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BMC Anesthesiology

Qiang Zhu, Li Li, Zhaoyun Yang, Jinmei Shen, Rong Zhu, Yu Wen, Wenwu Cai, Lei Liu
BACKGROUND: Quadratus lumborum (QL) block is increasingly being used as a new abdominal nerve block technique. In some studies of mid and lower abdominal and hip analgesia, continuous QL block achieved favorable outcomes as an alternative to continuous intravenous analgesia with opioids. However, the use of continuous QL block for upper abdominal pain is less well characterized. This study aimed to investigate the effects of continuous anterior QL block (CQLB) on postoperative pain and recovery in patients undergoing open liver resection...
February 18, 2019: BMC Anesthesiology
F Lehmann, J Rau, B Malcolm, M Sander, C von Heymann, T Moormann, T Geyer, F Balzer, K D Wernecke, L Kaufner
BACKGROUND: Adult cardiac surgery is often complicated by elevated blood losses that account for elevated transfusion requirements. Perioperative bleeding and transfusion of blood products are major risk factors for morbidity and mortality. Timely diagnostic and goal-directed therapies aim at the reduction of bleeding and need for allogeneic transfusions. METHODS: Single-centre, prospective, randomized trial assessing blood loss and transfusion requirements of 26 adult patients undergoing elective cardiac surgery at high risk for perioperative bleeding...
February 18, 2019: BMC Anesthesiology
Panu Uusalo, Mirjam Lehtinen, Eliisa Löyttyniemi, Tuula Manner, Mika Scheinin, Teijo I Saari
BACKGROUND: Barbiturates are commonly used in ambulatory sedation of pediatric patients. However, use of barbiturates involve risks of respiratory complications. Dexmedetomidine, a highly selective α2 -adrenoceptor agonist, is increasingly used for pediatric sedation. Premedication with intranasal (IN) dexmedetomidine offers a non-invasive and efficient possibility to sedate pediatric patients undergoing magnetic resonance imaging (MRI). Our hypothesis was that dexmedetomidine would reduce barbiturate requirements in procedural sedation...
February 13, 2019: BMC Anesthesiology
Gergely H Fodor, Walid Habre, Adam L Balogh, Roberta Südy, Barna Babik, Ferenc Peták
BACKGROUND: Crystalloids are first line in fluid resuscitation therapy, however there is a lack of evidence-based recommendations on the volume to be administered. Therefore, we aimed at comparing the systemic hemodynamic and respiratory effects of volume replacement therapy with a 1:1 ratio to the historical 1:3 ratio. METHODS: Anesthetized, ventilated rats randomly included in 3 groups: blood withdrawal and replacement with crystalloid in 1:1 ratio (Group 1, n = 11), traditional 1:3 ratio (Group 3, n = 12) and a control group with no interventions (Group C, n = 9)...
February 13, 2019: BMC Anesthesiology
Fuxi Song, Chunmiao Ye, Feng Qi, Ping Zhang, Xuexiang Wang, Yanfeng Lü, Alejandro Fernandez-Escobar, Chao Zheng, Liang Li
The authors have retracted this article.
February 13, 2019: BMC Anesthesiology
Roser Vives, Diana Fernandez-Galinski, Francisca Gordo, Alberto Izquierdo, Joan C Oliva, Carmen Colilles, Caridad Pontes
BACKGROUND: Bupivacaine and levobupivacaine have similar pharmacokinetic and pharmacodynamic characteristics, and are used regularly in spinal anesthesia. Whether potential differences in their hemodynamic and anesthetic profiles could determine a differential risk of complications in elderly subjects, is controversial. The main objective was to compare the effects of intrathecally administered levobupivacaine (LB) versus bupivacaine (B), on regional cerebral O2 saturation during spinal anesthesia, cognitive status and neurological complications in elderly patients undergoing surgery for hip fracture...
January 31, 2019: BMC Anesthesiology
Stefan J Schaller, Felix P Kappler, Claudia Hofberger, Jens Sattler, Richard Wagner, Gerhard Schneider, Manfred Blobner, Karl-Georg Kanz
BACKGROUND: Although pain treatment is an important objective in prehospital emergency medicine the incidence of oligoanalgesia is still high in prehospital patients. Given that prehospital emergency medicine in Germany is open for physicians of any speciality, the prehospital pain treatment may differ depending on the primary medical education. Aim of this study was to explore the difference in pain treatment between surgeons and anaesthesiologists in a physician staffed emergency medical service...
January 31, 2019: BMC Anesthesiology
Stefan Felix Ehrentraut, Barbara Schroll, Stefan Lenkeit, Heidi Ehrentraut, Christian Bode, Stefan Kreyer, Florian Kögl, Felix Lehmann, Thomas Muders, Martin Scholz, Claudia Strater, Folkert Steinhagen, Nils Ulrich Theuerkauf, Carsten Weißbrich, Christian Putensen, Jens-Christian Schewe
BACKGROUND: Extra Corporeal Membrane Oxygenation (ECMO) has become an accepted treatment option for severely ill patients. Due to a limited availability of ECMO support therapy, patients must often be transported to a specialised centre before or after cannulation. According to the ELSO guidelines, an ECMO specialist should be present for such interventions. Here we describe the safety and efficacy of a reduced team approach involving one anaesthesiologist, experienced in specialised intensive care medicine, and a specialised critical care nurse...
January 31, 2019: BMC Anesthesiology
Michael St Pierre, Frederick Krischke, Bjoern Luetcke, Joachim Schmidt
BACKGROUND: Aspiration is a main contributor to morbidity and mortality in anaesthesia. The ideal patient positioning for rapid sequence induction remains controversial. A head-down tilt and full cervical spine extension (Sellick) might prevent aspiration but at the same time compromise airway management. We aimed to determine the influence of three different positions during induction of general anaesthesia on the volume of aspirate and on participants' airway management. METHODS: Eighty-four anaesthetic trainees and consultants participated in a prospective randomised simulation study...
January 24, 2019: BMC Anesthesiology
Heleen J Blussé van Oud-Alblas, Margreke J E Brill, Mariska Y M Peeters, Dick Tibboel, Meindert Danhof, Catherijne A J Knibbe
BACKGROUND: In adolescents limited data are available on the pharmacokinetics (PK) and pharmacodynamics (PD) of propofol. In this study we derived a PK-PD model for propofol in adolescents undergoing idiopathic scoliosis surgery with an intraoperative wake-up test with reinduction of anesthesia using both Bispectral Index (BIS) and composite A-line ARX index (cAAI) as endpoints. METHODS: Fourteen adolescents (9.8-20.1 years) were evaluated during standardized propofol-remifentanil anesthesia for idiopathic scoliosis surgery with an intraoperative wake-up test with reinduction of anesthesia...
January 22, 2019: BMC Anesthesiology
Wenxi Tang, Penghui Wei, Jiapeng Huang, Na Zhang, Haipeng Zhou, Jinfeng Zhou, Qiang Zheng, Jianjun Li, Zhigang Wang
BACKGROUND: The asleep-awake-asleep (AAA) technique and laryngeal mask airway (LMA) is a common general anesthesia technique for deep brain stimulation (DBS) surgery. However, the LMA is not always the ideal artificial airway. In this report, we presented our experiences with nasotracheal intubation-extubation-intubation (IEI) and AAA techniques in DBS surgery for Parkinson's disease (PD) patients to meet the needs of surgery and ensure patients' safety and comfort. CASE PRESENTATION: Three PD patients scheduled for DBS surgery had to receive general anesthesia for various reasons...
January 17, 2019: BMC Anesthesiology
Beibei Dong, Yongyan Yang, Zhishen Zhang, Keliang Xie, Lin Su, Yonghao Yu
BACKGROUND: Ischemia-reperfusion (I/R) is a critical pathophysiological basis of cognitive dysfunction caused by ischemia stroke. Heme-oxygenase-1 (HO-1) is the rate-limiting enzyme for the elimination of excessive free heme by combining with hemopexin (HPX), a plasma protein that contributes to eliminating excessive free heme during ischemia stroke. This study aimed to elucidate whether HPX could alleviate cognitive dysfunction in rats subjected to cerebral I/R. METHODS: Rats were randomly divided into five groups: sham, MCAO, Vehicle, HPX and HPX + protoporphyrin IX (ZnPPIX)...
January 15, 2019: BMC Anesthesiology
Yoko Okumura, Masahiro Okuda, Aiji Sato Boku, Naoko Tachi, Mayumi Hashimoto, Tomio Yamada, Masahiro Yamada
BACKGROUND: Airway Scope (AWS) with its plastic blade does not require a head-tilt or separate laryngoscopy to guide intubations. Therefore, we hypothesized that its use would reduce the intubation time (IT) and the frequency of airway complication events when compared with the use of Macintosh Laryngoscope (ML) for infants with cleft lip and palate (CLP). METHODS: The parents of all patients provided written consents; we enrolled 40 infants with CLP (ASA-PS 1)...
January 12, 2019: BMC Anesthesiology
Dan Huang, Linjie Zhu, Jie Chen, Jie Zhou
BACKGROUND: Anticoagulant therapy during pregnancy is widely used due to the increasing awareness of maternal hypercoagulability. Few studies have reported the use of minimally invasive spinal anesthesia in these parturients. The objective of this study was to evaluate the safety and feasibility of minimally invasive spinal anesthesia in parturients with anticoagulation therapy undergoing cesarean section. METHODS: This was a randomized, controlled study conducted in 239 parturients using anticoagulants and undergoing selective cesarean section...
January 12, 2019: BMC Anesthesiology
Tzu-Yao Hung, Li-Wei Lin, Yu-Hang Yeh, Yung-Cheng Su, Chieh-Hung Lin, Ten-Fang Yang
BACKGROUND: The Cormack-Lehane (C-L) grade III airway is considered to be a challenging airway to intubate and is associated with a poor intubation success rate. The purpose of this study was to investigate whether the holding position, shapes, bend angles of the endotracheal tube (ET) and the stylet-assisted lifting of the epiglottis could improve the success rate of intubation. METHODS: Thirty-two participants, 26 physicians, 2 residents, and 4 nurse practitioners, with 12...
January 10, 2019: BMC Anesthesiology
H-G Topf, E R Strasser, G Breuer, W Rascher, M Rauh, F B Fahlbusch
BACKGROUND: Hemorrhage and blood loss are still among the main causes of preventable death. Global hemostatic assays are useful point-of-care test (POCT) devices to rapidly detect cumulative effects of plasma factors and platelets on coagulation. Thromboelastography (TEG) and Thromboelastometry (ROTEM) are established methods in many anesthesiological departments for guided hemostatic treatment. However, von Willebrand disease remains undetected by standard ROTEM, especially during emergency care, despite being the most prevalent congenital hemostatic disorder...
January 10, 2019: BMC Anesthesiology
Xiao-Dong Zhou, Wei-Hua Dong, Chu-Huan Zhao, Xia-Fei Feng, Wei-Wei Wen, Wen-Yi Tu, Meng-Xing Cai, Tian-Cheng Xu, Qiang-Li Xie
BACKGROUND: This study aimed at developing and validating a scoring model to stratify critically ill patients after cardiac surgery based on risk for dysphagia, a common but often neglected complication. METHODS: Data were prospectively collected and analyzed from January 2016 to June 2017 from 395 consecutive post cardiac surgery patients at the cardiac care unit (CCU) at a single center; 103 (26.1%) developed dysphagia. Univariate and multivariate logistic analyses were used to identify independent predictors for dysphagia...
January 10, 2019: BMC Anesthesiology
Jong Chan Kim, Yumin Ki, Jihee Kim, So Woon Ahn
BACKGROUND: Several methods have been used to predict difficult tracheal intubation. Among recently suggested methods, the upper lip bite test (ULBT) could serve as a good predictor. Soft tissue and skeletal hard tissue profiles are affected by many factors including ethnicity. We aimed to assess the clinical utility of the ULBT in Koreans while considering ethnic differences. METHODS: Three-hundred-forty-four Korean patients undergoing general anesthesia with orotracheal intubation were included...
January 10, 2019: BMC Anesthesiology
Wei Chao Li, Hong Gao, Ju Gao, Zi Jun Wang
BACKGROUND: Reperfusion ventricular arrhythmia (RA) associated with hypothermic ischaemic storage is increasingly recognized as a substantial contributor to adverse consequences after heart transplantation. Ischemia- or hypothermia-induced gap junction (GJ) remodelling is closely linked to RA. Reducing GJ remodelling contributes to RA attenuation and is important in heart transplantation. However, sevoflurane has an antiarrhythmic effect associated with the connexin 43 (Cx43) protein that has not yet been fully established...
January 8, 2019: BMC Anesthesiology
Yuan Zhang, Hong-Guang Bao, Yun-Luo Lv, Yan-Na Si, Liu Han, Hong-Yu Wang, Yu-Jie Gao, Wei-Qing Jiang, Chen Zhang
BACKGROUND: It has been reported that postoperative cognitive dysfunction (POCD) is correlated with the degeneration of the central nervous system, oxidative stress, inflammation, and endocrine and immune dysfunction. Increased age, predisposed comorbidity, long surgery time, and prolonged stay in the intensive care unit have been reported to be risk factors for developing POCD for cardiac surgery. In the present study, the risk factors of early POCD after colorectal surgery were investigated...
January 8, 2019: BMC Anesthesiology
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