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Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine

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https://read.qxmd.com/read/30857515/reported-practice-of-temperature-adjustment-%C3%AE-stat-v-ph-stat-for-arterial-blood-gases-measurement-among-investigators-from-two-major-cardiac-arrest-trials
#1
Glenn M Eastwood, Niklas Nielsen, Alistair D Nichol, Markus B Skrifvars, Craig French, Rinaldo Bellomo
BACKGROUND: Two major cardiac arrest trials are evaluating different strategies that may potentially mitigate neurological injury after cardiac arrest and are allowing co-enrolment. However, one trial will target hypothermia and the other will target mild hypercapnia, in which the carbon dioxide (CO2 ) measurement may be influenced by the choice of temperature adjustment during arterial blood gases (ABGs) measurement. The trials have agreed to standardise assessment by the α-stat method...
March 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30857514/a-protocol-for-a-phase-3-multicentre-randomised-controlled-trial-of-continuous-versus-intermittent-%C3%AE-lactam-antibiotic-infusion-in-critically-ill-patients-with-sepsis-bling-iii
#2
Jeffrey Lipman, Stephen J Brett, Jan J De Waele, Menino O Cotta, Joshua S Davis, Simon Finfer, Parisa Glass, Serena Knowles, Shay McGuinness, John Myburgh, David L Paterson, Sandra Peake, Dorrilyn Rajbhandari, Andrew Rhodes, Jason A Roberts, Charudatt Shirwadkar, Therese Starr, Colman Taylor, Laurent Billot, Joel M Dulhunty
BACKGROUND AND RATIONALE: β-Lactam antibiotics display a time-dependent mechanism of action, with evidence suggesting improved outcomes when administering these drugs via continuous infusion compared with standard intermittent infusion. However, there is no phase 3 randomised controlled trial (RCT) evidence to support one method of administration over another in critically ill patients with sepsis. DESIGN AND SETTING: The β-Lactam Infusion Group (BLING) III study is a prospective, multicentre, open, phase 3 RCT to compare continuous infusion with standard intermittent infusion of β-lactam antibiotics in critically ill patients with sepsis...
March 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30857513/clinical-management-practices-of-life-threatening-asthma-an-audit-of-practices-in-intensive-care
#3
Paul Secombe, Penny Stewart, Sunil Singh, Lewis Campbell, Dianne Stephens, Khoa Tran, Hayden White, Robert Sheehy, Justine Gibson, Robyn Cooke, Shane Townsend, Yogesh Apte, James Winearls, Olivia R Ferry, Rahul Pradhan, Marc Ziegenfuss, Kwun M Fong, Ian A Yang, Paul McGinnity, Jason Meyer, James Walsham, Rob Boots, Pierre Clement, Hiran Bandeshe, Christopher Gracie, Paul Jarret, Stephenie Collins, Caitlin Coulston, Melisa Ng, Valerie Howells, Indranil Chatterjee, Adam Visser, Judy Smith, Melita Trout
OBJECTIVE: Lack of management guidelines for lifethreatening asthma (LTA) risks practice variation. This study aims to elucidate management practices of LTA in the intensive care unit (ICU). DESIGN: A retrospective cohort study. SETTING: Thirteen participating ICUs in Australia between July 2010 and June 2013. PARTICIPANTS: Patients with the principal diagnosis of LTA. MAIN OUTCOME MEASURES: Clinical history, ICU management, patient outcomes, ward education and discharge plans...
March 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30857512/early-electroencephalogram-does-not-reliably-differentiate-outcomes-in-post-hypoxic-myoclonus
#4
Linda J Dalic, Gerard Fennessy, Mark Edmonds, Patrick Carney, Helen Opdam, John Archer
OBJECTIVE: Prognostication in patients with post-hypoxic brain injury remains difficult; yet, clinicians are commonly asked to guide decisions regarding withdrawal of life support. We aimed to assess whether electroencephalogram (EEG) is a useful tool in predicting neurological outcome in patients with post-hypoxic myoclonus (PHM). DESIGN AND SETTING: This study was conducted as part of an internal hospital audit assessing therapeutic hypothermia in patients with hypoxic cardiac arrest...
March 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30857511/neither-vitamin-d-levels-nor-supplementation-are-associated-with-the-development-of-persistent-critical-illness-a-retrospective-cohort-analysis
#5
Elizabeth M Viglianti, Paul Zajic, Theodore J Iwashyna, Karin Amrein
OBJECTIVE: The purpose of this study was to evaluate if vitamin D deficiency is associated with increased rates of persistent critical illness, and whether repletion of vitamin D among patients with this deficiency leads to decreased persistent critical illness. DESIGN: Retrospective cohort analysis. SETTING: Seven intensive care units (ICUs) at the University Medical Center of Graz, Austria, with participants recruited between July 2008 and April 2010...
March 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30857510/modifications-to-predefined-rapid-response-team-calling-criteria-prevalence-characteristics-and-associated-outcomes
#6
Anamika Ganju, Karoline Kapitola, Richard Chalwin
OBJECTIVE: Standardised rapid response team (RRT) calling criteria may not be applicable to all patients, and thus, modifications of these criteria may be reasonable to prevent unnecessary calls. Little data are available regarding the efficacy or safety of modifying RRT calling criteria; therefore, this study aimed to detail the prevalence and characteristics of modifications to RRT call triggers and explore their relationship with patient outcomes. DESIGN AND OUTCOME MEASURES: A pilot retrospective cohort study within a convenience sample of patients attended by a hospital RRT between July and December 2014; rates of repeat RRT calling and in-hospital mortality were compared between patients with and without modifications to standard calling criteria...
March 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30857509/a-novel-biometric-approach-to-estimating-tidal-volume
#7
Darragh E O'Brien, Jeffrey Kp Kam, Reuben J Slater, Antony E Tobin
BACKGROUND: Low tidal volume ventilation (LTVV) of 4-8 mL/kg of ideal body weight (IBW) reduces mortality in patients with acute respiratory distress syndrome, and, more recently, it has been recommended as the default therapy for all controlled ventilation. However, adherence to LTVV is poor. Barriers to adherence include not having height measurements taken or IBW calculated during admission. The aim of our project was to develop and validate a simple one step biometric measuring tool to directly estimate tidal volume (VT ) in ventilated patients based on their demispan...
March 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30857508/-likely-overassistance-during-invasive-pressure-support-ventilation-in-patients-in-the-intensive-care-unit-a-multicentre-prospective-observational-study
#8
Wisam Al-Bassam, Fabian Dade, Michael Bailey, Glenn Eastwood, Eduardo Osawa, Chris Eyeington, James Anesty, George Yi, Jolene Ralph, Nima Kakho, Vishnu Kurup, Elisa Licari, Emma C King, Cameron Knott, Timothy Chimunda, Julie Smith, Ashwin Subramaniam, Mallikarjuna Reddy, Cameron Green, Geoffrey Parkin, Yahya Shehabi, Rinaldo Bellomo
OBJECTIVE: To evaluate the prevalence of "likely overassistance" (categorised by respiratory rate [RR] ≤ 17 breaths/min or rapid shallow breathing index [RSBI] ≤ 37 breaths/min/L) during invasive pressure support ventilation (PSV), and the additional prevalence of fixed ventilator settings. DESIGN: Multicentre prospective observational study of invasive PSV practice in six general Victorian intensive care units with blinding of staff members to data collection...
March 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30857507/the-normal-cardiac-index-in-older-healthy-individuals-a-scoping-review
#9
Luca Cioccari, Nora Luethi, Neil J Glassford, Rinaldo Bellomo
OBJECTIVE: Despite the growing number of older patients having major surgery, the normal resting values for the cardiac index of older patients remain unclear. We aim to derive a normative value for such patients. DESIGN: Scoping review. DATA SOURCES: We searched MEDLINE, EMBASE and CENTRAL for studies reporting measured values of cardiac output or cardiac index in healthy, older humans at rest. RESULTS: We retrieved 5340 citations and assessed 412 fulltext articles for eligibility...
March 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30857506/the-angoff-method-in-the-written-exam-of-the-college-of-intensive-care-medicine-of-australia-and-new-zealand-setting-a-new-standard
#10
Christian Karcher
No abstract text is available yet for this article.
March 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30857505/-set-and-forget-is-not-an-ideal-approach-to-pressure-support-ventilation-the-ongoing-saga-of-high-tidal-volumes
#11
Jane E Lewis
No abstract text is available yet for this article.
March 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30857504/in-this-issue-of-ccr
#12
Rinaldo Bellomo
No abstract text is available yet for this article.
March 2019: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30482141/authors-reply-in-hospital-cardiac-arrests-events-worth-monitoring
#13
LETTER
David Pilcher, Ed Litton, Johnny Millar, Alastair McGeorge, Sue Huckson, Peter Hicks
No abstract text is available yet for this article.
December 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30482140/in-hospital-cardiac-arrests-events-worth-monitoring
#14
LETTER
Joe McCaffrey, Matthew J Maiden, Cathy Norrish
No abstract text is available yet for this article.
December 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30482139/risk-factors-for-candidaemia-and-their-cumulative-effect-over-time-in-a-cohort-of-critically-ill-non-neutropenic-patients
#15
Zeyad Aljeboori, Alexandra Gorelik, Emily Jenkins, Thomas McFarlane, Jai Darvall
OBJECTIVES: There is an increasing incidence of invasive candidal infections in critically ill patients worldwide, which has prompted development of various risk prediction rules, both clinical and microbiological. To date, however, there is a lack of research into how cumulative risk factors over time affect transition to candidaemia. The aim of this study was to investigate the association of risk factor accumulation over time with candidaemia in a cohort of critically ill, non-neutropenic adult patients...
December 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30482138/the-carbon-footprint-of-treating-patients-with-septic-shock-in-the-intensive-care-unit
#16
MULTICENTER STUDY
Forbes McGain, Jason P Burnham, Ron Lau, Lu Aye, Marin H Kollef, Scott McAlister
OBJECTIVE: To use life cycle assessment to determine the environmental footprint of the care of patients with septic shock in the intensive care unit (ICU). DESIGN, SETTING AND PARTICIPANTS: Prospective, observational life cycle assessment examining the use of energy for heating, ventilation and air conditioning; lighting; machines; and all consumables and waste associated with treating ten patients with septic shock in the ICU at BarnesJewish Hospital, St. Louis, MO, United States (US-ICU) and ten patients at Footscray Hospital, Melbourne, Vic, Australia (Aus-ICU)...
December 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30482137/intensive-care-implications-of-epidemic-thunderstorm-asthma
#17
MULTICENTER STUDY
Jai N Darvall, Matthew Durie, David Pilcher, Geoffrey Wigmore, Craig French, Dharshi Karalapillai, Forbes McGain, Edward Newbigin, Timothy Byrne, Vineet Sarode, Ben Gelbart, Andrew Casamento, John Dyett, Ashley Crosswell, Joseph Vetro, Joseph McCaffrey, Gopal Taori, Ashwin Subramaniam, Christopher MacIsaac, Anthony Cross, David Ku, Rinaldo Bellomo
OBJECTIVE: To investigate the environmental precipitants, treatment and outcome of critically ill patients affected by the largest and most lethal reported epidemic of thunderstorm asthma. DESIGN, SETTING AND PARTICIPANTS: Retrospective multicentre observational study. Meteorological, airborne particulate and pollen data, and a case series of 35 patients admitted to 15 intensive care units (ICUs) due to the thunderstorm asthma event of 21-22 November 2016, in Victoria, Australia, were analysed and compared with 1062 total ICU-admitted Australian patients with asthma in 2016...
December 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30482136/addressing-the-inadvertent-sodium-and-chloride-burden-in-critically-ill-patients-a-prospective-before-and-after-study-in-a-tertiary-mixed-intensive-care-unit-population
#18
Shailesh Bihari, Shivesh Prakash, Simon Potts, Elisha Matheson, Andrew D Bersten
BACKGROUND: Inadvertent fluid loading - and resultant sodium and chloride - is common in critically ill patients. Sources such as fluid used as vehicles for drug infusions and boluses (fluid creep) and maintenance fluid are a common cause. We hypothesised that total sodium and chloride loading can be safely reduced in critically ill patients both by the use of 5% glucose as a diluent for infusions and boluses, when possible, and by its use as a maintenance fluid. METHODS: This was a prospective before-and-after study design in a single centre tertiary mixed intensive care unit (ICU)...
December 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30482135/haemodynamic-effects-of-cold-versus-warm-fluid-bolus-in-healthy-volunteers-a-randomised-crossover-trial
#19
RANDOMIZED CONTROLLED TRIAL
Olof Wall, Lars Ehrenberg, Eva Joelsson-Alm, Johan Mårtensson, Rinaldo Bellomo, Christer Svensén, Maria Cronhjort
OBJECTIVE: To test the hypothesis that changes in cardiac index and mean arterial pressure (MAP) during and after a fluid bolus (FB) are altered by fluid temperature. DESIGN: Randomised, controlled, crossover trial. SETTING: Research laboratory at Swedish teaching hospital. PARTICIPANTS: Twenty-one healthy adult volunteers. INTERVENTIONS: Subjects were randomly allocated to 500 mL of Ringer's acetate at room temperature (22°C; cold) or body temperature (38°C; warm)...
December 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/30482134/communication-with-families-regarding-organ-and-tissue-donation-after-death-in-intensive-care-comfort-a-multicentre-before-and-after-study
#20
Julie E Potter, Lin Perry, Rosalind M Elliott, Anders Aneman, Jorge L Brieva, Elena Cavazzoni, Andrew Th Cheng, Michael J O'Leary, Ian M Seppelt, Robert G Herkes
OBJECTIVE: To implement a best-practice intervention offering deceased organ donation, testing whether it increased family consent rates. DESIGN: A multicentre before-and-after study of a prospective cohort compared with pre-intervention controls. SETTING: Nine Australian intensive care units. PARTICIPANTS: Families and health care professionals caring for donor-eligible patients without registered donation preferences or aged ≤ 16 years...
December 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
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