Alysha Chelliah, David A Wood, Liane S Canas, Haris Shuaib, Stuart Currie, Kavi Fatania, Russell Frood, Chris Rowland-Hill, Stefanie Thust, Stephen J Wastling, Sean Tenant, Karen Foweraker, Matthew Williams, Qiquan Wang, Andrei Roman, Carmen Dragos, Mark MacDonald, Yue Hui Lau, Christian A Linares, Ahmed Bassiouny, Aysha Luis, Thomas Young, Juliet Brock, Edward Chandy, Erica Beaumont, Tai-Chung Lam, Liam Welsh, Joanne Lewis, Ryan Mathew, Eric Kerfoot, Richard Brown, Daniel Beasley, Jennifer Glendenning, Lucy Brazil, Angela Swampillai, Keyoumars Ashkan, Sébastien Ourselin, Marc Modat, Thomas C Booth
BACKGROUND: The aim was to predict survival of glioblastoma at eight months after radiotherapy (a period allowing for completing a typical course of adjuvant temozolomide), by applying deep learning to the first brain MRI after radiotherapy completion. METHODS: Retrospective and prospective data were collected from 206 consecutive glioblastoma, IDH-wildtype patients diagnosed between March 2014-February 2022 across 11 UK centers. Models were trained on 158 retrospective patients from three centers...
January 29, 2024: Neuro-oncology