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Journals Transplant Infectious Disease ...

Transplant Infectious Disease : An Official Journal of the Transplantation Society

https://read.qxmd.com/read/38191775/the-devil-is-in-the-details-nuances-of-pre-emptive-therapy-for-cytomegalovirus-disease-prevention-in-high-risk-seropositive-donors-liver-transplant-recipients
#41
EDITORIAL
Madeleine R Heldman, Ajit P Limaye
No abstract text is available yet for this article.
January 8, 2024: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38180288/failure-of-favipiravir-to-treat-chronic-norovirus-infection-in-a-kidney-transplant-patient
#42
LETTER
Amandine Darres, Arnaud Del Bello, Olivier Marion, Xavier de Lamballerie, Denis Malvy, Jacques Izopet, Nassim Kamar
No abstract text is available yet for this article.
January 5, 2024: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38180285/incidence-of-valganciclovir-related-leukopenia-and-neutropenia-in-solid-organ-transplant-recipients-at-high-risk-of-cytomegalovirus-disease
#43
JOURNAL ARTICLE
Sara Belga, Cristina Hernandez, Dima Kabbani, Carlos Cervera
BACKGROUND: Valganciclovir (VGCV) prophylaxis is associated with an increased risk of hematologic side effects. We analyzed the impact of VGCV prophylaxis on leukopenia and neutropenia rates and explored risk factors for its occurrence. METHODS: Retrospective cohort study of adult cytomegalovirus (CMV)-seronegative solid organ transplantation (SOT) recipients of either CMV-seropositive (CMV D+/R-) or CMV-seronegative (CMV D-/R-) donors between July 2005 and March 2019...
January 5, 2024: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38180168/five-year-single-center-analysis-of-cytomegalovirus-viremia-in-kidney-transplant-recipients-and-possible-implication-for-novel-prophylactic-therapy-approaches
#44
JOURNAL ARTICLE
Moritz Trappe, Patrick Affeldt, Franziska Grundmann, Martin Kann, Felix C Koehler, Roman-Ulrich Müller, Dirk Stippel, Rolf Kaiser, Elena Knops, Eva Heger, Gertrud Steger, Florian Klein, Christine Kurschat, Veronica Di Cristanziano
BACKGROUND: Cytomegalovirus (CMV) infections are a common complication after kidney transplantation (KTx) and negatively affecting patient outcome. Valganciclovir (VGC) prophylaxis is often limited by drug-induced side effects and dose reduction due to decline in kidney function. METHOD: In the present study, episodes of CMV viremia in the first year after KTx in a cohort of 316 recipients were analyzed retrospectively to identify risk factors linked to persistent infections...
January 5, 2024: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38180158/chatgpt-may-help-in-counseling-on-strategies-for-safe-living-following-solid-organ-transplantation
#45
LETTER
Matthew Chung Yi Koh, Jinghao Nicholas Ngiam, Lionel Hon-Wai Lum
No abstract text is available yet for this article.
January 5, 2024: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38179898/incidence-of-long-covid-19-among-heart-transplant-recipients
#46
LETTER
Jason Feinman, Aditya Parikh, Jessica Behar, Kimberly Ashley, Anuradha Lala, Noah Moss, Benjamin Natelson, Donna Mancini
No abstract text is available yet for this article.
January 5, 2024: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38160368/a-rare-case-of-elizabethkingia-meningoseptica-bacteremia-followed-by-meningitis-in-post-liver-transplant-patient
#47
LETTER
Sarita Nayak, Himanshu Sharma, Anand Shah
No abstract text is available yet for this article.
December 31, 2023: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38160331/donor-blood-cultures-and-outcomes-after-lung-transplantation-a-single-center-report
#48
JOURNAL ARTICLE
Mahmoud Hashim, Rana Ahmed Saleh, Rayid Abdulqawi, Chams Alkhalaf Albachir, Haifa Aldakhil, Khaled Manae AlKattan, Reem Saad Almaghrabi, Alaa Hamad, Waleed Saleh, Eid Abdullah Al-Mutairy
BACKGROUND: Transplanting lungs from donors with positive blood cultures has not been shown to adversely affect survival. There is limited evidence for potential effects on other outcomes, such as hospital course, graft function, and transmission of infection. METHODS: This retrospective cohort study included adult patients who underwent lung-only transplantation for the first time between March 2010 and December 2022. Outcomes of patients whose donors had positive blood cultures within 72 h of transplant were compared to patients whose donors had negative blood cultures...
December 31, 2023: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38160328/intrauterine-devices-are-a-safe-form-of-contraception-in-users-with-solid-organ-transplantation-a-single-center-experience
#49
JOURNAL ARTICLE
Stephanie I Amaya, Sharon F Wolff, Meghan Ross, Valerie A French
Patients who undergo organ transplantation are advised to use contraception for health optimization, yet limited data exists on safe contraceptive options for this population. This study investigates the infection risk of intrauterine devices (IUDs) in patients who have received a solid organ transplant by evaluating the incidence of pelvic inflammatory disease (PID). We performed a retrospective chart review of subjects with a solid organ transplant who used an IUD between the years of January 2007 to February 2021...
December 31, 2023: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38158932/impact-of-an-ultrasensitive-cytomegalovirus-quantitative-nucleic-acid-test-on-cytomegalovirus-detection-and-therapy-in-renal-transplant-recipients
#50
JOURNAL ARTICLE
Vivek B Beechar, Stephanie M Pouch, Varun K Phadke, Geeta Karadkhele, Christian P Larsen, Michael H Woodworth
BACKGROUND: Cytomegalovirus (CMV) infection has broad implications for morbidity and mortality in renal transplant recipients (RTR). Routine surveillance for CMV replication with PCR-based quantitative nucleic acid testing (qNAT) assays is standard practice in most transplant centers, but the impact of assay sensitivity on antiviral decision-making and virologic outcomes has not been studied. We investigated the effects of an ultrasensitive CMV qNAT assay on multiple clinical outcomes, including time to detection and duration of CMV DNAemia...
December 30, 2023: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38180287/epidemiology-of-bloodstream-infections-and-the-impact-of-antimicrobial-resistance-in-pediatric-hematopoietic-cell-transplant
#51
REVIEW
Fabianne Carlesse, Chiara Russo, Adriana Seber, Elio Castagnola
Bloodstream infections (BSI) pose a substantial threat to the well-being and survival of patients undergoing hematopoietic stem cell transplantation (HSCT). Risk factors for these infections vary across the different post-HSCT phases. In the pre-engraftment period, patients are particularly susceptible to infection due to prolonged neutropenia, mucosal damage, and extensive use of central venous line (CVL). In the post-engraftment phase, the emergence of graft versus host diseases further compounds the risk...
February 2024: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38152054/post-transplant-lymphoproliferative-disorder-in-pediatric-liver-transplant-recipients-experience-from-a-south-african-transplant-center
#52
JOURNAL ARTICLE
Priya Walabh, David P Moore, Christina Hajinicolaou
INTRODUCTION: Post-transplant lymphoproliferative disorder (PTLD) is a clinically heterogeneous potentially fatal complication of pediatric liver transplantation (PLT). We determined the prevalence, complications, and associated factors for PTLD in PLT recipients from Wits Donald Gordon Medical Centre, South Africa from January 2012 to August 2019. METHODS: We performed a retrospective record review of 150 PLT recipients. RESULTS: Histologically proven PTLD occurred in 17/150 PLT recipients (11...
December 28, 2023: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38152037/rapidly-progressive-graft-vasculopathy-in-a-heart-transplant-recipient-with-confirmed-sars-cov-2-infection
#53
LETTER
Micaela MacKay, Madison Clewis, Wissam Khalife
No abstract text is available yet for this article.
December 28, 2023: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38151992/evaluation-of-ear-nose-and-throat-screening-in-liver-transplantation-candidates-a-retrospective-cohort-study
#54
JOURNAL ARTICLE
Eline Beukman, Adriaan J van der Meer, R Bart Takkenberg, Caroline M den Hoed, Andries Paul Nagtegaal
BACKGROUND: Patients with end-stage liver disease can be treated with a liver transplantation (LT). Before listing, candidates are subjected to a screening procedure according to the EASL Clinical Practice Guidelines for LT. In our hospital, this includes an ear, nose, and throat (ENT) examination, directed towards the identification of (asymptomatic) infections and head and neck malignancies. METHODS: We retrospectively reviewed all ENT screening examinations in LT candidates from 2007 to 2022...
December 27, 2023: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38112078/twelve-month-kidney-and-liver-outcomes-of-kidney-transplantation-from-hepatitis-c-viremic-deceased-donors-to-aviremic-recipients
#55
JOURNAL ARTICLE
Laura A Binari, Peter Thorne, Scott A Rega, Irene D Feurer, Saed Shawar, Ruchi Naik, Kelly A Birdwell, J Harold Helderman, Anthony Langone, Bonnie Ann Sarrell, Heidi Schaefer, Bernard John DuBray, Kareem Eid, Laura Hickman, David Shaffer, Beatrice P Concepcion, Rachel C Forbes
INTRODUCTION: Utilization of hepatitis C viremic (HCV+) deceased donor kidneys (DDKT) for aviremic recipients increases opportunities for transplantation with excellent short-term outcomes. Our primary aim was to understand longer-term outcomes, specifically assessing kidney and liver function in the first year posttransplant. METHODS: This was a retrospective single-center study of adult DDKT recipients of HCV+ kidneys (cases) matched 1:1 to recipients of HCV- kidneys (comparators)...
December 19, 2023: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38112043/a-low-thrombospondin-1-serum-concentration-is-related-to-increased-bacteremia-risk-in-lymphoma-patients-treated-with-beeam-beam-conditioning-regimen-and-autologous-stem-cell-transplantation
#56
JOURNAL ARTICLE
Kacper Kościelny, Damian Mikulski, Mateusz Nowicki, Krystyna Wyka, Małgorzata Misiewicz, Ewelina Perdas, Agnieszka Wierzbowska, Wojciech Fendler
Infectious complications of autologous hematopoietic stem cell transplantation (AHSCT) are the most common adverse effects of the therapy, resulting in prolonged hospitalization and deterioration of patient well-being. Identifying predictors of these complications is essential for improving patient outcomes and guiding clinical management. This study aimed to examine thrombospondin-1 (THBS-1) serum levels as a potential biomarker for predicting bacteremia in AHSCT recipients. Blood samples were collected from 30 patients undergoing BeEAM/BEAM (bendamustine/carmustine, etoposide, cytarabine, melphalan) conditioning regimen at subsequent time points during AHSCT...
December 19, 2023: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38071458/clinical-impact-of-preservation-fluid-contamination-on-kidney-transplant-patients
#57
JOURNAL ARTICLE
Natalia Picola Brau, Maria Fiol Riera, Begoña Etcheverry Giadrosich, Lluis Riera Canals, Edoardo Melilli, Núria Sabé Fernández, Manel Castells Esteve, Francesc Vigués Julià
BACKGROUND: Kidney transplantation is associated with a high risk of infectious complications due to immunosuppressive therapy. Although infections may be transmitted from donor to transplant recipient through contaminated preservation solution (PS), the clinical impact of this is not well-understood. METHODS: We retrospectively evaluated PS contamination rates in a series of 339 patients who underwent cadaveric renal transplant at our centre. All patients with a positive culture received targeted preemptive therapy (PET)...
December 9, 2023: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38059638/difference-in-immunosuppressant-dose-requirement-when-transitioning-to-isavuconazole-from-other-azoles-in-thoracic-transplant-recipients
#58
JOURNAL ARTICLE
Jade M Kozuch, Carrie Burt, Kamyar Afshar, Saima Aslam, Gordon Yung, Mark Mariski, Eugene Golts, Ashley Feist
The triazole antifungal isavuconazole (ISAVU) is used for prevention and treatment of fungal infections in solid organ transplant (SOT). SOT recipients commonly need to transition from one azole to another due to breakthrough infection, toxicity, or other reasons. The purpose of our study was to evaluate the effect of ISAVU on immunosuppressant concentrations in thoracic transplant recipients when ISAVU was started de novo or transitioned from another azole. We conducted a single-center retrospective cohort study including 68 patients (51 lung, 14 heart, and 3 heart/lung transplant)...
December 7, 2023: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38055610/heart-of-the-matter-infection-and-xenotransplantation
#59
JOURNAL ARTICLE
Kapil K Saharia, Victoria G Hall, Supavit Chesdachai, Paige Porrett, Jay A Fishman, Stephanie M Pouch
In this clinicopathological conference, invited experts discussed a previously published case of a patient with nonischemic cardiomyopathy who underwent heart transplantation from a genetically modified pig source animal. His complex course included detection of porcine cytomegalovirus by plasma microbial cell-free DNA and eventual xenograft failure. The objectives of the session included discussion of selection of immunosuppressive regimens and prophylactic antimicrobials for human xenograft recipients, description of infectious disease risk assessment and mitigation in potential xenograft donors and understanding of screening and therapeutic strategies for potential xenograft-related infections...
December 6, 2023: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38054588/stopping-antibacterial-prophylaxis-in-pediatric-allogeneic-hematopoietic-cell-transplantation-an-internal-audit
#60
JOURNAL ARTICLE
Nina Wintjes, Katja Krämer, Hedwig Kolve, Daniela Mohring, Frieder Schaumburg, Claudia Rossig, Birgit Burkhardt, Andreas H Groll
BACKGROUND: Antibacterial prophylaxis in children and adolescents undergoing allogeneic hematopoietic cell transplantation (HCT) is controversial and not recommended by international guidelines. We analyzed relevant posttransplant outcomes following discontinuation of antibacterial prophylaxis at a major European pediatric transplant center. METHODS: The single-center retrospective audit included all pediatric allogeneic HCT patients (pts) transplanted between 2011 and 2020 before (≤2014) and after (≥2015) stopping routine antibacterial prophylaxis with penicillin, metronidazole, and ciprofloxacin upon start of the conditioning regimen...
December 6, 2023: Transplant Infectious Disease: An Official Journal of the Transplantation Society
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