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Heart, Lung & Circulation

Lara Rimmer, Mohammad U Ahmad, Grace Chaplin, Mihika Joshi, Amer Harky
The advent of aortic valve repair alongside the well-established technique of valve replacement changed the landscape of cardiac surgery, as well as the lives of patients suffering from valvular disease. Repair represents a novel option in those unfit for replacement and avoids the burden of lifelong anticoagulation in younger patients. Despite this, the associated risk of persistence of aortic insufficiency, and therefore reoperation, with valvular repair renders clinical decision making between the two techniques difficult...
March 4, 2019: Heart, Lung & Circulation
Vinesh Appadurai, Michael T Burke, Alex Frampton, Mugur Nicolae
No abstract text is available yet for this article.
February 26, 2019: Heart, Lung & Circulation
Benjamin M Moore, Kim H Chan, Raymond W Sy
No abstract text is available yet for this article.
February 25, 2019: Heart, Lung & Circulation
Bishwo Shrestha, Sylvia Shrestha, Paul Peters, Masashi Ura, Morgan Windsor, Rishendran Naidoo
BACKGROUND: Catamenial pneumothorax (CP) is an unusual condition affecting premenopausal women and commonly misdiagnosed as simple pneumothorax. It is characterised by its recurrence between the day before and within 72 hours after the onset of menstruation. It has been associated with thoracic endometriosis but the aetiology is not well understood and there is no unified agreement for its optimal management. The aim of this study is to determine the incidence of CP in surgical patients and the results of their treatment...
February 22, 2019: Heart, Lung & Circulation
An Tran-Duy, Robyn McDermott, Josh Knight, Xinyang Hua, Elizabeth L M Barr, Kerry Arabena, Andrew Palmer, Philip M Clarke
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death for Indigenous Australians. There is widespread belief that current tools have deficiencies for assessing CVD risk in this high-risk population. We sought to develop a 5-year CVD risk score using a wide range of known risk factors to further improve CVD risk prediction in this population. METHODS: We used clinical and demographic information on Indigenous people aged between 30 and 74 years without a history of CVD events who participated in the Well Person's Health Check (WPHC), a community-based survey...
February 22, 2019: Heart, Lung & Circulation
Hiu L Ip, Samuel Menahem
BACKGROUND: Innocent murmurs are common in childhood. Echocardiography may diagnose almost all congenital cardiac abnormalities. Earlier studies have suggested that it may be unnecessary when a clinical diagnosis of an innocent murmur is made by an experienced cardiologist. Yet, echocardiography is commonly performed despite such a diagnosis. Is that justifiable? METHODS: Patients referred to a paediatric cardiologist for evaluation of a murmur were assessed. If an innocent murmur was clinically diagnosed, an echocardiogram and an electrocardiogram were ordered when requested...
February 16, 2019: Heart, Lung & Circulation
Richard E Jones, Katherine M Groom, Arvind Singh, Hugo Lai, Jason N Dungu, Filomena Medeiros, Aroon Lal, Rossella M Barbagallo
No abstract text is available yet for this article.
February 15, 2019: Heart, Lung & Circulation
Ellie Paige, Jason Agostino, Christine Phillips, Julian Elliott, Dominique A Cadilhac, Cia Connell, Melanie Kowalski, Lily O'Donoughue Jenkins, Amanda Daluwatta, Emily Banks
No abstract text is available yet for this article.
February 11, 2019: Heart, Lung & Circulation
Thomas H Marwick
No abstract text is available yet for this article.
February 11, 2019: Heart, Lung & Circulation
Kazuhiro Kuroda, Satoshi Akagi, Kazufumi Nakamura, Toshihiro Sarashina, Kentaro Ejiri, Hiroshi Ito
BACKGROUND: Transition to pulmonary arterial hypertension (PAH)-specific drugs is considered in patients with PAH and chronic thromboembolic pulmonary hypertension who do not respond to combination therapy or who experience side effects to the combination drugs. Riociguat directly stimulates soluble guanylate cyclase independently of nitric oxide. Therefore, transition from a phosphodiesterase type 5 inhibitor (PDE5i), which requires nitric oxide to exert its effects, to riociguat might be effective...
February 7, 2019: Heart, Lung & Circulation
Vimalraj Bogana Shanmugam, Peter J Psaltis, Leslie Tay, Yuvaraj Malaiapan, Wally Ahmar
BACKGROUND: Bifurcation percutaneous coronary intervention (PCI) remains a challenging frontier in interventional cardiology, especially in the setting of ST-elevation myocardial infarction (STEMI). We examined the procedural and clinical outcomes of this patient subset. METHODS: We conducted a retrospective case-control study. Between February 2006 and March 2011, 129 patients with STEMI underwent bifurcation PCI at our institution. One hundred and twenty-nine (129) control STEMI patients with non-bifurcation PCI were selected from the institutional database, matched for age, gender, culprit vessel, and lesion location...
February 6, 2019: Heart, Lung & Circulation
David H Tian, Ashley Wilson-Smith, Shanq Kuen Koo, Paul Forrest, Hosen Kiat, Tristan D Yan
BACKGROUND: Antegrade cerebral perfusion (ACP) is an essential adjunct for prolonged hypothermic circulatory arrest (HCA) during aortic arch surgery. However, it has yet to be established whether ACP should be delivered unilaterally or bilaterally. The aim of the present meta-analysis is to investigate outcomes of unilateral ACP (uACP) compared to bilateral ACP (bACP) in comparative studies. METHODS: Electronic searches were performed using four databases from their inception to February 2017...
February 3, 2019: Heart, Lung & Circulation
Monira Sharif, Chris Ho Ming Wong, Amer Harky
Sternal wound infection (SWI) is one of the potential complications post cardiac surgery, and despite refined surgical techniques such as smaller incisions, antibiotic therapy, and optimised glycaemic control, the incidence rate is between <1% in elective cases with low risk factors and as high as 25% in patients with extensive risk factors. The presence of SWI will increase the perioperative morbidity and mortality rates and prolong the patient's hospital stay, therefore the prevention and diagnosis with appropriate management of such adverse outcomes at an early stage is important to prevent further progression as it can be fatal when the mediastinal structures are affected...
February 2, 2019: Heart, Lung & Circulation
Juliana van der Merwe, Eldho Paul, Franklin L Rosenfeldt
BACKGROUND: Measurements of organ flow and perfusion during cardiopulmonary bypass suggest that perfusion of the splanchnic bed can be impaired by non-pulsatile flow. We postulated that non-pulsatile flow from centrifugal ventricular assist devices might also compromise splanchnic blood flow and cause bowel ischaemia especially in the period of circulatory instability early post-implant. The aim of the present studies was to compare the incidence of gastrointestinal (GI) complications in patients having a non-pulsatile device with the incidence in those having a pulsatile device...
February 2, 2019: Heart, Lung & Circulation
Neil A Smart
No abstract text is available yet for this article.
February 2, 2019: Heart, Lung & Circulation
Ji Quan Samuel Koh, Himawan Fernando, Karlheinz Peter, Dion Stub
BACKGROUND: Traditionally, opioids have been the analgesia of choice for patients with ST-Elevation Myocardial Infarction (STEMI). Recent studies, however, have raised the possibility of harmful effects of opioid administration through delayed onset of antiplatelet agents. OBJECTIVE: To perform a systematic review of the effects of parenteral opioids in patients presenting with STEMI. METHODS: Medical databases were systematically searched to 28 February 2018...
February 1, 2019: Heart, Lung & Circulation
Yinghao Sun, Jie Li, Ruixin Fan, Guang Li, Ming Fu, Songyuan Luo, Huanyu Ding, Jianfang Luo
BACKGROUND: Superiority of the new-generation, self-expanding Evolut R compared with the first-generation CoreValve on outcomes after transcatheter aortic valve implantation (TAVI) is unclear. This meta-analysis sought to investigate the outcomes of Evolut R vs CoreValve after TAVI. METHODS: A systematic review of studies comparing outcomes of Evolut R and CoreValve after TAVI was performed through PubMed, EMBASE and Cochrane Library. Crude risk ratios (RRs) were calculated with 95% confidence intervals using a random effects model...
January 28, 2019: Heart, Lung & Circulation
Hesham R Omar, Maya Guglin
BACKGROUND: Diuretic requirements in patients with acute decompensated heart failure (ADHF) and hyponatraemia versus normonatraemia on admission has not been previously explored. METHODS: The Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) trial dataset was utilised to examine the characteristics and diuretic requirements of patients with ADHF with hyponatraemia or normonatraemia on admission. RESULTS: Patients with ADHF and admission hyponatraemia (n = 103, average Na 130...
January 28, 2019: Heart, Lung & Circulation
Niranjan Bidargaddi, Geoffrey Schrader, Graeme Tucker, Rohan Dhillon, Anand Ganesan
BACKGROUND: Increasingly, big data derived from administrative hospital records can be subject to analytics to provide clinical insights. The aim of this study was to determine the impact of psychiatric comorbidity on length of hospital stay and number of hospital admissions in cardiac patients utilising routinely collected hospitalisation records. METHODS: We routinely collected clinical and socio-demographic variables extracted from 37,580 cardiac patients, between 18 and 65 years old, admitted to South Australian hospitals between 2001/02 to 2010/11 financial years with cardiac diagnoses used to derive patient level and separation level variables used in the modelling...
January 28, 2019: Heart, Lung & Circulation
Emma Thomas, Sherry L Grace, Douglas Boyle, Robyn Gallagher, Lis Neubeck, Nicholas Cox, Jo-Anne Manski-Nankervis, Sandra Henley-Smith, Dominique A Cadilhac, Adrienne O'Neil
BACKGROUND: Clinical registries are effective for monitoring clinical practice, yet manual data collection can limit their implementation and sustainability. The objective of this study was to assess the feasibility of using a data capture tool to collect cardiac rehabilitation (CR) minimum variables from electronic hospital administration databases to populate a new CR registry in Australia. METHODS: Two CR facilities located in Melbourne, Australia participated, providing data on 42 variables including: patient socio-demographics, risk factors and co-morbidities, CR program information (e...
January 28, 2019: Heart, Lung & Circulation
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