journal

Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine | Page 2

journal
https://read.qxmd.com/read/31778633/the-burden-of-antibiotic-allergies-in-adults-in-an-australian-intensive-care-unit-the-basis-study
#21
Rebekah L Moran, Misha Devchand, Leonid Churilov, Stephen Warrillow, Jason A Trubiano
OBJECTIVE: To determine the prevalence and impact of patient-reported antibiotic allergies in the intensive care unit (ICU), which are currently poorly defined. Antibiotic allergy labels (AALs) are associated with inappropriate antibiotic prescribing and with inferior patient, microbiological and hospital outcomes. DESIGN: Prospective, single-centre case-control study. SETTING: Mixed ICU, Austin Hospital, Melbourne. PARTICIPANTS: All adults (≥ 18 years old) admitted to the ICU who received at least two doses of systemic antibiotics between 12 February and 20 April 2018...
December 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31778632/a-pilot-randomised-controlled-trial-evaluating-the-pharmacodynamic-effects-of-furosemide-versus-acetazolamide-in-critically-ill-patients
#22
RANDOMIZED CONTROLLED TRIAL
Alastair Jw Brown, Salvatore L Cutuli, Glenn M Eastwood, Laurent Bitker, Philip Marsh, Rinaldo Bellomo
OBJECTIVE: To compare the physiological and biochemical effects of a single intravenous dose of furosemide or acetazolamide in critically ill patients. DESIGN: Single centre, pilot randomised controlled trial. SETTING: Large tertiary adult intensive care unit (ICU). PARTICIPANTS: Twenty-six adult ICU patients deemed to require diuretic therapy. INTERVENTION: Single dose of intravenous 40 mg furosemide or 500 mg acetazolamide...
December 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31778631/small-volume-vacuum-phlebotomy-tubes-a-controlled-before-and-after-study-of-a-patient-blood-management-initiative-in-an-australian-adult-intensive-care-unit
#23
Edward N Briggs, David J Hawkins, Aidan M Hodges, Angela M Monk
BACKGROUND: Patients admitted to intensive care units (ICUs) undergo multiple blood tests. Small volume vacuum phlebotomy tubes (SVTs) provide an important blood conservation measure. SVTs reduce summative blood loss and may reduce odds of transfusion. We aimed to determine whether low volume blood sampling using SVTs for routine diagnostic purposes translates to decreased fall in haemoglobin concentration, and examine downstream effects on anaemia and need for transfusion during ICU admission...
December 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31778630/low-tidal-volume-ventilation-during-anaesthesia-for-major-surgery-protocol-and-statistical-analysis-plan
#24
Dharshi Karalapillai, Laurence Weinberg, Phil Peyton, Louise Ellard, Raymond Hu, Brett Pearce, Chong Tan, David Story, Mark ODonnell, Patrick Hamilton, Chad Oughton, Jonathan Galtieri, Anthony Wilson, Ary Serpa Neto, Glenn Eastwood, Rinaldo Bellomo, Daryl A Jones
BACKGROUND: Mechanical ventilation is mandatory in patients undergoing general anaesthesia for major surgery. Tidal volumes higher than 10 mL/kg of predicted body weight have been advocated for intraoperative ventilation, but recent evidence suggests that low tidal volumes may benefit surgical patients. To date, the impact of low tidal volume compared with conventional tidal volume during surgery has only been assessed in clinical trials that also combine different levels of positive end-expiratory pressure (PEEP) in each arm...
December 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31778629/pharmacokinetic-data-support-6-hourly-dosing-of-intravenous-vitamin-c-to-critically-ill-patients-with-septic-shock
#25
RANDOMIZED CONTROLLED TRIAL
Elizabeth P Hudson, Jake Tb Collie, Tomoko Fujii, Nora Luethi, Andrew A Udy, Sarah Doherty, Glenn Eastwood, Fumitaka Yanase, Thummaporn Naorungroj, Laurent Bitker, Yasmine Ali Abdelhamid, Ronda F Greaves, Adam M Deane, Rinaldo Bellomo
OBJECTIVES: To study vitamin C pharmacokinetics in septic shock. DESIGN: Prospective pharmacokinetic study. SETTING: Two intensive care units. PARTICIPANTS: Twenty-one patients with septic shock enrolled in a randomised trial of high dose vitamin C therapy in septic shock. INTERVENTION: Patients received 1.5 g intravenous vitamin C every 6 hours. Plasma samples were obtained before and at 1, 4 and 6 hours after drug administration, and vitamin C concentrations were measured by high performance liquid chromatography...
December 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31778628/addressing-high-practice-variability-in-reported-management-of-burns
#26
Michael C Reade
No abstract text is available yet for this article.
December 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31778627/o-2-do-we-know-what-to-do
#27
Paul J Young, Sean M Bagshaw, Michael Bailey, Rinaldo Bellomo, Diane Mackle, David Pilcher, Giovanni Landoni, Alistair Nichol, Daniel Martin
No abstract text is available yet for this article.
December 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31778626/in-this-issue-of-ccr
#28
Rinaldo Bellomo
No abstract text is available yet for this article.
December 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31462209/duration-of-intravenous-vitamin-c-therapy-is-a-critical-consideration
#29
Anitra C Carr
No abstract text is available yet for this article.
September 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31462208/cumulative-radiation-in-critically-ill-patients-a-retrospective-audit-of-ionising-radiation-exposure-in-an-intensive-care-unit
#30
James H McEvoy, Shailesh Bihari, Antony M Hooker, Dani-Louise Dixon
OBJECTIVE: Ionising radiation is a valuable tool in modern medicine including for patients in an intensive care unit (ICU). However, clinicians are faced with a trade-off between benefit of information received from procedure versus risks associated with radiation. As a first step to understanding the risk and benefits of radiation exposure to ICU patients, we aimed to assess the cumulative levels of ionising radiation patients receive during their ICU stay. DESIGN: Retrospective audit...
September 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31462207/aboriginal-and-torres-strait-islander-patients-requiring-critical-care-characteristics-resource-use-and-outcomes
#31
COMPARATIVE STUDY
Paul Secombe, Alex Brown, Greg McAnulty, David Pilcher
OBJECTIVE: To provide a contemporary description of the demographics, characteristics and outcomes of critically ill Indigenous patients in Australia. DESIGN, SETTING AND PARTICIPANTS: Retrospective database review using the Australian and New Zealand Intensive Care Society Adult Patient Database for intensive care unit (ICU) admissions in 2017-18. Characteristics of critically ill Indigenous patients were compared with non-Indigenous patients. MAIN OUTCOME MEASURES: Primary outcome was hospital mortality...
September 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31462206/characteristics-management-and-outcomes-of-patients-with-acute-liver-failure-admitted-to-australasian-intensive-care-units
#32
Stephen Warrillow, Heath Tibballs, Michael Bailey, Colin McArthur, Pia Lawson-Smith, Bheemasenachar Prasad, Matthew Anstey, Balasubramanian Venkatesh, Gemma Dashwood, James Walsham, Andrew Holt, Ubbo Wiersema, David Gattas, Matthew Zoeller, Mercedes Garcia Alvarez, Rinaldo Bellomo
OBJECTIVE: Acute liver failure (ALF) leads to severe illness and usually requires admission to the intensive care unit (ICU). Despite its importance, little is known about patients with ALF in Australia and New Zealand. DESIGN: Binational observational study to evaluate the aetiology, baseline characteristics, patterns of illness, management, and outcomes for patients with ALF admitted to Australian and New Zealand ICUs. SETTING: All six Australian and New Zealand ICUs in liver transplant centres submitted de-identified data for ten or more consecutive patients with ALF...
September 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31462205/the-epidemiology-of-in-hospital-cardiac-arrests-in-australia-a-prospective-multicentre-observational-study
#33
(no author information available yet)
BACKGROUND: Australian in-hospital cardiac arrest (IHCA) literature is limited, and mostly published before rapid response teams (RRTs). Contemporary data may inform strategies to improve IHCA outcomes. STUDY DESIGN: Prospective observational study of ward adult IHCAs in seven Australian hospitals. PARTICIPANTS AND OUTCOMES: IHCA was defined as unresponsiveness, no respiratory effort, and commencement of external cardiac compressions. Data included IHCA frequency, patient demographics, resuscitation management, intensive care unit (ICU) management, and hospital discharge status...
September 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31462204/targeted-fibrinogen-concentrate-use-in-severe-traumatic-haemorrhage
#34
Jacqueline A Seebold, Don Campbell, Elizabeth Wake, Kerin Walters, Debbie Ho, Erick Chan, Andrew C Bulmer, Martin Wullschleger, James Winearls
OBJECTIVE: Fibrinogen is one of the first coagulation factors to be depleted during traumatic haemorrhage, and evidence suggests hypofibrinogenaemia leads to poor outcomes. A number of fibrinogen replacement products are currently available, with no clear consensus on the ideal product to use in severe traumatic haemorrhage. We hypothesised that it will be possible to rapidly administer fibrinogen concentrate (FC) guided by rotational thromboelastometry (ROTEM) FIBTEM A5 in patients presenting with trauma haemorrhage...
September 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31462203/statistical-analysis-plan-for-the-standard-versus-accelerated-initiation-of-renal-replacement-therapy-in-acute-kidney-injury-starrt-aki-trial
#35
(no author information available yet)
BACKGROUND: The Standard versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial is a multinational randomised controlled trial that will enrol a minimum of 2866 patients comparing two strategies for initiating renal replacement therapy in critically ill patients with acute kidney injury. OBJECTIVE: To describe a pre-specified statistical analysis plan (SAP) for the STARRT-AKI trial before completion of patient recruitment and data collection...
September 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31462202/capacity-to-train-and-the-intensive-care-workforce
#36
(no author information available yet)
No abstract text is available yet for this article.
September 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31462201/renal-replacement-therapy-in-the-icu-when-should-we-starrt
#37
Rinaldo Bellomo
No abstract text is available yet for this article.
September 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31462200/comparing-apples-and-oranges-the-vasoactive-effects-of-hydrocortisone-and-studies-investigating-high-dose-vitamin-c-combination-therapy-in-septic-shock
#38
Tomoko Fujii, Andrew A Udy, Balasubramanian Venkatesh
No abstract text is available yet for this article.
September 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31462199/in-this-issue-of-ccr
#39
Rinaldo Bellomo
No abstract text is available yet for this article.
September 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/31142245/a-practice-survey-of-airway-management-in-australian-and-new-zealand-intensive-care-units
#40
Michael Toolis, Ravindranath Tiruvoipati, John Botha, Cameron Green, Ashwin Subramaniam
OBJECTIVE: To characterise intubation practices in Australian and New Zealand intensive care units (ICUs) and investigate clinician support for establishing airway management guidelines in Australian and New Zealand ICUs. DESIGN: An online survey was designed, piloted and distributed to members of the mailing list of the Australian and New Zealand Intensive Care Society (ANZICS), with medical members invited to participate. Respondents were excluded if their primary practice was in paediatric ICUs...
June 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
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