journal
https://read.qxmd.com/read/37971596/challenges-in-conducting-clinical-trials-for-preeclampsia
#21
REVIEW
T Caroline Bank, Diana Kline, Maged M Costantine
PURPOSE OF REVIEW: To review recent data describing the challenges and innovations in therapeutic research focused on the prevention and treatment of preeclampsia. RECENT FINDINGS: Pregnant individuals have traditionally been excluded from therapeutic research, resulting in a paucity of innovation in therapeutics for pregnancy-specific medical conditions, especially preeclampsia. With the increased awareness of maternal morbidity and mortality, there is significant interest among researchers to expand therapeutic research in pregnancy...
November 16, 2023: Current Hypertension Reports
https://read.qxmd.com/read/37948020/effects-of-the-timing-of-intense-physical-activity-on-hypertension-risk-in-a-general-population-a-uk-biobank-study
#22
REVIEW
Xiaying Li, Jingjing Zeng, Bo Chen, Menglin Fan, Jie Wang, Lingqi Wei, Yong Ren, Shaoyong Xu
PURPOSE OF REVIEW: It has recently been suggested that the timing of exercise is important in the subsequent development of hypertension. We used the UK Biobank database which prospectively collates data in over 500,000 people aged between 40 and 69 years to determine the relationship between the chronoactivity pattern of exercise and the risk of incident hypertension. RECENT FINDINGS: We analyzed data from 70,617 participants with 7-day Axivity AX3 triaxial accelerometry information available...
November 10, 2023: Current Hypertension Reports
https://read.qxmd.com/read/37921937/a-narrative-review-of-the-effects-of-mindfulness-on-sleep-and-hypertension
#23
REVIEW
Daniel A Kusko, Jason Blake, Rebecca Williams
PURPOSE OF REVIEW: The prevalence of both insomnia and hypertension in the general population is vast and the health implications to individuals and society are costly. The current pharmacological treatment options for insomnia and hypertension are limited and patients are becoming increasingly interested in non-pharmacological treatment options. Mindfulness, a disciplined mental training practice rooted in Eastern traditions, has become a widely popular treatment method for multiple chronic health problems...
November 3, 2023: Current Hypertension Reports
https://read.qxmd.com/read/37747576/management-of-hyperkalemia-in-patients-with-chronic-kidney-disease-using-renin-angiotensin-aldosterone-system-inhibitors
#24
REVIEW
Michelle A Fravel, Calvin J Meaney, Lama Noureddine
PURPOSE OF REVIEW: Use of renin-angiotensin-aldosterone system (RAAS) inhibiting medications is critical in the prevention of cardiovascular disease and kidney function decline in patients with chronic kidney disease (CKD); however, these agents can lead to hyperkalemia, an electrolyte disorder associated with risk of arrythmia, conduction disorders, and increased overall mortality. Discontinuation, or reduction of dose, of RAAS inhibitor therapy in hyperkalemic patients with CKD can lead to loss of kidney and cardiovascular protection afforded by these medications...
November 2023: Current Hypertension Reports
https://read.qxmd.com/read/37642805/predicting-changes-in-systolic-and-diastolic-blood-pressure-of-hypertensive-patients-in-indonesia-using-machine-learning
#25
REVIEW
Desy Nuryunarsih, Lucky Herawati, Atik Badi'ah, Jenita Doli Tine Donsu, Okatiranti
PURPOSE OF REVIEW: This retrospective study investigated factors that influence the occurrence of decreased systolic and diastolic blood pressure including sociodemographic and economic factors, hypertension duration, cigarette consumption, alcohol consumption, duration of smoking, type of cigarettes, exercise, salt consumption, sleeping pills consumption, insomnia, and diabetes. These factors were applied to predict the reality of systolic and diastolic decrease using the machine learning algorithm Naïve Bayes, artificial neural network, logistic regression, and decision tree...
November 2023: Current Hypertension Reports
https://read.qxmd.com/read/37906342/clinical-significance-of-nocturnal-hypertension-and-nighttime-blood-pressure-dipping-in-hypertension
#26
REVIEW
Panagiota Anyfanti, Anastasia Malliora, Agapi Chionidou, Konstantinos Mastrogiannis, Antonios Lazaridis, Eugenia Gkaliagkousi
PURPOSE OF REVIEW: This narrative review article aims to discuss more recent evidence, current challenges, and future perspectives regarding the clinical importance of nocturnal hypertension and nighttime blood pressure dipping, with particular reference to diagnosis, prognostic value, and therapeutic approach. RECENT FINDINGS: The importance of nighttime blood pressure and nighttime blood pressure dipping has been demonstrated in decades. Increased nighttime blood pressure has been acknowledged as an unfavorable clinical trait...
October 31, 2023: Current Hypertension Reports
https://read.qxmd.com/read/37878224/salty-subjects-unpacking-racial-differences-in-salt-sensitive-hypertension
#27
REVIEW
Soolim Jeong, Stacy D Hunter, Marc D Cook, Gregory J Grosicki, Austin T Robinson
PURPOSE OF REVIEW: To review underlying mechanisms and environmental factors that may influence racial disparities in the development of salt-sensitive blood pressure. RECENT FINDINGS: Our group and others have observed racial differences in diet and hydration, which may influence salt sensitivity. Dietary salt elicits negative alterations to the gut microbiota and immune system, which may increase hypertension risk, but little is known regarding potential racial differences in these physiological responses...
October 25, 2023: Current Hypertension Reports
https://read.qxmd.com/read/37837518/pressure-building-against-the-clock-the-impact-of-circadian-misalignment-on-blood-pressure
#28
REVIEW
Brooke M Shafer, Sophia A Kogan, Andrew W McHill
PURPOSE OF REVIEW: Misalignment between the endogenous biological timing system and behavioral activities (i.e., sleep/wake, eating, activity) contributes to adverse cardiovascular health. In this review, we discuss the effects of recurring circadian misalignment on blood pressure regulation and the implications for hypertension development. Additionally, we highlight emerging therapeutic approaches designed to mitigate the negative cardiovascular consequences elicited by circadian disruption...
October 14, 2023: Current Hypertension Reports
https://read.qxmd.com/read/37837517/microvascular-dysfunction-in-obesity-hypertension
#29
REVIEW
Tammy Do, Ashley Van, Arash Ataei, Swati Sharma, Rajesh Mohandas
PURPOSE OF REVIEW: This review aims to explore the role of microvascular dysfunction in obesity-hypertension, discuss the effects obesity has on renal microvasculature, review the current methods for assessing microvascular dysfunction and available therapeutic options, and identify critical areas for further research. RECENT FINDINGS: There is a strong association between obesity and hypertension. However, the pathophysiology of obesity-hypertension is not clear...
October 14, 2023: Current Hypertension Reports
https://read.qxmd.com/read/37815726/correction-to-does-renal-denervation-a-reasonable-treatment-option-in-hemodialysis-dependent-patient-with-resistant-hypertension-a-narrative-review
#30
Alberto Mazza, Fabio Dell'Avvocata, Gioia Torin, Francesca Bulighin, Yuri Battaglia, Fulvio Fiorini
No abstract text is available yet for this article.
October 10, 2023: Current Hypertension Reports
https://read.qxmd.com/read/37815725/correction-to-masked-hypertension-in-healthy-children-and-adolescents-who-should-be-screened
#31
Tomáš Seeman, Terezie Šuláková, Stella Stabouli
No abstract text is available yet for this article.
October 10, 2023: Current Hypertension Reports
https://read.qxmd.com/read/37787865/role-of-inflammatory-processes-in-the-brain-body-relationship-underlying-hypertension
#32
REVIEW
Daniela Carnevale
PURPOSE OF REVIEW: Essential hypertension is a huge health problem that significantly impacts worldwide population in terms of morbidity and mortality. Idiopathic in its nature, elevated blood pressure results from a complex interaction between polygenic components and environmental and lifestyle factors. The constant growth in the burden of hypertension is at odds with expectations, considering the availability of therapeutic strategies. Hence, there is an endless need to further investigate the complexity of factors contributing to blood pressure elevation...
October 3, 2023: Current Hypertension Reports
https://read.qxmd.com/read/37787864/key-to-the-treatment-of-primary-aldosteronism-in-secondary-hypertension-subtype-diagnosis
#33
REVIEW
Rui Zuo, Shuang Liu, Lu Xu, Hua Pang
PURPOSE OF REVIEW: Primary aldosteronism (PA) is a leading global cause of secondary hypertension. Subtyping diagnosis of PA is the key to surgery, but accurate classification of PA is crucial but challenging in clinical diagnosis and treatment. The purpose of this review is to provide a summary of current literature and propose subtyping diagnosis flow chart to help us classify PA quickly and accurately. RECENT FINDINGS: Early diagnosis and accurate typing are essential for the timely treatment and appropriate management of PA...
October 3, 2023: Current Hypertension Reports
https://read.qxmd.com/read/37581768/benzodiazepines-reduce-blood-pressure-in-short-term-a-systematic-review-and-meta-analysis
#34
REVIEW
Bhupinder Solanki, Ridhi Goel, Lalit K Gupta
PURPOSE OF REVIEW: Benzodiazepines, due to their anxiolytic properties, are prescribed to reduce anxiety and insomnia. They might have hypotensive effect via potentiation of the inhibitory effect of gamma-amino butyric acid (GABA) in the central nervous system and vasodilatory properties. However, studies comparing the effect of benzodiazepines in lowering blood pressure (BP) are equivocal. This systematic review and meta-analysis was planned to assess the efficacy of benzodiazepines in reducing blood pressure in short term among hypertensive patients...
October 2023: Current Hypertension Reports
https://read.qxmd.com/read/37505377/standardizing-blood-pressure-measurements-in-pediatric-hemodialysis-a-collaborative-journey
#35
REVIEW
Audrey B Anaya, Marsha M Lee, Alicia M Neu, Sarah M Swartz, Jessica J Geer, Bradley A Warady
PURPOSE OF REVIEW: This manuscript details the development and execution of a quality improvement (QI) initiative aimed at standardizing blood pressure (BP) measurement practices in pediatric hemodialysis (HD) units across a national dialysis collaborative. RECENT FINDINGS: Although there are recommendations for the detection and treatment of hypertension in the pediatric population, currently there is no data or recommendations specific to the methodology of measuring blood pressure in a pediatric hemodialysis setting...
October 2023: Current Hypertension Reports
https://read.qxmd.com/read/37733162/angiotensin-receptor-blockers-and-cognition-a-scoping-review
#36
REVIEW
Zhen Zhou, Suzanne G Orchard, Mark R Nelson, Michelle A Fravel, Michael E Ernst
PURPOSE OF REVIEW: To provide an overview of the association between angiotensin II receptor blocker (ARB) use and cognitive outcomes. RECENT FINDINGS: ARBs have previously shown greater neuroprotection compared to other anti-hypertensive classes. The benefits are primarily attributed to the ARB's effect on modulating the renin-angiotensin system via inhibiting the Ang II/AT1R pathway and activating the Ang II/AT2R, Ang IV/AT4R, and Ang-(1-7)/MasR pathways. These interactions are associated with pleiotropic neurocognitive benefits, including reduced β-amyloid accumulation and abnormal hyperphosphorylation of tau, ameliorated brain hypo-fusion, reduced neuroinflammation and synaptic dysfunction, better neurotoxin clearing, and blood-brain barrier function restoration...
September 21, 2023: Current Hypertension Reports
https://read.qxmd.com/read/37676461/role-of-female-sex-hormones-and-immune-response-in-salt-sensitive-hypertension-development-evidence-from-experimental-models
#37
REVIEW
Sandra G Vlachovsky, Luis A Di Ciano, Elisabet M Oddo, Pablo J Azurmendi, Claudia Silberstein, Fernando R Ibarra
PURPOSEOF REVIEW: Female sex hormones have systemic effects unrelated to their reproductive function. We describe experiences of different research groups and our own, on aspects related to the importance of female sex hormones on blood pressure (BP) regulation and salt-sensitivity-mediated BP response and salt sensitivity without alterations in BP, as well as renal sodium handling and interactions with the immune system. RECENT FINDINGS: Changes in sodium intake in normotensive premenopausal women cause more BP variations than in men...
September 7, 2023: Current Hypertension Reports
https://read.qxmd.com/read/37672130/does-renal-denervation-a-reasonable-treatment-option-in-hemodialysis-dependent-patient-with-resistant-hypertension-a-narrative-review
#38
REVIEW
Mazza Alberto, Dell'Avvocata Fabio, Torin Gioia, Francesca Bulighin, Battaglia Yuri, Fiorini Fulvio
PURPOSE OF REVIEW: This narrative review aims to assess the pathophysiology, diagnosis, and treatment of resistant hypertension (RH) in end-stage kidney disease (ESKD) patients on dialysis, with a specific focus on the effect of renal denervation (RDN) on short-term and long-term blood pressure (BP) control. Additionally, we share our experience with the use of RDN in an amyloidotic patient undergoing hemodialysis with RH. RECENT FINDINGS: High BP, an important modifiable cardiovascular risk factor, is often observed in patients in ESKD, despite the administration of multiple antihypertensive medications...
September 6, 2023: Current Hypertension Reports
https://read.qxmd.com/read/37284934/ace-inhibitors-in-hypertension-a-historical-perspective-and-current-insights
#39
REVIEW
Stacey Cutrell, Ibrahim S Alhomoud, Anurag Mehta, Azita H Talasaz, Benjamin Van Tassell, Dave L Dixon
PURPOSE OF REVIEW: This review describes the discovery and development of ACE inhibitors as antihypertensive agents, compares their efficacy, tolerability, and safety to ARBs, and highlights the contemporary issues surrounding ACE inhibitor use for HTN. RECENT FINDINGS: Angiotensin-converting enzyme (ACE) inhibitors are commonly prescribed medications for the management of hypertension (HTN) and other chronic conditions including heart failure and chronic kidney disease...
September 2023: Current Hypertension Reports
https://read.qxmd.com/read/37639176/masked-hypertension-in-healthy-children-and-adolescents-who-should-be-screened
#40
REVIEW
Seeman Tomáš, Šuláková Terezie, Stabouli Stella
PURPOSE OF REVIEW: The goal is to review masked hypertension (MH) as a relatively new phenomenon when patients have normal office BP but elevated out-of-office BP. Firstly, it was described in children in 2004. It has received increased attention in the past decade. RECENT FINDINGS: The prevalence of MH in different pediatric populations differs widely between 0 and 60% based on the population studied, definition of MH, or method of out-of-office BP measurement...
August 28, 2023: Current Hypertension Reports
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