Bruno Coêlho Cavalcanti, Islay Lima Magalhães, Danilo Damasceno Rocha, Francisco Stefânio Barreto, João Batista de Andrade Neto, Hemerson Iury Ferreira Magalhães, Cláudio Costa Dos Santos, Manoel Odorico de Moraes
Croton heliotropiifolius Kunth, popularly known as "velame," is a shrub that resides in northeastern Brazil. The essential oil of C. heliotropiifolius contains high concentrations of volatile compounds in the leaves and is widely used in folk medicine for many purposes as an antiseptic, analgesic, sedative, and anti-inflammatory agent. Due to the apparent limited amount of information, the aim of this study was to determine the cytotoxic potential of essential oil extracted from leaves of C. heliotropiifolius , utilizing different human cancer cell lines (HL-60, leukemia; HCT-116, colon; MDA-MB435, melanoma; SF295, glioblastoma) and comparison to murine fibroblast L929 cell line...
November 6, 2023: Journal of Toxicology and Environmental Health. Part A