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Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft

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https://read.qxmd.com/read/30753896/a-novel-intraoral-injection-technique-for-rat-levator-veli-palatini-muscle-regeneration
#1
Xu Cheng, Hanyao Huang, Bing Shi, Jingtao Li
BACKGROUND: The levator veli palatini (LVP) muscle drives the elevation and retraction of the soft palate to facilitate speech and feeding, but undergoes atrophic changes in patients with cleft palate deformity. This study aimed to establish an effective drug delivery technique for LVP muscle regeneration. METHODS: An intraoral injection technique for rat LVP muscle regeneration was developed based on careful examination of the rat craniofacial anatomy. The accuracy and reliability of this technique were tested by cone-beam computed tomography and nitrocellulose dye labeling...
February 9, 2019: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30738175/comparative-morphology-of-the-primate-tongue
#2
REVIEW
Shin-Ichi Iwasaki, Ken Yoshimura, Junji Shindo, Ikuo Kageyama
To clarify the role of the primate tongue as a means to better understand the evolution of oral function among primates - an example of adaptation within the restricted phylogenetic group - we review the morphological knowledge of the tongues of extant primates in relation to phylogenetic classification. Prosimians tongues are more effective than those of Haplorhini for taking up food with the tongue alone, because they are capable of fine movement when outside the oral cavity. However, the role of the tongue in food uptake has diminished when juxtaposed with progress in hand manipulation of food and tools in Haplorhini, especially with the manipulation of tools by Homininae...
February 6, 2019: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30731200/radiologist-s-views-on-anatomical-knowledge-amongst-junior-doctors-and-the-teaching-of-anatomy-in-medical-curricula
#3
Gerard W O'Keeffe, Shane Davy, Denis S Barry
Reduced teaching resources, increasing student numbers and congested medical curricula have reportedly led to reports of inadequate anatomical knowledge among newly qualified doctors, placing scrutiny on pre-clinical education. We wished to gauge the opinions of practicing radiologists on undergraduate anatomy education. Members of the Irish Faculty of Radiologists were invited to complete a questionnaire based on undergraduate anatomical education. Out of 67 respondents, 69% were of senior grade, with the majority working in aspects of diagnostic radiology...
February 4, 2019: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30731199/the-history-of-anatomical-research-of-lymphatics-from-the-ancient-times-to-the-end-of-the-european-renaissance
#4
REVIEW
Regina Irschick, Claudia Siemon, Erich Brenner
Very often, descriptions of the scientific discovery of the lymphatic system start with Gaspare Aselli, probably because of his so captivating account. Nevertheless, there was prior and even very old evidence of the lymphatic vessels, which was of course known to Aselli himself, as he cited most of these antique references. In fact, the first insights were contributed by the Hippocratic School. The Alexandrian School added quite a lot but unfortunately most of that knowledge isn't extant and can only be appreciated by translations or citations by other authors such as Galen...
February 4, 2019: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30721719/glp-1-mediated-improvement-of-the-glucose-tolerance-in-the-t2dm-gk-rat-model-after-massive-jejunal-resection
#5
J Arturo Prada-Oliveira, Alonso Camacho-Ramírez, Jesús Salas-Alvarez, Francisco Javier Campos-Martínez, Alfonso M Lechuga-Sancho, David Almorza-Gomar, Manuel Blandino-Rosano, Gonzalo M Pérez-Arana
OBJECTIVE: The aim of this study was to clarify the role of the middle gut in the entero-pancreatic axis modification that leads to glucose improvement in the Goto-Kakizaki (GK) rat as a non-obese T2DM model. BACKGROUND: Bariatric surgery is considered an assured solution for type 2 Diabetes (T2DM). Enterohormones such as ghrelin, gastric inhibitory polypeptide and mainly glucagon-like peptide-1 (GLP-1) were recognized as key players in the physiophathological mechanisms associated with entero-pancreatic axis regulation and glucose tolerance improvement...
February 2, 2019: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30716468/localization-of-nitro-tyrosine-immunoreactivity-in-human-retina
#6
Tapas C Nag, Poorti Kathpalia, Shilpa Gorla, Shashi Wadhwa
Oxidative stress (OS) is associated with retinal aging and age-related macular degeneration (AMD).In both cases there are reports for the presence of markers of lipid peroxidation in retinal cells. We investigated if nitrosative stress also occurs in the human retina with aging. We examined the cellular localization of nitro-tyrosine, a biomarker of protein tyrosine nitration, in human donor retina (17-91 years; N = 15) by immunohistochemistry. Immunoreactivity (IR) to nitro-tyrosine was present in ten retinas and absent in five retinas...
February 1, 2019: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30716467/altered-laryngeal-morphology-in-period1-deficient-mice
#7
Olaf Bahlmann, Christoph Schürmann, Erik Marond
BACKGROUND: Ultrasonic vocalizations (USV) of mice are produced in and emitted by the larynx. However, which anatomical elements of the mouse larynx are involved and to which aspects of USV they contribute is not clear. Frequency and amplitude parameters of mice, deficient in the clock gene Period1 (mPer1-/- mice) are distinguishably different compared to C3H wildtype (WT) controls. Because structural differences in the larynx may be a reason for the different USV observed, we analyzed laryngeal anatomy of mPer1-/- mice and WT control animals using micro-computer-tomography and stereology...
February 1, 2019: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30716466/deep-lymphatic-anatomy-of-the-upper-limb-an-anatomical-study-and-clinical-implications
#8
Chuan-Xiang Ma, Wei-Ren Pan, Zhi-An Liu, Fan-Qiang Zeng, Zhi-Qiang Qiu, Mei-Ying Liu
BACKGROUND: The deep and perforating lymphatic anatomy of the upper limb still remains the least described in medical literature. MATERIALS AND METHODS: Six upper limbs with the axillary tissue were harvested from three unembalmed human cadavers amputated at the shoulder joint. A small amount of 6% hydrogen peroxide was employed to detect the lymphatic vessels around the deep palmar arch, radial and ulnar neurovascular bundles. A 30-gauge needle was inserted into the vessels and they were injected with a barium sulphate compound...
February 1, 2019: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30599239/numerical-investigations-of-bone-remodelling-around-the-mouse-mandibular-molar-primordia
#9
Junliang Chen, Yun He, Ludger Keilig, Susanne Reimann, Istabrak Hasan, Joachim Weinhold, Ralf Radlanski, Christoph Bourauel
The formation of the alveolar bone, which houses the dental primordia, and later the roots of tooth, may serve as a model to approach general questions of alveolar bone formation. In this respect, this study aimed to investigate the potential interactions between the alveolar bone formation and tooth eruption by using finite element (FE) methods, and to figure out whether the expanding tooth systems induce shear stresses that lead to alveolar bone formation. 3D geometric surface models were generated from the 3D histological data of the heads of mice (C57 Bl/6J) ranging from stages embryonic (E) to postnatal (P) stages E15 to P20 using the reconstruction software 3-Matic...
December 29, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30599238/anatomic-conditions-for-bypass-surgery-between-rostral-t7-t9-and-caudal-l2-l4-s1-ventral-roots-to-treat-paralysis-after-spinal-cord-injury
#10
Habib Bendella, Rink Svenja, Aliona Wöhler, Janna Feiser, Andre Wilden, Maria Grosheva, Hans-Jürgen Stoffels, Carolin Meyer, Marilena Manthou, Makoto Nakamura, Doychin N Angelov
Severe spinal cord injuries cause permanent neurological deficits and are still considered as inaccessible to efficient therapy. Injured spinal cord axons are unable to spontaneously regenerate. Re-establishing functional activity especially in the lower limbs by reinnervation of the caudal infra-lesional territories might represent an effective therapeutic strategy. Numerous surgical neurotizations have been developed to bridge the spinal cord lesion site and connect the intact supra-lesional portions of the spinal cord to peripheral nerves (spinal nerves, intercostal nerves) and muscles...
December 29, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30594647/updates-in-the-fields-of-dental-anatomy-implantology-and-bone-regeneration
#11
EDITORIAL
Christiane Kunert-Keil, Ines Zeidler-Rentzsch, Werner Götz, Friedhelm Heinemann
No abstract text is available yet for this article.
December 27, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30590121/carthamus-tinctorius-l-extract-attenuates-cardiac-remodeling-in-l-name-induced-hypertensive-rats-by-inhibiting-the-nadph-oxidase-mediated-tgf-b1-and-mmp-9-pathway
#12
Sarawoot Bunbupha, Poungrat Pakdeechote, Putcharawipa Maneesai, Parichat Prachaney, Pattanapong Boonprom
Carthamus tinctorius L. (CT) has been widely used in Asian countries as a beverage and a folk medicine. The current study investigates the effect of CT extract on cardiac remodeling and possible mechanisms involved in Nw -nitro-L-arginine methyl ester hydrochloride (L-NAME)-induced hypertensive rats. Male Sprague-Dawley rats were administrated with L-NAME (40mg/kg/day) for five weeks to induce hypertension. Hypertensive rats were treated with CT extract (300mg/kg/day) or captopril (5mg/kg/day) or vehicle for a further two weeks...
December 24, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30586608/leveraging-medical-imaging-for-medical-education-a-cinematic-rendering-featured-lecture
#13
Johannes Binder, Christian Krautz, Klaus Engel, Franz A Fellner, Pascal H M Burger, Michael Scholz
BACKGROUND: The integration of medical imaging into anatomical education offers advantages in understanding and learning. However, spatial orientation with conventional (2D) imaging data is challenging, and the students' ability to imagine structures in three dimensions is individual. In addition, the quality of current volume rendering methods is limited. OBJECTIVE: We tested Cinematic Rendering (CR), a novel visualization technique that provides photorealistic volume rendering, in the setting of an interactive anatomy lecture with first-year undergraduate medical and dental students...
December 23, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30580056/in-vitro-effects-of-benzalkonium-chloride-and-prostaglandins-on-human-meibomian-gland-epithelial-cells
#14
Anca Rath, Michael Eichhorn, Katharina Träger, Friedrich Paulsen, Ulrike Hampel
PURPOSE: Benzalkonium chloride is the most widely used preservative in ophthalmic topical solutions. The aim of this study was to investigate the influence of BAC as a single substance or as a component of several commercially available ophthalmic solutions on meibomian gland epithelial cells in vitro. MATERIALS AND METHODS: An immortalized human meibomian gland epithelial cell line (HMGEC) was used and cells were cultured in the absence or presence of fetal bovine serum to assess cell morphology, cell proliferation, cell viability (MTS assay) and impedance sensing (ECIS) after stimulation with BAC...
December 20, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30580055/organ-regeneration-evolved-in-fish-and-amphibians-in-relation-to-metamorphosis-speculations-on-a-post-embryonic-developmental-process-lost-in-amniotes-after-the-water-to-land-transition
#15
REVIEW
Lorenzo Alibardi
Organ regeneration occurs in anamniotes (fish and amphibians) while is absent in amniotes (reptiles, birds and mammals). An evolutionary hypothesis is presented to explain the loss of organ regeneration in amniotes. The aquatic life in fish or the initial aquatic and later terrestrial life in amphibians requires complex life cycles after embryonic development. One or more larval stages that occupy different ecological niches are necessary in fish to reach the final adult stage, generally through metamorphosis...
December 20, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30580054/the-effect-of-consecutive-pregnancies-on-the-ovine-pelvic-soft-tissues-link-between-biomechanical-and-histological-components
#16
Rita Rynkevic, Pedro Martins, Marco Parente, Teresa Mascarenhas, Henrique Almeida, Antonio A Fernandes
BACKGROUND: Pelvic organ prolapse, various types of incontinence (urinary incontinence, defecatory dysfunction), chronic cystourethritis, and sexual dysfunctions remain the most common disorders in urogynecology. Currently, it is believed that the nature and number of births plays a major role in their development. Moreover, after these events, pelvic floor tissues may not recover to their original statuses. The close anatomical relationship among the vaginal wall, bladder and rectum often contribute to the emergence of anatomical-functional failure of adjacent organs and systems...
December 20, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30566896/histological-comparison-between-laser-microtome-sections-and-ground-specimens-of-implant-containing-tissues
#17
Christiane Kunert-Keil, Heiko Richter, Ines Zeidler-Rentzsch, Isabel Bleeker, Tomasz Gredes
Evaluation of bone regeneration and peri-implant bone apposition can only be accomplished using laboratory techniques that allow assessment of decalcified hard tissue. It is known that 5-15μm thick sections can be prepared with the cutting-grinding technique, but their production causes a high material loss (≥0.5mm) between two sections and requires years of training and experience. With the development of the laser microtome it has become possible to cut decalcified bone without high sample material loss...
December 16, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30566895/ontogeny-of-calcium-binding-proteins-in-the-cingulate-cortex-of-the-guinea-pig-the-same-onset-but-different-developmental-patterns
#18
Beata Hermanowicz-Sobieraj, Krystyna Bogus-Nowakowska, Maciej Równiak, Anna Robak
This paper compared the density of calbindin D28k (CB), calretinin (CR) and parvalbumin (PV) containing neurons in prenatal, newborn and postnatal periods in the cingulate cortex (CC) of the guinea pig as an animal model. The distribution and co-distribution among calcium-binding proteins (CaBPs) was also investigated during the entire ontogeny. The study found that CB-positive neurons exhibited the highest density in the developing CC. The CC development in the prenatal period took place with a high level of CB and CR immunoreactivity and both of these proteins reached peak density during fetal life...
December 16, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30529571/desmogleins-as-signaling-hubs-regulating-cell-cohesion-and-tissue-organ-function-in-skin-and-heart-efem-lecture-2018
#19
Jens Waschke
Cell-Cell contacts are crucial for intercellular cohesion and formation of endothelial and epithelial barriers. Desmosomes are the adhesive contacts providing mechanical strength to epithelial intercellular adhesion and therefore are most abundant in tissues subjected to high mechanical stress such as the epidermis and heart muscle. Desmogleins (Dsg) besides intercellular adhesion serve as signalling hubs regulating cell behaviour. In desmosomal diseases such as the autoimmune blistering skin disease pemphigus or arrhythmic cardiomyopathy (AC), which is caused by mutations of desmosomal components of cardiomyocyte intercalated discs, the adhesive and signalling functions of desmosomes are impaired...
December 7, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://read.qxmd.com/read/30521949/beneficial-effect-of-curcumin-nanoparticles-hydrogel-on-excisional-skin-wound-healing-in-type-i-diabetic-rat-histological-and-immunohistochemical-studies
#20
Samaa Samir Kamar, Dina Helmy Abdel-Kader, Laila Ahmed Rashed
Management of diabetic wounds remains a major challenge in the medical field, mostly due to incompetent outcomes of treatments. Curcumin has been documented as anti-inflammatory, antioxidant, antimicrobial and antineoplastic agent in addition to wound healing activities. However, its poor aqueous solubility and impaired skin permeation handicap its topical pharmaceutical usage. Hydrogel loaded curcumin nanoparticle (Cur-NP/HG) could overcome this pitfall and enable extended topical delivery of curcumin. Rat model of diabetes mellitus (DM) type I was induced using single injection of 70mg/kg streptozotocin (STZ) followed by full thickness skin wound...
December 3, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
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