation between the intake of dietary micronutrients and the occurrence of constipation. Nevertheless, the correlation between constipation and vitamin B1 remains uninvestigated. The main aim of this research was to examine the association between chronic constipation and the consumption of vitamin B1 in the diet among adult participants of the National Health and Nutrition Examination Survey (NHANES). METHODS: This study used data from the NHANES, a survey on health and nutrition conducted between 2005 and 2010...
May 17, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38760691/the-association-between-night-eating-syndrome-and-gerd-symptoms-among-university-students-at-an-najah-national-university-in-palestine-a-cross-sectional-study
#13
JOURNAL ARTICLE
Mohammad Taleb Abed, Eyad Sayyed, Obada Yamak, Qusay Abdoh, Manal Badrasawi
BACKGROUND: Night eating syndrome (NES) is a kind of eating disorder. NES association with gastroesophageal reflux disease (GERD) symptoms among university students is still not fully understood. We aimed to determine the relationship between NES and the presence of GERD symptoms among university students at An-Najah National University in Palestine. METHODS: This study involved undergraduate students from An-Najah National University. The data were collected through online surveys from November to December 2023...
May 17, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38760679/clinical-and-health-care-utilization-variables-can-predict-90-day-hospital-re-admission-in-adults-with-crohn-s-disease-for-point-of-care-risk-evaluation
#14
JOURNAL ARTICLE
C Dziegielewski, S Gupta, J Begum, M Pugliese, J Lombardi, Kelly E, McCurdy Jd, R Sy, Saloojee N, Ramsay T, Benchimol Ei, Murthy Sk
BACKGROUND: Hospital re-admission for persons with Crohn's disease (CD) is a significant contributor to morbidity and healthcare costs. We derived prediction models of risk of 90-day re-hospitalization among persons with CD that could be applied at hospital discharge to target outpatient interventions mitigating this risk. METHODS: We performed a retrospective study in persons with CD admitted between 2009 and 2016 for an acute CD-related indication. Demographic, clinical, and health services predictor variables were ascertained through chart review and linkage to administrative health databases...
May 17, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38755577/immunohistochemistry-and-real-time-polymerase-chain-reaction-importance-in-the-diagnosis-of-intestinal-tuberculosis-in-a-peruvian-population
#15
JOURNAL ARTICLE
Fernando Arevalo, Soledad Rayme, Rocío Ramírez, Romy Rolando, Jaime Fustamante, Mario Monteghirfo, Rocio Chavez, Eduardo Monge
INTRODUCTION: The diagnosis of intestinal tuberculosis is challenging even nowadays. This study aims to report the positivity rates of new diagnostic methods such as immunohistochemistry and Real-Time Polymerase Chain Reaction in patients with intestinal tuberculosis, as well as describe the pathological and endoscopic features of intestinal tuberculosis in our population. METHODS: This was a retrospective observational study conducted in patients diagnosed with intestinal tuberculosis, between 2010 to 2023 from the Hospital Nacional Daniel Alcides Carrion and a Private Pathology Center, both located in Peru...
May 16, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38755550/serrated-polyposis-syndrome-defining-the-epidemiology-and-predicting-the-risk-of-dysplasia
#16
JOURNAL ARTICLE
Natalie R Dierick, Brian D Nicholson, Thomas R Fanshawe, Praka Sundaralingam, Stuart N Kostalas
BACKGROUND: Serrated polyposis syndrome is the most common polyposis syndrome that has neoplastic potential. However, the natural history, genetic basis, and risk of dysplasia and neoplasia of serrated polyposis syndrome are incompletely understood. The objective of this study is to define the epidemiology of serrated polyposis syndrome. Using this data, we aim to evaluate candidate variables for predicting the risk of dysplasia and neoplasia in sessile serrated lesions found in serrated polyposis syndrome patients...
May 16, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38750425/sex-difference-in-the-associations-among-risk-factors-with-gastroesophageal-reflux-disease-in-a-large-taiwanese-population-study
#17
JOURNAL ARTICLE
Chien-Chieh Lin, Jiun-Hung Geng, Pei-Yu Wu, Jiun-Chi Huang, Huang-Ming Hu, Szu-Chia Chen, Chao-Hung Kuo
BACKGROUND: Gastroesophageal reflux disease (GERD) is a common global health issue. Previous studies have revealed a higher prevalence of GERD in females than in males, however few studies have investigated sex differences in the risk factors associated with GERD. Therefore, the aim of this population-based study was to examine sex differences in the risk factors for GERD in a large cohort of over 120,000 Taiwanese participants. METHODS: We enrolled 121,583 participants (male: 43,698; female: 77,885; mean age 49...
May 15, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38745162/long-term-prognosis-after-endoscopic-submucosal-dissection-for-esophageal-cancer-in-older-adult-patients
#18
JOURNAL ARTICLE
Hirona Konishi, Yuji Urabe, Takeo Nakamura, Kazuki Ishibashi, Junichi Mizuno, Motomitsu Fukuhara, Takeshi Takasago, Hidenori Tanaka, Akiyoshi Tsuboi, Ken Yamashita, Yuichi Hiyama, Hidehiko Takigawa, Takahiro Kotachi, Ryo Yuge, Akira Ishikawa, Shiro Oka
BACKGROUND: The validity of endoscopic submucosal dissection (ESD) for esophageal squamous cell carcinoma (ESCC) in older individuals with comorbidities remains unclear. Therefore, this study evaluated the safety and efficacy of ESD and additional treatment for ESCC in older adult patients. METHODS: The clinicopathological characteristics and clinical outcomes of 398 consecutive older adult patients (≥ 65 years) with 505 lesions who underwent ESD for ESCC at the Hiroshima University Hospital between September 2007 and December 2019 were retrospectively evaluated...
May 14, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38745150/hepatic-recruitment-of-myeloid-derived-suppressor-cells-upon-liver-injury-promotes-both-liver-regeneration-and-fibrosis
#19
JOURNAL ARTICLE
Qiongwen Zhang, Ting Yu, Huaicheng Tan, Huashan Shi
BACKGROUND: The liver regeneration is a highly complicated process depending on the close cooperations between the hepatocytes and non-parenchymal cells involving various inflammatory cells. Here, we explored the role of myeloid-derived suppressor cells (MDSCs) in the processes of liver regeneration and liver fibrosis after liver injury. METHODS: We established four liver injury models of mice including CCl4 -induced liver injury model, bile duct ligation (BDL) model, concanavalin A (Con A)-induced hepatitis model, and lipopolysaccharide (LPS)-induced hepatitis model...
May 14, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38745130/risk-factors-for-delayed-colorectal-postpolypectomy-bleeding-a-meta-analysis
#20
JOURNAL ARTICLE
Xuzhen Zhang, Xiaoxing Jiang, Liang Shi
BACKGROUND: To systematically analyze risk factors for delayed postpolypectomy bleeding (DPPB) in colorectum. METHODS: We searched seven large databases from inception to July 2022 to identify studies that investigated risk factors for DPPB. The effect sizes were expressed by relative risk (RR) and 95% confidence interval (95% CI). The heterogeneity was analyzed by calculating I2 values and performing sensitivity analyses. RESULTS: A total of 15 articles involving 24,074 subjects were included in the study...
May 14, 2024: BMC Gastroenterology
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