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Journals
HPB : the Official Journal of ...
HPB : the Official Journal of the International Hepato Pancreato Biliary Association
#21
JOURNAL ARTICLE
Roxane D Staiger, Tarun Mehra, Sarah R Haile, Anja Domenghino, Christoph Kümmerli, Fariba Abbassi, Damian Kozbur, Philipp Dutkowski, Milo A Puhan, Pierre-Alain Clavien
BACKGROUND: Machine learning (ML) has been successfully implemented for classification tasks (e.g., cancer diagnosis). ML performance for more challenging predictions is largely unexplored. This study's objective was to compare machine learning vs. expert-informed predictions for surgical outcome in patients undergoing major liver surgery. METHODS: Single tertiary center data on preoperative parameters and postoperative complications for elective hepatic surgery patients were included (2008-2021)...
February 13, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#22
LETTER
Lorenzo Loffredo, Enrico Maggio, Anna Rita Vestri, Arianna Di Rocco, Pasquale Pignatelli, Francesco Violi
No abstract text is available yet for this article.
February 13, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#23
REVIEW
Francis P Robertson, Andrew Cameron, Harry V M Spiers, Nejo Joseph, Ellie Taylor, Bathiya Ratnayake, Nigel B Jamieson, Sanjay Pandanaboyana
BACKGROUND: Pancreatic Ductal Adenocarcinoma (PDAC) patients exhibit varied responses to multimodal therapy. RNA gene sequencing has unravelled distinct tumour biology subtypes, forming the focus of this review exploring its impact on survival outcomes. METHODS: A systematic search across PubMed, Medline, Embase, and CINAHL databases targeted studies assessing long-term overall and disease-free survival in PDAC patients with molecular subtyping. RESULTS: Fifteen studies including 2731 patients were identified...
February 10, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#24
JOURNAL ARTICLE
Pietro Addeo, Pierre de Marini, Gerlinde Averous, Arnaud Trog, Pierre de Mathelin, Stefano Gussago, Laura Fiore, Lucas Geyer, Vincent Noblet, Philippe Bachellier
BACKGROUND: High acinar pancreatic contents are associated with a higher rate of postpancreatectomy acute pancreatitis and pancreatic fistula formation (POPF). Predicting acinar contents preoperatively might identify those at high risk of developing postoperative complications. METHODS: A multivariable analysis was performed to identify radiological factors associated with high pancreatic acinar content at histology in patients undergoing pancreaticoduodenectomy...
February 9, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#25
REVIEW
Zaiba S Dawood, Zachary J Brown, Laura Alaimo, Henrique A Lima, Chanza Shaikh, Erryk S Katayama, Muhammad M Munir, Zorays Moazzam, Yutaka Endo, Selamawit Woldesenbet, Timothy M Pawlik
BACKGROUND: The efficacy of immune checkpoint inhibitors (ICIs) combined with tyrosine kinase inhibitors (TKIs), trans-arterial chemoembolization (TACE), and radiotherapy to treat hepatocellular carcinoma (HCC) has not been well-defined. We performed a meta-analysis to characterize tumor response and survival associated with multimodal treatment of HCC. METHODS: PubMed, Embase, Medline, Scopus, and CINAHL databases were searched (1990-2022). Random-effect meta-analysis was conducted to compare efficacy of treatment modalities...
February 9, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#26
JOURNAL ARTICLE
Gregory Hooks, Han Lu, Anne Eaton, Guru Trikudanathan, Elissa Downs, Martin L Freeman, Sarah J Schwarzenberg, Timothy L Pruett, Srinath Chinnakotla, Karthik Ramanathan, Gregory J Beilman, Melena D Bellin
BACKGROUND: Total pancreatectomy with islet autotransplant (TPIAT) can improve quality of life for individuals with pancreatitis but creates health risks including diabetes, exocrine insufficiency, altered intestinal anatomy and function, and asplenia. METHODS: We studied survival and causes of death for 693 patients who underwent TPIAT between 2001 and 2020, using the National Death Index with medical records to ascertain survival after TPIAT, causes of mortality, and risk factors for death...
February 9, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#27
LETTER
Sree Subramaniyan S, Bishal Pal, Sowmiya Velusamy, Mannoj K Shanmugam, Debasis Naik, Shnamugam Dasarathan, Vishnu Prasad Nelamangala Ramakrishnaiah
No abstract text is available yet for this article.
February 9, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#28
JOURNAL ARTICLE
Wen-Qiang Wang, Jian Li, Xing Lv, Jin-Lin Wang, Er-Lei Zhang, Bin-Hao Zhang, Zhen-Yu Xiao, Bin-Yong Liang, Zhi-Yong Huang
BACKGROUND: Anatomical sectionectomy based on Takasaki's segmentation has shown advantages in hepatocellular carcinoma. However, whether this approach improves the survival of intrahepatic cholangiocarcinoma (ICC) remains unknown. METHODS: A series of 248 consecutive patients with solitary ICCs who underwent hepatectomy were studied retrospectively. The patients were classified into the groups of anatomical sectionectomy based on Takasaki's segmentation (TS group) and non-Takasaki's hepatectomy (NTH group)...
February 1, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#29
JOURNAL ARTICLE
Syed S Raza, Hala Khan, Shahab Hajibandeh, Shahin Hajibandeh, David Bartlett, Nikolaos Chatzizacharias, Keith Roberts, Ravi Marudanayagam, Robert P Sutcliffe
BACKGROUND: To investigate the relationship between preoperative Carbohydrate Antigen19-9(CA19-9)and pancreatic cancer occult metastasis. METHODS: Systematic search of MEDLINE, CENTRAL, Web of Science and bibliographic reference lists were conducted. All comparative observational studies investigating the predictive ability of preoperative CA 19-9 in patients with pancreatic cancer were considered. Mean CA-19-9 value in the pancreatic cancer patients with and without metastasis were evaluated...
February 1, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#30
JOURNAL ARTICLE
Nejo Joseph, Francis Robertson, James Lucocq, Rupaly Pande, Sarah Powell-Brett, Kate Swainston, Linda Sharp, Catherine Exley, Keith Roberts, Sanjay Pandanaboyana
BACKGROUND: The temporal evolution of HRQoL and the importance of other PROs to patients, following resection for pancreatic and peripancreatic malignancy remains unexplored. METHODS: Patients undergoing pancreatic resection between 2021 and 2022 were enrolled from 2 UK HPB centres. Patients completed the EORTC QLQ-C30, QLQ-PAN26 tools and rated 56 PROs preoperatively (T1), at discharge (T2), 6-weeks (T3), 3-months (T4) and 6-months (T5) postoperatively. ANOVA followed by post-hoc analysis was used to examine patterns in HRQoL through time...
February 1, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#31
JOURNAL ARTICLE
Roberto Montalti, Gianluca Cassese, Ahmed Zidan, Gianluca Rompianesi, Mariano Cesare Giglio, Silvia Campanile, Lorenza Arena, Marco Maione, Roberto I Troisi
BACKGROUND: Minimally Invasive thermal ablation (MITA) of liver tumors is a commonly performed procedure, alone or in combination with liver resection. Despite being a first-option strategy for small lesions, it is technically demanding, and many concerns still exist about local disease control. METHODS: Consecutive patients undergoing MITA from 1-2019 to 12-2022 were retrospectively enrolled. Risk factors of local recurrence were investigated through univariate and multivariable cox regression analysis...
February 1, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#32
JOURNAL ARTICLE
Giampaolo Perri, Ajith K Siriwardena, Stefan Gilg, Ernesto Sparrelid
BACKGROUND: There are no established training pathways for hepato-pancreato-biliary (HPB) surgery in Europe. This study aims to overview the current status of fellowship training from both fellows' and institutions' perspectives. METHODS: A web-based snapshot survey was distributed to all members of the European-African Hepato-Pancreato-Biliary Association (E-AHPBA) to reach for former fellows and program directors of European HPB surgery fellowships held between 2013 and 2023...
February 1, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#33
JOURNAL ARTICLE
Babette I Kuiper, Mohammad Abu Hilal, Luca A Aldrighetti, Bergthor Björnsson, Mathieu D'Hondt, Cristina Dopazo, Åsmund A Fretland, Helena Isoniemi, J Philip Jonas, Geert Kazemier, Mickael Lesurtel, John Primrose, Andreas A Schnitzbauer, Tineke Buffart, Birgit Gruenberger, Rutger-Jan Swijnenburg, Thomas Gruenberger
BACKGROUND: There is a lack of consensus on the definition of upfront resectability and use of perioperative systemic therapy for colorectal liver metastases (CRLM). This survey aimed to summarize the current treatment strategies for upfront resectable CRLM throughout Europe. METHODS: A survey was sent to all members of the European-African Hepato-Pancreato-Biliary Association to gain insight into the current views on resectability and the use of systemic therapy for upfront resectable CRLM...
January 29, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#34
JOURNAL ARTICLE
Noor J Sissingh, Hester C Timmerhuis, Jesse V Groen, Mike J P de Jong, Marc G Besselink, Bas Boekestijn, Thomas L Bollen, Bert A Bonsing, Stefan A W Bouwense, Wouter L Hazen, Frederikus A Klok, Hjalmar C van Santvoort, Casper H J van Eijck, Robert C Verdonk, J Sven D Mieog, Jeanin E van Hooft
BACKGROUND: Treatment guidelines for splanchnic vein thrombosis in necrotizing pancreatitis are lacking due to insufficient data on the full clinical spectrum. METHODS: We performed a post-hoc analysis of a nationwide prospective necrotizing pancreatitis cohort. Multivariable analyses were used to identify risk factors and compare the clinical course of patients with and without SVT. RESULTS: SVT was detected in 97 of the 432 included patients (22%) (median onset: 4 days)...
January 29, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#35
JOURNAL ARTICLE
Sophie Laroche, Chetana Lim, Claire Goumard, Michel Rayar, Daniel Cherqui, Laurence Chiche, Louise Barbier, Ephrem Salamé, Jean-Yves Mabrut, Mickael Lesurtel, Stéphanie Truant, Emmanuel Boleslawski, Fabrice Muscari, Christian Hobeika, Mircea Chirica, Emmanuel Buc, Jean Hardwigsen, Astrid Herrero, Francis Navarro, François Faitot, Philippe Bachellier, Jean-Marc Regimbeau, Alexis Laurent, David Fuks, Olivier Soubrane, Daniel Azoulay, Eric Vibert, Olivier Scatton
BACKGROUND: There are no data to evaluate the difference in populations and impact of centers with liver transplant programs in performing laparoscopic liver resection (LLR). METHODS: This was a multicenter study including patients undergoing LLR for benign and malignant tumors at 27 French centers from 1996 to 2018. The main outcomes were postoperative severe morbidity and mortality. RESULTS: A total of 3154 patients were included, and 14 centers were classified as transplant centers (N = 2167 patients, 68...
January 25, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#36
LETTER
Alejandra García-Botella, Paz Martín, Ramiro Méndez, Luis Ortega, Jose Méndez, Javier Sastre, Luis Diez-Valladares, Antonio J Torres
No abstract text is available yet for this article.
January 22, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#37
JOURNAL ARTICLE
Kristen E Rhodin, Stacy Goins, Ryan Kramer, Austin M Eckhoff, Garth Herbert, Kevin N Shah, Peter J Allen, Daniel P Nussbaum, Dan G Blazer, Sabino Zani, Michael E Lidsky
BACKGROUND: Radical cholecystectomy is recommended for T1B and greater gallbladder cancer, however, there are conflicting reports on the utility of extended resection for T1B disease. Herein, we characterize outcomes following simple and radical cholecystectomy for pathologic stage T1B gallbladder cancer. METHODS: The National Cancer Database (NCDB) was queried for patients with pathologic T1B gallbladder cancer diagnosed from 2004 to 2018. Patients were stratified by surgical management...
April 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#38
REVIEW
Marcus Yeow, Khi Y Fong, Joseph J Zhao, Alvin Y Hui Tan, Ye X Koh, Juinn H Kam, Brian K P Goh, Timothy M Pawlik, Tousif Kabir
BACKGROUND: The aim of this study was to perform a systematic review and meta-analysis to investigate the impact of lymph node dissection (LND) on outcomes following resection of intrahepatic cholangiocarcinoma (ICC). METHODS: PubMed, EMBASE, and Cochrane were searched from inception to 30th January 2023 for studies that compared LND with no LND (NLND) among patients with ICC. To limit the effect of unbalanced covariates, only studies that utilized propensity score-based methods were included...
February 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#39
JOURNAL ARTICLE
Núria Lluís, Shunsuke Onoe, Mario Serradilla-Martín, Mar Achalandabaso, Takashi Mizuno, François Jehaes, Bobby V M Dasari, Sara Mambrilla-Herrero, Ernesto Sparrelid, Anita Balakrishnan, Frederik J H Hoogwater, María J Amaral, Bodil Andersson, Frederik Berrevoet, Alexandre Doussot, Víctor López-López, Olivier Detry, Carlos Domingo-Del Pozo, Nikolaos Machairas, Damján Pekli, Cándido F Alcázar-López, Horacio Asbun, Bergthor Björnsson, Thalis Christophides, Alberto Díez-Caballero, David Francart, Colin B Noel, Donzília Sousa-Silva, Enrique Toledo-Martínez, George N Tzimas, Sheraz Yaqub, Junpei Yamaguchi, Safi Dokmak, Mikel Prieto-Calvo, Melroy A D'Souza, Harry V M Spiers, Marius C van den Heuvel, Ramón Charco, Mickaël Lesurtel, Tomoki Ebata, José M Ramia
BACKGROUND: Intraductal papillary neoplasm of the bile ducts (IPNB) is a rare disease in Western countries. The aim of this study was to compare tumor characteristics, management strategies, and outcomes between Western and Eastern patients who underwent surgical resection for IPNB. METHODS: A multi-institutional retrospective series of patients with IPNB undergoing surgery between January 2010 and December 2020 was gathered under the auspices of the European-African Hepato-Pancreato-Biliary Association (E-AHPBA), and at Nagoya University Hospital, Japan...
January 19, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#40
JOURNAL ARTICLE
Ahmed R Badawy, Ho-Seong Han, Tamer M El-Mahdy, Hossam Eldeen M Soliman, Mohammad H Abo-Ryia, Osama H Elkhadrawy
OBJECTIVE: To determine the impacts and outcomes of laparoscopic anatomic liver resection (LAR) and laparoscopic nonanatomic resection (LNAR) in patients with large hepatocellular carcinoma (HCC) in the right lobe of the liver. BACKGROUND: There are few comparative studies of LAR and LNAR for large HCC. METHOD: Three hundred thirty-seven patients underwent liver resection for large HCC (≥5 cm) at Seoul National University Bundang Hospital, Seoul, Korea, between January 2004 and December 2022...
January 18, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
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