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Archives of Iranian Medicine

Vitorino Modesto Dos Santos, Evandro Luiz Brum, Layssa Melo Feitosa, Kamila Fernandes Ferreira, Camila Azevedo Silva
No abstract text is available yet for this article.
December 1, 2018: Archives of Iranian Medicine
Cristiano de Assis Pereira Hansen, Jayr Schmidt Filho, Marina de Mattos Nascimento, Fábio Abreu Alves, Tatiane Neotti, Felipe D Almeida Costa
Extramedullary plasmacytomas occurs in about 20% of multiple myeloma (MM) recurrences. Extramedullary disease seems to respond poorly to thalidomide and has adverse prognostic implication. When disease recurs in the oral cavity with soft tissue infiltration, some authors defend upfront surgical excision prior to radiotherapy with the aim of achieving better local control. We describe herein such an atypical case of recurrence from MM, with complete local response after 2 cycles of chemotherapy. Unfortunately, disease progressed later on, and the patient died after 9 months post-recurrence...
December 1, 2018: Archives of Iranian Medicine
Enis Dikicier, Fatih Altintoprak
Gastritis cystica profunda (GCP) is a rare condition characterized by polypoid cystic ectasia of the submucosal layer with cystic dilatation of the glandular structures of the stomach. The probable pathogenesis refers to degradation of the integrity of the muscularis mucosa and migration of epithelial cells to the submucosal layer. The most common cause known in the literature for this occurrence is previous stomach surgery. A case presented with two GCP lesions in different locations in the stomach without any history of previous surgery...
December 1, 2018: Archives of Iranian Medicine
Moslem Bahadori, Mohammad Hossein Azizi, Shahriar Dabiri
The nucleolus is an internuclear organelle without a visible membrane via the light microscope inside the cell nucleus. It is the main site for synthesis of ribosome as a complex machine for coordinating protein production. It forms around a specific chromosomal feature called the nucleolar organizing region (NOR) which possesses numerous ribosomal DNA (rDNA). Although the nucleolus is best known as coordinator of ribosomal biogenesis and protein synthesis, recently, there is exciting awareness both on better understanding of ribosome biogenesis and non-ribosomal nucleolar functions...
December 1, 2018: Archives of Iranian Medicine
Farshad Nikouei, Hasan Ghandhari, Ebrahim Ameri, Seyed Mani Mahdavi, Maryam Ameri, Farshad Safdari
BACKGROUND: Growing rods are increasingly used for treatment of early onset scoliosis (EOS) worldwide. Beside promising outcomes, some authors are concerned about high rates of complications. In the current clinical trial, complications of EOS surgery using dual growing rods were investigated. METHODS: Between June 2006 and February 2017, twenty-two consecutive patients with a coronal curve >45 degrees underwent serial surgical correction using dual growing rods at Shafa Orthopedic hospital, Tehran, I...
December 1, 2018: Archives of Iranian Medicine
Mohammadreza Esmaeili Dooki, Leila Moslemi, Ali Akbar Moghadamnia, Morteza Alijanpour Aghamaleki, Ali Bijani, Mohammad Pornasrollah, Hassan Ashrafianamiri, Haji-Ghorban Nooreddin
BACKGROUND: Rickets is failure in mineralization of growing bone and cartilage due to extreme vitamin D deficiency (VDD). The study aimed to identify rickets among vitamin D deficient children and determine any relationship between clinical findings and paraclinical evidence. METHODS: This study was conducted in two stages. In the first stage, blood was drawn from 406 children aged 30-72 months for measurement of 25(OH)D level. Of these children, 108 had 25(OH)D levels of <20 ng/dL and were evaluated physically for signs and symptoms scores (0-1) of VDD and rickets...
December 1, 2018: Archives of Iranian Medicine
Nahid Hassanpour, Fatemeh Panahi, Fatemeh Naserpour, Vahid Karami, Jafar Fatahi Asl, Mehrdad Gholami
BACKGROUND: Extracorporeal shock wave lithotripsy (ESWL) is considered as the method of choice for treatment of most stone diseases. The present study aims to evaluate radiation dose received by patients undergoing ESWL. METHODS: In total, 46 patients from both genders were referred to the Shohadaye Ashayer hospital of Khorramabad, Iran and were included in the present study. Patients were positioned in anteroposterior (AP) projection and along 30° anterior oblique (AO) projection upon the X-ray fluoroscopy table and exposures were conducted...
December 1, 2018: Archives of Iranian Medicine
Luma Al-Bayati, Bahar Nayeri Fasaei, Shahin Merat, Alireza Bahonar
BACKGROUND: The normal colonic microbiota is associated with the etiology of ulcerative colitis (UC). Several bacterial species are associated with the initiation and amplification of disease process. However, the etiology and mechanism of UC are poorly understood. The present study aimed to investigate, characterize, and compare the main composition of the mucosa-associated intestinal microflora in colonoscopic biopsy specimens of UC and non-UC patients. METHODS: Aerobic and facultative-anaerobic mucosa-associated bacteria were isolated and diagnosed from colonoscopic biopsy specimens of 40 UC patients and 40 patients without UC...
December 1, 2018: Archives of Iranian Medicine
Maysam Rezapour, Armita Shahesmaeili, Ali Hossinzadeh, Razieh Zahedi, Hamid Najafipour, Mohammad Hossein Gozashti
BACKGROUND: The objective of this study was to compare various lipid ratios for detection of metabolic syndrome (MetS) in the Iranian general population. METHODS: This cross-sectional study involved 5677 subjects aged ≥18 years from the general population in Kerman, Iran. Associations between lipid ratio quartiles and MetS were analyzed using logistic regression models. The areas under receiver operating characteristic (ROC) was calculated to determine the accuracy of lipid ratios in predicting MetS...
December 1, 2018: Archives of Iranian Medicine
Behzad Damari, Sahand Riazi-Isfahani
BACKGROUND: Running for more than 25 years, the Women Health Volunteers (WHV) program in Iran has made many great achievements. Considering the new expectations from the health system, this national program needs to be revised and undergo fundamental changes. Although many studies have been conducted to evaluate this program, there still is a lack of a comprehensive nationwide assessment containing policy recommendations. METHODS: This study was conducted in a qualitative approach...
December 1, 2018: Archives of Iranian Medicine
Shahrzad Bazargan-Hejazi, Alireza Ahmadi, Anaheed Shirazi, Elaheh Ainy, Shirin Djalalinia, Seyed-Mohammad Fereshtehnejad, Nader Jahanmehr, Aliashgher Kiadaliri, Maziar Moradi-Lakeh, Mahboubeh Parsaeian, Farshid Pourmalek, Kazem Rahimi, Sadaf G Sepanlou, Arash Tehrani, Reza Malekzadeh, Mohsen Naghavi
BACKGROUND: The Global Burden of Disease (GBD) Study provides estimates of deaths, years of life lost (YLL), years of life lived with disability (YLD), and disability-adjusted life years (DALYs) due to 249 causes of death, 315 diseases and injuries, and 79 behavioral, environmental, occupational, and metabolic risk factors in 195 countries, territories, and regions by sex and 20 age categories in 195 countries and regions since 1990. In this study, we aimed to present the burden of road traffic injuries (RTIs) in Iran and 15 surrounding countries in 1990-2016...
December 1, 2018: Archives of Iranian Medicine
Moslem Bahadori, Mohammad Eslami, Mohammad Hossein Azizi
This is a brief look at the establishment and development of oral and maxillofacial pathology in Iran. The program of the oral and maxillofacial pathology at first was integrated into the curriculum of the Dental School of Tehran University in 1960. The Iranian Society of Oral and Maxillofacial Pathologists was officially founded in 1999.
November 1, 2018: Archives of Iranian Medicine
Eduardo Pérez-Campos Mayoral, Laura Pérez-Campos Mayoral, Gabriel Mayoral Andrade, María Teresa Hernández-Huerta, Margarito Martínez Cruz, Eduardo Pérez-Campos
No abstract text is available yet for this article.
November 1, 2018: Archives of Iranian Medicine
Mahbube Ebrahimpur, Mohammad Reza Mohajeri Tehrani, Mahnaz Pejman Sani
No abstract text is available yet for this article.
November 1, 2018: Archives of Iranian Medicine
Rambod Mozafari, Kamran Alimoghaddam, Hamed Sotoude, Ali Asadollahi-Amin
Myeloid sarcoma (MS) is a solid extra-medullary tumor of immature myeloid cells which could occur before, during or after remission of acute leukemia at any site on the body. Owing to variation in differential diagnosis, pathologic evaluation and immunohistochemical staining are essential for definitive diagnosis. Rarely, MS has been shown as an isolated extramedullary relapse (iEMR) after allogeneic stem cell transplantation (allo-SCT), which often does not necessarily result in bone marrow involvement. It seems that despite chemotherapy and graft-versus-leukemia (GVL) effects on bone marrow, leukemic cells could remain alive in the extra-medullary region...
November 1, 2018: Archives of Iranian Medicine
Saeed Alborzi, Afshin Azimirad, Mina Azimirad
Although endometriosis is not a newly discovered disease, it has still remained enigmatic. Understanding the pathophysiology of this disease is still one of the challenges of gynecology and reproductive medicine. Therefore, the subject of endometriosis treatment faces many questions to be answered. Even though this is not considered to be a rare disease, testing novel treatments on subjects is definitely contrary to medical ethics. This is where importance of animal studies is emphasized. History of animal studies on endometriosis dates back to the time when the young John Sampson presented his theory of retrograde flow of menstruation to the gynecologic society of his time to explain the mechanism of endometriosis...
November 1, 2018: Archives of Iranian Medicine
Farzaneh Lotfi, Fariborz Bahrehmand, Asad Vaisi-Raygani, Reza Khodarahmi, Maryam Tanhapour, Amir Kiani, Zohreh Rahimi, Tayebeh Pourmotabbed
BACKGROUND: Discovering the association between genetic variations of metabolizing enzymes with idiopathic diseases such as ulcerative colitis (UC) may not only be an auxiliary agent in diagnosis but also could be an effective pharmacotherapy for inflammatory bowel disease (IBD). The aim of the present case-control study was to determine the association of cytochrome P450 2D6 (CYP2D6 *4), N-acteyltransferase-2 (NAT2*7) and multidrug resistance 1 (MDR1) 3435 C/T genotypes with UC susceptibility and thiopurine methyltransferase (TPMT) enzyme activity...
November 1, 2018: Archives of Iranian Medicine
Banafsheh Nikfar, Bahram Moazzami, Shahla Chaichian, Leila Ghalichi, Mahnaz Ekhlasi-Hundrieser, Mohammadreza Chashmyazdan, Batool Kazemi, Fatemeh Soltan, Mahshid Bozorgizadeh, Meisam Akhlaghdoust, Marzie Salehi, Yousef Alimohamadi
BACKGROUND: Having good quality of sleep is essential to good health. Sleep disorders could incur intangible expenses. The aim of this cross-sectional study was to evaluate the Persian version of the Pittsburgh Sleep Quality Index (PSQI-P) questionnaire administered to 3 categories of workers (clinical personnel, clerical staff, and logistics workers) in a private hospital located in Tehran, Iran. METHODS: In 2017, all Pars hospital personnel were invited to participate in the study...
November 1, 2018: Archives of Iranian Medicine
Yelda Dere, Ayşegül Aksoy Altınboğa, Emel Yaldır, Kaan Bal, Kürşad Tosun, Ayşegül Sarı
BACKGROUND: Gleason score is one of the strongest prognostic predictors of prostate cancer;however, a change was published which is a 5 step grouping system of prostatic adenocarcinomas according to their Gleason scores. The aim of this study is to determine the relationship between histopathological findings and prognosis of tumors subgrouped according to the new Gleason grade grouping system. METHODS: A total of 163 radical prostatectomies subgrouped into 5 prognostic groups were investigated for prognostic features such as pathological stage, extraprostatic extension, surgical margin status, involvement of seminal vesicles, perineural invasion, necrosis, vascular invasion, ganglionic involvement, concomitant high grade prostatic intraepithelial neoplasia (HPIN) in addition to other microscopic features of tumors such as the presence of mucin and foamy cytoplasmic change between groups...
November 1, 2018: Archives of Iranian Medicine
Zeinab Falakian, Tina Shahani, Razieh Rezaie, Saeideh Mazloomzadeh, Feridoon Sirati, Ahmad Jalilvand, Farzaneh Jahangiri, Parisa Bahmani, Farzaneh Jadali, Shahrokh Atarian, Reza Eghdam-Zamir, Alireza Biglari
BACKGROUND: Reduction in the level of tissue decorin is a hallmark of many types of cancer including breast carcinoma. However, reduced decorin expression has also been reported in several types of benign tumors to the extent that it has been proposed as a tissue marker to differentiate malignant from benign tumors. The aim of this study was to investigate the potential role of plasma decorin to distinguish breast cancer from fibroadenoma, the second most common type of benign tumor, after fibrocystic disease...
November 1, 2018: Archives of Iranian Medicine
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