journal
https://read.qxmd.com/read/37657111/editorial-four-level-anterior-cervical-discectomy-and-fusion-a-cautionary-tale
#1
EDITORIAL
Mohamad Bydon, Erica F Bisson, Andrew K Chan, Praveen V Mummaneni
No abstract text is available yet for this article.
September 2023: Neurosurgical Focus
https://read.qxmd.com/read/37657110/does-the-presence-of-cervical-deformity-in-patients-with-baseline-mild-myelopathy-increase-operative-urgency-in-adult-cervical-spinal-surgery-a-retrospective-analysis
#2
JOURNAL ARTICLE
Peter S Tretiakov, Emmanuel Budis, Pooja Dave, Jamshaid Mir, Matthew Galetta, Nathan Lorentz, M Burhan Janjua, Pawel P Jankowski, Peter G Passias
OBJECTIVE: The objective of this study was to assess whether delaying surgical management of cervical deformity (CD) in patients with concomitant mild myelopathy increases the risk of suboptimal outcomes. METHODS: Patients aged ≥ 18 years who had a baseline diagnosis of mild myelopathy with baseline and up to 2 years of postoperative data were assessed. Patients were categorized as having CD (CD+) or not (CD-) at baseline. Patients with symptoms of myelopathy for more than 1 year after the initial visit prior to surgery were considered delayed...
September 2023: Neurosurgical Focus
https://read.qxmd.com/read/37657109/pseudarthrosis-after-four-level-anterior-cervical-discectomy-and-fusion-without-posterior-fixation
#3
JOURNAL ARTICLE
Michael D White, S Harrison Farber, Mark A Pacult, Corey T Walker, James J Zhou, Juan S Uribe, Steve Chang, Udaya K Kakarla, Jay D Turner
OBJECTIVE: Fusion rates and long-term outcomes are well established for anterior cervical discectomy and fusion (ACDF) of 3 levels or fewer, but there is a paucity of similar data on 4-level fusions. The authors evaluated long-term fusion rates and clinical outcomes after 4-level ACDF without supplemental posterior instrumentation. METHODS: The authors retrospectively reviewed patients who underwent 4-level ACDF at a single institution with at least 1-year of radiological follow-up...
September 2023: Neurosurgical Focus
https://read.qxmd.com/read/37657108/does-hinge-sidedness-influence-laterality-of-c5-palsy-after-expansile-open-door-cervical-laminoplasty
#4
JOURNAL ARTICLE
David J Levi, G Damian Brusko, Allan D Levi, Michael Y Wang
OBJECTIVE: Cervical expansile open-door laminoplasties (EOLPs) have an open side and a hinge side, with the open side being bridged by grafts or miniplates. The authors explored the possibility that the open-door side might have a greater incidence of C5 palsy due to a greater stretch of the ipsilateral C5 nerve root. METHODS: This study was a retrospective review of prospectively collected data over a period of 25 years specifically assessing surgical complications...
September 2023: Neurosurgical Focus
https://read.qxmd.com/read/37657107/feasibility-of-postoperative-diffusion-weighted-imaging-to-assess-representations-of-spinal-cord-microstructure-in-cervical-spondylotic-myelopathy
#5
JOURNAL ARTICLE
Justin K Zhang, Saad Javeed, Jacob K Greenberg, Kathleen S Botterbush, Braeden Benedict, Jacob Blum, Christopher F Dibble, Peng Sun, Sheng-Kwei Song, Wilson Z Ray
OBJECTIVE: Diffusion basis spectrum imaging (DBSI) has shown promise in evaluating cervical spinal cord structural changes in patients with cervical spondylotic myelopathy (CSM). DBSI may also be valuable in the postoperative setting by serially tracking spinal cord microstructural changes following decompressive cervical spine surgery. Currently, there is a paucity of studies investigating this topic, likely because of challenges in resolving signal distortions from spinal instrumentation...
September 2023: Neurosurgical Focus
https://read.qxmd.com/read/37657106/introduction-toward-a-contemporaneous-understanding-of-cervical-spondylotic-myelopathy
#6
JOURNAL ARTICLE
Andrew K Chan, Erica F Bisson, Mohamad Bydon, Praveen V Mummaneni
No abstract text is available yet for this article.
September 2023: Neurosurgical Focus
https://read.qxmd.com/read/37657105/letter-to-the-editor-machine-learning-based-prediction-models-in-neurosurgery
#7
LETTER
Karl J Habashy, Víctor A Arrieta, James Feghali
No abstract text is available yet for this article.
September 2023: Neurosurgical Focus
https://read.qxmd.com/read/37657104/surgical-strategies-for-the-treatment-of-deformity-associated-cervical-spondylotic-stretch-myelopathy-a-case-series-with-technically-nuanced-illustrative-operative-videos
#8
JOURNAL ARTICLE
Wilson A M Fisher, Olivia E Gilbert, Cheerag Upadhyaya, Michael Galgano
OBJECTIVE: The aim of this study was to elucidate the vital role of anterior-only osteotomies for rigid cervical kyphosis causing stretch myelopathy by using illustrative cases and high-definition intraoperative videos. METHODS: The authors describe 4 select patients who underwent anterior-only osteotomies within a 2-year time frame and demonstrate the nuances of each case with unique operative videos. RESULTS: Outcomes for each of the cases demonstrated marked improvement in cervical spine alignment relative to preoperative conditions...
September 2023: Neurosurgical Focus
https://read.qxmd.com/read/37657103/three-level-acdf-versus-3-level-laminectomy-and-fusion-are-there-differences-in-outcomes-an-analysis-of-the-quality-outcomes-database-cervical-spondylotic-myelopathy-cohort
#9
JOURNAL ARTICLE
Vardhaan S Ambati, Mohamed Macki, Andrew K Chan, Giorgos D Michalopoulos, Vivian P Le, Alysha B Jamieson, Dean Chou, Christopher I Shaffrey, Oren N Gottfried, Erica F Bisson, Anthony L Asher, Domagoj Coric, Eric A Potts, Kevin T Foley, Michael Y Wang, Kai-Ming Fu, Michael S Virk, John J Knightly, Scott Meyer, Paul Park, Cheerag Upadhyaya, Mark E Shaffrey, Avery L Buchholz, Luis M Tumialán, Jay D Turner, Brandon A Sherrod, Regis W Haid, Mohamad Bydon, Praveen V Mummaneni
OBJECTIVE: The authors sought to compare 3-level anterior with posterior fusion surgical procedures for the treatment of multilevel cervical spondylotic myelopathy (CSM). METHODS: The authors analyzed prospective data from the 14 highest enrolling sites of the Quality Outcomes Database CSM module. They compared 3-level anterior cervical discectomy and fusion (ACDF) and posterior cervical laminectomy and fusion (PCF) surgical procedures, excluding surgical procedures crossing the cervicothoracic junction...
September 2023: Neurosurgical Focus
https://read.qxmd.com/read/37657102/cervical-disc-arthroplasty-for-magnetic-resonance-evident-cervical-spondylotic-myelopathy-comparison-with-anterior-cervical-discectomy-and-fusion
#10
JOURNAL ARTICLE
Tsai-Tzu Ko, Ching-Lan Wu, Hsuan-Kan Chang, Chih-Chang Chang, Yi-Hsuan Kuo, Mei-Yin Yeh, Chao-Hung Kuo, Chin-Chu Ko, Li-Yu Fay, Tsung-Hsi Tu, Wen-Cheng Huang, Jau-Ching Wu
OBJECTIVE: Anterior cervical discectomy and fusion (ACDF) is a standard surgical approach for cervical spondylotic myelopathy (CSM) caused by disc herniations. Although cervical disc arthroplasty (CDA) has become, in the past decade, a viable alternative to ACDF in selected patients, the differences among patients with CSM treated with CDA and ACDF remain elusive. The effectiveness of motion preservation devices in CSM is also unclear. METHODS: Adult patients who underwent 1- or 2-level CDA or ACDF between 2007 and 2021 were retrospectively reviewed...
September 2023: Neurosurgical Focus
https://read.qxmd.com/read/37657101/the-effect-of-myelopathic-symptoms-on-hospital-costs-length-of-stay-and-discharge-location-in-anterior-cervical-discectomy-and-fusion
#11
JOURNAL ARTICLE
Ken Porche, Sasha Vaziri, Alan Stein, Omar Awan, Paul S Kubilis, Paul Lipori, Daniel J Hoh, Adam Polifka, W Christopher Fox
OBJECTIVE: Cervical spondylotic myelopathy (CSM) is a common clinical degenerative disease treated with anterior cervical discectomy and fusion (ACDF), which seriously impacts quality of life and causes severe disability. The objective of the study was to determine the effect of different characteristics of the neurological deficit found in myelopathic patients undergoing ACDFs on hospital cost, length of stay (LOS), and discharge location. METHODS: This is a retrospective review of ACDF cases performed at a single institution by multiple surgeons from 2011 to 2017...
September 2023: Neurosurgical Focus
https://read.qxmd.com/read/37527686/erratum-introduction-machine-learning-in-neurosurgery-transitioning-to-a-new-era-of-contemporary-medicine
#12
JOURNAL ARTICLE
Gillian Shasby
No abstract text is available yet for this article.
August 2023: Neurosurgical Focus
https://read.qxmd.com/read/37527684/letter-to-the-editor-central-or-axial-atlantoaxial-dislocation
#13
LETTER
Andrei Fernandes Joaquim, Jefferson W Daniel, Roger S Brock, Fernando R Dantas, Eloy Rusafa Neto, Jerônimo B Milano, Alécio C E Santos Barcelos, Eduardo de Freitas Bertolini, Franz J Onishi
No abstract text is available yet for this article.
August 2023: Neurosurgical Focus
https://read.qxmd.com/read/37527683/surgical-management-of-brain-metastasis-from-ovarian-cancer-a-systematic-review-and-case-series
#14
JOURNAL ARTICLE
Meredith C Costello, Greeshma Venigalla, Martín A Merenzon, Shovan Bhatia, Alexis A Morell, Lekhaj Daggubati, Evan Luther, Ashish H Shah, Ricardo J Komotar, Michael E Ivan
OBJECTIVE: Ovarian cancer is a rare origin of brain metastasis (BM), with an incidence of only 1%-3%. Consequently, the literature is sparse, and no treatment consensus guideline is available for ovarian BM. The authors conducted a systematic review of ovarian BM and performed a combined pooled cohort survival analysis with their case series. METHODS: A systematic review of PubMed, Scopus, and Web of Science consistent with PRISMA guidelines along with an institutional retrospective chart review was conducted...
August 2023: Neurosurgical Focus
https://read.qxmd.com/read/37527682/genomic-alterations-associated-with-rapid-progression-of-brain-metastases
#15
JOURNAL ARTICLE
Amalie S V Uggerly, Daniel D Cummins, Minh P Nguyen, Satvir Saggi, Ezequiel Goldschmidt, Edward F Chang, Michael W McDermott, Mitchel S Berger, Philip V Theodosopoulos, Shawn L Hervey-Jumper, Mariza Daras, Manish K Aghi, Ramin A Morshed
OBJECTIVE: The aim of this study was to investigate associations between genomic alterations in resected brain metastases and rapid local and distant CNS recurrence identified at the time of postoperative adjuvant radiosurgery. METHODS: This was a retrospective study on patients who underwent resection of intracranial brain metastases. Next-generation sequencing of more than 500 coding genes was performed on brain metastasis specimens. Postoperative and preradiosurgery MR images were compared to identify rapid recurrence...
August 2023: Neurosurgical Focus
https://read.qxmd.com/read/37527681/mr-guided-focused-ultrasound-induced-blood-brain-barrier-opening-for-brain-metastasis-a-review
#16
REVIEW
Giovanni Grasso, Fabio Torregrossa, Manfredi Noto, Eleonora Bruno, Paola Feraco, Felice Buscemi, Tommaso Vincenzo Bartolotta, Cesare Gagliardo
Although the therapeutic armamentarium for brain metastases (BMs) has been expanded from innovative surgical techniques and radiotherapy to include targeted therapies and immunotherapy, the prognosis of BMs remains poor. Despite the proven efficacy of numerous compounds in preclinical studies, the limited penetration of promising therapeutic agents across the blood-brain barrier (BBB) remains an unaddressed issue. Recently, low-intensity magnetic resonance-guided focused ultrasound (MRgFUS) in combination with microbubbles has been shown to overcome vascular and cellular transport barriers in the brain and tumor microenvironment, resulting in increased drug diffusion and preliminary effective results...
August 2023: Neurosurgical Focus
https://read.qxmd.com/read/37527680/the-role-of-the-dura-mater-in-cerebral-metastases
#17
REVIEW
Francesca M Cozzi, Leonel Ampie, Maxwell T Laws, Desmond A Brown
OBJECTIVE: The objective of this review was to describe the immunological changes that take place in the dura mater in response to metastatic disease that seeds the CNS. The authors hypothesized that the dura's anatomy and resident immune cell population play a role in enabling metastasis to the brain and leptomeninges. METHODS: An extensive literature search was conducted to identify evidence that supports the dura's participation in metastasis to the CNS. The authors' hypothesis was informed by a recent upsurge in studies that have investigated the dura's role in metastatic development, CNS infections, and autoimmunity...
August 2023: Neurosurgical Focus
https://read.qxmd.com/read/37527679/treatment-outcome-of-metastasis-to-the-pituitary-gland-a-case-series-of-21-patients-with-pathological-diagnosis
#18
JOURNAL ARTICLE
Sukwoo Hong, John L Atkinson, Dana Erickson, Sani H Kizilbash, Jason T Little, David M Routman, Jamie J Van Gompel
OBJECTIVE: The aim of this study was to report the treatment course of histologically confirmed metastases to the pituitary gland (pituitary metastasis). METHODS: The Mayo data explorer was used to find patients with pituitary metastasis. Twenty-one patients were identified between the years 2001 and 2021, and their data were retrospectively collected. RESULTS: The most common primary cancer origin was lung in men (45%) and breast in women (33%)...
August 2023: Neurosurgical Focus
https://read.qxmd.com/read/37527678/association-of-cdkn2a-alterations-with-increased-postoperative-seizure-risk-after-resection-of-brain-metastases
#19
JOURNAL ARTICLE
Daniel D Cummins, Joseph H Garcia, Minh P Nguyen, Satvir Saggi, Jason E Chung, Ezequiel Goldschmidt, Mitchel S Berger, Philip V Theodosopoulos, Edward F Chang, Mariza Daras, Shawn L Hervey-Jumper, Manish K Aghi, Ramin A Morshed
OBJECTIVE: Seizures are common and significantly disabling for patients with brain metastases (BMs). Although resection can provide seizure control, a subset of patients with BMs may continue to suffer seizures postoperatively. Genomic BM characteristics may influence which patients are at risk for postoperative seizures. This work explores correlations between genomic alterations and risk of postoperative seizures following BM resection. METHODS: All patients underwent BM resection at a single institution, with available clinical and sequencing data on more than 500 oncogenes...
August 2023: Neurosurgical Focus
https://read.qxmd.com/read/37527677/survival-and-quality-of-life-after-csf-diversion-in-adult-patients-with-leptomeningeal-metastasis-associated-hydrocephalus-a-systematic-review-and-meta-analysis
#20
JOURNAL ARTICLE
Jasneet Dhaliwal, Michelle Ruiz-Perez, Anca Mihaela-Vasilica, Aswin Chari, Ciaran Scott Hill, Lewis Thorne
OBJECTIVE: Leptomeningeal metastasis (LM) is associated with altered CSF flow dynamics in 50%-70% of patients. Approximately 1%-5% of patients develop symptomatic LM-associated hydrocephalus (LM-H), which adversely impacts quality of life (QOL), functional status, and overall survival (OS). There is equipoise for CSF diversion procedures in LM-H. This systematic review and meta-analysis aimed to assess the effect of CSF diversion on OS and QOL in this context. METHODS: This systematic review was conducted according to the PRISMA guidelines...
August 2023: Neurosurgical Focus
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