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Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi

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https://read.qxmd.com/read/30713004/identification-of-a-novel-protein-in-the-genome-sequences-of-leptospira-interrogans-with-the-ability-to-interact-with-host-s-components
#1
A D Rossini, A F Teixeira, A Souza Filho, G O Souza, S A Vasconcellos, M B Heinemann, E C Romero, A L T O Nascimento
BACKGROUND: Leptospirosis is an infectious disease that affects humans and animals worldwide. The etiological agents of this disease are the pathogenic species of the genus Leptospira. The mechanisms involved in the leptospiral pathogenesis are not full understood. The elucidation of novel mediators of host-pathogen interaction is important in the detection of virulence factors involved in the pathogenesis of leptospirosis. OBJECTIVE: This work focused on identification and characterization of a hypothetical protein of Leptospira encoded by the gene LIC10920...
January 22, 2019: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30686615/distribution-of-virulence-genes-in-bacteremic-methicillin-resistant-staphylococcus-aureus-isolates-from-various-sources
#2
Fu-Der Wang, Ping-Feng Wu, Su-Jung Chen
BACKGROUND/PURPOSE: Methicillin-resistant Staphylococcus aureus (MRSA) can encode proteins which directly bind bacteria to many tissues and medical devices or catheters to trigger pathogenesis. However, the relationship between genetic backgrounds and virulent factors in MRSA isolates remained incompletely understood yet. METHODS: MRSA isolates were collected from blood cultures of patients with infective endocarditis, bone/joint infection, skin/soft tissue infection, or catheter-related bacteremia in hemodialysis at a tertiary medical center between 2005 and 2011...
January 10, 2019: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30665844/microbiology-of-peritoneal-dialysis-related-infection-and-factors-of-refractory-peritoneal-dialysis-related-peritonitis-a-ten-year-single-center-study-in-taiwan
#3
Hsin-Hui Wang, Chung-Hao Huang, Mei-Chuan Kuo, Shang-Yi Lin, Chin-Huei Hsu, Chun-Yuan Lee, Yi-Wen Chiu, Yen-Hsu Chen, Po-Liang Lu
BACKGROUND: Peritoneal dialysis (PD)-related infection is a serious complication of patients with PD. Refractory peritonitis may lead to failure of PD, shift to hemodialysis (HD) or death. Besides, microbiologic resistance increased worldwide that might impact the treatment choice for such infections. Investigating the causative pathogens and risk factors of PD-related infections in Taiwan was warranted. METHODS: This is a retrospective study involving patients with PD from 2007 to 2016 in a southern Taiwan hospital...
January 8, 2019: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30661953/postoperative-mycobacteroides-abscessus-subsp-abscessus-endophthalmitis-clinical-analysis-of-12-clustered-adults-and-a-proposed-therapeutic-algorithm
#4
Jia-Horung Hung, Wen-Chien Ko, Chau-Yin Chen, Sheng-Hsiang Lin, Cheng-Lin Wu, Sheng-Min Hsu, Yu-Ti Teng, Shih-Hao Wang, Sung-Huei Tseng, Fu-Chin Huang, Chun-Chieh Lai, Ching-Lung Chen, Chien-Hsiung Lai, Po-Lin Chen, Evelyn Jou-Chen Huang
PURPOSE: Postoperative endophthalmitis caused by nontuberculous mycobacterium is a rare but devastating complication after intraocular surgery. However, optimal treatment strategies remain undetermined in view of its rarity. METHODS: We investigated the cases of culture-proven postoperative Mycobacteroides abscessus subsp. abscessus endophthalmitis in southern Taiwan, focusing on clinical manifestations and microbiological study, and aimed to describe clinical staging and to propose a therapeutic modality for this disease...
January 6, 2019: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30772212/evaluation-of-vitek-ms-clin-tof-ii-ms-autof-ms-1000-and-vitek-2-anc-card-for-identification-of-bacteroides-fragilis-group-isolates-and-antimicrobial-susceptibilities-of-these-isolates-in-a-chinese-university-hospital
#5
Yao Wang, Xin-Fei Chen, Xiu-Li Xie, Meng Xiao, Yang Yang, Ge Zhang, Jing-Jia Zhang, Si-Meng Duan, Qian Zhang, Peng Zhang, Clement Tsui, Ying-Chun Xu
BACKGROUND AND PURPOSE: Bacteroides fragilis group isolates are most frequently isolated anaerobic pathogens. This study aimed to evaluate the accuracy of VITEK MS, Clin-ToF-II MS, Autof MS 1000 and VITEK 2 ANC card on the identification of clinical B. fragilis group isolates, as well as to determine their antimicrobial susceptibilities. METHODS: A total of 138 isolates of B. fragilis group isolates were identified with the three MALDI-TOF MS systems and VITEK 2 ANC cards...
January 4, 2019: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30642809/long-term-outcomes-in-lupus-patients-receiving-different-renal-replacement-therapy
#6
Wan-Ting Tsai, Hung-Chi Chang, Chen-Ti Wang, Bor-Luen Chiang, Yu-Tsan Lin
BACKGROUND/PURPOSE: To compare the long-term outcomes and survival rates of patients with end stage renal disease (ESRD) caused by lupus nephritis who received three different modalities of renal replacement therapy, including hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation (KT). METHODS: We retrospectively analyzed 94 patients with ESRD caused by lupus nephritis. Among these, 42 received HD, 12 received PD, and 40 underwent KT. The adverse events, survival data and cause of mortality were recorded...
January 4, 2019: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30638785/synergistic-effect-of-linezolid-with-fosfomycin-against-staphylococcus-aureus-in-vitro-and-in-an-experimental-galleria-mellonella-model
#7
Lan Li, Hao Chen, Yanyan Liu, Shuangli Xu, Maomao Wu, Zhou Liu, Caifen Qi, Guijun Zhang, Jiabin Li, Xiaohui Huang
BACKGROUND/PURPOSES: Treatment of Staphylococcus aureus infections is challenging owing to widespread multidrug resistance. There is now considerable interest in the potential of combination therapies. Although linezolid/fosfomycin combination appears to be a promising treatment option based on in vitro data, further preclinical work is needed. In this study, the Galleria mellonella system was employed to study the in vivo efficacy of this combination in order to determine whether it should be explored further for the treatment of S...
December 31, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30683627/nut-sensitization-profile-in-southern-taiwan
#8
Chih-Wei Cheng, Yung-Chih Lin, Bao-Ren Nong, Po-Yen Liu, Yung-Feng Huang, Ling-Ying Lu, Herng-Sheng Lee
BACKGROUND/PURPOSE: To evaluate the relationship between serum-specific immunoglobulin E (IgE) to peanuts/tree nuts and their clinical manifestations in atopic diseases. METHOD: Serum from people with the classical symptoms of asthma, allergic rhinitis (AR), or atopic dermatitis (AD) was collected for the measurement of serum-specific IgE to peanuts, cashew nuts, Brazil nuts, almonds, and coconuts. Cases with possible sensitization to these nuts (serum specific IgE ≧ 0...
December 27, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30612922/roles-of-toll-like-receptor-4-for-cellular-pathogenesis-in-primary-open-angle-glaucoma-a-potential-therapeutic-strategy
#9
REVIEW
Teera Poyomtip
In recent years, glaucoma has been proposed as an autoimmune disease and an understanding immune-regulation concept has been applied for novel glaucoma therapy. Current evidence suggests an innate immunity is a keystone step for primary open angle glaucoma (POAG) pathogenesis resulting from trabecular meshwork (TM) cell fibrosis and retinal ganglion cell (RGC) death. Toll-like receptor 4 (TLR4) is a common player in the innate immunity, which appears on the TM and RGC of POAG. The activation of TLR4 regulates several molecules involving both fibrosis and cell death...
December 27, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30709717/deep-sequencing-reveals-multiclonality-and-new-discrete-typing-units-of-trypanosoma-cruzi-in-rodents-from-the-southern-united-states
#10
Henry Pronovost, Anna C Peterson, Bruno Ghersi Chavez, Michael J Blum, Eric Dumonteil, Claudia P Herrera
BACKGROUND/PURPOSE: The parasitic protozoa Trypanosoma cruzi, is widely distributed throughout the Americas. We explored the nature of T. cruzi infection in small rodents from New Orleans (LA, USA), an enzootic region of the parasite in North America. METHODS: We characterized the full complement of discrete typing units (DTUs) in rodent hosts through next-generation metabarcoding, as conventional PCR and Sanger sequencing approaches only detect the dominant genotype in biological samples...
December 21, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30616912/integrated-safety-summary-of-phase-ii-and-iii-studies-comparing-oral-nemonoxacin-and-levofloxacin-in-community-acquired-pneumonia
#11
Shih-Lung Cheng, Ren-Guang Wu, Yin-Ching Chuang, Wann-Cherng Perng, Shih-Ming Tsao, Yu-Ting Chang, Li-Wen Chang, Ming-Chu Hsu
BACKGROUND: Nemonoxacin, a novel nonfluorinated quinolone, has broad-spectrum antibacterial activity, including activity against antibiotic-resistant strains, and was developed for treating community-acquired pneumonia (CAP). This report provides an integrated safety summary of oral nemonoxacin from two phase II and one phase III clinical studies. METHODS: Patients with mild CAP were randomized for treatment with nemonoxacin 500 mg (NEMO-500MG), nemonoxacin 750 mg (NEMO-750MG), or levofloxacin 500 mg (LEVO), orally, once daily, for 7-10 days...
December 21, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30630711/the-role-of-5-methoxytryptophan-in-pediatric-onset-lupus-nephritis-a-retrospective-cohort-study
#12
Ting-Chun Lin, Cheng-Chin Kuo, Chao-Yi Wu, Kuo-Wei Yeh, Ming-Ling Kuo, Jing-Long Huang
BACKGROUND: This clinical study investigates the role of 5-methoxytryptophan (5-MTP) in pediatric systemic lupus erythematosus (SLE), with a particular interest in lupus nephritis (LN). PATIENTS AND METHODS: One hundred ten children with SLE were enrolled in the cohort study. Among the patients, seventy-seven (70%) had active LN and thirty-three (30%) were not present with LN during their first visit to the clinic. The diagnoses of LN were biopsy-proven. Serum samples were collected before and after administration of immunosuppressive medications to evaluate 5-MTP levels and regular laboratory data...
December 19, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30598425/the-clinical-features-and-mortality-risk-factors-of-cytomegalovirus-infection-in-patients-with-systemic-lupus-erythematosus
#13
MingLi Hung, Deh-Feng Huang, Wei-Sheng Chen, Chien-Chih Lai, Ming-Han Chen, Hsien-Tzung Liao, Chang-Youh Tsai
BACKGROUND: The clinical features and outcomes of cytomegalovirus (CMV) diseases in patients with systemic lupus erythematosus (SLE) are unknown. We analyzed such data from a medical center in Taiwan. METHODS: We retrospectively reviewed the medical records of patients with SLE who were diagnosed with CMV diseases between 2006 and 2016 in Taipei Veterans General Hospital Taiwan. Clinical and laboratory parameters and treatment outcomes were analyzed. RESULTS: The study enrolled 56 eligible patients with CMV diseases and separated them into survival (n = 24) and mortality (n = 32) groups...
December 16, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30591259/high-correlation-between-human-rhinovirus-type-c-and-children-with-asthma-exacerbations-in-taiwan
#14
Yu-Tsun Su, Yen-Ting Lin, Ching-Chi Yang, Shang-Shyue Tsai, Jiu-Yao Wang, Ya-Ling Huang, Ting-I Lin, Tsun-Mei Lin, Yu-Cheng Tsai, Hong-Ren Yu, Ching-Chung Tsai, Ming-Chun Yang
BACKGROUND/PURPOSES: Human rhinovirus type C (HRV-C) has been associated with asthma exacerbation (AE) in children in several countries. However, in Taiwan the association between HRV, especially HRV-C, and AE in children has yet to be elucidated. We sought to investigate the prevalence of respiratory viruses in children with acute lower respiratory tract infection (ALRTI) in Taiwan and the association between different types of HRV and AE in children. METHODS: This prospective study was conducted from 2011 to 2013, and enrolled children with ALRTI, including an asthma exacerbation group (AE; n = 28) and a Non-asthma group (n = 66)...
December 15, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30583941/immune-response-to-asymptomatic-infections-by-entamoeba-histolytica-and-other-enteric-pathogens-in-pregnant-women-and-their-infants-in-a-high-hiv-burdened-setting-in-zimbabwe
#15
Agness Farai Nhidza, Thajasvarie Naicker, Babill Stray-Pedersen, Tawanda Jonathan Chisango, Edson Panganayi Sibanda, Aziah Ismail, Tsitsi Bandason, Curtis Makaza, Kerina Duri, Takafira Mduluza
BACKGROUND: Asymptomatic Entamoeba histolytica infections in pregnant women puts infants at risk of infection through vertical transmission or transmission during breastfeeding in high HIV prevalence areas. The study aimed at investigating the immune response to asymptomatic E.histolytica infection in pregnant women and their infants in a high HIV burdened setting in Harare, Zimbabwe. METHODOLOGY: Serum samples from 39 predominantly breastfeeding mother-infant pairs were analyzed for inflammatory cytokine and immunoglobulin profiles using BIOPLEX...
December 7, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30612923/recommendations-and-guidelines-for-the-treatment-of-pneumonia-in-taiwan
#16
Chih-Chen Chou, Ching-Fen Shen, Su-Jung Chen, Hsien-Meng Chen, Yung-Chih Wang, Wei-Shuo Chang, Ya-Ting Chang, Wei-Yu Chen, Ching-Ying Huang, Ching-Chia Kuo, Ming-Chi Li, Jung-Fu Lin, Shih-Ping Lin, Shih-Wen Ting, Tzu-Chieh Weng, Ping-Sheng Wu, Un-In Wu, Pei-Chin Lin, Susan Shin-Jung Lee, Yao-Shen Chen, Yung-Ching Liu, Yin-Ching Chuang, Chong-Jen Yu, Li-Ming Huang, Meng-Chih Lin
Pneumonia is a leading cause of death worldwide, ranking third both globally and in Taiwan. This guideline was prepared by the 2017 Guidelines Recommendations for Evidence-based Antimicrobial agents use in Taiwan (GREAT) working group, formed under the auspices of the Infectious Diseases Society of Taiwan (IDST). A consensus meeting was held jointly by the IDST, Taiwan Society of Pulmonary and Critical Care Medicine (TSPCCM), the Medical Foundation in Memory of Dr. Deh-Lin Cheng, the Foundation of Professor Wei-Chuan Hsieh for Infectious Diseases Research and Education and CY Lee's Research Foundation for Pediatric Infectious Diseases and Vaccines...
December 6, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30528336/bloodstream-infections-in-hospitalized-adults-with-dengue-fever-clinical-characteristics-and-recommended-empirical-therapy
#17
Ling-Shan Syue, Hung-Jen Tang, Yuan-Pin Hung, Po-Lin Chen, Chia-Wen Li, Ming-Chi Li, Pei-Fang Tsai, Ching-Chuan Liu, Nan-Yao Lee, Wen-Chien Ko
BACKGROUND: Dengue is an important mosquito-borne tropical viral disease and dual infection, though rare, has been regarded as a risk factor for severe disease and mortality. However, few studies focused on bloodstream infections (BSIs) and empirical antibiotic therapy rarely addressed. METHODS: Dengue patients with concurrent or subsequent BSIs between July 1 and December 31, 2015 were included. Clinical information, laboratory data, and drug susceptibility data were collected...
November 23, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30503389/potential-role-of-autophagy-in-proteolysis-in-trichomonas-vaginalis
#18
Kuo-Yang Huang, Ruei-Min Chen, Hsin-Chung Lin, Wei-Hung Cheng, Hsin-An Lin, Wei-Ning Lin, Po-Jung Huang, Cheng-Hsun Chiu, Petrus Tang
BACKGROUND: Autophagy has been shown to be involved in the pathogenesis of several protists, offering prospects for the developments of new drugs targeting autophagy. However, there is no evidence illustrating functional autophagy in the deep-branching trichomonads. The human parasitic protist Trichomonas vaginalis has been predicted to possess reduced autophagic machinery, with only autophagy-related protein 8 (Atg8) conjugation system required for autophagosome formation. METHODS: The recombinant protein of TvAtg8 (rTvAtg8) and the polyclonal antibody against rTvAtg8 were generated...
November 22, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30497911/subdural-effusion-and-ischemic-stroke-complicating-meningococcal-meningitis-in-an-adult
#19
LETTER
Chun-Yu Chang, Tsung-Lang Chiu, Pau-Yuan Chang, Chih-Ming Hu, Lih-Shinn Wang
No abstract text is available yet for this article.
November 22, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://read.qxmd.com/read/30528335/the-first-case-of-klebsiella-pneumoniae-liver-abscess-with-hemophagocytic-lymphohistiocytosis
#20
LETTER
Ying-Ting Liao, Po-Shen Ko, Yi-Tsung Lin
No abstract text is available yet for this article.
November 20, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
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