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Otology & Neurotology

Zhao Ellen Peng, Christi Hess, Jenny R Saffran, Jan R Edwards, Ruth Y Litovsky
HYPOTHESIS: Children of 2 to 3 years old with cochlear implants can perform consonant discriminations using fine-grained acoustic cues. BACKGROUND: Children born with severe-to-profound deafness are provided with early cochlear implantation (<2 yr) to maximize oral communication outcomes. Little is known regarding their abilities to discriminate consonant contrasts for accurately identifying speech sounds. METHODS: Using a Reaching for Sound paradigm to collect behavioral responses, consonant contrast discrimination was measured in 13 children with bilateral cochlear implants (BiCIs; aged 28-37 mo), and 13 age-matched normal-hearing (NH) children...
January 24, 2019: Otology & Neurotology
Julia Sjögren, Måns Magnusson, Fredrik Tjernström, Mikael Karlberg
OBJECTIVE: To present findings that suggest steroid treatment within 24 hours of onset of vestibular neuronitis results in better restitution of vestibular function than treatment between 25 and 72 hours. PATIENTS: Thirty-three consecutive patients (17 men, 16 women, mean age 57 yr, range 17-85 yr) with acute vestibular neuronitis and treated with steroids within 72 hours after symptom onset. Patients were divided into two groups depending on if they were treated within the first 24 hours or not...
January 22, 2019: Otology & Neurotology
Daniel Dejaco, David Riedl, Timo Gottfried, Thomas Rasse, Natalie Fischer, David Prejban, Viktor Koci, Herbert Riechelmann, Joachim Schmutzhard, Thomas Keintzel
OBJECTIVE: If mixed-hearing-loss (MHL) occurs in otosclerosis, hearing-aids (HA) in addition to conventional-stapedotomy (SDT) may be necessary. If otosclerosis progresses or technical or medical problems prevent use of HA, combining active-middle-ear-implants (AMEI) with SDT ("power-piston") may be considered. Previously, AMEI-coupling to the long-incudial-process was suggested. Here, a "modified-power-piston" surgery (mPP) coupling to the short-incudial-process was proposed, so no coupling over the positioned stapes-piston is required...
January 17, 2019: Otology & Neurotology
Nathan Chin-Yau Tu, Gabriela Bobarnac Dogaru, Polly Huang, Jeehong Kim, Bernadette Diegnan, John Louie Go, Rick Adam Friedman
OBJECTIVE: Cochlear fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI) signal intensity has been shown to be elevated in patients with vestibular schwannomas (VS). This study evaluated the preoperative and postoperative cochlear signal on FLAIR sequences in patients undergoing hearing preservation surgery. STUDY DESIGN: Retrospective chart review. SETTING: Tertiary referral center. PATIENTS: All patients undergoing middle cranial fossa or retrosigmoid craniotomy for VS at a single institution from September 2013 to January 2017 were screened...
January 16, 2019: Otology & Neurotology
Mathieu Petremann, Charlotte Romanet, Audrey Broussy, Christophe Tran Van Ba, Sonia Poli, Jonas Dyhrfjeld-Johnsen
HYPOTHESIS: SENS-401 (R-azasetron besylate) is effective against severe acoustic trauma-induced hearing loss. BACKGROUND: SENS-401 has calcineurin inhibiting properties and attenuates cisplatin-induced hearing loss in a rat model. Cisplatin-induced and acoustic trauma-induced hearing loss share common apoptotic pathways. METHODS: The dose-response relationship of SENS-401 (6.6 mg/kg BID, 13.2 mg/kg BID, 26.4 mg/kg QD) and treatment time-window (13...
December 17, 2018: Otology & Neurotology
Henryk Skarzynski, Artur Lorens, Beata Dziendziel, Piotr H Skarzynski
OBJECTIVE: To report the improvement in hearing preservation and speech understanding of five pediatric patients who received cochlear implantation via Electro-natural Stimulation Partial Deafness Treatment, the largest group so far treated. STUDY DESIGN: Retrospective case review. SETTING: Tertiary referral center. PATIENTS: A series of five children aged 9 to 16 years old with bilateral normal hearing at 125 to 1500 Hz and severe-to-profound hearing loss above 1500 Hz, who were subjected to unilateral cochlear implantation...
December 17, 2018: Otology & Neurotology
Divya A Chari, Stacey M Frumm, Omar Akil, Aaron D Tward
AIM: To better elucidate the cellular dynamics by which perforations in the tympanic membrane (TM) are healed. BACKGROUND: Under normal conditions, epidermal cells are born and then migrate radially outward from the malleus in the TM. It is unknown what the relative contribution of newly proliferated cells from different lineages is in the healing of TM perforations. METHODS: Thirty-six female mice were used in this study. Ethynyl deoxyuridine, a thymidine analogue that labels newly proliferated cells, was injected intraperitoneally into each mouse and then subsequently supplied in the drinking water...
December 17, 2018: Otology & Neurotology
Dana Oh, Eek-Sung Lee, Dong-Seong Shin, Tae-Kyeong Lee
No abstract text is available yet for this article.
December 13, 2018: Otology & Neurotology
Franca Wagner, Melanie Buchwalder, Roland Wiest, Marco D Caversaccio, Dominique Vibert
OBJECTIVE: To compare the neurotological results of five patients suffering from progressive hearing loss and ataxia due to superficial siderosis (SS) with the magnetic resonance imaging (MRI) findings. STUDY DESIGN: Retrospective case review. SETTING: Primary and hospital care center. PARTICIPANTS: Five adult patients with neurotological symptoms of SS underwent MRI with acquisition of our temporal bone protocol including 3D-constructive interference in steady state (3D-CISS) and susceptibility-weighted imaging (SWI)...
December 3, 2018: Otology & Neurotology
Andrew Causon, Martin O'Driscoll, Emma Stapleton, Simon Lloyd, Simon Freeman, Kevin J Munro
OBJECTIVE: Electrically evoked auditory brainstem responses (eABRs) can be recorded before cochlear implant (CI) surgery to verify auditory nerve function, and is particularly helpful in to assess the function of the auditory nerve in cases of auditory nerve hypoplasia. This is the first study to compare three preimplant eABRs recording techniques: 1) standard extracochlear, 2) novel intracochlear, and 3) conventional intracochlear with the CI. STUDY DESIGN: A within-participants design was used where eABRs were sequentially measured during CI surgery using three methods with stimulation from: 1) an extracochlear electrode placed at the round window niche, 2) two different electrodes on a recently developed Intracochlear Test Array (ITA), and 3) two different electrodes on a CI electrode array...
November 27, 2018: Otology & Neurotology
Baiya Li, Yuan Deng, Lin'gu Wang, Yuan Shao
No abstract text is available yet for this article.
March 2019: Otology & Neurotology
Andrew J Thomas, Geoffrey C Casazza, Joel D MacDonald, Richard K Gurgel
OBJECTIVES: We describe the first known case of coexistent vestibular schwannoma (VS) and Creutzfeldt-Jakob disease (CJD). Our objectives are to use this case as a general lesson for the subspecialist otolaryngologist to remain vigilant to alternative diagnoses, and to specifically improve understanding of the diagnosis and management of CJD as relevant to the practice of otolaryngology and skull base surgery. METHODS: Retrospective case review performed in June 2016 at an academic, tertiary, referral center...
March 2019: Otology & Neurotology
Kathryn Y Noonan, Fred H Linthicum, Ivan A Lopez, Akira Ishiyama, Mia E Miller
HYPOTHESIS: In children, the distance between the carotid canal (CC) and Eustachian tube (ET) is not significantly narrower than the adult population. BACKGROUND: ET dysfunction treated with ET dilation is FDA approved for adults. Several studies describe the close relationship between the CC and the ET in adults, but the anatomy of the ET has not been well defined in children. This study seeks to investigate these relationships in the pediatric population. METHODS: Histologic sections from 23 temporal bones of pediatric patients ages 0 to 18 were reviewed by two independent observers...
March 2019: Otology & Neurotology
Jack Birkenbeuel, Kimberly Vu, Brandon M Lehrich, Mehdi Abouzari, Dillon Cheung, Pooya Khosravi, Ronald Sahyouni, Kasra Ziai, Omid Moshtaghi, Sammy Sahyouni, Hamid R Djalilian
OBJECTIVES: To analyze medical malpractice lawsuit trends pertaining to cases of vestibular schwannomas (VS). METHODS: Two major computerized legal databases (LexisNexis and WestLaw) were queried and reviewed for evaluation of all the US state and federal court records from civil trials alleging malpractice between 1976 and 2016. RESULTS: A total of 32 VS cases were identified. Allegations were divided into four categories: misdiagnosis/delayed diagnosis (47%), postoperative complications (44%), failure of informed consent or information sharing (16%), and other (3%)...
March 2019: Otology & Neurotology
Jorge Rey-Martinez, Elisabeth Ninchritz, Idoia Palicio, Miren Goiburu, Carmen Maria Casado, Xabier Altuna
OBJECTIVE: To investigate the clinical validity of the mathematical measured VVOR test results to detect horizontal semicircular canal hypofunction. STUDY DESIGN: Prospective, nonrandomized, observational study. SETTING: Tertiary referral center, hospital. PATIENTS: Consecutive patients on first time visit to otoneurology unit. INTERVENTION(S): Diagnostic. MAIN OUTCOME MEASURE(S): Values of statistical indicators of clinical validity for VVOR test to detect horizontal canal hypofunction were used considering vHIT horizontal aVOR gain values as gold standard...
March 2019: Otology & Neurotology
Aki Inoue, Shinichi Iwasaki, Chisato Fujimoto, Makoto Kinoshita, Tatsuya Yamasoba
OBJECTIVE: To evaluate the progression of peripheral vestibular dysfunction in patients with an A-to-G point mutation at nucleotide pair 3243 in mitochondrial DNA (A3243G mutation). STUDY DESIGN: Retrospective patient series. SETTING: Tertiary referral center. PATIENTS: Six unrelated patients with an A3243G mutation (four mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes; and two maternally inherited diabetes and deafness; five females and one male; average age 41 ± 11...
March 2019: Otology & Neurotology
Ivo J Kruyt, Herman Kok, Arjan Bosman, Rik Chrétien Nelissen, Emmanuel Antonia Maria Mylanus, Myrthe Karianne Sofie Hol
OBJECTIVES: To evaluate the three-year clinical and audiological outcomes of soft-tissue preservation compared to soft-tissue reduction in linear incision surgery for percutaneous implant for bone conduction (BC) devices. METHODS: Twenty-five patients (25 implants) were enrolled in a prospective cohort for implant surgery with linear incision and tissue preservation. The control group consisted of 25 patients (25 implants) from a previous randomized controlled trial in which a linear incision with soft-tissue reduction was applied...
March 2019: Otology & Neurotology
Jérémie Guignard, Pascal Senn, Roger Koller, Marco Caversaccio, Martin Kompis, Georgios Mantokoudis
OBJECTIVE: The objective of this study was to investigate the benefit of mobile Voice over Internet protocol (VoIP) over conventional mobile phone calls (Global System for Mobile Communications, GSM) on speech intelligibility and quality for cochlear implant (CI) recipients. STUDY DESIGN: Cross-sectional, prospective. SETTING: Tertiary referral center. PATIENTS: A volunteer sample of experienced, German-speaking, adult CI recipients was considered...
March 2019: Otology & Neurotology
Anne K Maxwell, Stephen P Cass
OBJECTIVE: Current clinical practice for fixation of the cochlear implant receiver-stimulator (RS) may not follow recommended manufacturer's guidelines. We investigated short- and long-term RS migration using a subperiosteal pocket technique via serial objective position measurements since previous literature provided only subjective or short-term evaluation. STUDY DESIGN: Retrospective review. SETTING: Tertiary referral center. PATIENTS: We reviewed all patients who underwent cochlear implantation by the senior author between 2012 and 2018...
March 2019: Otology & Neurotology
Jungmin Ahn, Gwanghui Ryu, Yang-Sun Cho
OBJECTIVE: The purpose of this study was to assess the long-term changes in music perception among cochlear implant (CI) patients using the Korean version of the Clinical Assessment of Music Perception test and questionnaires for music listening. METHODS: Twenty-seven CI patients participated in this study. Their music perception ability was evaluated using the Korean version of the Clinical Assessment of Music Perception test, which consisted of pitch discrimination, melody, and timbre identification...
March 2019: Otology & Neurotology
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