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Japanese Journal of Infectious Diseases

https://read.qxmd.com/read/38684428/helicobacter-cholecystus-bacteremia-in-an-adult-with-acute-cholecystitis
#1
JOURNAL ARTICLE
Jinxia Su, Shunguang Li, Morui Chen, Zewei Huang, Huijun Liu, Pinghua Qu
We report the isolation of Helicobacter cholecystus from a positive blood culture from a 58-year-old man in China who had bacteremia and acute cholecystitis. The patient's condition improved after symptomatic support treatment and subtotal cholecystectomy. This finding suggests that H. cholecystus should be considered as potential human pathogens.
April 30, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38684427/anti-sars-cov-2-nucleocapsid-antibody-positivity-3-years-after-covid-19
#2
JOURNAL ARTICLE
Chang Kyung Kang, Youngju Kim, Hyeon Jae Jo, Chan Mi Lee, Nam Joong Kim, Chang-Han Lee, Pyoeng Gyun Choe, Wan Beom Park, Myoung-Don Oh
The accurate identification of individuals without prior infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is pivotal for seroepidemiological research and vaccine trials. Because of widespread COVID-19 vaccination, the anti-nucleocapsid antibody continues to serve as a valuable marker for individuals without a history of COVID-19. This study aimed to comprehensively assess anti-nucleocapsid antibody positivity using diverse commercial and in-house immunoassays among individuals who contracted COVID-19 more than 3 years ago...
April 30, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38556302/usefulness-of-a-pluralistic-approach-in-sentinel-surveillance-seasonal-influenza-activity-based-on-case-counts-per-sentinel-site-in-the-national-epidemiological-surveillance-of-infectious-diseases-program-and-test-counts-case-counts-and-test-positivity-from
#3
JOURNAL ARTICLE
Takeshi Arashiro, Yuzo Arima, Takuri Takahashi, Kiyosu Taniguchi, Hiromasa Horiguchi, Motoi Suzuki
In Japan, based on the National Epidemiological Surveillance of Infectious Diseases (NESID) Program, influenza cases from ~5,000 sentinel sites are monitored weekly as part of influenza surveillance (as number of influenza cases/sentinel site). One limitation is that the number of influenza tests conducted is not reported. Separately, the National Hospital Organization (NHO), with ~140 hospitals, routinely publishes three indicators: number of influenza tests, influenza-positive case counts, and test positivity...
March 29, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38556301/association-of-covrs-two-component-regulatory-system-with-nadase-induction-by-clindamycin-treatment-in-streptococcus-pyogenes
#4
JOURNAL ARTICLE
Ichiro Tatsuno, Masanori Isaka, Tadao Hasegawa
The administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic shock syndrome (STSS). However, CLI-resistant strains have been identified worldwide. Firstly, in this study, some CLI-resistant strains showed increased extracellular activities of the NAD- glycohydrolase (NADase) exotoxin after CLI treatment. This result supported our previous conclusion that not only CLI-susceptible but also CLI-resistant S. pyogenes strains show the CLI-dependent NADase induction...
March 29, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38556300/clinical-efficacy-of-therapeutic-agents-for-clostridioides-difficile-infection-based-on-four-severity-classifications
#5
JOURNAL ARTICLE
Mariko Ohtani, Sadako Yoshizawa, Taito Miyazaki, Eri Kumade, Shinobu Hirayama, Maki Sakamoto, Hinako Murakami, Tadashi Maeda, Yoshikazu Ishii, Takahiro Matsumoto, Kazuhiro Tateda
The Japanese guidelines for the management of Clostridioides difficile infection (CDI) recommend metronidazole (MNZ) for non-severe cases and vancomycin (VCM) for severe cases. Here, we investigated the use of CDI antimicrobials and evaluated their clinical efficacy in four severity classifications and the validity of these classifications. A retrospective chart review was conducted on 137 inpatients with an initial positive C. difficile toxin test and initiation of CDI antimicrobials between April 2015 and March 2019...
March 29, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38417867/clinical-course-and-molecular-characterization-of-human-bocavirus-associated-with-acute-lower-respiratory-tract-infections-in-tertiary-care-hospital-of-north-india
#6
JOURNAL ARTICLE
Subhabrata Sarkar, Mannat Kang, Suresh Kumar Angurana, Shankar Prasad, Ishani Bora, Pankaj Singh, Vikrant Sharma, Meenakshi Rana, Bhartendu Singh, Jayashree Muralidharan, Radha Kanta Ratho
Respiratory samples from 139 hospitalized children were screened for the Human Bocavirus (HBoV) genome. Positive samples were sequenced for partial VP1/VP2 gene followed by molecular and phylogenetic analyses. HBoV positivity was noted in 7.2% (10/139) patients. All HBoV positive children presented with fever followed by cough and respiratory distress (90%; 9/10). Three children developed multisystemic viral illness with one fatality. Eight children required intensive care management and mechanical ventilation required for 5 children...
February 29, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38417866/continuous-renal-replacement-therapy-improves-indicators-and-short-term-survival-in-people-with-aids-manifesting-sepsis-and-acute-kidney-injury
#7
JOURNAL ARTICLE
Jie Zheng, Qiu-Jin Yang, Fei Qi, Han-Zhang Shen, Le Zhang, Jia-Wei Xia
Acquired immune deficiency syndrome (AIDS) is susceptible to numerous complications such as sepsis and acute kidney injury (AKI), leading to adverse outcomes. Continuous renal replacement therapy (CRRT) is becoming increasingly popular in the treatment of sepsis and AKI. This study aimed to verify the effectiveness of CRRT in the treatment of AIDS with sepsis and AKI, to provide new directions for the treatment of severe AIDS. Data of 74 people with AIDS, sepsis and AKI were collected. They were divided into CRRT and non-CRRT groups...
February 29, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38417865/stss-by-streptococcus-pyogenes-emm22-genotype-accompanied-by-csrs-mutation-a-case-report
#8
JOURNAL ARTICLE
Kaoru Ogawa, Jiro Kamiyama, Tadayoshi Ikebe, Shigemasa Taguchi, Kazuya Kiyota
The patient was a 22-year-old woman with no comorbidities who was transferred to our hospital due to cardiac arrest. Treatment enabled return to spontaneous circulation in the patient before arriving at the hospital. At the hospital, the patient's vital signs were unstable. Vasopressors and hyperhydration therapy were administered. Computed Tomography (CT) showed no remarkable change that caused the cardiac arrest. Antibiotics were prescribed after a blood culture exam. The patient was admitted to the ICU. In the ICU, the high-capacity vasopressors, hyperhydration therapy and transfusion of fresh frozen plasma were continued...
February 29, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38417864/first-case-of-necrotizing-fasciitis-and-septicemia-caused-by-pigmentibacter-ruber
#9
JOURNAL ARTICLE
Ayumi Niwa, Masahiro Hayashi, Jun Yonetamari, Motohiro Nakamura, Yuta Yokobori, Sodai Yokoyama, Mizuki Ogawa, Rina Ichioka, Ryosuke Kikuchi, Hiroyuki Okura, Shinji Ogura, Nobuyuki Tetsuka, Kaori Tanaka, Hisashi Baba
We herein report the first case of necrotizing fasciitis caused by Pigmentibacter ruber. The isolated strain could not be identified by biochemical characterization and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). The isolated strain was identified as P. ruber by 16S ribosomal RNA and whole genome sequencing. Although much remains unknown about the pathogenicity of this bacterial specie in humans, it has been revealed to cause life-threatening infections, such as septicemia and necrotizing fasciitis...
February 29, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38417863/dissemination-of-urinary-escherichia-coli-phylogroup-b2-in-provincial-and-community-hospitals-in-uthai-thani-central-thailand
#10
JOURNAL ARTICLE
Chanihcha Anudit, Pornthip Saraisuwan, Chantana Kimterng, Chanakan Puangmanee, Nicharee Bamphensin, Anusak Kerdsin
Escherichia coli is a Gram-negative bacterium that prominently causes a variety of clinical infections in humans, such as diarrhea, sepsis, and urinary tract infection. This bacterium is a common multidrug-resistant threat in community and hospital settings worldwide. This study examined the antimicrobial susceptibility and genetic relationship based on Clermont phylotyping and ERIC-PCR of 84 E. coli urinary isolates from provincial and community hospitals in Thailand. All the isolates were completely susceptible to nitrofurantoin, whereas almost all isolates were susceptible to carbapenem, fosfomycin, and amikacin...
February 29, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38296545/proton-pump-inhibitors-and-risk-of-bloodstream-infection-without-an-identifiable-source-a-hospital-based-case-control-study
#11
JOURNAL ARTICLE
Shintaro Hayashi, Tomohito Moriyama, Yuichiro Ito, Yuta Harada, Hiroki Dodo, Kana Kumahara, Tatsuji Yogi, Noritsugu Ohashi, Reiji Higashi, Akihiro Mori
The association between proton-pump inhibitor (PPI) use and systemic infections caused by bacterial translocation is unclear. This study aims to investigate whether patients receiving PPI therapy have a higher risk for bloodstream infections (BSI) without an identifiable source of infection, as an alternative indicator of BSI secondary to bacterial translocation. We conducted a hospital-based case-control study which enrolled all patients aged 20 years and older who developed BSI confirmed by two sets of positive blood culture and had inpatient care in Ichinomiya-Nishi Hospital in 2019...
January 31, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38296544/genetic-comparison-of-human-parainfluenza-virus-type-3-detected-in-respiratory-samples-from-patients-with-encephalopathy-and-airway-inflammation-in-aichi-prefecture-japan
#12
JOURNAL ARTICLE
Hirokazu Adachi, Hiroko Minagawa, Emi Hirose, Noriko Nakamura, Hitomi Niimi, Noriko Saito, Miyabi Ito, Katsuhiko Sato, Yoshihiro Yasui
Human parainfluenza virus type 3 (HPIV-3, Human respirovirus 3) is the second most frequently detected virus after human respiratory syncytial virus (HRSV) in lower respiratory tract infections in children. HPIV-3, like its close relative respiratory viruses, HRSV and influenza virus, may cause encephalopathy, but the relevance of HPIV-3 as a pathogenic factor in encephalopathy is unknown. We attempted to detect HPIV-1 through 4, HRSV, and human metapneumovirus (HMPV) in 136 patients with encephalitis/encephalopathy, or suspected encephalitis/encephalopathy during a 6-year period from 2014 to 2019...
January 31, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38296543/the-efficacy-and-safety-of-nafamostat-mesylate-in-the-treatment-of-covid-19-a-meta-analysis
#13
JOURNAL ARTICLE
Mian Wei, Toni Li, Siyuan Liu, Yushu Wang, Carolyn Tran, Guangyu Ao
Nafamostat mesylate, a synthetic serine protease inhibitor, has demonstrated early antiviral activity against SARS-CoV-2 and anticoagulant properties that may be beneficial in COVID-19. We conducted a meta-analysis evaluating the efficacy and safety of nafamostat mesylate for COVID-19 treatment. PubMed, Embase, Cochrane Library, Scopus, Web of Science, medRxiv and bioRxiv were searched up to July 2023 for studies comparing outcomes between nafamostat mesylate treatment and no nafamostat mesylate treatment in COVID-19 patients...
January 31, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38296542/%C3%AE-lactam-susceptibility-of-streptococcus-dysgalactiae-subsp-equisimilis
#14
JOURNAL ARTICLE
Natsumi Nakashima, Wanchun Jin, Jun-Ichi Wachino, Shinobu Koyama, Kiyoko Tamai, Yoshichika Arakawa, Kouji Kimura
All clinical isolates of Streptococcus dysgalactiae subsp. equisimilis (SDSE) are considered susceptible to β-lactams, the first-line drugs used for SDSE infections. However, penicillin-non-susceptible SDSE has been reported from Denmark. In this study, we attempted to detect β-lactam-non-susceptible clinical isolates of SDSE in Japan. One hundred and fifty clinical isolates of S. dysgalactiae were collected in 2018, and species identification was performed using Rapid ID Strep API. The minimum inhibitory concentrations (MIC) of six β-lactams (penicillin G, oxacillin, ceftizoxime, ceftibuten, cefoxitin, and cefaclor) were determined for 85 clinical isolates of SDSE using the agar dilution method standardized by the Clinical Laboratory Standards Institute...
January 31, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38296541/inactivation-of-sars-cov-2-in-serum-using-physical-methods
#15
JOURNAL ARTICLE
Toshihiko Harada, Hirofumi Fujimoto, Shuetsu Fukushi, Koji Ishii, Ken-Ichi Hanaki
Since 2019, many studies on COVID-19, which has caused extensive damage as a pandemic, have been ongoing worldwide. These include serological and biochemical studies using sera from patients and animal models. Testing with these sera must be performed after the inactivation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Heat treatment, UV irradiation, and/or gamma-ray irradiation are used to inactivate viruses in serum. Determining the inactivation conditions that ensure the inactivation of viruses and minimize the effect on test results after inactivation is important to ensure worker safety and accuracy of test results...
January 31, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38296540/efficacy-of-cefiderocol-a-novel-siderophore-cephalosporin-against-multi-drug-resistant-acinetobacter-baumannii-clinical-isolates-in-japan
#16
JOURNAL ARTICLE
Yoshitaka Kimura, Nami Hatayama, Yoshinori Sato, Satoshi Nishida, Yusuke Yoshino
Multidrug-resistant Acinetobacter baumannii (MDRAB) is an important pathogen that causes nosocomial infections and is resistant to almost all antibiotics, including carbapenems. Cefiderocol is a novel siderophore cephalosporin that is active against a broad spectrum of Gram-negative bacteria. However, the susceptibility of MDRAB from Japan to cefiderocol has not yet been reported. In this study, we measured the minimum inhibitory concentrations (MICs) of antibiotics, including cefiderocol, against MDRAB clinical isolates collected during a nosocomial outbreak from 2009 to 2010 at Teikyo University Hospital in Japan...
January 31, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38296539/biofilm-eradication-of-stenotrophomonas-maltophilia-by-levofloxacin-and-trimethoprim-sulfamethoxazole
#17
JOURNAL ARTICLE
José Mauricio Del Río-Chacón, Fabián Rojas-Larios, Paola Bocanegra-Ibarias, Daniel Salas-Treviño, Francisco Espinoza-Gómez, Adrián Camacho-Ortiz, Samantha Flores-Treviño
Stenotrophomonas maltophilia is a non-fermenting Gram-negative drug-resistant pathogen causing healthcare-associated infections. Clinical isolates from Mexico were assessed for biofilm production by crystal violet staining. Antimicrobial susceptibility was evaluated using the broth microdilution method in planktonic and biofilm cells. The effect of antibiotics on the biofilm was visualized by fluorescence microscopy. Fifty isolates were included in the study, of which 28.0% were biofilm producers (64.2% from blood and 35...
January 31, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38296538/relationship-of-toll-like-receptor-7-9-and-10-polymorphisms-on-the-severity-of-covid-19
#18
JOURNAL ARTICLE
Burcu Bayyurt, Sevgi Baltacı, Nil Özbilüm Şahin, Serdal Arslan, Mehmet Bakır
COVID-19 is an pandemic that is still affecting today and has caused many deaths. Toll-like receptor (TLR) have an important role in the binding of disease agents to host cell, disease susceptibility and severity, host disease resistance, In this study, we investigated frequencies of TLR7 (C.4-151 A/G), TLR9 (T-1486C and G2848A), and TLR10 (720A/C and 992T/A) single nucleotide polymorphisms (SNPs) in 150 cases with COVID-19 and 171 control samples. We also observed whether TLR7, 9, and 10 were related with the COVID-19 disease severity...
January 31, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38296537/antimicrobial-resistance-patterns-of-common-gram-negative-microorganisms-isolated-from-patients-with-lower-respiratory-tract-infection-in-a-teaching-hospital-in-vietnam
#19
JOURNAL ARTICLE
Hoang Huy Le, An Van Nguyen, Luong Huy Vu, Vinh Thi Ha Nguyen, Hoa Quynh Pham, Hung Van Le, Son Thai Nguyen, Hong Thu Le, Hung Viet Dinh, Nam Van Le, Tuan Dinh Le, Minh Nhat Le, Viet Hoang Nguyen, Kien Trung Hoang, Hai Ha Long Le
This cross-sectional study investigated the antimicrobial resistance (AMR) patterns of Gram-negative pathogens isolated from 4,789 hospitalized patients with lower respiratory tract infections (LRTIs). Of the collected specimens, 1,325 (27.7%) specimens tested positive for Gram-negative bacteria. The most prevalent isolates were Acinetobacter baumannii (38.6%), Pseudomonas aeruginosa (33.5%), Klebsiella pneumoniae (18.7%), Escherichia coli (5.6%), and Klebsiella aerogenes (3.5%). Antimicrobial resistance analysis revealed high resistance rates among A...
January 31, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38267044/importance-of-toxin-genes-and-polymerase-chain-reaction-based-open-reading-frame-type-analyses-for-severe-staphylococcus-aureus-infection-in-children
#20
JOURNAL ARTICLE
Noriko Takeuchi, Naruhiko Ishiwada
No abstract text is available yet for this article.
2024: Japanese Journal of Infectious Diseases
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