journal
https://read.qxmd.com/read/38783663/predictive-parameters-of-the-efficacy-of-varicocele-repair-a-review
#1
JOURNAL ARTICLE
Andrea Crafa, Rossella Cannarella, Rosita A Condorelli, Laura M Mongio├Č, Sandro La Vignera, Aldo E Calogero
Varicocele has a prevalence of 15% in the population and represents a primary cause of infertility in 40% of cases and a secondary cause in approximately 80% of cases. It is considered the major correctable cause of male infertility. Despite its high prevalence in the infertile population, a large number of patients with varicocele do not experience reproductive difficulties. For this reason, it is still highly debated which parameters could be used to predict which patients with varicocele will be most likely to benefit from its repair...
May 24, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38783651/prostate-cancer-screening-and-early-detection
#2
JOURNAL ARTICLE
Orazio Caffo, Antonello Veccia
No abstract text is available yet for this article.
May 24, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38783630/value-of-cognitive-fusion-targeted-and-standard-systematic-transrectal-prostate-biopsy-for-prostate-cancer-diagnosis
#3
JOURNAL ARTICLE
Lu-Ping Yu, Yi-Qing Du, Yi-Ran Sun, Cai-Peng Qin, Wen-Bo Yang, Zi-Xiong Huang, Tao Xu
The aim of this study was to compare the accuracies of cognitive fusion-guided targeted biopsy (TB), systematic biopsy (SB), and combined TB+SB for the detection of prostate cancer (PCa) and clinically significant PCa (csPCa) in males with lesions detected by magnetic resonance imaging (MRI). We conducted a retrospective analysis of individuals who underwent prostate biopsy at Peking University People's Hospital (Beijing, China), with an emphasis on patients with both transrectal TB and SB. The main objective was to determine the precisions of SB, TB, and TB+SB for diagnosing PCa and csPCa...
May 24, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38783616/prostate-cancer-biology-from-clinical-prognostic-low-to-intermediate-risk-groups-looking-up-at-the-multiple-patterns-tracking-the-way-forward
#4
JOURNAL ARTICLE
Antonio Benito Porcaro
No abstract text is available yet for this article.
May 24, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38759095/andrology-laboratory-technique-for-analysis-of-semen-in-men-with-azoospermia
#5
JOURNAL ARTICLE
Andrian Japari, Dharani Moorthy, Amarnath Rambhatla
Discovery of spermatozoa during the 17th century led to developing technologies for semen analysis in the early 1900s, and then, standard techniques were implemented during the 20th century. Semen analysis has a pivotal role in the male infertility evaluation, and azoospermia is an important finding. Azoospermia is identified in 15% of infertile men. However, the accurate laboratory assessment of azoospermia poses certain technical challenges. Laboratories currently perform semen assessment with great variability; thus, a standard method should be used...
May 17, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38748865/comparison-of-systematic-and-combined-biopsy-for-the-detection-of-prostate-cancer
#6
JOURNAL ARTICLE
Jin-Lun Huang, Da Huang, Tsun-Tsun Chun, Chi Yao, Yong-Le Zhan, Xiao-Hao Ruan, Terence Chun-Ting Lai, Chiu-Fung Tsang, Karl-Ho Pang, Ada Tsui-Lin Ng, Dan-Feng Xu, Brian Sze-Ho Ho, Rong Na
Systematic prostate biopsy has limitations, such as overdiagnosis of clinically insignificant prostate cancer and underdiagnosis of clinically significant prostate cancer. Magnetic resonance imaging (MRI)-guided biopsy, a promising alternative, might improve diagnostic accuracy. To compare the cancer detection rates of systematic biopsy and combined biopsy (systematic biopsy plus MRI-targeted biopsy) in Asian men, we conducted a retrospective cohort study of men who underwent either systematic biopsy or combined biopsy at two medical centers (Queen Mary Hospital and Tung Wah Hospital, Hong Kong, China) from July 2015 to December 2022...
May 14, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38748861/association-between-anti-m%C3%A3-llerian-hormone-concentrations-and-sperm-retrieval-outcomes-in-patients-with-idiopathic-nonobstructive-azoospermia-a-systematic-review-and-meta-analysis
#7
JOURNAL ARTICLE
Hong Xiao, Yi-Lang Ding, Peng Yang, Qiang Chen, Hai-Lin Huang, Xi Chen, Hui-Liang Zhou, Song-Xi Tang
Microdissection testicular sperm extraction (mTESE) is commonly performed to retrieve sperm in the testes for assisted reproductive techniques in patients with idiopathic nonobstructive azoospermia (iNOA). However, the success rate of sperm retrieval varies among individuals. We aim to investigate the association between clinical parameters and sperm retrieval outcomes in patients with iNOA. We searched PubMed, EMBASE, and Web of Science from database inception to August 2, 2023. The main measure was whether sperm retrieval was successful in patients with iNOA who underwent mTESE...
May 14, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38738960/molecular-diagnostics-of-prostate-cancer-impact-of-molecular-tests
#8
JOURNAL ARTICLE
Eros Azzalini, Serena Bonin
Prostate cancer (PCa) is the second leading cause of cancer-related death among men. Prostate-specific antigen (PSA) testing is used in screening programs for early detection with a consequent reduction of PCa-specific mortality at the cost of overdiagnosis and overtreatment of the nonaggressive PCa. Recently, several assays have been commercially developed to implement PCa diagnosis, but they have not been included in both screening and diagnosis of PCa. This review aims to describe the actual and novel commercially available molecular biomarkers that can be used in PCa management to implement and tailor the screening and diagnosis of PCa...
May 10, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38738948/evaluation-of-microrna-expression-profiles-in-human-sperm-frozen-using-permeable-cryoprotectant-free-droplet-vitrification-and-conventional-methods
#9
JOURNAL ARTICLE
Li-Xin Zhang, Jing Mao, Yan-Dong Zhou, Guang-Yao Mao, Run-Fa Guo, Hong-Shan Ge, Xia Chen
For sperm cryopreservation, the conventional method, which requires glycerol, has been used for a long time. In addition, the permeable cryoprotectant-free vitrification method has been continuously studied. Although the differences of cryopreservation effects between the two methods have being studied, differences in microRNA (miRNA) profiles between them remain unclear. In this study, we investigated the differences in miRNA expression profiles among conventional freezing sperm, droplet vitrification freezing sperm and fresh human sperm...
May 10, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38727211/seminal-plasma-s100a8-a9-as-a-potential-biomarker-of-genital-tract-inflammation
#10
JOURNAL ARTICLE
Qiu-Zi Shen, Yong-Feng Wang, Yi-Wei Fang, Yuan-Yao Chen, Li-Ting He, Yuan Zhang, Guo-Tao Liu, Kai Zhao, Chun-Yan Liu, Zun-Pan Fan, Hui-Ping Zhang
Infections and inflammatory reactions in the male genital tract are the leading causes of male infertility with a prevalence of 6%-10%, primarily affecting testicular and epididymal function and ultimately compromising sperm quality. However, most infertile patients with genital infection/inflammation are asymptomatic and easily overlooked. Traditional indicators, including white blood cells, elastase, and other components in semen, can reflect inflammation of the genital tract, but there is still a lack of a uniform standard method of detection...
May 7, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38738954/navigating-the-evolving-diagnostic-and-therapeutic-landscape-of-low-and-intermediate-risk-prostate-cancer
#11
JOURNAL ARTICLE
Fabio Zattoni, Fabio Matrone, Roberto Bortolus, Gianluca Giannarini
In this nonsystematic review of the literature, we explored the changing landscape of detection and treatment of low- and intermediate-risk prostate cancer (PCa). Through emphasizing improved cancer assessment with histology classification and genomics, we investigated key developments in PCa detection and risk stratification. The pivotal role of prostate magnetic resonance imaging (MRI) in the novel diagnostic pathway is examined, alongside the benefits and drawbacks of MRI-targeted biopsies for detection and tumor characterization...
May 3, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38722110/altered-regional-brain-activity-and-functional-connectivity-in-primary-intravaginal-anejaculation-patients-revealed-by-resting-state-fmri
#12
JOURNAL ARTICLE
Qing-Qiang Gao, Jian-Huai Chen, Jia-Ming Lu, Bin Wang, You-Feng Han, Song-Zhan Gao, Jie Yang, Yu-Tian Dai
Ejaculation is regulated by the central nervous system. However, the central pathophysiology of primary intravaginal anejaculation (PIAJ) is unclear. The present study aimed to examine the changes in regional brain activity and functional connectivity underlying PIAJ. A total of 20 PIAJ patients and 16 healthy controls (HCs) were enrolled from September 2020 to September 2022 in the Department of Andrology, Nanjing Drum Tower Hospital (Nanjing, China). Magnetic resonance imaging data were acquired from all participants and then were preprocessed...
May 3, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38727256/high-intensity-focused-ultrasound-strategies-for-treating-prostate-cancer
#13
JOURNAL ARTICLE
Xiaobo Wu, Yupeng Wu, Chi-Fai Ng, Chi-Hang Yee, Peter Ka-Fung Chiu
Prostate cancer (PCa) is a significant health concern globally, necessitating effective treatment options. Typical treatment methods for early stage, particularly localized PCa, encompass radical procedures, such as radical prostatectomy (RP) and radiotherapy (RT), and nonradical focal therapy (FT). FT is a focused approach mainly used for treating small lesions limited to a specific zone of the prostate. Its objective is to achieve cancer control when minimizing damage to benign tissue. High-intensity focused ultrasound (HIFU) is one of the most used modalities in FT for the management of PCa...
April 26, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38727255/commentary-on-relationship-between-dietary-niacin-intake-and-erectile-dysfunction-a-population-based-study
#14
JOURNAL ARTICLE
Eric Chung
No abstract text is available yet for this article.
April 26, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38657119/single-cell-analysis-revealing-the-metabolic-landscape-of-prostate-cancer
#15
JOURNAL ARTICLE
Jing Wang, He-Kang Ding, Han-Jiang Xu, De-Kai Hu, William Hankey, Li Chen, Jun Xiao, Chao-Zhao Liang, Bing Zhao, Ling-Fan Xu
Tumor metabolic reprogramming is a hallmark of cancer development, and targeting metabolic vulnerabilities has been proven to be an effective approach for castration-resistant prostate cancer (CRPC) treatment. Nevertheless, treatment failure inevitably occurs, largely due to cellular heterogeneity, which cannot be deciphered by traditional bulk sequencing techniques. By employing computational pipelines for single-cell RNA sequencing, we demonstrated that epithelial cells within the prostate are more metabolically active and plastic than stromal cells...
April 23, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38639721/male-reproductive-function-before-and-after-the-adjustment-of-the-covid-19-prevention-policy-a-multicenter-study-in-china
#16
JOURNAL ARTICLE
Jian-Zheng Li, Han Wu, Li Wang, Yun-Shan Wang, Feng Kong, Long-Qiao Cao, Ming Liang, Xiong Wang, Ming-Zhen Yuan
At the end of 2022, the adjustment of the coronavirus disease 2019 (COVID-19) pandemic control policy in China resulted in a large-scale increase in public infection. To compare the fertility parameters of male patients before and after the adjustments of the COVID-19 pandemic control policy in China, we collected data on patients' medical histories and laboratory examinations on their first visits between June 2022 and March 2023 in five different hospitals. Data were divided into five groups according to the timeline of the policy adjustment...
April 19, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38639716/orchiopexy-one-procedure-two-diagnoses-different-male-infertility-outcomes
#17
JOURNAL ARTICLE
Nitza Heiman Newman, Idan Farber, Eitan Lunenfeld, Atif Zeadna, Iris Har Vardi, Zaki Assi
Infertility, affecting one in six couples, is often related to the male partner's congenital and/or environmental conditions or complications postsurgery. This retrospective study examines the link between orchiopexy for undescended testicles (UDT) and testicular torsion (TT) in childhood and adult fertility as assessed through sperm analysis. The study involved the analysis of semen samples from 7743 patients collected at Soroka University Medical Center (Beer Sheva, Israel) between January 2009 and December 2017...
April 19, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38639715/impact-of-carbimazole-combined-with-vitamin-e-on-testicular-injury-induced-by-experimental-hyperthyroidism-in-adult-albino-rats-oxidative-inflammatory-apoptotic-pathways
#18
JOURNAL ARTICLE
Ramadan S Hussein, Moustafa M Eyada, Rashad M Mostafa, Samah M Elaidy, Shereen H Elsayed, Hany M Saad
Thyroid hormones play essential roles in spermatogenesis, but their effects on infertile males remain poorly understood. This study aimed to evaluate the impact of combining carbimazole (CBZ) with vitamin E (VE) on testicular injury induced by experimental hyperthyroidism in adult albino rats, focusing on oxidative, inflammatory, and apoptotic pathways. In this experimental study, 64 adult male albino Wistar rats were divided into eight groups: Group I (control-untreated), Group II (CBZ-control), Group III (VE-control), Group IV (CBZ + VE-control), Group V (levothyroxine-induced testicular injury), Group VI (levothyroxine + CBZ-treated), Group VII (levothyroxine + VE-treated), and Group VIII (levothyroxine + CBZ + VE-treated)...
April 19, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38624201/transrectal-versus-transperineal-prostate-biopsy-for-cancer-detection-in-patients-with-gray-zone-prostate-specific-antigen-a-multicenter-real-world-study
#19
JOURNAL ARTICLE
Jun-Xiao Liu, Ze-Yuan Wang, Shao-Xi Niu, Xiao-Yong Sai, Xu Zhang, Xue-Pei Zhang, Xin Ma
Knowledge about the effect of different prostate biopsy approaches on the prostate cancer detection rate (CDR) in patients with gray-zone prostate-specific antigen (PSA) is limited. We performed this study to compare the CDR among patients who underwent different biopsy approaches and had rising PSA levels in the gray zone. Two hundred and twenty-two patients who underwent transrectal prostate biopsy (TRB) and 216 patients who underwent transperineal prostate biopsy (TPB) between June 2016 and September 2022 were reviewed in this study...
April 16, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38624205/machine-learning-approach-to-assess-the-association-between-anthropometric-metabolic-and-nutritional-status-and-semen-parameters
#20
JOURNAL ARTICLE
Guillaume Bachelot, Antonin Lamaziere, Sebastien Czernichow, Celine Faure, Chrystelle Racine, Rachel Levy, Charlotte Dupont
Many lifestyle factors, such as nutritional imbalance leading to obesity, metabolic disorders, and nutritional deficiency, have been identified as potential risk factors for male infertility. The aim of this study was to evaluate the relationship between semen parameters and anthropometric, metabolic and nutritional parameters. Relationship was first assessed individually, then after the application of a previously constructed and validated machine learning score that allows their combination. Anthropometric, metabolic, antioxidant, micronutrient, and sperm parameters from 75 men suffering from idiopathic infertility from four infertility centers in France (Jean-Verdier ART Center Hospital, Bondy; North Hospital ART Center, Saint-Étienne; Navarre Polyclinic ART Center, Pau; and Cochin Hospital ART Center, Paris) between September 2009 and December 2013 were collected...
April 12, 2024: Asian Journal of Andrology
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