Iglesias-Velazquez Oscar, G F Tresguerres Francisco, F Tresguerres Isabel, Leco-Berrocal Isabel, Lopez-Pintor Rosa, Baca Laura, Torres Jesus
The knowledge of bone biology has undergone major advances in recent decades. In bone, resorbing osteoclasts have classically been described as tissue-resident macrophages, however, it is currently known that a new subtype of macrophages, called OsteoMacs, are specialised bone-resident macrophages, which, depending on certain conditions, may play an important role not only in bone homeostasis, but also in promoting pro-anabolic functions or in creating an inflammatory environment. There is growing evidence that these osteal macrophages may influence the development of bone-loss diseases...
March 14, 2024: Annals of Anatomy