David Kingsmore, Richard D White, Gaspar Mestres, Mike Stephens, Francis Calder, Georgios Papadakis, Emma Aitken, Andrew Jackson, Nick Inston, Rob G Jones, Colin Geddes, Karen Stevenson, Laszlo Szabo, Peter Thomson, Callum Stove, Ram Kasthuri, Ben Edgar, Matteo Tozzi, Marco Franchin, Rajesh Sivaprakasam, Nikolaos Karydis
Although randomised controlled trials (RCT) are considered the optimal form of evidence, there are relatively few in surgery. Surgical RCT are particularly likely to be discontinued with poor recruitment cited as a leading reason. Surgical RCT present challenges over and above those seen in drug trials as the treatment under study may vary between procedures, between surgeons in one unit, and between units in multi-centred RCT. The most contentious and debated area of vascular access remains the role of arteriovenous grafts, and thus the quality of the data that is used to support opinions, guidelines and recommendations is critical...
March 11, 2023: Journal of Vascular Access