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European Journal of Heart Failure

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https://read.qxmd.com/read/30884077/how-does-neprilysin-inhibition-in-heart-failure-work
#1
EDITORIAL
A Mark Richards, Christopher Pemberton, Tim Yandle
No abstract text is available yet for this article.
March 18, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30884037/intravenous-iron-therapy-in-heart-failure-a-different-perspective
#2
Kambiz Ghafourian, Hsiang-Chun Chang, Hossein Ardehali
No abstract text is available yet for this article.
March 18, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30861239/cardiomyopathy-associated-with-long-term-right-ventricular-pacing-an-intriguing-clinical-issue
#3
EDITORIAL
Giuseppe Boriani, Marco Vitolo, Marco Proietti
No abstract text is available yet for this article.
March 12, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30859675/mineralocorticoid-receptor-antagonists-and-acute-heart-failure
#4
LETTER
Carlos Escobar, Luis Manzano
No abstract text is available yet for this article.
March 12, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30859669/the-role-of-ventricular-arterial-coupling-in-cardiac-disease-and-heart-failure-assessment-clinical-implications-and-therapeutic-interventions-a-consensus-document-of-the-european-society-of-cardiology-working-group-on-aorta-peripheral-vascular-diseases-european
#5
Ignatios Ikonomidis, Victor Aboyans, Jacque Blacher, Marianne Brodmann, Dirk L Brutsaert, Julio A Chirinos, Marco De Carlo, Victoria Delgado, Patrizio Lancelotti, John Lekakis, Dania Mohty, Petros Nihoyannopoulos, John Parissis, Damiano Rizzoni, Frank Ruschitzka, Petar Seferovic, Eugenio Stabile, Dimitrios Tousoulis, Dragos Vinereanu, Charalambos Vlachopoulos, Dimitrios Vlastos, Panagiotis Xaplanteris, Reuven Zimlichman, Marco Metra
Ventricular-arterial coupling (VAC) plays a major role in the physiology of cardiac and aortic mechanics, as well as in the pathophysiology of cardiac disease. VAC assessment possesses independent diagnostic and prognostic value and may be used to refine riskstratification and monitor therapeutic interventions. Traditionally, VAC is assessed by the non-invasive measurement of the ratio of arterial (Ea) to ventricular end-systolic elastance (Ees). With disease progression, both Ea and Ees may become abnormal and the Ea/Ees ratio may approximate its normal values...
March 12, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30848021/measurement-of-circulating-natriuretic-peptides-to-identify-community-based-patients-at-risk-of-incident-heart-failure-should-we
#6
EDITORIAL
Iain Squire
No abstract text is available yet for this article.
March 8, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30843353/bio-adrenomedullin-as-a-marker-of-congestion-in-patients-with-new-onset-and-worsening-heart-failure
#7
Jozine M Ter Maaten, Daan Kremer, Biniyam G Demissei, Joachim Struck, Andreas Bergmann, Stefan D Anker, Leong L Ng, Kenneth Dickstein, Marco Metra, Nilesh J Samani, Simon P R Romaine, John Cleland, Nicolas Girerd, Chim C Lang, Dirk J van Veldhuisen, Adriaan A Voors
BACKGROUND: Secretion of adrenomedullin (ADM) is stimulated by volume overload to maintain endothelial barrier function, and higher levels of biologically active (bio-) ADM in heart failure (HF) are a counteracting response to vascular leakage and tissue oedema. This study aimed to establish the value of plasma bio-ADM as a marker of congestion in patients with worsening HF. METHODS AND RESULTS: The association of plasma bio-ADM with clinical markers of congestion, as well as its prognostic value was studied in 2179 patients with new-onset or worsening HF enrolled in BIOSTAT-CHF...
March 6, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30843309/the-novel-butyrate-derivative-phenylalanine-butyramide-protects-from-doxorubicin-induced-cardiotoxicity
#8
Michele Russo, Fiorentina Guida, Lorella Paparo, Giovanna Trinchese, Rosita Aitoro, Carmen Avagliano, Antonella Fiordelisi, Fabiana Napolitano, Valentina Mercurio, Valentina Sala, Mingchuan Li, Daniela Sorriento, Michele Ciccarelli, Alessandra Ghigo, Emilio Hirsch, Roberto Bianco, Guido Iaccarino, Pasquale Abete, Domenico Bonaduce, Antonio Calignano, Roberto Berni Canani, Carlo G Tocchetti
AIMS: Butyric acid (BUT), a short chain fatty acid produced daily by the gut microbiota, has proven beneficial in models of cardiovascular diseases. With advancements in cancer survival, an increasing number of patients are at risk of anticancer drug cardiotoxicity. Here we assess whether the novel BUT derivative phenylalanine-butyramide (FBA) protects from doxorubicin (DOXO) cardiotoxicity, by decreasing oxidative stress and improving mitochondrial function. METHODS AND RESULTS: In C57BL6 mice, DOXO produced left ventricular dilatation assessed by echocardiography...
March 6, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30838721/electrophysiological-interventions-in-the-treatment-of-chronic-heart-failure-a-comparison-of-the-strength-of-evidence-supporting-cardiac-resynchronization-for-electrical-conduction-delay-and-catheter-ablation-for-atrial-fibrillation
#9
https://read.qxmd.com/read/30834697/beneficial-effects-of-sacubitril-valsartan-in-heart-failure-with-reduced-ejection-fraction-pas-%C3%A3-cause-du-bnp
#10
EDITORIAL
Naveen L Pereira, Viral K Desai, Allan S Jaffe
No abstract text is available yet for this article.
March 4, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30828920/increased-granulocyte-membrane-neprilysin-cd10-expression-is-associated-with-better-prognosis-in-heart-failure
#11
LETTER
Noemi Pavo, Alfred Gugerell, Georg Goliasch, Philipp Emanuel Bartko, Henrike Arfsten, Johannes Franz Novak, Mariann Gyöngyösi, Martin Hülsmann
No abstract text is available yet for this article.
March 3, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30815956/letter-on-idarucizumab-for-the-reversal-of-dabigatran-in-patients-undergoing-heart-transplantation
#12
LETTER
Eran Kalmanovich, Philippe Gaudard, François Roubille
No abstract text is available yet for this article.
February 27, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30811091/longitudinal-changes-of-right-ventricular-deformation-mechanics-during-trastuzumab-therapy-in-breast-cancer-patients
#13
Kalliopi Keramida, Dimitrios Farmakis, Jose Bingcang, Samir Sulemane, Stephanie Sutherland, Roma A Bingcang, Kanchana Ramachandran, Chara Tzavara, Georgios Charalampopoulos, Dimitrios Filippiadis, Nikolaos Kouris, Petros Nihoyannopoulos
BACKGROUND: Trastuzumab improves dramatically the prognosis of HER2-positive breast cancer patients, but it may lead to cardiotoxicity with left ventricular (LV) systolic dysfunction. Its effects on right ventricular (RV) function have not however been elucidated. We sought to assess LV and RV deformation mechanics during treatment with trastuzumab in breast cancer patients. METHODS AND RESULTS: We studied 101 consecutive women (mean age 54.3 ± 11.4 years) receiving trastuzumab for 12 months; 62 of them (61...
February 27, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30809928/heart-failure-risk-reduction-is-fit-and-overweight-or-obese-better-than-unfit-and-normal-weight
#14
EDITORIAL
Setor K Kunutsor, Jari A Laukkanen
No abstract text is available yet for this article.
February 27, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30790397/high-risk-of-heart-failure-associated-with-desmoglein-2-mutations-compared-to-plakophilin-2-mutations-in-arrhythmogenic-right-ventricular-cardiomyopathy-dysplasia
#15
Alexis Hermida, Véronique Fressart, Francoise Hidden-Lucet, Erwan Donal, Vincent Probst, Jean-Claude Deharo, Philippe Chevalier, Didier Klug, Nicolas Mansencal, Etienne Delacretaz, Pierre Cosnay, Patrice Scanu, Fabrice Extramiana, Dagmar I Keller, Stephanie Rouanet, Philippe Charron, Estelle Gandjbakhch
BACKGROUND: Previous studies suggested that genetic status affects the clinical course of arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) patients. The aim of this study was to compare the outcome of desmoglein-2 (DSG2) mutation carriers to those who carry the plakophilin-2 (PKP2) mutation, the most common ARVC/D-associated gene. METHODS AND RESULTS: Consecutive ARVC/D patients carrying a pathogenic mutation in PKP2 or DSG2 were selected from a national ARVC/D registry...
February 21, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30790396/rationale-and-design-of-the-european-multicentre-study-on-stem-cell-therapy-in-ischemic-non-treatable-cardiac-disease-science
#16
Christina Paitazoglou, Martin W Bergmann, Bojan Vrtovec, Steven A J Chamuleau, Bas van Klarenbosch, Wojtek Wojakowski, Aleksandra Michalewska-Włudarczyk, Mariann Gyöngyösi, Annette Ekblond, Mandana Haack-Sørensen, Kai Jaquet, Karsten Vrangbaek, Jens Kastrup
AIMS: Ischaemic heart failure (IHF) patients have a poor prognosis even with current guideline-derived therapy. Intramyocardial injections of autologous or allogeneic mesenchymal stromal cells might improve cardiac function leading to better clinical outcome. METHODS: The SCIENCE (Stem Cell therapy in IschEmic Non-treatable Cardiac diseasE) consortium has initiated a Horizon 2020 funded multicentre phase II study in six European countries. It is a double-blind, placebo-controlled trial testing the safety and efficacy of allogeneic Cardiology Stem Cell Centre Adipose-derived Stromal Cells (CSCC_ASC) from healthy donors or placebo in 138 symptomatic IHF patients...
February 20, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30779281/cardiorespiratory-fitness-body-mass-index-and-heart-failure-incidence
#17
Peter Kokkinos, Charles Faselis, Barry Franklin, Carl J Lavie, Labros Sidossis, Hans Moore, Pamela Karasik, Jonathan Myers
AIMS: Obesity is associated with increased risk of heart failure (HF). This risk may be modulated by improved cardiorespiratory fitness (CRF) as CRF is associated with favourable health outcomes. Thus, we assessed the interaction between body mass index (BMI), CRF and HF. METHODS AND RESULTS: Cardiorespiratory fitness and BMI were assessed in 20 254 US male veterans (mean age 58.0 ± 11.3 years), who completed a maximal exercise treadmill test between 1987 and 2017...
February 19, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30773798/klotho-fibroblast-growth-factor-23-and-the-renin-angiotensin-system-an-analysis-from-the-peace-trial
#18
Brian A Bergmark, Jacob A Udell, David A Morrow, Petr Jarolim, Julia F Kuder, Scott D Solomon, Marc A Pfeffer, Eugene Braunwald, Marc S Sabatine
AIMS: Klotho, an essential co-receptor for fibroblast growth factor (FGF)-23, has potentially beneficial inhibitory effects on the renin-angiotensin system. Limited data exist on the prognostic value of Klotho and FGF-23 levels in combination or their ability to predict benefit from angiotensin-converting enzyme (ACE) inhibition. METHODS AND RESULTS: A total of 3555 patients with stable ischaemic heart disease and left ventricular ejection fraction > 40% enrolled in the PEACE trial of trandolapril vs...
February 18, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30773783/individualizing-surgical-revascularization-in-patients-with-ischaemic-heart-failure-a-further-dive-into-stiches
#19
EDITORIAL
Søren L Kristensen
No abstract text is available yet for this article.
February 18, 2019: European Journal of Heart Failure
https://read.qxmd.com/read/30773754/medical-misinformation-vet-the-message
#20
EDITORIAL
Joseph A Hill
No abstract text is available yet for this article.
February 18, 2019: European Journal of Heart Failure
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