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Nuclear Medicine Review. Central & Eastern Europe

Agnieszka D Kolasińska-Ćwikła, Sonia J Konsek, John R Buscombe, Katarzyna Maciejkiewicz, Andrzej Cichocki, Katarzyna Roszkowska-Purska, Łukasz Sawicki, Michał Tenderenda, Jaroslaw B Cwikla
BACKGROUND: Neuroendocrine neoplasms of the pancreas (p-NEN) are common gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NENs). The aim of this retrospective study was to review the of value of Somatostatin Receptor Scintigraphy (SRS) in initial detection of p-NEN, evaluation of tumour extent and as imaging follow-up after radical surgery in patients with confirmed well (NETG1) or moderate (NETG2) differentiated p-NEN based on pathological WHO 2017 classification. MATERIAL AND METHODS: Overall 281 patients with confirmed p-NEN were enrolled...
October 2, 2018: Nuclear Medicine Review. Central & Eastern Europe
Bożena Birkenfeld
Radioisotope diagnosis and therapy in personalised medicine.
2018: Nuclear Medicine Review. Central & Eastern Europe
Zahra Kiamanesh, Zakieh Nasiri, Parinaz Jahanpanah, Sara Shakeri, Ramin Sadeghi
A 37-year-old female patient with four months history of paroxysmal pain in the left index finger was referred to our department for 99mTC-MDP scintigraphy. Radiographic studies of the patient showed a lytic tumour in the distal phalanx of the left second finger compatible with a glomus tumour. The scan showed mild decreased activity in the blood pool phase and minimal increased activity on the delayed images. The patient underwent surgery and a glomus tumour was removed. To the extent of our knowledge, this is the first case of bone scan in a glomus tumour of the finger reported in the literature...
2018: Nuclear Medicine Review. Central & Eastern Europe
Stanisław Piszczek, Sebastian Osiecki, Ewa Witkowska-Patena, Andrzej Mazurek, Przemysław Kwasiborski, Mirosław Dziuk
BACKGROUND: Myocardial perfusion scintigraphy remains one of the substantial noninvasive diagnostic methods in coronary artery disease. Recent technological advancement allowed to create novel semiconductor, dedicated cardiac gamma camera with better spatial resolution and higher energy resolution, resulting in the reduction of radiation burden and acquisition time. The aim of this study was to evaluate the efficacy and safety of stress-only supine and prone MPS with a cardiac gamma camera in patients with suspected or known coronary artery disease...
2018: Nuclear Medicine Review. Central & Eastern Europe
Chrissa Sioka, Eleonora Konstanti, Athanasios Papadopoulos, Vasilios Ragos, Konstantinos Papadimitropoulos, Vasilios Koulouras, Andreas Fotopoulos
BACKGROUND: Heterotopic ossification (HO) is a potential complication in patients hospitalized in an intensive care unit (ICU). In this study we examined the association of HO diagnosed with three-phase bone scan (3pBS) in association with various parameters in patients previously hospitalized in ICU. MATERIAL AND METHODS: We retrieved patient records of the last 12 years subjected to 3pBS and diagnosed with HO from the Department of Nuclear Medicine (2004 up to 2016) and searched for a name match from ICU records...
2018: Nuclear Medicine Review. Central & Eastern Europe
Michał Błaszczyk, Paweł Cichocki, Małgorzata Bieńkiewicz, Janusz Dąbrowski, Anna Płachcińska, Jacek Kuśmierek
BACKGROUND: Ultrasound is the first-line imaging in the diagnostics of the urinary system. It provides valuable morphological information, but its usefulness in assessment of the function of renal parenchyma is limited. Dynamic renal scintigraphy provides much more accurate information about parenchymal function of kidneys and urinary outflow. The aim of the study was to establish morphological ultrasound criteria for high likelihood of obstructive uropathy. MATERIAL AND METHODS: 59 patients (38 women, 21 men, between 18 and 82 years old, average age 50) with the pelvis dilatation > 10 mm in one or both kidneys newly diagnosed in ultrasound, without earlier history of kidney and urinary tract diseases or renal surgery...
2018: Nuclear Medicine Review. Central & Eastern Europe
Paweł Cichocki, Krzysztof Filipczak, Marian Surma, Anna Płachcińska, Jacek Kuśmierek
BACKGROUND: Dynamic renal scintigraphy provides effective diagnosis of obstructive uropathy and nephropathy. However, in case of a bilateral outflow impairment, relative differential renal function (DRF), which is a primary quantitative criterion for diagnosis of unilateral obstructive nephropathy (when its value is below 45%, according to EANM guidelines from 2011), becomes unreliable. In case of bilateral nephropathy with similar severity, this parameter may even be within the normal range (45-55%) for both kidneys...
2018: Nuclear Medicine Review. Central & Eastern Europe
Mai Amr Elahmadawy, Mohamed Samy Saied Elazab, Soha Ahmed, Mohamed Salama
BACKGROUND: Aim of the study was to evaluate the diagnostic performance of FDG PET-CT for the detection of local and distant disease relapse in surgically treated patients with renal cell carcinoma (RCC). MATERIAL AND METHODS: This retrospective study includes 96 patients underwent FDG PET-CT scanning in the post-surgical follow up within the first 6-12 months referred to nuclear medicine department, to perform PET/CT study. Each patient underwent FDG PET-CT with low dose CT, followed immediately by full dose Ce-CT...
2018: Nuclear Medicine Review. Central & Eastern Europe
Grzegorz Kamiński
No abstract text is available yet for this article.
2018: Nuclear Medicine Review. Central & Eastern Europe
Łukasz Hołody, Jolanta Kunikowska, Janusz Braziewicz
Breast cancer is the most common cancer in women in the western world. The estrogen receptor (ER) is expressed in two thirds of newly diagnosed breast cancers, so hormonal treatment is performed only in the receptor positive patients. The most successful ER imaging radiopharmaceutical in PET techniques is 16α-[18F]-flouro-17β-estradiol (¹⁸F-FES). The diffuse large B cell lymphoma (DLBCL) is one of the most common NHL, however, non-Hodgkin lymphoma constitutes only 4% of all primary cancers in women. The typical staging of disease is done using 18-fluorodeoksyglukose (¹⁸F-FDG) PET/CT...
2018: Nuclear Medicine Review. Central & Eastern Europe
Małgorzata Benke, Krzysztof Wocial, Weronika Lewandowska, Piotr Rutkowski, Paweł Teterycz, Piotr Jarek, Marek Dedecjus
BACKGROUND: Localization and histopathological examination of sentinel lymph node is a standard of melanoma treatment. The first stage of identification of the SLN is the preoperative lymphoscintigraphy. The aim of this study was to assess and compare diagnostic value of planar lymphoscintigraphy and SPECT/CT in sentinel lymph node biopsy procedure performed in patients with cutaneous trunk melanoma. MATERIAL AND METHODS: Between 2015 and 2016, patients with trunk melanoma (N = 255, F/M 95/160), aged from 17 to 88 after an excisional biopsy, with primary tumor ≥ pT1b (AJCC 2009, median Breslow thickness 2...
2018: Nuclear Medicine Review. Central & Eastern Europe
Toktam Massoudi, Hamed Shayegani, Ramin Sadeghi
BACKGROUND: The aim of this study was to evaluate the efficacy of "after washing" imaging in interpretation of dacryoscintigraphy as a functional imaging technique used in evaluation of tearing problems. MATERIALS AND METHODS: 300 nasolacrimal systems were studied. 100 μCi of technetium-99m sodium pertechnetate as drops of activity (10 μL) were placed into the inferior fornix of each eye. Dynamic images were obtained for 15 minutes in the sitting position...
2018: Nuclear Medicine Review. Central & Eastern Europe
Abdelhamid Biyi, Omar Ait Sahel, Abderrahim Mejjad, Yasser Benameur, Salah Nabih Oueriagli, Abderrahim Doudouh
A 77 years-old man with lung and bone involvement of proven IgG4-related disease complained of tree month's memory deficits. Brain MRI was normal. 18F-FDG whole body PET/CT showed in addition to the bone lesions, a marked symmetrical striatal hypermetabolism in contrast with cortical hypometabolism. Despite steroid treatment, the patient's clinical status declined rapidly and he died two months later. Striatal hypermetabolism has been reported in autoimmune limbic encephalitis, but to the best of our knowledge, this is the first description in a case of IgG4-related disease...
2018: Nuclear Medicine Review. Central & Eastern Europe
Agnieszka Kolasińska-Ćwikła, Anna Łowczak, Katarzyna Maciejkiewicz Maciejkiewicz, Jarosław Bogdan Ćwikła
Peptide Receptor Radionuclide Therapy (PRRT) is a form of molecular targeted therapy which is performed by using a small peptide (somatostatin analogue - SSA) that is coupled with a radionuclide beta emitting radiation. PRRT is a nuclear medicine for the systemic treatment of non-resectable, metastasized well/moderately differentiated, neuroendocrine tumours (NET) with overexpression of somatostatin receptor. These types of tumours include gastroenteropancreatic neoplasm (GEP-NENs), e.g. arising from the small bowel (often called carcinoid tumours), the pancreas, duodenum or stomach, but also from the large bowel or the lung and many other tissues (so called diffuse neuroendocrine system)...
2018: Nuclear Medicine Review. Central & Eastern Europe
Grzegorz Kamiński
No abstract text is available yet for this article.
2018: Nuclear Medicine Review. Central & Eastern Europe
Punit Sharma
Sclerosing Angiomatoid Nodular Transformation (SANT) is a rare benign vascular tumor of spleen. It consists of multiple angiomatoid nodules surrounded by dense fibrous tissue that often coalesces centrally to form a scar, which is considered to be a characteristic feature. These are usually asymptomatic and incidentally detected on imaging for other underlying pathology. SANTs can be 18F-Fluorodeoxyglucose (18F-FDG) avid on positron emission tomography-computed tomography (PET-CT) and thus can lead to false positive finding in oncological patients...
2018: Nuclear Medicine Review. Central & Eastern Europe
Mohsen Qutbi, Mehdi Soltanshahi, Mojtaba Ansari, Hoda Hashemi, Isa Neshandar Asli, Babak Shafiei
Dextrocardia, although a rare cardiac abnormality, carries the same risk for cardiac events as other people. SPECT Myocardial perfusion imaging is a potentially helpful diagnostic tool in patients with dextrocardia. Because of swapping of lateral and septal walls on SPECT slices, although visual analysis is possible, quantitation is substantially limited. Here, we introduce a simple practical method to make quantitative analysis feasible and accurate.
2018: Nuclear Medicine Review. Central & Eastern Europe
Stjepan Hmelik, Margareta Dobrenić, Dražen Huić
Pulmonary artery sarcomas (PAS's) are extremely rare malignant tumors that arise from the endothelial lining of the pulmonary arteries. On CT scans PAS's appear as intraluminal filling defects in the pulmonary arteries, mimicking pulmonary embolism (PE). Due to the similarities in radiographic features as well as in clinical presentation, PAS's are usually misdiagnosed as pulmonary embolism. Since PASs are F-18 FDG avid, F-18 FDG PET/CT scan is a useful imaging tool for differentiating between these two conditions, as shown in this case report...
2018: Nuclear Medicine Review. Central & Eastern Europe
Marian J Surma, Anna Płachcińska, Jacek Kuśmierek
BACKGROUND: Measurements of GFR may be performed with a slope/intercept method (S/I), using only two blood samples taken in strictly defined time points. The aim of the study was to modify this method in order to extend time intervals suitable for blood sampling. Modification was based on a variation of a Russel et al. model parameter, selection of time intervals suitable for blood sampling and assessment of uncertainty of calculated results. MATERIAL AND METHODS: Archived values of GFR measurements of 169 patients with different renal function, from 5...
2018: Nuclear Medicine Review. Central & Eastern Europe
Ewa Malinowska, Anna Doboszyńska, Anna Śliwińska, John R Buscombe, Grzegorz Kulesza, Beata Moczulska, Jarosław B Ćwikła
Sarcoidosis is a systemic disease of unknown aetiology characterised by the formation of noncaseating granulomas in various organs and tissues. The various imaging modalities that are useful in the investigation of lesions, staging and establishing indications for treatment include: conventional radiography, CT, MRI, and scintigraphy with ⁶⁷Ga, ²⁰¹Tl, 99mTc sestamibi, and somatostatin receptor scintigraphy (SRS) as well as ¹⁸F-FDG-PET/CT. This paper discusses the most commonly used technique of the scintigraphic, gallium (⁶⁷Ga) citrate) and its role in the evaluation and monitoring of patients with sarcoidosis...
2018: Nuclear Medicine Review. Central & Eastern Europe
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