Thiago Camelo Mourão, Stephania Martins Bezerra, Victor Espinheira Santos, Eder Silveira Brazão, Walter Henriques da Costa, Stênio de Cássio Zequi
PURPOSE OF REVIEW: The physiological aspects of renin-angiotensin system (RAS) components are described in this review. Additionally, we present the main results of studies that could indicate an association between alterations in these components and cancer, particularly renal cell carcinoma (RCC). RECENT FINDINGS: The RAS undergoes a series of homeostatic and modulatory processes that extend to hypertrophy, hyperplasia, fibrosis, and remodeling, as well as angiogenesis, pro-inflammatory responses, cell differentiation, stem cell programming, and hematopoiesis...
July 2023: Current Urology Reports