journal
https://read.qxmd.com/read/37770832/factors-affecting-the-benefit-of-glasses-alone-in-treating-childhood-amblyopia-an-analysis-of-pedig-data
#1
JOURNAL ARTICLE
Rosa T Hernández-Andrés, María Josefa Luque, Miguel-Ángel Serrano, Andrew Scally, Brendan T Barrett
BACKGROUND: To evaluate factors associated with better outcomes from optical treatment alone in amblyopic children from 3 up to 7 years. METHODS: Data extracted from two studies with similar protocols, Amblyopic Treatment Studies 5 (n = 152) and 13 (n = 128) from the Pediatric Eye Disease Investigator Group database, were used to determine by regression analysis the factors associated with improvements in visual acuity in the amblyopic eye, inter-ocular visual acuity difference and stereoacuity...
September 28, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37752499/unraveling-mucolipidosis-type-iii-gamma-through-whole-genome-sequencing-in-late-onset-retinitis-pigmentosa-a-case-report
#2
JOURNAL ARTICLE
Karl De Geer, Katarzyna Mascianica, Karin Naess, Eliane Sardh, Anna Lindstrand, Erik Björck
BACKGROUND: We describe the case of a 47-year-old man referred to a retinal clinic and diagnosed with late-onset retinitis pigmentosa. Surprisingly, genetic testing revealed compound heterozygous pathogenic variants in GNPTG, leading to the diagnosis of the autosomal recessive lysosomal storage disorder mucolipidosis type III gamma. Mucolipidosis type III gamma is typically diagnosed during childhood due to symptoms relating to skeletal dysplasia. Retinal dystrophy is not a common phenotypic feature...
September 26, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37752489/a-novel-microdeletion-of-517%C3%A2-kb-downstream-of-the-pax6-gene-in-a-chinese-family-with-congenital-aniridia
#3
JOURNAL ARTICLE
Yinwen Li, Jieqiong Chen, Ying Zheng, Zhixuan Chen, Tao Wang, Qian Sun, Xiaoling Wan, Haiyun Liu, Xiaodong Sun
BACKGROUND: To identify the disease-causing gene in a Chinese family affected with congenital aniridia. METHODS: Patients underwent systematic ophthalmic examinations such as anterior segment photography, fundus photography, optical coherence tomography, and fundus fluorescein angiography. The proband was screened for pathogenic variants by whole exome sequencing (WES) and copy number variant (CNV) analysis. Real-time quantitative PCR (RT-qPCR) was applied to confirm the CNV results...
September 26, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37752483/spontaneous-regression-of-an-isolated-retinal-astrocytic-hamartoma-in-a-newborn-a-case-report
#4
JOURNAL ARTICLE
Bo Yang, Danfeng Li, Jun Xiao
BACKGROUND: To report the spontaneous regression of an isolated retinal astrocytic hamartoma in a newborn. During the seven-month follow-up duration, fundus photography and fluorescein angiography examinations were performed. CASE PRESENTATION: An isolated retinal astrocytic hamartoma was detected in the nasal retina of the left eye of a 4-day-old male infant. At the time of initial presentation, we detected a solitary yellowish-white flat mass with an approximate size of 1...
September 26, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37752479/four-flanged-polypropylene-optic-piercing-technique-for-scleral-fixation-of-multifocal-intraocular-lens
#5
JOURNAL ARTICLE
Youngsub Eom, Eunheh Koh, Seul Ki Yang, Soo Kim, Sungtae Yi, Hyun Sun Jeon, Seong-Jae Kim, Jason So, Jong Suk Song, David L Cooke
BACKGROUND: To evaluate the feasibility of creating flanges using an optic piercing technique with a 6 - 0 polypropylene monofilament for scleral fixation of dislocated one-piece diffractive multifocal intraocular lenses (IOLs). STUDY DESIGN: Experimental study and case series. SUBJECTS: Optical bench test and eyes with IOL dislocation. METHODS: Two separate 6 - 0 polypropylenes were penetrated twice at the opposite peripheral optic of the TECNIS Synergy IOL (Johnson & Johnson Vision)...
September 26, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37752465/a-unique-case-of-bilateral-nanophthalmos-and-pigmentary-retinal-abnormality-with-unilateral-angle-closure-glaucoma-and-optic-disc-pit
#6
JOURNAL ARTICLE
Prerna Garg, Brajesh Kumar, Suneeta Dubey
BACKGROUND: Microophthalmos or 'dwarf eye' is characterized by an axial length 2 standard deviation less than age-matched controls. It is classified into nanophthalmos, relative anterior microphthalmos, and posterior microphthalmos based on the anterior segment: posterior segment ratio. Nanophthalmos can occur in association with optic disc drusen, foveoschisis, and retinitis pigmentosa, as an autosomal recessive syndrome linked to mutations in the MFRP gene. We report a case of bilateral nanophthalmos and pigmentary retinopathy with angle closure glaucoma and optic disc pit in one eye...
September 26, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37752463/prevalence-of-human-papillomavirus-in-eyelid-carcinoma-among-koreans-a-clinicopathological-study
#7
JOURNAL ARTICLE
Min Kyu Yang, Namju Kim, Hokyung Choung, Ji Eun Kim, Sang In Khwarg
BACKGROUND: Human papillomavirus (HPV) has been detected in eyelid sebaceous gland carcinoma (SGC) and squamous cell carcinoma (SCC), and detection rates greatly varied across studies. This study aimed to investigate the presence of HPV in eyelid SGC and SCC among Koreans and its correlation with clinicopathological characteristics. METHODS: Surgically resected eyelid samples diagnosed as SGC or SCC from January 1999 to June 2011 were identified from the pathology database of three referral centres in Korea...
September 26, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37752454/stellate-nonheritable-idiopathic-foveomacular-retinoschisis-in-juveniles-case-report
#8
JOURNAL ARTICLE
Jianan Liu, Yanhui Wang, Lifei Wang
BACKGROUND: Stellate nonhereditary idiopathic foveomacular retinoschisis (SNIFR) is a rare type of retinoschisis with a spoke-like splitting that occurs in the outer plexus layer. We present a case of stellate nonhereditary idiopathic foveomacular retinoschisis in a juvenile, in which two eyes show different development trends and macular retinoschisis could be associated with mechanical force in the Henle fibre layer. The removal of mechanical force can partially restore vision. CASE PRESENTATION: A 14-year-old girl with bilateral SNIFR was diagnosed and followed up with spectral-domain optical coherence tomography (SD-OCT)...
September 26, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37743488/fil-ssf-intraocular-lens-opacification-after-pars-plana-vitrectomy-with-gas-tamponade-for-traumatic-lens-luxation-and-retinal-detachment-a-case-report-and-literature-review
#9
JOURNAL ARTICLE
Danilo Iannetta, S Febbraro, N Valsecchi, A Moramarco, L Fontana
BACKGROUND: To report a case of sutureless scleral-fixated hydrophilic intraocular lens (FIL SSF IOL, Soleko, Italy) opacification following pars plana vitrectomy surgery using sulfur hexafluoride (SF6) for traumatic lens luxation associated with retinal detachment. CASE PRESENTATION: A 77-year-old woman was referred to our emergency department after blunt trauma in her right eye. At the ophthalmic evaluation, visual acuity was hand movement, biomicroscopy showed pseudoexfoliation syndrome and a traumatic lens luxation in the vitreous chamber...
September 25, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37740201/identification-of-potential-biomarkers-of-myopia-based-on-machine-learning-algorithms
#10
JOURNAL ARTICLE
Shengnan Zhang, Tao Wang, Huaihua Wang, Bingfang Gao, Chao Sun
PURPOSE: This study aims to identify potential myopia biomarkers using machine learning algorithms, enhancing myopia diagnosis and prognosis prediction. METHODS: GSE112155 and GSE15163 datasets from the GEO database were analyzed. We used "limma" for differential expression analysis and "GO plot" and "clusterProfiler" for functional and pathway enrichment analyses. The LASSO and SVM-RFE algorithms were employed to screen myopia-related biomarkers, followed by ROC curve analysis for diagnostic performance evaluation...
September 22, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37735637/clinical-features-of-retinopathy-after-cardiopulmonary-resuscitation
#11
JOURNAL ARTICLE
Su Hwan Park, Sang Yoon Kim, Sung Who Park, Iksoo Byon, Seung Min Lee
PURPOSE: To evaluate the clinical patterns of retinopathy in patients who received cardiopulmonary resuscitation (CPR) using wide-field fundus photography and slit-lamp fundus examination. METHODS: The medical records of patients aged ≥ 18 years who survived after receiving CPR and underwent wide-field fundus photography and slit-lamp fundus examination within 3 months were retrospectively analyzed. Fundus findings, including retinal hemorrhage and cotton wool spots, were investigated...
September 21, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37735358/freeze-dried-amniotic-membrane-graft-with-a-spongy-layer-in-bilateral-peripheral-ulcerative-keratitis-a-case-report
#12
JOURNAL ARTICLE
Clara Bertret, Loïc Leveziel, Juliette Knoeri, Cristina Georgeon, Céline Jamart, Nacim Bouheraoua, Vincent Borderie
BACKGROUND: Peripheral ulcerative keratitis (PUK) is a group of inflammatory corneal ulcers with stromal thinning and peripheral localization. Amniotic membranes (AM) are used for their anti-inflammatory and healing properties. A freeze-drying process now allows maintaining the AM viable for a long time at room temperature without altering its physical, biological, and morphologic characteristics. The effectiveness of spongy freeze-dried amniotic membrane (FD-AM) graft with multimodal imaging in the management of severe corneal thinning PUK has not been reported...
September 21, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37726720/treatment-strategy-for-bvo-me-based-on-long-term-outcomes-correlating-retinal-structure-by-oct-image-and-visual-acuity
#13
JOURNAL ARTICLE
Yuki Hattori, Ryo Fujiwara, Hidetsugu Mori, Motoki Kimura, Haruhiko Yamada, Kanji Takahashi
BACKGROUND: Intravitreal anti-vascular endothelial growth factor (VEGF) is a mainstream treatment for reducing ME secondary to BRVO (BVO-ME). Regrettably, most reports of intravitreal anti-VEGF for BVO-ME have disclosed only short-term outcomes. Here, we characterized long-term indicators for the visual prognosis of patients with BVO-ME, including the correlation between retinal structure by OCT and visual acuity. METHODS: Patients with BVO-ME were retrospectively recruited based on clinical records in Kansai Medical University Hospital from June 2012 to March 2022...
September 20, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37726746/alterations-in-choroidal-circulatory-dynamics-and-choroidal-thickness-before-and-after-treatment-in-posterior-scleritis
#14
JOURNAL ARTICLE
Mizuho Mitamura, Satoru Kase, Yui Yamashita, Kiriko Hirooka, Susumu Ishida
BACKGROUND: Posterior scleritis is an inflammatory reaction of the sclera that occurs posterior to the ora serrata. The aim of this study was to present a case of posterior scleritis and to analyze choroidal circulatory and structural changes using laser speckle flowgraphy (LSFG) and optical coherence tomography (OCT), respectively. CASE PRESENTATION: A 64-year-old man presented to our department because of hyperemia of the left eye for one week, diplopia, ocular pain, and distorted vision when looking leftward...
September 19, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37726700/topical-injection-of-sclerosant-to-treat-cheek-subcutaneous-venous-malformation-resulting-in-blindness-a-case-report
#15
JOURNAL ARTICLE
Lihong Cui, Xinyue Zhang, Li Xu
Loss of vision after topical injection of sclerosant is a rare and uncommon complication. We describe a case with vision loss following the facial injections of physician-compounded (PCP) foam sclerotherapy which was created by room air. A 3-year-old boy underwent injection of 5ml polidocanol foamed with room air to treat the venous malformation on the cheek near the left orbit. The boy experienced the whole facial swelling on day 2 after the third injection, especially involving the left side, the visual acuity in the left eye was counting fingers at 30 cm and the swelling reduced at 7 days later after referral...
September 19, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37723524/choroid-vascular-changes-in-hyperopic-anisometropia-amblyopia-using-ss-octa
#16
JOURNAL ARTICLE
Yiwen Cao, Yadi Zhang, Xiaopeng Gu, Dehai Zhu, Liu Yang
PURPOSE: To observe and understand the structural changes in choroidal vessels in eyes with hyperopic anisometropic amblyopia using swept-source optical coherence tomography angiography (SS-OCTA). METHODS: A total of 44 patients were enrolled in this study: 22 children with hyperopic anisometropic amblyopia and 22 age-matched controls. SS-OCTA was used to scan the 6*6 mm macular area of their eyes. The average choroidal thickness (CT) and choroidal capillary flow area (CC) in a 3 mm diameter area centered on the macular area were obtained...
September 18, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37723468/comprehensive-evaluation-of-functional-vision-quality-of-life-and-cognitive-ability-in-pediatric-uveitis
#17
JOURNAL ARTICLE
Wenjuan Wan, Zhijun Chen, Yan Xun, Kun Yi, Ying Zhu, Yanlin Pu, Guannan Su, Chunjiang Zhou, Yao Wang, Peizeng Yang
BACKGROUND: Pediatric uveitis may cause severe impairment of vision in children and affect their quality of life as well as cognitive ability. This study aims to evaluate the functional vision, visual-related and health-related quality of life, and cognitive ability in pediatric uveitis. METHODS: Children with uveitis aged 5-16 years old completed six validated instruments to assess functional visual ability with Cardiff Visual Ability Questionnaire for Children (CVAQC), vision-related quality of life with Impact of Vision Impairment for Children (IVI-C), health-related quality of life with Pediatric Quality of Life Inventory (PedsQL), cognitive ability with Chinese Wechsler Intelligence Scale for Children (C-WISC), and depression and anxiety evaluation with Hospital Anxiety and Depression Scale (HAD)...
September 18, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37723463/real-world-treatment-patterns-and-economic-burden-of-post-cataract-macular-edema
#18
JOURNAL ARTICLE
Gina Ahmadyar, Josh J Carlson, Alan Kimura, Ali Alobaidi, Joelle Hallak, Ryan N Hansen
BACKGROUND: Post-cataract macular edema (PCME) is a condition that can occur in patients following cataract surgery without risk factors and complications. Although 80% of patients experience spontaneous resolution after 3 to 12 months, in persistent cases, it can lead to permanent vision loss if left untreated. There are currently no standardized treatment guidelines for PCME, and there have been limited studies showing the impact of PCME on annual Medicare spending and ophthalmology-related outpatient visits per case compared to those without the complication...
September 18, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37710225/characteristics-of-brittle-cornea-syndrome-by-multimodal-imaging-modalities-a-case-report
#19
JOURNAL ARTICLE
Huixian Wang, Xu Zhang, Xiaowei Gao, Wenjing Li
BACKGROUND: A report of a Brittle cornea syndrome (BCS) case with bluish scleral discoloration, keratoglobus, and myopia based on multimodal imaging modalities including in vivo confocal microscopy (IVCM), high-definition optical coherence tomography (HD-OCT) and scheimpflug corneal densitometry analysis. CASE PRESENTATION: A 36-year-old Chinese female patient presented with significant bluish discoloration of the sclera in both eyes, extreme corneal thinning with increased corneal curvature, increased central corneal densitometry, and nystagmus...
September 15, 2023: BMC Ophthalmology
https://read.qxmd.com/read/37710237/endoscopy-assisted-pars-plana-vitrectomy-in-retinal-detachments-associated-with-anterior-proliferative-vitreoretinopathy-and-epiciliary-membranes
#20
JOURNAL ARTICLE
Radwan S Ajlan, Matthew Pfannenstiel, Yong Kam, Harrison Sciulli
BACKGROUND: Proliferative vitreoretinopathy (PVR) is the leading cause of recurrent retinal detachment. Anterior PVR can contribute to recurrent retinal detachment and is often difficult to remove during conventional pars plana vitrectomy. The purpose of this study is to report surgical outcomes of single endoscopy-assisted pars plana vitrectomy (E-PPV) in patients with tractional retinal detachments associated with anterior proliferative vitreoretinopathy and epiciliary membranes. METHODS: Retrospective review of E-PPV between 2017 and 2021 at a tertiary referral center...
September 14, 2023: BMC Ophthalmology
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