journal
https://read.qxmd.com/read/38182893/a-neuronal-subcompartment-view-of-atp-production
#21
JOURNAL ARTICLE
Darran Yates
No abstract text is available yet for this article.
January 5, 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38177700/a-neuronal-cluster-involved-in-arousal-and-breathing
#22
JOURNAL ARTICLE
Darran Yates
No abstract text is available yet for this article.
January 4, 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38177699/promoting-axon-regeneration-after-injury
#23
JOURNAL ARTICLE
Darran Yates
No abstract text is available yet for this article.
January 4, 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38172626/understanding-neural-circuit-function-through-synaptic-engineering
#24
REVIEW
Ithai Rabinowitch, Daniel A Colón-Ramos, Michael Krieg
Synapses are a key component of neural circuits, facilitating rapid and specific signalling between neurons. Synaptic engineering - the synthetic insertion of new synaptic connections into in vivo neural circuits - is an emerging approach for neural circuit interrogation. This approach is especially powerful for establishing causality in neural circuit structure-function relationships, for emulating synaptic plasticity and for exploring novel patterns of circuit connectivity. Contrary to other approaches for neural circuit manipulation, synaptic engineering targets specific connections between neurons and functions autonomously with no user-controlled external activation...
January 3, 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38263216/goal-directed-learning-in-adolescence-neurocognitive-development-and-contextual-influences
#25
REVIEW
Linda Wilbrecht, Juliet Y Davidow
Adolescence is a time during which we transition to independence, explore new activities and begin pursuit of major life goals. Goal-directed learning, in which we learn to perform actions that enable us to obtain desired outcomes, is central to many of these processes. Currently, our understanding of goal-directed learning in adolescence is itself in a state of transition, with the scientific community grappling with inconsistent results. When we examine metrics of goal-directed learning through the second decade of life, we find that many studies agree there are steady gains in performance in the teenage years, but others report that adolescent goal-directed learning is already adult-like, and some find adolescents can outperform adults...
March 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38212413/causation-in-neuroscience-keeping-mechanism-meaningful
#26
REVIEW
Lauren N Ross, Dani S Bassett
A fundamental goal of research in neuroscience is to uncover the causal structure of the brain. This focus on causation makes sense, because causal information can provide explanations of brain function and identify reliable targets with which to understand cognitive function and prevent or change neurological conditions and psychiatric disorders. In this research, one of the most frequently used causal concepts is 'mechanism' - this is seen in the literature and language of the field, in grant and funding inquiries that specify what research is supported, and in journal guidelines on which contributions are considered for publication...
February 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38191721/data-driven-modelling-of-neurodegenerative-disease-progression-thinking-outside-the-black-box
#27
REVIEW
Alexandra L Young, Neil P Oxtoby, Sara Garbarino, Nick C Fox, Frederik Barkhof, Jonathan M Schott, Daniel C Alexander
Data-driven disease progression models are an emerging set of computational tools that reconstruct disease timelines for long-term chronic diseases, providing unique insights into disease processes and their underlying mechanisms. Such methods combine a priori human knowledge and assumptions with large-scale data processing and parameter estimation to infer long-term disease trajectories from short-term data. In contrast to 'black box' machine learning tools, data-driven disease progression models typically require fewer data and are inherently interpretable, thereby aiding disease understanding in addition to enabling classification, prediction and stratification...
February 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38182894/mistaken-identity
#28
JOURNAL ARTICLE
Sian Lewis
No abstract text is available yet for this article.
February 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38182892/orchestrating-axonal-organization
#29
JOURNAL ARTICLE
Lisa Heinke
No abstract text is available yet for this article.
February 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38135796/self-recognition-mirrored-from-others
#30
JOURNAL ARTICLE
Jake Rogers
No abstract text is available yet for this article.
February 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38114784/controlling-communication
#31
JOURNAL ARTICLE
Katherine Whalley
No abstract text is available yet for this article.
February 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38102444/benefit-worth-the-cost
#32
JOURNAL ARTICLE
Jake Rogers
No abstract text is available yet for this article.
February 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38066307/preparing-for-motherhood
#33
JOURNAL ARTICLE
Katherine Whalley
No abstract text is available yet for this article.
February 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38049610/the-neurobiology-of-sars-cov-2-infection
#34
REVIEW
Jenny Meinhardt, Simon Streit, Carsten Dittmayer, Regina V Manitius, Helena Radbruch, Frank L Heppner
Worldwide, over 694 million people have been infected with SARS-CoV-2, with an estimated 55-60% of those infected developing COVID-19. Since the beginning of the pandemic in December 2019, different variants of concern have appeared and continue to occur. With the emergence of different variants, an increasing rate of vaccination and previous infections, the acute neurological symptomatology of COVID-19 changed. Moreover, 10-45% of individuals with a history of SARS-CoV-2 infection experience symptoms even 3 months after disease onset, a condition that has been defined as 'post-COVID-19' by the World Health Organization and that occurs independently of the virus variant...
January 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38036709/the-generative-grammar-of-the-brain-a-critique-of-internally-generated-representations
#35
REVIEW
George Dragoi
The past decade of progress in neurobiology has uncovered important organizational principles for network preconfiguration and neuronal selection that suggest a generative grammar exists in the brain. In this Perspective, I discuss the competence of the hippocampal neural network to generically express temporally compressed sequences of neuronal firing that represent novel experiences, which is envisioned as a form of generative neural syntax supporting a neurobiological perspective on brain function. I compare this neural competence with the hippocampal network performance that represents specific experiences with higher fidelity after new learning during replay, which is envisioned as a form of neural semantic that supports a complementary neuropsychological perspective...
January 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38036708/the-long-covid-haul
#36
JOURNAL ARTICLE
Sian Lewis
No abstract text is available yet for this article.
January 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/38030800/from-local-app-expression-to-network-dysfunction
#37
JOURNAL ARTICLE
Darran Yates
No abstract text is available yet for this article.
January 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/37996703/human-neuronal-maturation-comes-of-age-cellular-mechanisms-and-species-differences
#38
REVIEW
Jenelle L Wallace, Alex A Pollen
The delayed and prolonged postmitotic maturation of human neurons, compared with neurons from other species, may contribute to human-specific cognitive abilities and neurological disorders. Here we review the mechanisms of neuronal maturation, applying lessons from model systems to understand the specific features of protracted human cortical maturation and species differences. We cover cell-intrinsic features of neuronal maturation, including transcriptional, epigenetic and metabolic mechanisms, as well as cell-extrinsic features, including the roles of activity and synapses, the actions of glial cells and the contribution of the extracellular matrix...
January 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/37968453/playing-tag-at-the-axon
#39
JOURNAL ARTICLE
Lisa Heinke
No abstract text is available yet for this article.
January 2024: Nature Reviews. Neuroscience
https://read.qxmd.com/read/37964133/sometimes-science-needs-a-stubborn-mind-the-discovery-of-dopamine
#40
JOURNAL ARTICLE
Federica De Lazzari
No abstract text is available yet for this article.
January 2024: Nature Reviews. Neuroscience
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