journal
https://read.qxmd.com/read/38627666/seizures-in-febrile-children-with-sars-cov-2-infection-clinical-features-short-term-follow-up
#1
JOURNAL ARTICLE
Jipeng Jiang, Zhengsong Shen, Jie Cao
BACKGROUND: As the Omicron variant of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerges, the neurological manifestations correlated with this epidemic have garnered increasing attention. This study was primarily intended to compare seizures in febrile children with and without SARS-CoV-2 infection and to conduct short-term follow-up of the SARS-CoV-2-infected patients. METHODS: Retrospective analysis of patients admitted to the Children's Hospital of Chongqing Medical University for fever and seizures between October 1 and December 30, 2022...
April 17, 2024: BMC Pediatrics
https://read.qxmd.com/read/38627752/nomogram-for-predicting-early-hypophosphatemia-in-term-infants
#2
JOURNAL ARTICLE
Wan Tao, Shina Zhan, Yingjie Shen, Tianjiao Zhao, Feitian Li, Miao Gao, Tingting Yang, Jinqian Yu
BACKGROUND: Physiological processes rely on phosphate, which is an essential component of adenosine triphosphate (ATP). Hypophosphatasia can affect nearly every organ system in the body. It is crucial to monitor newborns with risk factors for hypophosphatemia and provide them with the proper supplements. We aimed to evaluate the risk factors and develop a nomogram for early hypophosphatemia in term infants. METHODS: We conducted a retrospective study involving 416 term infants measured serum phosphorus within three days of birth...
April 16, 2024: BMC Pediatrics
https://read.qxmd.com/read/38627645/the-effect-of-maternal-voice-and-non-nutritional-sucking-on-repeated-procedural-pain-of-heel-prick-in-neonates-a-quasi-experimental-study
#3
JOURNAL ARTICLE
Yushuang Chen, Leshan Zhou, Yanjuan Tan
BACKGROUND: Neonates in the neonatal intensive care unit undergo frequent painful procedures. It is essential to reduce pain using safe and feasible methods. PURPOSE: To evaluate the effects of non-nutritional sucking, mother's voice, or non-nutritional sucking combined with mother's voice on repeated procedural pain in hospitalized neonates. METHODS: A quasi-experimental study was conducted in which 141 neonates were selected in a hospital in Changsha, China...
April 16, 2024: BMC Pediatrics
https://read.qxmd.com/read/38622583/the-effect-of-respiratory-muscle-training-on-children-and-adolescents-with-cystic-fibrosis-a-systematic-review-and-meta-analysis
#4
JOURNAL ARTICLE
WenQian Cai, Meng Li, Yi Xu, Mei Li, JiaNan Wang, YaHui Zuo, JinJin Cao
BACKGROUND: Cystic fibrosis is a chronic genetic disease that can affect the function of the respiratory system. Previous reviews of the effects of respiratory muscle training in people with cystic fibrosis are uncertain and do not consider the effect of age on disease progression. This systematic review aims to determine the effectiveness of respiratory muscle training in the clinical outcomes of children and adolescents with cystic fibrosis. METHODS: Up to July 2023, electronic databases and clinical trial registries were searched...
April 15, 2024: BMC Pediatrics
https://read.qxmd.com/read/38622552/critically-ill-children-with-sars-cov-2-omicron-infection-at-a-national-children-medical-center-guangdong-china
#5
JOURNAL ARTICLE
Fen Lin, Dao-Ju Jiang, Song Zhang, Zhe Yang, Hua-Song Zeng, Zhi-Ping Liu, Li-Ye Yang
BACKGROUND: SARS-CoV-2 infection is described as asymptomatic, mild, or moderate disease in most children. SARS-CoV-2 infection related death in children and adolescents is rare according to the current reports. COVID-19 cases increased significantly in China during the omicron surge, clinical data regarding pediatric critical patients infected with the omicron variant is limited. In this study, we aim to provide an overview of the clinical characteristics and outcomes of critically ill children admitted to a national children's medical center in Guangdong Province, China, during the outbreak of the omicron variant infection...
April 15, 2024: BMC Pediatrics
https://read.qxmd.com/read/38622515/systemic-lupus-erythematosus-combined-with-wilson-s-disease-a-case-report-and-literature-review
#6
REVIEW
Zhenle Yang, Qian Li, Suwen Liu, Zihan Zong, Lichun Yu, Shuzhen Sun
BACKGROUND: Systemic lupus erythematosus (SLE) and Wilson's disease (WD) are both systemic diseases that can affect multiple organs in the body. The coexistence of SLE and WD is rarely encountered in clinical practice, making it challenging to diagnose. CASE REPORT: We present the case of a 9-year-old girl who initially presented with proteinuria, haematuria, pancytopenia, hypocomplementemia, and positivity for multiple autoantibodies. She was diagnosed with SLE, and her blood biochemistry showed elevated liver enzymes at the time of diagnosis...
April 15, 2024: BMC Pediatrics
https://read.qxmd.com/read/38605404/delineating-morbidity-patterns-in-preterm-infants-at-near-term-age-using-a-data-driven-approach
#7
JOURNAL ARTICLE
Octavia-Andreea Ciora, Tanja Seegmüller, Johannes S Fischer, Theresa Wirth, Friederike Häfner, Sophia Stoecklein, Andreas W Flemmer, Kai Förster, Alida Kindt, Dirk Bassler, Christian F Poets, Narges Ahmidi, Anne Hilgendorff
BACKGROUND: Long-term survival after premature birth is significantly determined by development of morbidities, primarily affecting the cardio-respiratory or central nervous system. Existing studies are limited to pairwise morbidity associations, thereby lacking a holistic understanding of morbidity co-occurrence and respective risk profiles. METHODS: Our study, for the first time, aimed at delineating and characterizing morbidity profiles at near-term age and investigated the most prevalent morbidities in preterm infants: bronchopulmonary dysplasia (BPD), pulmonary hypertension (PH), mild cardiac defects, perinatal brain pathology and retinopathy of prematurity (ROP)...
April 11, 2024: BMC Pediatrics
https://read.qxmd.com/read/38605385/association-between-dietary-selenium-and-zinc-intake-and-risk-of-dilated-cardiomyopathy-in-children-a-case-control-study
#8
JOURNAL ARTICLE
Maryam Aryafar, Mohammad Mahdavi, Hossein Shahzadi, Yeganeh Rajabpour Ranjbar, Mohammad Hassan Sohouli, Sina Afzal, Asal Neshatbini Tehrani, Danial Fotros, Ghazal Daftari
BACKGROUND: Dilated cardiomyopathy (DCMP) is characterized by the enlargement and weakening of the heart and is a major cause of heart failure in children. Infection and nutritional deficiencies are culprits for DCMP. Zinc is an important nutrient for human health due to its anti-oxidant effect that protects cell against oxidative damage. This case-control study aimed to investigate the relationship between dietary intake of zinc and selenium and the risk of DCMP in pediatric patients...
April 11, 2024: BMC Pediatrics
https://read.qxmd.com/read/38605324/the-timing-of-minimally-invasive-surgery-for-prenatally-diagnosed-choledochal-cysts
#9
JOURNAL ARTICLE
Shiwen Pan, Wei Li, Huan Chen, Changgui Lu
OBJECTIVE: There are no clear evidence-based recommendations concerning when patients with prenatally diagnosed choledochal cysts (CCs) should undergo surgery. This study was primarily designed to explore the proper timing of minimally invasive surgery for prenatally diagnosed CC patients. METHODS: Seventy-three patients with prenatally diagnosed CC were enrolled in this study and divided into 4 subgroups according to age at surgery (15 patients in the < 1 month group, 27 in the 1-2 months group, 14 in the 2-3 months group and 17 in the > 3 months group)...
April 11, 2024: BMC Pediatrics
https://read.qxmd.com/read/38600453/predicting-chronological-age-of-14-or-18-in-adolescents-integrating-dental-assessments-with-machine-learning
#10
JOURNAL ARTICLE
Shihui Shen, Yibo Guo, Jiaxuan Han, Meizhi Sui, Zhuojun Zhou, Jiang Tao
AIM: Age estimation plays a critical role in personal identification, especially when determining compliance with the age of consent for adolescents. The age of consent refers to the minimum age at which an individual is legally considered capable of providing informed consent for sexual activities. The purpose of this study is to determine whether adolescents meet the age of 14 or 18 by using dental development combined with machine learning. METHODS: This study combines dental assessment and machine learning techniques to predict whether adolescents have reached the consent age of 14 or 18...
April 10, 2024: BMC Pediatrics
https://read.qxmd.com/read/38594697/resistance-training-presents-beneficial-effects-on-bone-development-of-adolescents-engaged-in-swimming-but-not-in-impact-sports-abcd-growth-study
#11
JOURNAL ARTICLE
Ricardo R Agostinete, André O Werneck, Pedro H Narciso, Esther Ubago-Guisado, Manuel J Coelho-E-Silva, Renata M Bielemann, Luis Alberto Gobbo, Bruna Turi Lynch, Romulo Araújo Fernandes, Dimitris Vlachopoulos
BACKGROUND: Sports practice during adolescence is important to enhance bone development, although it may provide different effects depending on the mechanical impact present in the sport. Besides, resistance training (RT) may also induce bone changes directly (via muscle contractions) and indirectly (via myokines). However, there have been no studies analyzing the longitudinal influence of engaging in sport with and without added mechanical load. Thus, this study aims to analyze the combined effects of sports participation and resistance training on areal bone mineral density (aBMD) accrual in adolescent athletes participating in swimming and impact sports for 12-months...
April 9, 2024: BMC Pediatrics
https://read.qxmd.com/read/38582899/chronic-stridor-in-a-toddler-after-ingestion-of-a-discharged-button-battery-a-case-report
#12
JOURNAL ARTICLE
Zoe S Oftring, Doortje M Mehrtens, Julian Mollin, Eckard Hamelmann, Sebastian Gaus
BACKGROUND: Button battery (BB) ingestions (BBI) are increasingly prevalent in children and constitute a significant, potentially life-threatening health hazard, and thus a pediatric emergency. Ingested BBs are usually charged and can cause severe symptom within 2 h. Discharged BBs ingestion is very rare and protracted symptom trajectories complicate diagnosis. Timely imaging is all the more important. Discharged BBs pose specific hazards, such as impaction, and necessitate additional interventions...
April 6, 2024: BMC Pediatrics
https://read.qxmd.com/read/38580989/epidermolysis-bullosa-two-rare-case-reports-of-col7a1-and-ebs-gen-sev-krt14-variants-with-review-of-literature
#13
REVIEW
Fatma Mabrouk Ali, Jieyu Zhou, Mingyan Wang, Qiuxia Wang, Lulu Sun, Mansour Maulid Mshenga, Hongyan Lu
EPIDERMOLYSIS: Bullosa is a rare hereditary skin condition that causes blisters. Genes encoding structural proteins at or near the dermal-epidermal junction are mutated recessively or dominantly, and this is the primary cause of EB. Herein, two Chinese boys were diagnosed with the condition, each with a different variant in a gene that serves as a reference for EB genetic counseling. Skincare significantly impacted their prognosis and quality of life. CASE PRESENTATION: Two Chinese boys, with phenotypically normal parents, have been diagnosed with distinct blister symptoms, one with Dominant Dystrophic Epidermolysis Bullosa and the other with a severe form of Epidermolysis Bullosa Simplex...
April 5, 2024: BMC Pediatrics
https://read.qxmd.com/read/38580968/cholangiocarcinoma-identified-in-perforated-choledochal-cyst-in-a-3-year-old-boy
#14
JOURNAL ARTICLE
Lun Yu, Wenli Xiu, Aimei Yue, Xiwei Hao, Zhong Jiang, Jie Wu, Qian Dong
Cholangiocarcinoma in patients with Choledochal cysts is rare in childhood; however, it seriously affects the prognosis of the disease. The key to addressing this situation lies in completely removing the extrahepatic cyst. We herein present a case report of a 3-year-old boy with cholangiocarcinoma associated with a choledochal cyst (CDC). Preoperative 3D simulation, based on CT data, played an important role in the treatment of this patient.
April 5, 2024: BMC Pediatrics
https://read.qxmd.com/read/38580952/growth-and-endocrinopathies-among-children-with-%C3%AE-thalassemia-major-treated-at-dubai-thalassemia-centre
#15
JOURNAL ARTICLE
Rabah Almahmoud, Amal Hussein, Fatheya Al Khaja, Ahmed Farrag Soliman, Hany Dewedar, Zainab Al Shareef, Sarah Mathai
BACKGROUND: β-Thalassemia major (BTM) is one of the most common hereditary anemias worldwide. Patients suffer from iron overload that results from repeated blood transfusion This in turn leads to multiple organ damage and endocrinopathies. This study aims to assess the prevalence of growth retardation, hypothyroidism, and diabetes mellitus in children and adolescents with BTM treated at Dubai Thalassemia Centre. METHODS: A total of 105 children and adolescents were included in this retrospective observational study...
April 5, 2024: BMC Pediatrics
https://read.qxmd.com/read/38580931/antibiotic-use-in-infants-at-risk-of-early-onset-sepsis-results-from-a-unicentric-retrospective-cohort-study
#16
JOURNAL ARTICLE
Catalina Morales-Betancourt, Diego Fontiveros-Escalona, Adriana Montealegre-Pomar, Tania Carbayo-Jiménez, María Palomares-Eraso, Concepción de Alba-Romero, Elena Bergón-Sendín, Maria Teresa Moral Pumarega, Carmen Pallás-Alonso
BACKGROUND: Antibiotic use for early-onset sepsis represents a high percentage of antibiotic consumption in the neonatal setting. Measures to assess infants at risk of early-onset sepsis are needed to optimize antibiotic use. Our primary objective was to assess the impact of a departmental guideline on antibiotic use among term infants with suspected EOS not confirmed, in our neonatal unit. METHODS: Retrospective cohort study, to compare antibiotic use in term infants during a baseline period of January to December 2018, and a postintervention period from October 2019, to September 2020, respectively...
April 5, 2024: BMC Pediatrics
https://read.qxmd.com/read/38575919/effect-of-play-based-intervention-on-children-s-mental-status-and-caregiver-involvement-during-hospitalization-findings-from-pakistan
#17
JOURNAL ARTICLE
Vardah Noor Ahmed Bharuchi, Muneera A Rasheed
BACKGROUND: The nurturing care framework (NCF) encompasses responsive caregiving, health, nutrition, safety and security by parents and other caregivers. It improves health, development and wellbeing of children. A hospital environment can be detrimental to the developmental and emotional needs of children hence NCF can be applied to hospitalized children. OBJECTIVE: The objective was to determine if (i) play stimulation intervention mediated by non-specialist providers (caregivers) improves mental status of children who are hospitalized; (ii) to examine if difference varies between different providers and iii) if there is variation based on child age and criticalness of illness...
April 4, 2024: BMC Pediatrics
https://read.qxmd.com/read/38575910/reconstitution-of-oral-antibiotic-suspensions-for-paediatric-use-in-households-a-cross-sectional-study-among-caregivers-of-3-5-year-old-children-from-a-selected-district-sri-lanka
#18
JOURNAL ARTICLE
Malith Kumarasinghe, Manuj C Weerasinghe
INTRODUCTION: Reconstitution of oral pediatric antibiotic suspension by primary caregivers plays an essential role in determining the overall health outcome of the child. Incorrect reconstitution techniques could lead to underdosing, overdosing, or introduction of infection. Underdosing could lead to non-resolving infection and antimicrobial resistance. OBJECTIVES: To assess the practice and associated factors on reconstitution of oral pediatric antibiotic suspensions (OPAS) among primary caregivers of 3-5-year-old children in a selected district in Sri Lanka...
April 4, 2024: BMC Pediatrics
https://read.qxmd.com/read/38575873/erythroferrone-and-hepcidin-levels-in-children-with-iron-deficiency-anemia
#19
JOURNAL ARTICLE
Ramazan Dulkadir, Gamze Turna Saltoğlu, Ali Güneş
BACKGROUND: Iron deficiency anemia remains a significant public health issue in developing countries. The regulation of iron metabolism is primarily controlled by hepcidin, a key regulatory protein. During erythropoiesis, erythroferrone (ERFE), a hormone produced by erythroblasts in response to erythropoietin (EPO) synthesis, mediates the suppression of hepcidin. In this study, it was aimed to determine the correlation between erythroferrone (ERFE) and hepcidin levels in children with iron deficiency anemia...
April 4, 2024: BMC Pediatrics
https://read.qxmd.com/read/38570804/clinical-characteristics-analysis-of-pediatric-spinal-cord-injury-without-radiological-abnormality-in-china-a-retrospective-study
#20
JOURNAL ARTICLE
Renfeng Liu, Qizhi Fan, Jingpeng He, Xin Wu, Wei Tan, Zuyun Yan, Weiguo Wang, Zhiyue Li, You-Wen Deng
PURPOSE: This study aims to analyze the clinical characteristics of Chinese children with spinal cord injury (SCI) without radiographic abnormality (SCIWORA) and explore their contributing factors and mechanisms of occurrence. METHODS: A retrospective analysis was conducted on the clinical data of pediatric patients diagnosed with SCIWORA from January 2005 to May 2020. Epidemiological, etiological, mechanistic, therapeutic, and outcome aspects were analyzed. RESULTS: A total of 47 patients with SCIWORA were included in this study, comprising 16 males and 31 females...
April 3, 2024: BMC Pediatrics
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