Samantha A Banks, Julio C Sartori Valinotti, Ronald S Go, Jithma P Abeykoon, Gaurav Goyal, Jason R Young, Matthew J Koster, Robert Vassallo, Jay H Ryu, Caroline J Davidge-Pitts, Aishwarya Ravindran, N Nora Bennani, Mithun V Shah, Karen L Rech, W Oliver Tobin
PURPOSE OF REVIEW: Histiocytic disorders, including Erdheim-Chester disease (ECD), Langerhans cell histiocytosis (LCH), and Rosai-Dorfman disease (RDD), are rare neoplasms that may present with a spectrum of neurologic involvement. Diagnostic delay is common due to heterogeneity in presentation and challenging pathology. RECENT FINDINGS: Recent advances in the treatment of these diseases targeted towards mutations in the MAP kinase pathway have led to an improved prognosis in these patients with neurologic involvement...
May 20, 2023: Current Neurology and Neuroscience Reports