Xiao-Jian He, Xiao-Ling Wang, Chuan-Shen Jiang, Dong-Gui Hong, Hai-Lan Lin, Yun-Ping Zheng, Han Li, Xin-Jiang Chen, Jian-Xiao Huang, Ling-Shuang Dai, Mei-Yan Liu, Bao-Xiang Luo, Dong-Liang Li, Da-Zhou Li, Wen Wang
BACKGROUND: Novel endoscopic techniques used in the treatment of gastric lesions with local submucosal fibrosis need preclinical evaluation and training due to safety limitations. Therefore, the purpose of our study was to establish an animal model of gastric local fibrotic target lesions and assess its feasibility in the evaluation and training of endoscopic techniques. METHODS: In six experimental beagles, a 50% glucose solution was injected into three submucosal areas of the fundus, body, and antrum of the stomach to create gastric local fibrotic target lesions (experimental group)...
November 27, 2023: BMC Gastroenterology