journal
https://read.qxmd.com/read/38065706/the-expression-mechanism-of-programmed-cell-death-1-ligand-1-and-its-role-in-immunomodulatory-ability-of-mesenchymal-stem-cells
#21
JOURNAL ARTICLE
Zhuo Chen, Meng-Wei Yao, Xiang Ao, Qing-Jia Gong, Yi Yang, Jin-Xia Liu, Qi-Zhou Lian, Xiang Xu, Ling-Jing Zuo
Programmed cell death 1 ligand 1 (PD-L1) is an important immunosuppressive molecule, which inhibits the function of T cells and other immune cells by binding to the receptor programmed cell death-1. The PD-L1 expression disorder plays an important role in the occurrence, development, and treatment of sepsis or other inflammatory diseases, and has become an important target for the treatment of these diseases. Mesenchymal stem cells (MSCs) are a kind of pluripotent stem cells with multiple differentiation potential...
November 23, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/38065705/comparison-of-curettage-vs-trephination-technique-for-harvesting-anterior-iliac-crest-bone-graft-a-cadaveric-study
#22
JOURNAL ARTICLE
Albert Cakar, Omer Faruk Egerci, Fırat Dogruoz, Ersin Tasatan, Serra Ozturk, Muzaffer Sindel, Ozkan Kose
PURPOSE: The purpose of this cadaveric study was to compare the volume and weight of bone graft harvested using the curettage vs. the trephination technique from the anterior iliac crest. METHODS: Embalmed cadavers were studied in this experimental research. The right hemipelvis of each cadaver was used for the trephine bone harvesting technique, whereas the left hemipelvis was used for the conventional curettage technique. The weight and the volume of the harvested bone were measured and statistically compared between the 2 sides...
November 23, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/38061929/road-traffic-mortality-in-zunyi-city-china-a-10-year-data-analysis-2013-2022
#23
JOURNAL ARTICLE
Tian-Jing Sun, Xiao-Fei Huang, Fang-Ke Xie, Ji Zhang, Xu-Heng Jiang, An-Yong Yu
PURPOSE: The study aimed to examine the pattern of motorization and the mortality rate related to road traffic crashes in Zunyi (a city in northern Guizhou province of China) from 2013 to 2022, and to identify the epidemiological characteristics of these crashes with to provide insights that could help improve road safety. METHODS: Data were obtained from the Zunyi traffic management data platform, and the mortality rates were calculated. We deployed various analytical methods, including descriptive analysis, Chi-square test or Fisher's exact test of categorical variable, circular distribution map analysis, and Rayleigh test to characterize the traits of road traffic crashes in the region...
November 23, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/38040589/global-trend-of-publications-in-orthopaedics-and-sports-medicine-1996-2021
#24
REVIEW
Raju Vaishya, Abhishek Vaish
We studied the publication trend in the field of orthopaedics and sports medicine over the last 25 years (1996 - 2021), by various countries, and regions of the world. There was an increasing trend in publications, across the globe. Some of the Asian countries like China, and India have shown a substantial growth in their research output. Europe continent has contributed the most publications in the last 25 years, whereas the United States as a country has been on the top of the list of contributors...
November 15, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/38052701/advances-in-mesenchymal-stem-cells-therapy-for-tendinopathies
#25
REVIEW
Xu-Feng Mao, Xi-Qian Zhang, Zhe-Yu Yao, Hai-Jiao Mao
Tendinopathies are chronic diseases of an unknown etiology and associated with inflammation. Mesenchymal stem cells (MSCs) have emerged as a viable therapeutic option to combat the pathological progression of tendinopathies, not only because of their potential for multidirectional differentiation and self-renewal, but also their excellent immunomodulatory properties. The immunomodulatory effects of MSCs are increasingly being recognized as playing a crucial role in the treatment of tendinopathies, with MSCs being pivotal in regulating the inflammatory microenvironment by modulating the immune response, ultimately contributing to improved tissue repair...
November 11, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/38016878/post-discharge-follow-up-of-patients-with-spine-trauma-in-the-national-spinal-cord-injury-registry-of-iran-during-the-covid-19-pandemic-challenges-and-lessons-learned
#26
JOURNAL ARTICLE
Zahra Azadmanjir, Moein Khormali, Mohsen Sadeghi-Naini, Vali Baigi, Habibollah Pirnejad, Mohammad Dashtkoohi, Zahra Ghodsi, Seyed Behnam Jazayeri, Aidin Shakeri, Mahdi Mohammadzadeh, Laleh Bagheri, Mohammad-Sajjad Lotfi, Salman Daliri, Amir Azarhomayoun, Homayoun Sadeghi-Bazargani, Gerard O'reilly, Vafa Rahimi-Movaghar
PURPOSE: The purpose of the National Spinal Cord Injury Registry of Iran (NSCIR-IR) is to create an infrastructure to assess the quality of care for spine trauma and in this study, we aim to investigate whether the NSCIR-IR successfully provides necessary post-discharge follow-up data for these patients. METHODS: An observational prospective study was conducted from April 11, 2021 to April 22, 2022 in 8 centers enrolled in NSCIR-IR, respectively Arak, Rasht, Urmia, Shahroud, Yazd, Kashan, Tabriz, and Tehran...
November 10, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/38040590/clinical-practice-of-sepsis-induced-immunosuppression-current-immunotherapy-and-future-options
#27
REVIEW
Fei Pei, Bin Gu, Shu-Min Miao, Xiang-Dong Guan, Jian-Feng Wu
Sepsis is a potentially fatal condition characterized by the failure of one or more organs due to a disordered host response to infection. The development of sepsis is closely linked to immune dysfunction. As a result, immunotherapy has gained traction as a promising approach to sepsis treatment, as it holds the potential to reverse immunosuppression and restore immune balance, thereby improving the prognosis of septic patients. However, due to the highly heterogeneous nature of sepsis, it is crucial to carefully select the appropriate patient population for immunotherapy...
November 8, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/37973473/risk-factors-for-brain-injury-in-patients-with-exertional-heatstroke-a-5-year-experience
#28
JOURNAL ARTICLE
Li Zhong, Ming Wu, Zhe-Ying Liu, Yan Liu, Zhi-Feng Liu
PURPOSE: Minimal data exist on brain injury in patients with exertional heatstroke (EHS) in developing country. In this study, we explored the risk factors for brain injury induced by EHS 90-day after onset. METHODS: A retrospective cohort study of patients with EHS was conducted in the intensive care unit of the General Hospital of Southern Theater Command in China from April 2014 to June 2019. Patients were divided into non-brain injury (fully recovered) and brain injury groups (comprising deceased patients or those with neurological sequelae)...
November 3, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/37953130/mannitol-inhibits-the-proliferation-of-neural-stem-cell-by-a-p38-mitogen-activated-protein-kinase-dependent-signaling-pathway
#29
JOURNAL ARTICLE
Hai-Zhen Duan, Xin Zhou, Quan Hu, Meng-Long Liu, Shu-Hong Wang, Ji Zhang, Xu-Heng Jiang, Tian-Xi Zhang, An-Yong Yu
PURPOSE: Mannitol is one of the first-line drugs for reducing cerebral edema through increasing the extracellular osmotic pressure. However, long-term administration of mannitol in the treatment of cerebral edema triggers damage to neurons and astrocytes. Given that neural stem cell (NSC) is a subpopulation of main regenerative cells in the central nervous system after injury, the effect of mannitol on NSC is still elusive. The present study aims to elucidate the role of mannitol in NSC proliferation...
November 2, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/37852876/arthroscopic-treatment-of-ankle-impingement-syndrome
#30
REVIEW
Xin Chen, He-Qin Huang, Xiao-Jun Duan
Arthroscopic treatment of ankle impingement syndrome (AIS) is a minimally invasive surgical procedure used to address symptoms caused by impingement in the ankle joint. This syndrome occurs when there is abnormal contact between certain bones or soft tissues in the ankle, leading to pain, swelling, or limited range of motion. Traditionally, open surgery was the standard approach for treating AIS. However, with advancements in technology and surgical techniques, arthroscopic treatment has become a preferred method for many patients and surgeons...
November 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/37940448/achilles-tendon-thickening-does-not-affect-elasticity-and-functional-outcome-after-surgical-repair-of-achilles-rupture-a-retrospective-study
#31
JOURNAL ARTICLE
Chen-Xi Wu, Chang-Yue Xiong, Bai Lu, Su-Meng Chen, Yu-Xin Yan, Lu Wang, Xin-Tao Zhang
PURPOSE: Previous studies have confirmed that Achilles tendon undergoes Achilles thickening after repair surgery of the rupture. Although this mechanism has been elucidated in the laboratory, there are few reports on its impact on clinical function. We designed a retrospective study to investigate the Achilles thickening after Achilles tendon rupture repair and its correlation between its elasticity and postoperative function. METHODS: In this retrospective analysis, patients who underwent surgical treatment for acute Achilles tendon rupture from April 2016 to April 2020 were included...
October 27, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/37925271/comparison-of-epidemiologic-features-between-upper-and-lower-limb-injuries-and-risk-factors-for-intensive-care-unit-admission-in-a-university-hospital-affiliated-with-the-national-trauma-registry-of-iran
#32
JOURNAL ARTICLE
Pouya Mahdavi Sharif, Mohsen Merati, Vali Baigi, Mohammadreza Zafarghandi, Vafa Rahimi-Movaghar, Moein Khormali, Marjan Laal, Payman Salamati
PURPOSE: Upper extremity injuries (UEIs) and lower extremity injuries (LEIs) constitute a considerable component of traumas. However, their epidemiologic differences and short-term in-hospital outcomes are not fully elucidated. This study aims to compare such discrepancies in a large-scale study. METHODS: In this retrospective study, all patients with UEIs and/or LEIs hospitalized from 24th July 2016 to 16th May 2020 in Sina Hospital, Tehran, Iran, and registered at the National Trauma Registry of Iran were enrolled in the study...
October 27, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/37926628/a-new-method-of-atfl-reconstruction-arthroscopically-artificial-ligament-reconstruction-with-tensional-remnant-repair
#33
JOURNAL ARTICLE
Qiu Huang, Xiao-Xi Ji, Wen-Hui Zhu, Ye-Hua Cai, Lie-Hu Cao, Yong-Cai Wang
PURPOSE: To investigate the clinical effects of arthroscopically artificial ligament reconstruction with tensional remnant-repair in patients who are obese, and/or with demand for highly intensive sports, and/or with poor-quality ligament remnants. METHODS: A retrospective case series study was performed on patients treated by arthroscopically anterior talofibular ligament (ATFL) reconstruction with tensional remnant repair technique from January 2019 to August 2021...
October 26, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/37839902/outcome-of-percutaneous-reconstruction-of-chronic-lateral-collateral-ligament-rupture
#34
JOURNAL ARTICLE
Soliudeen Adebayo Arojuraye, Ibrahim Abolaji Alabi, Ibrahim Usman Mustapha
PURPOSE: Many techniques have been described for the reconstruction of chronic lateral collateral ligament (LCL) rupture with different autograft options. The advantages of percutaneous LCL reconstruction include small incisions, minimal soft tissue disruption, less postoperative pain, and speedy rehabilitation and recovery. The aim of this study was to report the functional outcome of percutaneous LCL reconstruction and overall patient satisfaction in Africans. METHODS: This prospective and interventional study involving 51 patients with chronic LCL rupture who had percutaneous LCL reconstruction using peroneus longus autograft was conducted between January 2021 and December 2022 in National Orthopaedic Hospital, Dala-Kano, Nigeria...
September 26, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/37838578/a-quantitative-study-of-airway-ultrasound-in-predicting-difficult-laryngoscopy-a-prospective-study
#35
JOURNAL ARTICLE
Lin Ning, Xing Zhu, Hong-Chao Li, Shi-Jie Zhou, Qi-Wei Zhang, Hong-Yu Zou, Qing-Xiang Mao, Hong Yan
PURPOSE: As common clinical screening tests cannot effectively predict a difficult airway, and unanticipated difficult laryngoscopy remains a challenge for physicians. We herein used ultrasound to develop some point-of-care predictors for difficult laryngoscopy. METHODS: This prospective observational study included 502 patients who underwent laryngoscopy and a detailed sonographic assessment. Patients under 18 years old, or with maxillofacial deformities or fractures, limited mouth opening, limited neck movement or history of neck surgery were excluded from the study...
September 25, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/37838577/analysis-and-approach-to-renal-trauma-a-five-year-experience-at-a-level-i-trauma-centre-in-north-india
#36
JOURNAL ARTICLE
Piyush Gupta, Parvez Mohi Ud Din Dar, Sahil Gupta, Siddhart Jain, Subodh Kumar, Amit Gupta, Sushma Sagar
PURPOSE: Renal trauma constitutes 0.5% - 5% of all trauma patients, and 10% - 20% of abdominal trauma. It is the most commonly injured organ in the genitourinary tract. Road traffic crash (RTC) is the most common cause. In recent years due to the advances in radiological imaging and endovascular techniques, there has been an increase in the nonoperative management of renal trauma. We investigated a large trauma cohort at a level I trauma centre to evaluate patients' demographics with renal trauma, their management, and the outcomes...
September 23, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/37838579/acute-portal-vein-thrombosis-in-an-isolated-blunt-minor-liver-injury-near-the-porta-hepatis
#37
Onchuda Wongweerakit, Osaree Akaraborworn, Burapat Sangthong, Komet Thongkhao
Portal vein thrombosis (PVT) secondary to blunt abdominal trauma associated with liver injury is extremely rare in healthy individuals as well as in minor liver injury, and it carries a high rate of morbidity and mortality. Moreover, acute asymptomatic PVT is difficult to diagnose. We present a young trauma patient with isolated minor liver injury associated with acute PVT. A 27-year-old man presented to the emergency department after a motor vehicle collision. His primary survey findings were unremarkable...
September 20, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/37716873/a-foot-structure-study-of-new-arch-flexibility-grading-system-based-on-three-dimensional-arch-volume
#38
JOURNAL ARTICLE
Jun Liu, Miao Deng, Wei Wang, Xiang-Dong Liu, Lun Tao, Hong-Yi Xiang, Yan Xiong
PURPOSE: Different arch structures may cause different foot function injuries. In the past, the arch structure and flexibility of the foot were often defined by the height of the arch, and there was no three-dimensional structure classification method. In order to form a more complete three-dimensional description, we propose a new classification system of arch volume flexibility, and then use this new classification system to investigate the relationship between the arch volume flexibility (AVF) and arch index (AI), and the arch height flexibility (AHF) and AI, respectively...
September 4, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/37690867/the-value-of-the-infections-scoring-system-in-identifying-bacterial-infections-among-patients-presenting-at-the-emergency-department-of-a-middle-income-country-a-pilot-study
#39
JOURNAL ARTICLE
Dooshanveer C Nuckchady
PURPOSE: To investigate which scoring system is the most accurate tool in predicting mortality among the infected patients who present to the emergency department in a middle-income country, and to validate a new scoring system to predict bacterial infections. METHODS: This was a retrospective, single-center study among patients who were admitted via the emergency department of a public hospital. All patients who were started on antibiotics were included in the study, while patients aged less than 18 years old were excluded...
September 4, 2023: Chinese Journal of Traumatology
https://read.qxmd.com/read/37031048/optimal-entry-point-for-antegrade-and-retrograde-femoral-intramedullary-nails
#40
REVIEW
Mohammad M Alzahrani, Yousef Aljamaan, Jaffar Alsayigh, Shahad Alghamdi, Saad M Alqahtani, Steven R Papp
Surgical management of femoral shaft fractures with intramedullary nails has become the standard of care, with multiple options for entry point described, including piriformis entry, trochanter entry and retrograde femoral nails. Our present review describes the surgical anatomy of the proximal and distal femur and its relation to different entry points for intramedullary femoral nails. In addition, we reviewed relative indications for each technique, difficulties associated and possible complications.
September 2023: Chinese Journal of Traumatology
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